Acute Care Model that Reduces Oncology-Related Unplanned Hospitalizations to Promote Quality of Care and Reduce Cost
Publication date: Available online 23 July 2019Source: Journal of Cancer PolicyAuthor(s): Yvonne M. Coyle, Gerald O. Ogola, Carl R. MacLachlan, Margaret M. Hinshelwood, Neil S. FlemingAbstractBackgroundAdvances in cancer treatment has resulted in more oncology patients receiving outpatient therapy; however, this can promote a greater use of costly hospital-based acute care.MethodsThe Oncology Evaluation and Treatment Center (OETC) was established in March 2012 at Baylor University Medical Center (BUMC), a large urban hospital, as a quality improvement intervention to reduce oncology patient acute care and cost. The OETC pr...
Source: Journal of Cancer Policy - July 24, 2019 Category: Cancer & Oncology Source Type: research

Efficiency and Productivity of Cancer Care in Europe
This study measure the efficiency and productivity of breast and lung cancer health care provision in Europe in order to inform related policy discussions. The included countries’ relative performance is measured against a best practice production frontier computed using distance functions where inputs are used to produce an output. The distance function is well suited to identify best practice in a complex production process such as cancer care with rapid change in technologies.Price data is not needed which is an advantage when evaluating the European health care sector where market prices often are non-existent. I...
Source: Journal of Cancer Policy - July 23, 2019 Category: Cancer & Oncology Source Type: research

Association between conflict of interest and published position on tumor-treating fields for the treatment of glioblastoma
ConclusionOur study shows an association between authors' published stance on the use of tumor-treating fields for the treatment of glioblastoma and financial ties to the manufacturer of this device. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - June 2, 2019 Category: Cancer & Oncology Source Type: research

The impact of the UK ‘two-week rule’ on stage-on-diagnosis of oral cancer and the relationship to socio-economic inequalities
Publication date: Available online 23 May 2019Source: Journal of Cancer PolicyAuthor(s): Steve Langton, Derek Lowe, Simon N Rogers, Annette Plüddemann, Clare BankheadAbstractBackgroundThe ‘two-week rule’ (TWR) fast-track cancer referral system for head and neck cancers was introduced by the UK government in 2000, to facilitate earlier diagnosis. However, little work has compared stage on diagnosis of cancer before and after the implementation of the system.Objectives•Describe the presentation of oral cancer in Merseyside from 1992-2012.•To evaluate whether stage on presentation has improved after...
Source: Journal of Cancer Policy - May 24, 2019 Category: Cancer & Oncology Source Type: research

Integration of Research Priorities in Low and Middle-Income Countries: A Qualitative Analysis of National Cancer Control Plans
Publication date: June 2019Source: Journal of Cancer Policy, Volume 20Author(s): Irene Prabhu Das, Lisa Stevens, Catherine Muha, Sudha Sivaram, Brenda KosteleckyAbstractIncorporating research objectives into national cancer control plans informs effective implementation, and ultimately, health outcomes. We sought to explore the inclusion and description of research priorities in select low- and middle-income countries’ (LMIC) cancer control plans to elucidate gaps and collaborative opportunities. LMIC plans published in English, in 2016 or later, and met World Bank and Human Development Index criteria, comprised the ...
Source: Journal of Cancer Policy - May 23, 2019 Category: Cancer & Oncology Source Type: research

of Research Priorities in Low and Middle-Income Countries: A Qualitative Analysis of National Cancer Control Plans
Publication date: Available online 15 May 2019Source: Journal of Cancer PolicyAuthor(s): Irene Prabhu Das, Lisa Stevens, Catherine Muha, Sudha Sivaram, Brenda KosteleckyAbstractIncorporating research objectives into national cancer control plans informs effective implementation, and ultimately, health outcomes. We sought to explore the inclusion and description of research priorities in select low- and middle-income countries’ (LMIC) cancer control plans to elucidate gaps and collaborative opportunities. LMIC plans published in English, in 2016 or later, and met World Bank and Human Development Index criteria, compri...
Source: Journal of Cancer Policy - May 17, 2019 Category: Cancer & Oncology Source Type: research

