Local sacroiliac injections in the treatment of spondyloarthritis. What is the evidence?
ConclusionThis kind of procedure should be kept in the therapeutic armament in the current setting of costly targeted systemic treatments of spondyloarthritis. However, definition of a clear position in the treatment strategy needs further well-conducted studies. (Source: Joint Bone Spine)
Source: Joint Bone Spine - June 30, 2019 Category: Orthopaedics Source Type: research

Nutritional Facets of Osteoporosis Management: Can Probiotics Help?
Publication date: Available online 28 June 2019Source: Joint Bone SpineAuthor(s): Julien Paccou (Source: Joint Bone Spine)
Source: Joint Bone Spine - June 29, 2019 Category: Orthopaedics Source Type: research

Essential knowledge for patients with rheumatoid arthritis or spondyloarthritis Results of a multicentric survey in France among health professionals and patients
Conclusion: The present study provides a corpus of knowledge considered essential for patients in the self-management of their arthritis. The selection of many items reflects recent emphasis on professional recommendations and the patients’ perspective. Future work should lead to the development of new updated KQs for patients with inflammatory arthritis. (Source: Joint Bone Spine)
Source: Joint Bone Spine - June 20, 2019 Category: Orthopaedics Source Type: research

Gender equity in clinical practice, research and training: Where do we stand in rheumatology?
Publication date: Available online 17 June 2019Source: Joint Bone SpineAuthor(s): Laura Andreoli, Pavel V Ovseiko, Neelam Hassan, Uta Kiltz, Leonieke van Mens, Laure Gossec, Laura C Coates (Source: Joint Bone Spine)
Source: Joint Bone Spine - June 19, 2019 Category: Orthopaedics Source Type: research

Does iron deficiency contribute to fatigue in patients with rheumatoid arthritis without anemia?
Publication date: Available online 18 June 2019Source: Joint Bone SpineAuthor(s): François Vidal, André. Gillibert, Muriel Quillard, Patrice Fardellone, Olivier Vittecoq, Thierry Lequerré (Source: Joint Bone Spine)
Source: Joint Bone Spine - June 19, 2019 Category: Orthopaedics Source Type: research

Knowledge of and expectations about functional restoration programs for chronic low back pain: a mirror survey of 150 patients and 80 physicians in 2017
Publication date: Available online 16 June 2019Source: Joint Bone SpineAuthor(s): Pierre Letellier, Florian Bailly, Marina Assadourian, Antoine Potel, Violaine Foltz, Sophia Ascione, Laetitia Morardet, Myrianne Le Ralle, Bruno Fautrel, Arnaud Dupeyron, Nada Ibrahim-Nasser, Isabelle Griffoul-Espitalier, Bernard Duplan, Johann Beaudreuil, Laure Gossec (Source: Joint Bone Spine)
Source: Joint Bone Spine - June 17, 2019 Category: Orthopaedics Source Type: research

Treatment of chronic recurrent multifocal osteomyelitis with bisphosphonates in children
ConclusionsPamidronate is a safe and efficient method of CRMO therapy, particularly in cases refractory to NSAIDs treatment. Treatment with pamidronate provides both symptomatic relief as well as normalisation of bone morphology. (Source: Joint Bone Spine)
Source: Joint Bone Spine - June 17, 2019 Category: Orthopaedics Source Type: research

Local sacro iliac injections in the treatment of spondyloarthritis. What is the evidence?
Conclusion. This kind of procedure should be kept in the therapeutic armament in the current setting of costly targeted systemic treatments of spondyloarthritis. However, definition of a clear position in the treatment strategy needs further well conducted studies. (Source: Joint Bone Spine)
Source: Joint Bone Spine - June 17, 2019 Category: Orthopaedics Source Type: research

The frequency of uveitis in patients with juvenile inflammatory rheumatic diseases
Conclusions: Ocular involvement (mostly uveitis) in juvenile inflammatory arthritis and other pediatric rheumatic diseases varied between 3% and 50% depending on the underlying condition; and was highest in pediatric Bechet’s. In JIA, the highest frequency of uveitis was in oligoarticular JIA; with anterior uveitis being the most frequent type of uveitis. There was variation geographically for uveitis in JIA. (Source: Joint Bone Spine)
Source: Joint Bone Spine - June 16, 2019 Category: Orthopaedics Source Type: research

