Journal of Clinical and Translational Endocrinology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A minimum of two years of undertreated primary hypothyroidism, as a result of drug-induced malabsorption of L-thyroxine, may have metabolic and cardiovascular consequences
ConclusionDuring a median period of 31 months, there are relevant consequences for L-T4 treated adult hypothyroid patients resulting from hyperthyrotropinemia caused by medications impairing L-T4 absorption. This should be taken into account by future guidelines on hypothyroidism management. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - April 10, 2019 Category: Endocrinology Source Type: research

Clinical Characteristics and Outcomes of Care in Adult Patients with Diabetic Ketoacidosis: A Retrospective Study from a Tertiary Diabetes Center in Thailand
ConclusionsInadequate metabolic monitoring and iatrogenic hypoglycemia remain areas of concern for DKA management. Occurrence of hypokalemia was related to poor adherence to protocol guidance on potassium supplementation. A strengthened educational program for nursing and medical staffs should be emphasized. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - April 10, 2019 Category: Endocrinology Source Type: research

Prevalence of prediabetes and type 2 diabetes in two non-random populations aged 44–77 years in the Faroe Islands
ConclusionsAmong the Faroese populations studied, the prevalence of type 2 diabetes increased with age and was more prevalent among men. The detected prevalence was comparable to other Nordic countries for all age-groups. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - April 3, 2019 Category: Endocrinology Source Type: research

Prevalence of Prediabetes and Type 2 Diabetes in Two Non-Random Populations Aged 44-77 Years in the Faroe Islands
ConclusionsAmong the Faroese populations studied, the prevalence of type 2 diabetes increased with age and was more prevalent among men. The detected prevalence was comparable to other Nordic countries for all age-groups. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - March 22, 2019 Category: Endocrinology Source Type: research

C679X loss-of-function PCSK9 variant is associated with lower fasting glucose in black South African adolescents: Birth to Twenty Plus Cohort
ConclusionsOur results indicate for the first that the C679X variants associated with low fasting glucose levels during adolescents as had been known for LDL-C. In view that a similar finding was reported in older black South African adults, therefore, the correlation of lower fasting glucose and LDL-C levels with C679X is observed from an early age to adulthood. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - March 1, 2019 Category: Endocrinology Source Type: research

Serum Free Thiols in Type 2 Diabetes Mellitus: a Prospective Study
ConclusionsAlthough R-SH concentrations were associated with a favourable disease status, it did not add to the predictive capacity for long-term complications. Based on the current data R-SH seems unsuitable as a prognostic marker in T2DM. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - March 1, 2019 Category: Endocrinology Source Type: research

Gestational Diabetes Mellitus and Macrosomia Predispose to Diabetes in the Lebanese Population
ConclusionIn conclusion, GDM and macrosomia, but not PCOS, are significant risk factors for T2DM in our Lebanese cohort. Our results, reported for the first time in the Middle East, present insights into risk factors management and disease prevention. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - February 20, 2019 Category: Endocrinology Source Type: research

Do community health workers affect non-urgent, ambulatory healthcare utilization among low-income, minority patients with diabetes?
Publication date: Available online 7 February 2019Source: Journal of Clinical & Translational EndocrinologyAuthor(s): Ryan G. Chiu, Yinglin Xia, Lisa K. Sharp, Ben S. GerberAbstractCommunity health workers (CHWs) can reduce emergent care among low-income, ethnic minority patients with type 2 diabetes. A secondary analysis of a randomized controlled trial evaluated the effect of CHWs on non-urgent, ambulatory healthcare utilization. Within this trial, no effect on ambulatory care was found. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - February 8, 2019 Category: Endocrinology Source Type: research

The value of total thyroidectomy as the definitive treatment for Graves’ disease: a single centre experience of 594 cases
ConclusionThis high-volume surgeon experience demonstrates that total thyroidectomy is a safe and effective treatment for Graves’ disease. It is associated with a very low incidence rate of post-operative complications, most of which are transitory; therefore, it offers a rapid and definitive control of hyperthyroidism and its related symptoms. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - February 8, 2019 Category: Endocrinology Source Type: research

Dyslipidemia: the untreated metabolic dysfunction in people with type 2 diabetes in Latin America. ARETAEUS study outcomes
ConclusionDyslipidemia treatment in patients with T2D was delayed despite its known deleterious effect on atherosclerosis development and β-cell mass/function. Anti-hyperglycemic treatment was not intensified when targets were not attained. This prescriptive inertia needs to be corrected because attainment of HbA1c treatment goals becomes more difficult, favoring the development of diabetes complications. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - January 26, 2019 Category: Endocrinology Source Type: research

Thyroid vascularization is an important ultrasonographic parameter in untreated Graves’ disease patients
In conclusion, thyroid hypervascularization at onset of Graves’ disease is an important sonographic feature. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - January 20, 2019 Category: Endocrinology Source Type: research

Relationship Between Depression, Sleep Quality, and Hypoglycemia Among Persons with Type 2 Diabetes
Conclusions:In the Thailand cohort, depressive symptoms were associated with hypoglycemia frequency. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - January 3, 2019 Category: Endocrinology Source Type: research

High frequency of empty sella, with gender differences, in the early neuroradiology evaluation of patients with traumatic brain injury. A prospective study
In conclusion, ES is detectable in almost 40% of persons who undergo CT within 24 h from TBI. A number of intergender differences concerning ES and the hormones evaluated are apparent. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - December 31, 2018 Category: Endocrinology Source Type: research

Metabolic effects of glucagon in humans
Publication date: Available online 20 December 2018Source: Journal of Clinical & Translational EndocrinologyAuthor(s): María M. Adeva-Andany, Raquel Funcasta-Calderón, Carlos Fernández-Fernández, Elvira Castro-Quintela, Natalia Carneiro-FreireAbstractDiabetes is a common metabolic disorder that involves glucose, amino acids, and fatty acids. Either insulin deficiency or insulin resistance may cause diabetes. Insulin deficiency causes type 1 diabetes and diabetes associated with total pancreatectomy. Glucagon produces insulin resistance. Glucagon-induced insulin resistance promotes type 2 diabetes and diabetes associate...
Source: Journal of Clinical and Translational Endocrinology - December 20, 2018 Category: Endocrinology Source Type: research

Improvement of glycemic control by treatment for insomnia with suvorexant in type 2 diabetes mellitus
ConclusionsSuvorexant treatment for insomnia of subjects with T2DM significantly improved CGM-measured daily glycemic control, which was associated with changes in sympathomimetic tone and/or improved insulin sensitivity. The amelioration of insomnia may therefore be a target for improving glycemic control in T2DM patients with insomnia. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - December 19, 2018 Category: Endocrinology Source Type: research