Prevalence of late-life depression and its correlates in a community-dwelling low-educated population aged 75+ years: the Piet à Study.
Data from the United Nations ’ World Population Ageing Report predict an impressive growth of the elderly population, especially the oldest-old. This phenomenon will be seen even more significantly in developing countries, which already harbor two thirds of the aged population (United Nations, 2015). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 23, 2018 Category: Neurology Authors: Filipi Leles da Costa Dias, Ant ônio Lúcio Teixeira, Henrique Cerqueira Guimarães, Ana Paula Borges Santos, Simone Rios Fonseca Ritter, João Carlos Barbosa Machado, Maira Tonidandel Barbosa, Paulo Caramelli Tags: Research paper Source Type: research
Attention-deficit hyperactivity disorder and suicidality: the mediating effects of psychiatric comorbidities and family function
Suicide is one of the leading causes of death among youths in many developed countries (World Health Organization, 2017). In Taiwan, suicide is currently the second leading cause of death in young people aged 15-24 years old (Ministry of Health and Welfare, 2017). Suicidal ideation and behavior at an early age is a strong risk factor for suicides in adolescents and young adults (Castell vi et al., 2017). Thus exploring factors relating to the occurrence of suicidal ideation and behaviors in children is crucial for the early identification and remediation of suicide risks in youths. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 23, 2018 Category: Neurology Authors: Ying-Yeh Chen, Yi-Lung Chen, Susan Shur-Fen Gau Tags: Research paper Source Type: research
Inhibition of activated astrocyte ameliorates lipopolysaccharide- induced depressive-like behaviors
Major depressive disorder (MDD) is a complex mood disorder estimated to affect millions of people, and a leading cause of disability and mortality worldwide (Harrison et al., 2018). Depression and neurodegenerative diseases such as Alzheimer's disease, Parkinson's diseases are common comorbid conditions. It is also an potent indication of latent neurodegeneration (Hurley and Tizabi, 2013). Based on the widely recognized monoaminergic hypothesis, serotonin selective reuptake inhibitors (SSRIs) and serotonin and noradrenaline selective reuptake inhibitors (SNRIs) became the mainstream pharmacological treatments for depressio...
Source: Journal of Affective Disorders - August 23, 2018 Category: Neurology Authors: Yun Wang, Jing Ni, Lingyan Zhai, Ce Gao, Liming Xie, Lu Zhao, Xiaoxing Yin Source Type: research
Can chronotype function as predictor of a persistent course of depressive and anxiety disorder?
Depressive and anxiety disorders are highly prevalent in Western societies (Hirschfeld, 2001). Their courses are often of a chronic or recurrent nature. They cause an enormous burden to patients, to those close to them and involve high societal costs (Creed et al., 2002; Penninx et al., 2011). A disturbed timing of the circadian rhythm is found in patients suffering from these disorders (Wirz-Justice, 2006). Circadian rhythmicity is controlled by the suprachiasmatic nucleus (SCN), an area of the brain located in the hypothalamus (Roenneberg et al., 2007). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 22, 2018 Category: Neurology Authors: S.J.M. Druiven, S.E. Knapen, B.W.J.H. Penninx, N. Antypa, R.A. Schoevers, H. Riese, Y. Meesters Tags: Aiming at: Journal of Affective Disorders Source Type: research
Investigating the association between age at first alcohol use and suicidal ideation among high school students: Evidence from the Youth Risk Behavior Survey
The adolescent developmental stage is characterized by different developmental issues such as risk taking, learning intimacy skills, dating, developing identity, and autonomy (Connolly and McIsaac, 2009; Steinberg, 2008). These experiences may be positive and fulfilling, but they are also likely to be stressful as adolescents are likely to be faced with intense emotions and conflict and they may not have knowledge, experience, or skills to manage these situations. This is likely to heighten the emergence of different health risk behaviors such as experience with victimization, substance use, and mental health issues that a...