Editorial Board
Publication date: July 2019Source: Joint Bone Spine, Volume 86, Issue 4Author(s): (Source: Joint Bone Spine)
Source: Joint Bone Spine - June 1, 2019 Category: Orthopaedics Source Type: research

Contents
Publication date: July 2019Source: Joint Bone Spine, Volume 86, Issue 4Author(s): (Source: Joint Bone Spine)
Source: Joint Bone Spine - June 1, 2019 Category: Orthopaedics Source Type: research

Non-surgical periodontal disease: a new treatment for rheumatoid arthritis?
Publication date: Available online 30 May 2019Source: Joint Bone SpineAuthor(s): Hubert Marotte (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 31, 2019 Category: Orthopaedics Source Type: research

Upper limbs myo-fasciitis and polyarthritis in ovarian cancer
Publication date: Available online 30 May 2019Source: Joint Bone SpineAuthor(s): Mickaël Chouk, Hecquet Sophie, Frank Verhoeven, Clément Prati, Daniel Wendling (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 31, 2019 Category: Orthopaedics Source Type: research

Primary hydatid cyst is in the tibialis posterior muscle
Publication date: Available online 31 May 2019Source: Joint Bone SpineAuthor(s): Gökhan Tonkaz, Recep Sade, Berhan Pirimoğlu, Gökhan Polat (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 31, 2019 Category: Orthopaedics Source Type: research

Fibrodysplasia ossificans progressiva at whole-body low-dose computed tomography
Publication date: Available online 20 May 2019Source: Joint Bone SpineAuthor(s): Amandine Chabernaud Negrier, Thomas Funck-Brentano, Robert Burns, Lokmane Taihi, Valérie Bousson (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 22, 2019 Category: Orthopaedics Source Type: research

Medical pathways of children with juvenile idiopathic arthritis before referral to pediatric rheumatology centers
Conclusion: Time to first PR visit is rather short compared to other countries but remains too long. Pediatric rheumatologists should offer primary care providers basic training on JIA and fast direct access to PR departments if JIA is suspected. (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 22, 2019 Category: Orthopaedics Source Type: research

Intraspinal calcinosis in systemic sclerosis
Publication date: Available online 21 May 2019Source: Joint Bone SpineAuthor(s): Johannes Gossner, Joëlle Krahlisch (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 22, 2019 Category: Orthopaedics Source Type: research

Modified Rheumatoid Arthritis Impact of Disease (RAID) Score, a Potential Tool for Depression and Anxiety Screening for Rheumatoid Arthritis
Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Khai-Jing Ng, Kuang-Yung Huang, Chien-Hsueh Tung, Bao-Bao Hsu, Cheng-Han Wu, Malcolm Koo, Chia-Wen Hsu, Ming-Chi Lu, Ning-Sheng Lai (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

Rheumatology residency in France: an assessment of the past and the unknowns of a new reform
Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Olivier Fogel, Samuel Bitoun, on behalf of the young rheumatologist’s section of the French Society of Rheumatology, (REF) (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

Importance of feelings of injustice in fibromyalgia, large internet survey on experiences of 4516 french patients
Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Françoise Laroche, Julien Guérin, Joël d AP Trouvin, Serge Perrot (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

Winds of change in imaging of calcium crystal deposition diseases
Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Fabio Becce, Anais Viry, Lisa K. Stamp, Tristan Pascart, Jean-François Budzik, MARS Collaboration, Aamir Raja (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

HLA-B*51 subtypes molecular analysis in a series of Italian patients with Behçet’s syndrome
Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Pietro Leccese, Maria Carmela Padula, Eustachio Vincenzo Santospirito, Rosa Colucci, Nancy Lascaro, Salvatore D’Angelo (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

Screening for psoriatic arthritis: targeting phenotypes may improve case detection
Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Rafic Baddoura, Antoine Ghanem, Eugenie Halaby, Boutros Soutou, Roland Tomb (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