When Oncologic Treatment Options Outpace the Existing Evidence: Contributing Factors and a Path Forward
Publication date: Available online 26 April 2019Source: Journal of Cancer PolicyAuthor(s): Daphne L. van der Velden, Laura A. Levit, George J. Chang, Matthew A. Facktor, Karyn A. Goodman, Jeffrey Kaufman, Gottfried E. Konecny, Sharon W. Kwan, Margaret Mooney, Grace Smith, Stephen B. Solomon, Alda Tam, David Michael Waterhouse, Emile E. VoestAbstractOncology is one of the most multidisciplinary areas of medicine, with most patients encountering multiple treatment modalities during the course of their disease. Rapidly occurring innovations in cancer care are continuously expanding the number of treatment options available. H...
Source: Journal of Cancer Policy - April 27, 2019 Category: Cancer & Oncology Source Type: research

The Expanding Role of Cancer Control & the U.S. National Cancer Institute: Policy Implications for Global Cancer Care
Publication date: Available online 19 March 2019Source: Journal of Cancer PolicyAuthor(s): Arnold D. Kaluzny, Donna M. O’BrienAbstractThroughout the global community, cancer control has been recognized as an important component of cancer care for populations, patients and their families. The United States had a pioneering effort, created as a result of the 1971 National Cancer Act (The War on Cancer), when it mandated that the National Cancer Institute (NCI), in collaboration with other federal, state, and local public health agencies and private industry, conduct cancer control activities that included detection, pr...
Source: Journal of Cancer Policy - March 20, 2019 Category: Cancer & Oncology Source Type: research

Early breast cancer in England: Evidence into practice: What can national cancer registration and analysis service datasets tell us?
Publication date: June 2019Source: Journal of Cancer Policy, Volume 20Author(s): R. Smittenaar, M. Bomb, J. Rashbass, E. Kipps, D. DodwellAbstractThe English National Cancer Registration and Analysis Service (NCRAS) holds several datasets which provide detailed information on the cancer patient pathway. Ascertainment, data quality and completeness issues persist. However, there are still critical research questions that can be addressed using these data, which will help improve outcomes for patients. Registry data will help us understand whether the outcomes seen in highly selected patients in randomised controlled trials ...
Source: Journal of Cancer Policy - March 20, 2019 Category: Cancer & Oncology Source Type: research

Early breast cancer in England: evidence into practice. What can National Cancer Registration and Analysis Service datasets tell us?
Publication date: Available online 8 March 2019Source: Journal of Cancer PolicyAuthor(s): R. Smittenaar, M. Bomb, J. Rashbass, E. Kipps, D. DodwellAbstractThe English National Cancer Registration and Analysis Service (NCRAS) holds several datasets which provide detailed information on the cancer patient pathway. Ascertainment, data quality and completeness issues persist. However, there are still critical research questions that can be addressed using these data, which will help improve outcomes for patients. Registry data will help us understand whether the outcomes seen in highly selected patients in randomised controlle...
Source: Journal of Cancer Policy - March 9, 2019 Category: Cancer & Oncology Source Type: research

Availability of palliative care services in Zambia: A nationwide provincial and tertiary hospital survey
ConclusionsThis assessment confirms the dearth of palliative care services across Zambia. Less than half of its provincial hospitals offer community- or home-based services and only 55% offer opioid analgesics. Immediate and substantial improvements in policy, drug procurement and distribution, and service expansion are needed to ensure high-quality palliative care is available throughout Zambia. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - February 21, 2019 Category: Cancer & Oncology Source Type: research