Source: Journal of Affective Disorders - August 22, 2018 Category: Neurology Authors: Philip Baiden, Cecilia Mengo, Godfred O. Boateng, Eusebius Small Source Type: research
Editorial Board
(Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 21, 2018 Category: Neurology Source Type: research
Neurocognitive clusters: A pilot study of young people with affective disorders in an inpatient facility
Affective disorders are characterised by disturbances in mood and emotional state (i.e. episodes of depression, mania and/or anxiety). Early stages of affective disorders may also be accompanied by functional impairment and neuropsychological changes such as difficulties in mental flexibility (Hermens et al., 2011), attention (Thompson et al., 2005), memory (Thompson et al., 2005) and executive function (Sweeney et al., 2000). Furthermore, studies have shown that patients’ neuropsychological (or ‘neurocognitive’) course is one of the best predictors of long-term function, over and above current affective sym...
Source: Journal of Affective Disorders - August 19, 2018 Category: Neurology Authors: Ashleigh M. Tickell, Elizabeth M. Scott, Tracey Davenport, Frank Iorfino, Laura Ospina-Pinillos, Kate Harel, Lisa Parker, Ian B. Hickie, Daniel F. Hermens Tags: Research paper Source Type: research
Body attitude, body satisfaction and body awareness in a clinical group of depressed patients: An observational study on the associations with depression severity and the influence of treatment
Depressed patients frequently report a broad range of body-related symptoms and phenomena such as decreased feelings of vitality; negative appraisal of the body, loss of sexual interest; and physical complaints like chronic joint pain, limb pain, back pain and gastrointestinal problems (Trivedi, 2004). Furthermore, studies have shown a positive association between depression and psychomotor retardation (Bennabi et al., 2013; Lecrubier, 2006) as expressed in, among others, decreased gait, restricted sensorimotor space (Fuchs and Schlimme, 2009; Michalak et al., 2009) and increased standing phases and slumped posture with re...
Source: Journal of Affective Disorders - August 19, 2018 Category: Neurology Authors: M. Scheffers, M.A.J. van Duijn, M. Beldman, R.J. Bosscher, J.T. van Busschbach, R.A. Schoevers Source Type: research
What is the relationship between rejection and self-harm or suicidality in adulthood?
Suicide and self-harm are major health concerns with over 800,000 people worldwide dying by suicide annually (World Health Organization, 2014), with 6,639 recorded in the UK last year (Office for National Statistics, 2017). As suicide is one of the leading causes of death (Rudd et al., 2013) identifying risk factors for this behaviour has become a global health priority (World Health Organization, 2014). Suicidal ideation and self-harm are associated with a greater risk of suicide (Bergen et al., 2012; Owens et al., 2014; Ribeiro et al., 2016). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 19, 2018 Category: Neurology Authors: Rosanne Cawley, Eleanor E Pontin, Jade Touhey, Kate Sheehy, Peter Taylor Source Type: research
Divergent associations between ghrelin and neural responsivity to palatable food in hyperphagic and hypophagic depression
Major Depressive Disorder (MDD) is one of the major causes of disability worldwide due to the negative impacts on functioning and re-occurring nature (WHO, 2017). One of the key challenges for the successful treatment of MDD is the highly heterogeneous nature of the disorder. Efforts to distinguish endophenotypes have revealed several pathophysiological mechanisms underlying depression, including HPA axis dysregulation, inflammation, circadian rhythm disturbances and altered reward sensitivity (Dean and Keshavan, 2017; Goldstein et al., in press.; Schmidt et al., 2011). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 18, 2018 Category: Neurology Authors: Hilal Cerit, Kara Christensen, Priyanka Moondra, Anne Klibanski, Jill M. Goldstein, Laura M. Holsen Tags: Research paper Source Type: research
rTMS Effects in Patients with Co-Morbid Somatic Pain and Depressive Mood Disorders
Repetitive Transcranial Magnetic Stimulation (rTMS) is a non-invasive neuromodulation treatment that involves the induction of electrical currents in a targeted region of the brain with the ability to impact various functional processes (Chervyakov et al., 2015). rTMS has shown to provide clinical improvement among a variety of neurological and psychiatric disorders and has been FDA-approved for treatment resistant depression (TRD). rTMS continues to undergo trials for other treatment indications including post-traumatic stress disorder (PT SD), generalized anxiety disorder (GAD), bipolar depression, schizophrenia, stro...