Structural Progression in Axial Spondyloarthritis
Publication date: Available online 5 May 2019Source: Joint Bone SpineAuthor(s): Krystel Aouad, Nelly Ziade, Xenofon BaraliakosAbstractFunctional disability in axial spondyloarthritis is related to the structural progression caused by the disease, thus largely contributing to its global burden and still representing a major challenge in management. Diagnosis at an early inflammatory stage of the disease is the hallmark for a better disease control and management. The natural history of axial spondyloarthritis is now better understood with imaging studies and long-term follow-up data, with some predictive factors for structu...
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

Partners and nurses’ knowledge and representations of gout: a qualitative study
Conclusion: Partners and nurses’ knowledge of gout is based on daily experiences. Participants were eager to learn more about gout. Nurses’ education and education programs including partners may improve gout management and patient adherence to treatment. (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 5, 2019 Category: Orthopaedics Source Type: research

Editorial Board
Publication date: May 2019Source: Joint Bone Spine, Volume 86, Issue 3Author(s): (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 2, 2019 Category: Orthopaedics Source Type: research

Contents
Publication date: May 2019Source: Joint Bone Spine, Volume 86, Issue 3Author(s): (Source: Joint Bone Spine)
Source: Joint Bone Spine - May 2, 2019 Category: Orthopaedics Source Type: research

Serum retinol-binding protein 4 is associated with insulin resistance in patients with early and untreated rheumatoid arthritis
In this study, 403 individuals with newly diagnosed and untreated RA were consecutively recruited. We calculated the Disease Activity Score assessed using 28-joint counts for swelling and tenderness (DAS28). Levels of serum RBP4, interleukin-6 (IL-6) and tumor necrosis factor (TNF) α were tested. IR was defined as Homeostasis model assessment for insulin resistance (HOMA-IR) index greater than or equal 2.40.ResultsIn those 403 patients, 68 (16.9%) were male and the median age was 43 years (IQR: 36–52). There was an evidently positive correlation between increased serum levels of RBP4 and increasing sever...
Source: Joint Bone Spine - May 2, 2019 Category: Orthopaedics Source Type: research

Vitamin D Supplementation in France in Patients with or at Risk for Osteoporosis: Recent Data and New Practices
Publication date: Available online 30 April 2019Source: Joint Bone SpineAuthor(s): Jean-Claude Souberbielle, Catherine Cormier, Etienne Cavalier, Véronique Breuil, Françoise Debiais, Patrice Fardellone, Pascal Guggenbuhl, Rose-Marie-Javier, Erick Legrand, Eric Lespessailles, Julien Paccou, Thierry Thomas, Bernard Cortet, au nom du Groupe de recherche et d’information sur les ostéoporoses, (GRIO)AbstractWith intermittent vitamin D supplementation, serum 25-hydroxyvitamin D (25OHD) levels may remain stable only if the dosing interval is shorter than 3 months, the ideal perhaps being about 1 month. ...
Source: Joint Bone Spine - May 2, 2019 Category: Orthopaedics Source Type: research

Is prediction of clinical response to methotrexate in individual rheumatoid arthritis patients possible? A systematic literature review
Conclusions:No predictors were identified reliably predicting clinical response to methotrexate after 3 to 6 months in the individual patient: clinical predictors were weak. However, a promising epigenetic model was found that needs further validation. (Source: Joint Bone Spine)
Source: Joint Bone Spine - April 13, 2019 Category: Orthopaedics Source Type: research

There is no season for infectious spondylodiscitis
Publication date: Available online 11 April 2019Source: Joint Bone SpineAuthor(s): Dubost Jean-Jacques, Pereira Bruno, Couderc Marion, Soubrier Martin (Source: Joint Bone Spine)
Source: Joint Bone Spine - April 13, 2019 Category: Orthopaedics Source Type: research

Uptrend in mortality from systemic connective tissue diseases: a joinpoint regression analysis among the general population of Brazil, 1996-2016
Publication date: Available online 11 April 2019Source: Joint Bone SpineAuthor(s): Rodrigo Rezende, Carol Vieira, Ronaldo Gismondi, Evandro Klumb (Source: Joint Bone Spine)
Source: Joint Bone Spine - April 13, 2019 Category: Orthopaedics Source Type: research

Esophagus type cervical spondylosis
Publication date: Available online 11 April 2019Source: Joint Bone SpineAuthor(s): Hecheng Ma, Si Meng (Source: Joint Bone Spine)
Source: Joint Bone Spine - April 13, 2019 Category: Orthopaedics Source Type: research