Cancer research in Brazil: Analysis of funding criteria and possible consequences
In conclusion, there are deficits in governmental funding of cancer research and innovation in Brazil. Therefore, effective measures to coordinate funding policies and effective criteria for funding allocation should be implemented to avoid further negative consequences for the population and the public health scenario. Moreover, increased governmental and non-governmental funding could help to improve the current precarious situation that limits the population’s access to health goods and services. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - February 21, 2019 Category: Cancer & Oncology Source Type: research

Can Functional Status Predict for Lack of Benefit for Immunotherapy in Advanced Malignancies?
Publication date: Available online 8 February 2019Source: Journal of Cancer PolicyAuthor(s): Arun Kumar Arumugam Raajasekar, Aju Mathew (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - February 10, 2019 Category: Cancer & Oncology Source Type: research

Breast Cancer Awareness, Knowledge And Screening Practice Among Women Resident In An Urban Local Government Area Of Oyo State, Nigeria
Publication date: Available online 1 February 2019Source: Journal of Cancer PolicyAuthor(s): Ajibola Idowu (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - February 2, 2019 Category: Cancer & Oncology Source Type: research

How can clinical research improve European health outcomes in cancer?
Publication date: Available online 1 February 2019Source: Journal of Cancer PolicyAuthor(s): Peter Selby, Lifang Liu, Amy Downing, Ian Banks, Roger Wilson, Richard Stephens, Francoise Meunier, Justine Rochon, Eva Morris, Matt Seymour, Walter Gregory, Mark Lawler, Annette Boaz (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - February 2, 2019 Category: Cancer & Oncology Source Type: research

Participation Rate and Its Influencing Factors of a Model Demonstration Cervical Screening Programme in Rural China
ConclusionOur results indicate that the 2-year screening programme announced by the government cannot be achieved. The effort of the screening team in finding unscreened women by throughout the area could raise the participation rate reaching 49.5% within 6 years. Our study also revealed an association between the extreme temperatures at screening undertaken and the low participation rates. In planning cervical screening activities in an area should consider such the environmental factors. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - January 11, 2019 Category: Cancer & Oncology Source Type: research

Are essential medicines available, reliable and affordable in low-middle income countries?
Publication date: Available online 21 December 2018Source: Journal of Cancer PolicyAuthor(s): Tim Eden, Elizabeth Burns, Piera Freccero, Lorna Renner, Vivian Paintsil, Mae Dolendo, Trisha Scanlan, Aye Aye Khaing, Martha Pina, Afiqul Islam, Catherine Chunda-Liyoka, Francine Kouya, Elizabeth MolyneuxAbstractA critical challenge for reducing the cancer survival disparity between children living in low-middle income countries (LMICs) and those in high income countries (HICs) is the apparent lack of consistent supplies of reliable, good quality, effective and affordable essential medicines for curative, supportive and palliativ...
Source: Journal of Cancer Policy - December 22, 2018 Category: Cancer & Oncology Source Type: research

Cancer Control in Member Countries of Organization of Islamic Cooperation (OIC)—A status report & Istanbul Declaration by the First Ladies of OIC
This article summarizes the burden of cancer within the region and presents the İstanbul Declaration by OIC Countries. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - November 9, 2018 Category: Cancer & Oncology Source Type: research

Target Wise and Pound Foolish: A simple technique to evaluate the trade-off between clinical benefit and economic burden of monoclonal antibodies
ConclusionThe “common currency” of NNT provides a concise, clinically relevant approach for framing the debate between individual benefit and public health priorities. Some monoclonal antibodies for some hematology/oncology indications may not meet reasonable thresholds for widespread use. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - November 9, 2018 Category: Cancer & Oncology Source Type: research

Delivery of Cancer Care in Sri Lanka
Publication date: Available online 2 November 2018Source: Journal of Cancer PolicyAuthor(s): Sanjeeva Gunasekera, Sanjeewa Seneviratne, Thiw.a Wijeratne, Christopher M. BoothAbstractSri Lanka, a small island nation in South Asia, is in the process of transition from a low-middle to an upper middle income country. With these changes, the burden of non-communicable disease has increased significantly. Cancer incidence has nearly doubled in twenty-five years. The pattern of cancer is also changing with breast, lung and colorectal cancers showing marked increased incidence compared to traditionally common cancers of the oral c...
Source: Journal of Cancer Policy - November 3, 2018 Category: Cancer & Oncology Source Type: research