Source: Journal of Affective Disorders - August 18, 2018 Category: Neurology Authors: Angela L. Phillips, Robert L. Burr, David L. Dunner Tags: Research paper Source Type: research
Phenomenology and diagnostic stability of paediatric bipolar disorder in a Spanish Sample
Bipolar Disorder (BD) is a genetic and chronic psychiatric illness of unknown aetiology. The symptoms of BD usually begin in adolescence or early adulthood.1-3 A DSM-5 diagnosis of BD is made based on the presence/history of manic episodes (BD-I) or hypomanic episodes in addition to the presence/history of major depressive episodes (BD-II).4 Although the DSM-5 diagnostic criteria have identified BD as a disorder separate from depressive disorders, the criteria for BD diagnosis in children, adolescents, and adults are the same. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 18, 2018 Category: Neurology Authors: Mar ía Ribeiro-Fernández, Azucena Díez-Suárez, César Soutullo Tags: Research paper Source Type: research
Serum and plasma brain-derived neurotrophic factor and response in a randomized controlled trial of riluzole for treatment resistant depression
Major depressive disorder (MDD) is a substantial public health problem, affecting over 300 million people globally each year (Depression Fact Sheet accessed February 7, 2018). Unfortunately, its pathogenesis remains poorly understood. The monoaminergic hypothesis, which has dominated the field of mood disorders research for many decades, does not fully explain the underlying neurobiology of MDD, as demonstrated by the modest and de layed effects of monoaminergic-based antidepressants. Emerging evidence supports the basis of a neurotropic hypothesis, which posits that mood disorders may result from neuronal atrophy induce...
Source: Journal of Affective Disorders - August 18, 2018 Category: Neurology Authors: Samuel T. Wilkinson, Carly Kiselycznyk, Mounira Banasr, Ryan D. Webler, Colin Haile, Sanjay J. Mathew Tags: Research paper Source Type: research
A comparison of the interviewer-administered phone and self-complete online versions of the computerised eMINI 6.0 in a sample of pregnant women
Computerised versions of structured interviews for mental health disorders offer a potentially cost-effective, standardised approach to data collection for research and clinical practice. A number of computerised psychiatric interviews, including the Composite International Diagnostic Interview (CIDI-Auto) (WHO 1997), Clinical Interview Schedule – Revised (CIS-R) (Lewis et al. 1988) and the M.I.N.I. International Neuropsychiatric Interview (MINI) (Sheehan 1998), can be self-administered by patients or research participants. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 18, 2018 Category: Neurology Authors: Nicole Reilly, Kristina Talcevska, Emma Black, Stephen Matthey, Marie-Paule Austin Source Type: research
Validating the Geriatric Depression Scale with Proxy-Based Data: A Case-Control Psychological Autopsy Study in Rural China
Psychological autopsy is a widely used method that collects data from postmortem proxy respondents, medical records, and other sources, to understand the causes and identify correlates of suicide (Conner et al., 2011; Isometsa, 2001). The validity of psychological autopsy research relies upon the validity of the information provided by informants about the deceased (Knoll, 2008). Previous literature have shown that psychiatric diagnoses can be made reliably and validly based on proxy data (Conner et al., 2001b; Zhang et al., 2003). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 18, 2018 Category: Neurology Authors: Lu Niu, Cunxian Jia, Zhenyu Ma, Guojun Wang, Zhenjun Yu, Liang Zhou Tags: Research paper Source Type: research