Biological secondary contributors to osteoporosis in fractured patients, is an early systematic assay relevant?
Publication date: Available online 9 April 2019Source: Joint Bone SpineAuthor(s): Pierre-Emmanuel Cailleaux, David Biau, Leclerc Philippe, Anract Philippe, Roux Christian, Briot KarineAbstractObjective:To evaluate the prevalence of biological abnormalities leading to secondary osteoporosis in recently fractured patients.Methods:Adults older than 50, hospitalized for a nonvertebral fracture from July 2015 to October 2016, were assessed for bone fragility contributors in the Orthopedics Department. Bone mineral density (BMD) measurements and Vertebral Fracture assessment (VFA) were performed within 3 months. We assessed the ...
Source: Joint Bone Spine - April 11, 2019 Category: Orthopaedics Source Type: research

Polymyalgia rheumatica occurrence under multikinase inhibitors (sorafenib and erlotinib) treatment
Publication date: Available online 27 March 2019Source: Joint Bone SpineAuthor(s): Frank Verhoeven, Delphine Weil-Verhoeven, Clément Prati, Vincent Di Martino, Daniel Wendling (Source: Joint Bone Spine)
Source: Joint Bone Spine - April 6, 2019 Category: Orthopaedics Source Type: research

Early Clinical Response and Long-Term Radiographic Progression in Recent-Onset Rheumatoid Arthritis: Clinical Remission within Six Months Remains the Treatment Target
Publication date: Available online 27 March 2019Source: Joint Bone SpineAuthor(s): Julie Legrand, Thomas Kirchgesner, Tatiana Sokolova, Bruno Vande Berg, Patrick DurezAbstractObjectives: The primary objective was to evaluate the correlation between 5-year radiographic structural disease progression and early clinical remission in recent-onset rheumatoid arthritis (RA). The secondary objective was to assess the correlation between erosion development in joints free of damage at baseline and early clinical remission.Methods: A single-center retrospective study was performed in 133 patients meeting ACR criteria for RA of rece...
Source: Joint Bone Spine - March 28, 2019 Category: Orthopaedics Source Type: research

Rate of remission among rheumatoid arthritis patients being treated by rheumatologists in routine practice
Publication date: Available online 27 March 2019Source: Joint Bone SpineAuthor(s): Dubost Jean-Jacques, Pereira Bruno, Fan Angélique, Soubrier Martin (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 28, 2019 Category: Orthopaedics Source Type: research

Polymyalgia Rheumatica occurrence undermultikinase inhibitors (sorafenib and erlotinib) treatment
Publication date: Available online 27 March 2019Source: Joint Bone SpineAuthor(s): Frank Verhoeven, Delphine Weil-Verhoeven, Clément Prati, Vincent Di Martino, Daniel Wendling (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 28, 2019 Category: Orthopaedics Source Type: research

Isolated Muscle Hypertrophy Revealing Diffuse Large B-Cell Lymphoma
Publication date: Available online 27 March 2019Source: Joint Bone SpineAuthor(s): Julie Merindol, Anne Calleja, Madleen Chassang, Nihal Martis (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 28, 2019 Category: Orthopaedics Source Type: research

Associations of hyperuricemia, gout, and UA-lowering therapy with the risk of fractures: a meta-analysis of observational studies
Publication date: Available online 22 March 2019Source: Joint Bone SpineAuthor(s): Qunchuan Zong, Yibo Hu, Qifu Zhang, Xiuxiu Zhang, Jingwen Huang, Tao WangAbstractObjective:A systematic review and meta-analysis were conducted to investigate the associations of hyperuricemia, gout, and uric acid (UA)-lowering therapy with the risk of fractures.Methods:Electronic searches on PubMed, the Cochrane Library, and Embase were conducted from inception to January 2, 2019. Observational studies assessing the effects of hyperuricemia, gout, and UA-lowering therapy on fractures were included in the meta-analysis. Summary risk estimate...
Source: Joint Bone Spine - March 23, 2019 Category: Orthopaedics Source Type: research