The experience of low-income men with prostate cancer transitioning from disease-specific coverage to comprehensive insurance under the affordable care act
ConclusionsTaken together, the results support the integration of disease-specific coverage transition plans, social support, navigation, and educational services into insurance benefits. In the face of resource constraints, disease-specific coverage models may provide critical access to medical services for select populations. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - October 27, 2018 Category: Cancer & Oncology Source Type: research

Cancer prevention policy in the EU: Best practices are now well recognised; no reason for countries to lag behind
Publication date: Available online 9 October 2018Source: Journal of Cancer PolicyAuthor(s): Carolina Espina, Isabelle Soerjomataram, David Forman, Jose M. Martín-MorenoAbstractThrough the application of science to public health practice, National Cancer Control Programmes provide the framework for the development of policies on cancer control, with the ultimate goal of reducing cancer morbidity and mortality, and improving quality of life. In the last decade, a substantial number of Member States in the European Union (EU) have formulated and/or updated their National Cancer Control Programmes, Plans or Strategies i...
Source: Journal of Cancer Policy - October 11, 2018 Category: Cancer & Oncology Source Type: research

Cost-effectiveness of healthcare interventions for rare cancers: evidence from a systematic literature review and meta-analysis
ConclusionCompared to NICE suggested thresholds and cost-effectiveness ratios of reimbursed interventions for common cancers, interventions for rare cancers seem to be value-for-money. More collaborative research is needed to realise their full potential for improving efficiency and equity in healthcare. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - August 29, 2018 Category: Cancer & Oncology Source Type: research

Teleoncology in sub-Saharan Africa: A literature review
ConclusionsTeleoncology experiences in SSAs suggest the importance of identifying best practices for each local setting. Tailored teleoncology projects should be integrated into whole oncological services to amplify screening, diagnosis, therapies, and palliative care. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - August 18, 2018 Category: Cancer & Oncology Source Type: research

Why is Research in Early-Stage Cancer Research so Low?
Publication date: Available online 2 August 2018Source: Journal of Cancer PolicyAuthor(s): Vinay Prasad, Stephan LindnerAbstractAccording to Budish, Roin and Williams (2015), drug development for early-stage cancer drugs is low because of missing financial incentives, and surrogates can overcome this distortion. We argue that technological barriers can also explain such low drug development. We first summarize medical literature describing these barriers and then augment their data to simultaneously assess the role of incentives versus barriers. Our results suggest that technological barriers suppress research in early-sta...
Source: Journal of Cancer Policy - August 3, 2018 Category: Cancer & Oncology Source Type: research

Time for a European initiative for research to prevent cancer: A manifesto for Cancer Prevention Europe (CPE)
Publication date: Available online 11 July 2018Source: Journal of Cancer PolicyAuthor(s): David Forman, Linda Bauld, Bernardo Bonanni, Hermann Brenner, Karen Brown, Joakim Dillner, Ellen Kampman, Marta Manczuk, Elio Riboli, Karen Steindorf, Hans Storm, Carolina Espina, Christopher P. WildAbstractA landmark resolution on cancer prevention and control was adopted by Member States at the World Health Assembly 2017, noting that “risk reduction has the potential to prevent around half of all cancers” and urging “to promote cancer research to improve the evidence base for cancer prevention and control”. P...
Source: Journal of Cancer Policy - July 12, 2018 Category: Cancer & Oncology Source Type: research

