Genetics of Brugada syndrome
Publication date: Available online 12 September 2016 Source:Journal of Arrhythmia Author(s): Jyh-Ming Jimmy Juang, Minoru Horie In 1992, the Brugada syndrome (BrS) was recognized as a disease responsible for sudden cardiac death, characterized by a right bundle-branch block with ST segment elevation in the leads V1 and V2. This syndrome is highly associated with sudden cardiac death, especially in young males. BrS is currently diagnosed in patients with ST-segment elevation showing type 1 morphology ≥2 mm in ≥1 leads among the right precordial leads V1 or V2 positioned in the 2nd, 3rd, or 4th intercostal space, and...
Source: Journal of Arrhythmia - September 12, 2016 Category: Cardiology Source Type: research
Comparison of the measured pre-ejection periods and left ventricular ejection times between echocardiography and impedance cardiography for optimizing cardiac resynchronization therapy
Conclusion ICG was useful for the optimization of CRT. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - September 12, 2016 Category: Cardiology Source Type: research
Long RP interval tachycardia. What is the mechanism?
Publication date: Available online 31 August 2016 Source:Journal of Arrhythmia Author(s): Javier Jiménez-Díaz, María-Arantzazu González-Marín, Juan J. González-Ferrer, Felipe Higuera-Sobrino A 41-year-old man with a history of tachycardia refractory to multiple antiarrhythmic drugs was sent to our institution. His 12-lead electrocardiogram demonstrated incessant narrow QRS complex tachycardia with negative P waves in the inferior leads and long RP interval. Occasionally, the tachycardia terminated after a P wave and then was restarted after a sinusal beat. An EP study was performed during tachycardia. Intracard...
Source: Journal of Arrhythmia - August 31, 2016 Category: Cardiology Source Type: research
Local conduction during acute myocardial infarction in rats: Interplay between central sympathetic activation and endothelin
Publication date: Available online 31 August 2016 Source:Journal of Arrhythmia Author(s): Theofilos M. Kolettis, Marianthi Kontonika, Vassilios La Rocca, Antonios P. Vlahos, Giannis G. Baltogiannis, Zenon S. Kyriakides We investigated the effects of autonomic dysfunction and endothelin on local conduction and arrhythmogenesis during myocardial infarction. We recorded ventricular tachyarrhythmias, monophasic action potentials, and activation sequences in wild-type and ETB-deficient rats displaying high endothelin levels. Central sympathetic inputs were examined after clonidine administration. Clonidine mitigated ear...
Source: Journal of Arrhythmia - August 31, 2016 Category: Cardiology Source Type: research
Relationship between right and left ventricular function in candidates for implantable cardioverter defibrillator with low left ventricular ejection fraction
Conclusions Among patients being considered for an ICD, there is a positive but moderate correlation between LVEF and RVEF. A considerable proportion of patients who qualify for an ICD based on low LVEF have preserved RVEF, and vice versa. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - August 31, 2016 Category: Cardiology Source Type: research
Comparison of hemodynamic effects of biventricular versus left ventricular only pacing in patients receiving cardiac resynchronization therapy: A before –after clinical trial
Conclusions LV only pacing is not inferior to BiV pacing, and the hemodynamic response was similar in the two groups. However, the LV mode has a number of advantages over the BiV mode. More evidence, based on large clinical trials, is needed to confirm our results. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - August 30, 2016 Category: Cardiology Source Type: research
Successful pacemaker lead extraction involving an ossified thrombus: A case report
Publication date: Available online 30 August 2016 Source:Journal of Arrhythmia Author(s): Hideo Okamura, John S. Van Arnam, Marie Christine Aubry, Paul A. Friedman, Yong-Mei Cha A 41-year-old woman who had been fitted with a pacemaker 18 years prior presented for lead extraction because of device infection. First, we tried laser sheath. However, it cannot cross the binding in the innominate vein. Then we switched to the rotating mechanical sheath. Although it crunched through binding tissue, the progress halted. We removed the sheath and found pieces of calcified tissue in the sheath lumen. After removing the calcif...
Source: Journal of Arrhythmia - August 30, 2016 Category: Cardiology Source Type: research
Long-term reliability of sweet-tip type screw-in leads
Conclusions The overall reliability and stability of sweet-tip type screw-in leads were satisfactory throughout the long-term follow-up period (median, 4 years). Because it was associated with less lead fractures, cut-down access from the cephalic vein may be recommended as the first-line approach when considering the importance of long-term durability of pacing leads. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - August 29, 2016 Category: Cardiology Source Type: research
Functional characteristics of left ventricular synchronization via right ventricular outflow-tract pacing detected by two-dimensional strain echocardiography
Conclusions These results suggest that the functional characteristics of RVOT pacing may be a more optimal pacing site than RVMS, regardless of the pacing QRS duration, in patients with atrioventricular conduction disorders. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - August 29, 2016 Category: Cardiology Source Type: research
Reply: Takotsubo syndrome and polymorphic ventricular tachycardia: The chicken or the egg
Publication date: Available online 24 June 2016 Source:Journal of Arrhythmia Author(s): Rintaro Hojo, Seiji Fukamizu, Masayasu Hiraoka (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - August 29, 2016 Category: Cardiology Source Type: research
Mortality and predictors of appropriate implantable cardioverter defibrillator therapy in Japanese patients with Multicenter Automatic Defibrillator Implantation Trial II criteria
Conclusions The mortality and incidence of appropriate ICD therapy were 20% and 37%, respectively, at 3 years in Japanese patients who met the MADIT II criteria during ICD implantation for primary prevention of sudden cardiac death. The presence of NSVT and dilated left ventricle independently predicted the incidence of appropriate ICD therapy after implantation. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - August 29, 2016 Category: Cardiology Source Type: research
Electrophysiologic similarities of overdose between digoxin and bufadienolides found in a Chinese aphrodisiac
This report will describe a case that illustrates the electrophysiologic similarities between bufadienolide toxicity and digoxin toxicity as well as the treatment of bufadienolide toxicity. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - August 29, 2016 Category: Cardiology Source Type: research
Identification and management of right ventricular perforation using pacemaker and cardioverter-defibrillator leads: A case series and mini review
Publication date: Available online 30 June 2016 Source:Journal of Arrhythmia Author(s): Mohammad Ali Akbarzadeh, Reza Mollazadeh, Salma Sefidbakht, Soraya Shahrzad, Negar Bahrololoumi Bafruee Right ventricular perforation is a rare but serious complication of permanent pacemaker and implantable cardioverter-defibrillator implantation, with a reported prevalence rate of 0.1–6%. Generally, there is a high incidence of asymptomatic lead perforation with otherwise normal function. Some patients present with a stabbing chest pain and shortness of breath or pacemaker malfunction. However, in some cases, tamponade or adj...
Source: Journal of Arrhythmia - August 29, 2016 Category: Cardiology Source Type: research
Cardiac conduction defects and Brugada syndrome: A family with overlap syndrome carrying a nonsense SCN5A mutation
Conclusion Phenotypic differences between the proband and his brother carrying the same nonsense SCN5A mutation could be explained by modifiers such as SCN1B, and DSG2 gene variants. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - August 29, 2016 Category: Cardiology Source Type: research
Red cell distribution width and all-cause mortality in patients with atrial fibrillation: A cohort study
Conclusions RDW and changes in RDW are independently associated with the risk of all-cause mortality in patients with atrial fibrillation. (Source: Journal of Arrhythmia)
Source: Journal of Arrhythmia - August 29, 2016 Category: Cardiology Source Type: research