Knee replacement incidence and social deprivation: results from a French ecological study
Publication date: Available online 22 March 2019Source: Joint Bone SpineAuthor(s): Murielle Michel, Joséphine Bryère, Milka Maravic, Christian MarcelliAbstractObjectives:Temporal and geographic variations in knee osteoarthritis (OA) incidence occur worldwide. Regional variations also exist for socioeconomic status. We analyzed the association between socioeconomic deprivation (SED) and knee replacement (KR) incidence and assessed the proportion of KR associated with affluence.Methods:Patients aged 15 years and over hospitalized for KR in 2013 were included. We linked each patient to a municipality of residenc...
Source: Joint Bone Spine - March 23, 2019 Category: Orthopaedics Source Type: research

Destructive arthropathy of the shoulder complicating a cervical ependymoma
Publication date: Available online 16 March 2019Source: Joint Bone SpineAuthor(s): Zeineb Alaya (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 16, 2019 Category: Orthopaedics Source Type: research

Epidural Corticosteroid Injections: Still Credible?
Publication date: Available online 9 March 2019Source: Joint Bone SpineAuthor(s): Hervé Bard, Marc Marty, Sylvie Rozenberg, Jean-Denis Laredo (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 9, 2019 Category: Orthopaedics Source Type: research

Corneal and scleral involvement in inflammatory rheumatic disease: Rheumatologists and ophthalmologists exchanging views
Publication date: Available online 1 February 2019Source: Joint Bone SpineAuthor(s): Gaëlle Clavel, Eric Gabison, Luca SemeranoAbstractCorneal and scleral disorders related to inflammatory rheumatic diseases vary both in frequency and in severity. Sicca syndrome and its complications are the most common ocular manifestations and, together with episcleritis, can usually be managed by topical treatments. In contrast, the various forms of scleritis and peripheral ulcerative keratitis generally require systemic glucocorticoid therapy and the initiation or intensification of immunosuppressive treatment. Corneal and scleral...
Source: Joint Bone Spine - March 8, 2019 Category: Orthopaedics Source Type: research

The risk of Sjogren's syndrome in the older adults with gout: A medicare claims study
ConclusionsGout was associated with more than 1.7-fold higher risk of incident SS in adults 65 years or older. This finding needs to be reproduced and the underlying mechanisms for this association need further study. (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 8, 2019 Category: Orthopaedics Source Type: research

Assessment of major salivary gland size in primary Sjögren's syndrome: Comparison between clinical examination and ultrasonography
ConclusionClinical measurement of parotidomegaly was concordant between two observers on a binary mode (presence/absence). However, concordance on direct measurement was weak. US could be a complementary examination. (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 8, 2019 Category: Orthopaedics Source Type: research

Editorial Board
Publication date: March 2019Source: Joint Bone Spine, Volume 86, Issue 2Author(s): (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 4, 2019 Category: Orthopaedics Source Type: research

Contents
Publication date: March 2019Source: Joint Bone Spine, Volume 86, Issue 2Author(s): (Source: Joint Bone Spine)
Source: Joint Bone Spine - March 4, 2019 Category: Orthopaedics Source Type: research

Pathogenic effects of anti-citrullinated protein antibodies in rheumatoid arthritis – role for glycosylation
Publication date: Available online 25 January 2019Source: Joint Bone SpineAuthor(s): Frédéric CoutantAbstractThe identification in 1998 of the main antigenic substrate recognized by autoantibodies was a dramatic turning point in our understanding of rheumatoid arthritis (RA) biology. Now, two decades later, antibodies to citrullinated proteins are viewed no longer as mere biomarkers for RA, but also as major pathophysiological factors involved in the development of bone loss and joint pain. These pathogenic effects are ascribable to abnormal autoantibody glycosylation via a pathway involving the Th17T cells. ...
Source: Joint Bone Spine - February 28, 2019 Category: Orthopaedics Source Type: research

Knee psoriatic enthesitis assessed using positron emission tomography (PET) – FNa merged to ultrahigh field magnetic resonance imaging (UHF-MRI)
Publication date: Available online 17 January 2019Source: Joint Bone SpineAuthor(s): Serge Cammilleri, Sophie Gabriel, Arnaud Le Troter, Christophe Chagnaud, Jean Pierre Mattei, David Bendahan, Sandrine Guis (Source: Joint Bone Spine)
Source: Joint Bone Spine - February 27, 2019 Category: Orthopaedics Source Type: research