Trends in antineoplastic receipt after medicare payment reform: Implications for future oncology payment design
Publication date: Available online 28 September 2016Source: Journal of Cancer PolicyAuthor(s): Helen M. Parsons, Susanne Schmidt, Laura L. Tenner, Amy J. DavidoffAbstractBackgroundThe Medicare Modernization Act (MMA) reduced reimbursement for many antineoplastics delivered in outpatient settings, altering practice patterns for some cancers. To further evaluate the MMA’s effect, we focus on colon cancer, where longstanding fluorouracil-based regimens were augmented in 2004 with 3 newly-approved drugs (oxaliplatin, bevacizumab, and/or cetuximab). Staggered implementation of MMA reimbursement changes (physician offices ...
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

The health and economic implications of the use of tanning devices
ConclusionsThe use of tanning devices is a significant contributor to illness and premature mortality in the U.S., and also represents a major economic burden in terms of the costs of medical care and lost productivity. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

The Kenya cancer research and control stakeholder program: Evaluating a bilateral partnership to strengthen national cancer efforts
Publication date: Available online 25 March 2017Source: Journal of Cancer PolicyAuthor(s): C. Morgan, M. Cira, A. Karagu, F.C. Asirwa, N.R. Brand, N. Buchanan Lunsford, S.M. Dawsey, A. Galassi, A. Korir, L. Kupfer, P.J. Loehrer, D. Makumi, L. Muchiri, S. Sayed, H. Topazian, J. Welch, M.J. Williams, K. DuncanAbstractBackgroundIn response to a growing cancer burden and need for improved coordination among stakeholders in Kenya, the US National Cancer Institute and the Kenya Ministry of Health collaboratively hosted a stakeholder meeting in 2014 which identified four priority areas of need (research capacity building, patholo...
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Making the invisible visible: Oncology nursing efforts of NCI-designated cancer centers in LMICs
Publication date: Available online 27 March 2017Source: Journal of Cancer PolicyAuthor(s): Annette Galassi, Camille Morgan, Catherine MuhaAbstractAn increasing majority of new cancer cases and mortality occur in low- and middle-income countries (LMICs). Nurses provide most cancer care in LMICs, yet receive limited, if any, oncology education and training. To better understand the efforts taking place to address this need, the Center for Global Health (CGH) at the US National Cancer Institute (NCI) undertook a study of global oncology nursing projects at NCI-designated cancer centers. The 62 comprehensive and clinical NCI-d...
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Diet and exercise in cancer: Epidemiologic perspectives on optimizing survivorship via lifestyle
Publication date: Available online 6 May 2017Source: Journal of Cancer PolicyAuthor(s): Stacey A. Kenfield, Erin L. Van Blarigan, Meir J. Stampfer, June M. Chan (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Diverging EU health regulations: The urgent need for co ordination and convergence
Publication date: Available online 16 July 2017Source: Journal of Cancer PolicyAuthor(s): Anastassia Negrouk, Denis Lacombe, Françoise MeunierAbstractAt the time of mayor breakthroughs in knowledge of molecular biology leading to change in design and conduct of innovative clinical research, there is a clear need for optimal co-operation at the EU level as well as with each Member States. The current legal framework for health research is developed and revised by several DGs dealing with clinical trials, data protection, in-vitro diagnostic tests and biomarkers. Also medical devices and advanced therapy directive / r...
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Increasing access to immuno-oncology therapies in Brazil
Publication date: June 2018Source: Journal of Cancer Policy, Volume 16Author(s): Carlos G. Ferreira, Andreia C. De Melo, Stephen Stefani, Denizar Vianna, Gustavo Fernandes, Carlos G. GadelhaAbstractImmuno-therapeutics have revolutionized the field of oncology. The Brazilian cancer population would unquestionably benefit from an increase in the availability of cost-effective immuno-oncologic drugs. The challenge is how to incorporate these into the toolbox of health professionals, given the complexity and inequities of the Brazilian healthcare system, limiting financial resources and numerous health needs. We provide a seri...
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

