Maintaining occlusal stability by selecting the most appropriate occlusal scheme in complete removable prosthesis
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Sara Sabir, Anissa Regragui, Nadia MerzoukAbstractThe search of an adequate occlusal scheme that maximizes dentures’ stability and patients’ satisfaction is an ultimate objective in every complete prosthodontic treatment. Many studies compared occlusal schemes in terms of retention, comfort and masticatory performance. The purpose of this article is to review literature about different occlusal schemes related to complete dentures’ stability and edentulous patients’ satisfaction, in order to select the most appropria...
Source: Japanese Dental Science Review - November 7, 2019 Category: Dentistry Source Type: research

Resin based restorative dental materials: characteristics and future perspectives
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Bhanu Pratap, Ravi Kant Gupta, Bhuvnesh Bhardwaj, Meetu NagAbstractThis review article compiles the characteristics of resin based dental composites and an effort is made to point out their future perspectives. Recent research studies along with few earlier articles were studied to compile the synthesis schemes of commonly used monomers, their characteristics in terms of their physical, mechanical and polymerization process with selectivity towards the input parameters of polymerization process. This review covers surface mo...
Source: Japanese Dental Science Review - October 22, 2019 Category: Dentistry Source Type: research

B cell dysregulation in primary Sjögren’s syndrome: A review
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Hazim Mahmoud IbrahemAbstractPrimary Sjögren’s syndrome is a chronic autoimmune disorder of unknown etiology and is characterized by progressive focal lymphocytic infiltration of the lacrimal and salivary glands. Comparison of B cell subsets from the peripheral blood and salivary glands of patients with primary Sjögren’s syndrome and those from healthy individuals shows dysregulation and derangement of B cell subsets in both peripheral circulation and in inflamed glandular tissues. This dysregulation is expressed as a ...
Source: Japanese Dental Science Review - October 22, 2019 Category: Dentistry Source Type: research

Immunomodulatory aspects in the progression and treatment of oral malignancy
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Nobuo Kondoh, Masako Mizuno-Kamiya, Naoki Umemura, Eiji Takayama, Harumi Kawaki, Kenji Mitsudo, Yasunori Muramatsu, Shinichiro SumitomoAbstractInflammation substantially affects the risk of oral malignancy. Pro-inflammatory cytokine, interferon (IFN)-γ, confers anti-tumor activity using several different mechanisms. Conversely, higher expression of interleukin (IL)-17 is associated with worse prognosis. Monocyte chemotactic protein (MCP)-1 correlates positively with poor long-term survival of head and neck squamous cell car...
Source: Japanese Dental Science Review - October 9, 2019 Category: Dentistry Source Type: research

Social contribution of forensic odontology in Japan
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Toshinobu Komuro, Hirofumi Tsutsumi, Hikaru Izawa, Seiko Katsumura, Hisako Saitoh, Koichi Sakurada, Keita Sato, Akira FurukawaAbstractHalf a century has passed since the department for education and research on forensic odontology was established at dentistry-related universities in Japan in 1964. In order to meet the demands of society, the number of universities with a department of forensic odontology increased up until around 2005. In 2007, the Japanese Society of Forensic Dental Science was established, and then a serie...
Source: Japanese Dental Science Review - October 9, 2019 Category: Dentistry Source Type: research

Obesity-induced asthma: Role of free fatty acid receptors
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Kentaro Mizuta, Atsuko Matoba, Sumire Shibata, Eiji Masaki, Charles W. Emala SrAbstractObesity is a major risk factor for the development of asthma, and worsens the key features of asthma including airway hyperresponsiveness, inflammation, and airway remodeling. Although pro- and anti-inflammatory adipocytokines may contribute to the pathogenesis of asthma in obesity, the mechanistic basis for the relationship between asthma and obesity remains unclear. In obese individuals, the increased amount of adipose tissue results in ...
Source: Japanese Dental Science Review - August 30, 2019 Category: Dentistry Source Type: research

Comparison of the quality assurance system of dental professionals in Japan, the EU and the ASEAN
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Jun TsurutaAbstractIn recent years, the society requires a flexible response of the dental society to deal with changes in disease structure in the super-aging society in Japan. Regarding quality of dental care, we need to ensure quality of clinical environment, dental professionals and the system. As globalization expands, the health care professionals move to another country to work. In the European Union(EU), the quality assurance system for the graduated European dentist through the activities in undergraduate education ...
Source: Japanese Dental Science Review - August 30, 2019 Category: Dentistry Source Type: research

Novel insight into the management of bisphosphonate-related osteonecrosis of the jaw (BRONJ)
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Hiromitsu Kishimoto, Kazuma Noguchi, Kazuki TakaokaSummaryBisphosphonate-related osteonecrosis of the jaw (BRONJ), characterized by refractory bone exposure, has recently emerged as a serious side effect of bisphosphonate (BPs) treatment. We discuss novel insights that may help to improve the efficacy of BRONJ treatment and prevention. Our report highlights the following: (1) The presence of exposed bone in patients taking BPs does not necessarily reflect BRONJ, and diagnoses of oral ulceration with bone sequestration and ma...
Source: Japanese Dental Science Review - May 18, 2019 Category: Dentistry Source Type: research