From here to 2025: Personalised medicine and healthcare for an immediate future
Publication date: June 2018Source: Journal of Cancer Policy, Volume 16Author(s): Denis HorganAbstractTaking real advantage of Europe’s excellence to improve citizens’ lives presents challenges that Europe’s policymakers have not yet fully met. The European Union and Member States have shown some clarity of assessment in recognising the needs, and some laudable determination to improve the situation, and it has intermittently taken some real steps to deliver on its ambitions to turn its excellence into valuable innovations for the benefit of citizens. But as we move towards the third decade of the 21st cen...
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Colorectal neoplasia: Are young and female individuals remain at low risk for it?
ConclusionThe influence of age and gender on CRC development may not have the same power as before. These findings suggest that firstly, the threshold of colonoscopy needs to be increased, and then a screening program should be decided upon for this region regardless of age and gender. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Cancer research for better public health policy – A personal view on the role of the International Agency for Research on Cancer in cancer control
Publication date: June 2018Source: Journal of Cancer Policy, Volume 16Author(s): Elisabete Weiderpass (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Evaluating the frequency of breast cancer risk factors in women referred to mammography center for breast cancer screening: A report from south part of Iran
ConclusionDue to the low performance of women in using screening methods such as mammography and breast self-examination, it seems necessary to design programs in order to educate women about methods of breast cancer screening. Also, it appears essential to establish changes in lifestyle such as changing diet and pay more attention to physical activity that can reduce the risk of breast cancer. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Socioeconomic changes in Brazil impacted breast cancer indexes at the beginning of the 21st century?
ConclusionsHuman Development Index was related to increases in breast cancer mortality in Brazil. Besides, the changes in income inequality indexes occurred in Brazil were not sufficient to impact the age-standardized mortality and hospital admission rate due to breast cancer. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Trends in mammography use in the Brazilian public healthcare system
ConclusionsScreening mammography rates were much lower than recommended in target age groups for mammography in Brazil and both types of mammograms were recorded for women younger than usually recommended. More appropriate use of mammography and better use of resources, will likely improve the outcomes of breast cancer in Brazilian women in a country with wide socio-economic differences, as well as minimise the potential risks associated with mammography in younger women. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Poor physical function, relationship problems and alcohol use are predictors of increased overall mortality in Swedish cancer patients: 27-years follow-up study in Stockholm County
ConclusionsPoor physical function is a predictor of increased mortality among subjects with diagnosis of cancer. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Projections of burden of cancers: A new approach for measuring incidence cases for India and its states – Till 2025
ConclusionIn view of increasing burden of cancers, there is burning need to initiate focused on control measures to combat the same. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Resource utilization and disaggregated cost analysis for initial treatment of melanoma
ConclusionPatterns of resource utilization and costs for initial treatment of melanoma are changing, particularly due to systemic therapy. Understanding these patterns and forecasting of future changes are critical for sustainable budgetary planning. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

African cervical cancer prevention and control plans: A scoping review
ConclusionA comprehensive picture of African CCPC efforts will require engagement with Ministry of Health (MoH) in each country. Extant evidence suggests that lack of resources is a major barriers to plan development and deployment. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

The US Food and Drug Administration’s use of pathologic complete response as regulatory endpoint: Did it pay off?
Publication date: June 2018Source: Journal of Cancer Policy, Volume 16Author(s): Jia Luo, Vinay PrasadAbstractIn 2013, the US FDA granted pertuzumab (Perjeta, Genentech/Roche) accelerated approval (AA) for the neo-adjuvant treatment of HER2 positive breast cancer. Approval was later extrapolated to the adjuvant setting by the NCCN and many providers. Pertuzumab remains the first and only drug to utilize an improvement in the rate of pathologic complete response (pCR), as the endpoint for regulatory approval. At the time the FDA utilized pCR as the basis for approval, their own analysis had suggested no correlation at the t...
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Development of paediatric oncology shared-care networks in low-middle income countries
Publication date: June 2018Source: Journal of Cancer Policy, Volume 16Author(s): Elizabeth Burns, Meg Collington, Tim Eden, Piera Freccero, Lorna Renner, Vivian Paintsil, Mae Dolendo, Afiqul islam, Aye Aye Khaing, Jon RosserAbstractIn order to reach out and offer optimum access for children with cancer across each country the development of networks of paediatric oncology units rather than just a single centre in one city has been the practice in high income countries over the last 30–40 years and is now being considered by developing countries. At a workshop bringing delegates from 4 countries in Africa and Asia to ...
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Call for action to end discrimination against cancer survivors
Publication date: September 2018Source: Journal of Cancer Policy, Volume 17Author(s): Helen Saul, Lifang Liu, Françoise MeunierAbstractThe growing number of cancer survivors in Europe is a tribute to the success of advances in diagnosis and treatment. But many who have survived the disease go on to face discrimination in the workplace and in their financial affairs. Survivors of cancer may have ongoing physical and psychosocial needs but with appropriate support, many can return to active and fulfilled lives, often including work and travel. Long term collaborative research is needed to monitor the late effects of t...
Source: Journal of Cancer Policy - July 10, 2018 Category: Cancer & Oncology Source Type: research

Trends in antineoplastic receipt after medicare payment reform: Implications for future oncology payment design
Publication date: Available online 28 September 2016Source: Journal of Cancer PolicyAuthor(s): Helen M. Parsons, Susanne Schmidt, Laura L. Tenner, Amy J. DavidoffAbstractBackgroundThe Medicare Modernization Act (MMA) reduced reimbursement for many antineoplastics delivered in outpatient settings, altering practice patterns for some cancers. To further evaluate the MMA’s effect, we focus on colon cancer, where longstanding fluorouracil-based regimens were augmented in 2004 with 3 newly-approved drugs (oxaliplatin, bevacizumab, and/or cetuximab). Staggered implementation of MMA reimbursement changes (physician offices ...
Source: Journal of Cancer Policy - July 5, 2018 Category: Cancer & Oncology Source Type: research

The health and economic implications of the use of tanning devices
ConclusionsThe use of tanning devices is a significant contributor to illness and premature mortality in the U.S., and also represents a major economic burden in terms of the costs of medical care and lost productivity. (Source: Journal of Cancer Policy)
Source: Journal of Cancer Policy - July 5, 2018 Category: Cancer & Oncology Source Type: research

The Kenya cancer research and control stakeholder program: Evaluating a bilateral partnership to strengthen national cancer efforts
Publication date: Available online 25 March 2017Source: Journal of Cancer PolicyAuthor(s): C. Morgan, M. Cira, A. Karagu, F.C. Asirwa, N.R. Brand, N. Buchanan Lunsford, S.M. Dawsey, A. Galassi, A. Korir, L. Kupfer, P.J. Loehrer, D. Makumi, L. Muchiri, S. Sayed, H. Topazian, J. Welch, M.J. Williams, K. DuncanAbstractBackgroundIn response to a growing cancer burden and need for improved coordination among stakeholders in Kenya, the US National Cancer Institute and the Kenya Ministry of Health collaboratively hosted a stakeholder meeting in 2014 which identified four priority areas of need (research capacity building, patholo...
Source: Journal of Cancer Policy - July 5, 2018 Category: Cancer & Oncology Source Type: research

Making the invisible visible: Oncology nursing efforts of NCI-designated cancer centers in LMICs
Publication date: Available online 27 March 2017Source: Journal of Cancer PolicyAuthor(s): Annette Galassi, Camille Morgan, Catherine MuhaAbstractAn increasing majority of new cancer cases and mortality occur in low- and middle-income countries (LMICs). Nurses provide most cancer care in LMICs, yet receive limited, if any, oncology education and training. To better understand the efforts taking place to address this need, the Center for Global Health (CGH) at the US National Cancer Institute (NCI) undertook a study of global oncology nursing projects at NCI-designated cancer centers. The 62 comprehensive and clinical NCI-d...
Source: Journal of Cancer Policy - July 5, 2018 Category: Cancer & Oncology Source Type: research