Smoking and periodontal microorganisms
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Takashi Hanioka, Manabu Morita, Tatsuo Yamamoto, Koji Inagaki, Pao-Li Wang, Hiroshi Ito, Toshiya Morozumi, Toru Takeshita, Nao Suzuki, Hideo Shigeishi, Masaru Sugiyama, Kouji Ohta, Toru Nagao, Nobuhiro Hanada, Miki Ojima, Hiroshi OgawaSummaryResolution of dysbiosis following treatment for periodontal disease and tobacco dependence has been reported in longitudinal intervention studies. In the present report, we evaluated the biological findings regarding the effect of smoking on the periodontal microbiome. A standardized ele...
Source: Japanese Dental Science Review - April 25, 2019 Category: Dentistry Source Type: research

R-spondin signaling as a pivotal regulator of tissue development and homeostasis
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Kenichi NaganoAbstractR-spondins (Rspos) are cysteine-rich secreted glycoproteins which control a variety of cellular functions and are essential for embryonic development and tissue homeostasis. R-spondins (Rspo1 to 4) have high structural similarity and share 60% sequence homology. It has been shown that their cysteine-rich furin-like (FU) domain and the thrombospondin (TSP) type I repeat domain are essential for initiating downstream signaling cascades and therefore for their biological functions. Although numerous studie...
Source: Japanese Dental Science Review - April 24, 2019 Category: Dentistry Source Type: research

☆Symposium: Imaging modalities for drug-related osteonecrosis of the jaw (5), utility of bone scintigraphy and 18F-FDG PET/CT in early detection and risk assessment of medication-related osteonecrosis of the jaw (secondary publication)
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Satoru Watanabe, Kenichi Nakajima, Seigo KinuyaSummaryMedication-related osteonecrosis of the jaw (MRONJ) is a significant side effect of antiresorptive and antiangiogenic drugs. Since MRONJ is intractable, early detection is the best way to limit progression. Bone scintigraphy and 18F- fluorodeoxyglucose positron-emission tomography can detect minimal and subclinical changes in bones earlier than conventional radiological modalities. A differential diagnosis including MRONJ is recommended when abnormally high uptakes are in...
Source: Japanese Dental Science Review - March 22, 2019 Category: Dentistry Source Type: research

Imaging modalities for drug-related osteonecrosis of the jaw (2), Overview of the position paper on medication-related osteonecrosis of the jaw and the current status of the MRONJ in Japan
This article presents an overview of the position paper on medication-related osteonecrosis of the jaw and the current status of the MRONJ in Japan. (Source: Japanese Dental Science Review)
Source: Japanese Dental Science Review - March 20, 2019 Category: Dentistry Source Type: research

Imaging modalities for drug-related osteonecrosis of the jaw (3), Positron emission tomography imaging for the diagnosis of medication-related osteonecrosis of the jaw
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Yoshimasa Kitagawa, Noritaka Ohga, Takuya Asaka, Jun Sato, Hironobu Hata, Joseph Helman, Kanako Tsuboi, Norio Amizuka, Yuji Kuge, Tohru ShigaSummaryMedication-related osteonecrosis of jaws (MRONJ) is one of the most complicated inflammatory conditions in oral and maxillofacial region. It is very difficult to correctly evaluate the degree and extent of necrosis and infection. This refractory osteonecrosis often needs extended surgery, leading to impaired quality-of-life. We have performed hyperbaric oxygen therapy (HBO) combi...
Source: Japanese Dental Science Review - March 17, 2019 Category: Dentistry Source Type: research

Symposium: Imaging modalities for drug-related osteonecrosis of the jaw (6), assessment of mandibular metabolism due to long-term administration of an anti-resorptive agent by bone scintigraphy (secondary publication)
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Yumiko Ohbayashi, Fumi Nakai, Akinori Iwasaki, Takaaki Ogawa, Yuka Yamamoto, Yoshihiro Nishiyama, Minoru MiyakeSummaryIt is not yet known why anti-resorptive agent-related osteonecrosis specifically affects the jaw. Here we assessed changes in the bone metabolism of the mandible in response to long-term bisphosphonate (BP) therapy, and we compared the bone metabolism changes of the mandible with those of other bone sites using a quantitative analysis by bone scintigraphy. The region of interest was selected by identifying wi...
Source: Japanese Dental Science Review - February 16, 2019 Category: Dentistry Source Type: research

Symposium: Imaging modalities for drug-related osteonecrosis of the jaw (4), CT and MR imaging findings of antiresorptive agent-related osteonecrosis of the jaws/medication-related osteonecrosis of the jaw (secondary publication)
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Akira Baba, Hiroya Ojiri, Tazuko K. Goto, Koshi Ikeda, Hideomi Yamauchi, Nobuhiro Ogino, Takuji MogamiSummaryGenerally, CT and MR images of antiresorptive agent-related osteonecrosis of the jaw (ARONJ)/medication-related osteonecrosis of the jaw (MRONJ) show nonspecific findings as seen in active osteomyelitis.However, there are some characteristics as follows; unilateral maxillary sinusitis adjacent to ipsilateral maxillary ARONJ/MRONJ, DRONJ presenting larger sequestrum and periosteal reaction more frequently than BRONJ,...
Source: Japanese Dental Science Review - February 16, 2019 Category: Dentistry Source Type: research