Mouse bone marrow-derived endothelial progenitor cells do not restore radiation-induced microvascular damage.
Conclusion. Treatment with BM-derived EPCs did not restore radiation-induced microvascular damage but it did inhibit fibrosis. Endoglin deficiency did not impair this process.
PMID: 25101181 [PubMed] (Source: ISRN Cardiology)
Source: ISRN Cardiology - August 8, 2014 Category: Cardiology Authors: Seemann I, Te Poele JA, Hoving S, Stewart FA Tags: ISRN Cardiol Source Type: research
Open versus Endovascular Repair of Abdominal Aortic Aneurysm in the Elective and Emergent Setting in a Pooled Population of 37,781 Patients: A Systematic Review and Meta-Analysis.
Conclusions. EVAR has lower rates of 30-day mortality, 30-day MI, and LOS in both elective and ruptured AAA repair.
PMID: 25006502 [PubMed] (Source: ISRN Cardiology)
Source: ISRN Cardiology - July 10, 2014 Category: Cardiology Authors: Thomas DM, Hulten EA, Ellis ST, Anderson DM, Anderson N, McRae F, Malik JA, Villines TC, Slim AM Tags: ISRN Cardiol Source Type: research
Abdominal aortic aneurysms and coronary artery disease in a small country with high cardiovascular burden.
Conclusion. This is the largest study in our region that describes the epidemiology of AAA with concomitant CAD. As the mortality rate is quite high in this high risk population, routine screening for AAA in CAD patients and vice versa needs further studies for proper risk stratification.
PMID: 24701361 [PubMed] (Source: ISRN Cardiology)
Source: ISRN Cardiology - April 5, 2014 Category: Cardiology Authors: Al-Thani H, El-Menyar A Tags: ISRN Cardiol Source Type: research
Exclusion of left atrial appendage thrombus using single phase coronary computed tomography as compared to transesophageal echocardiography in patients undergoing pulmonary vein isolation.
Conclusion. Given the utility of a preprocedural single phase CCTA for the performance of PVI, the absence of a filling defect negates the need for a subsequent TEE as an adjunct for exclusion of LAA thrombus.
PMID: 24701362 [PubMed] (Source: ISRN Cardiology)
Source: ISRN Cardiology - April 5, 2014 Category: Cardiology Authors: Saucedo J, Martinho S, Frankel D, Slim AM, Eckart RE Tags: ISRN Cardiol Source Type: research
Myocardial injury in critically ill children: a case control study.
Conclusion. In critically ill children, cardiac troponin T levels were elevated and were associated with duration of ventilation and disease severity.
PMID: 24660069 [PubMed] (Source: ISRN Cardiology)
Source: ISRN Cardiology - March 25, 2014 Category: Cardiology Authors: Hassan B, Morsy S, Siam A, Ali AS, Abdo M, Al Shafie M, Hassaneen A Tags: ISRN Cardiol Source Type: research
Risks and Benefits of Thrombolytic, Antiplatelet, and Anticoagulant Therapies for ST Segment Elevation Myocardial Infarction: Systematic Review.
Conclusion. The increasing complexity of STEMI treatment has resulted in significant reduction in mortality along with increased rates of MB. Overall, however, the benefits of treatment outweigh the associated risks of MB.
PMID: 24653840 [PubMed - as supplied by publisher] (Source: ISRN Cardiology)
Source: ISRN Cardiology - March 22, 2014 Category: Cardiology Authors: Nascimento BR, de Sousa MR, Demarqui FN, Ribeiro AL Tags: ISRN Cardiol Source Type: research
Angiotensin Receptor Antagonists to Prevent Sudden Death in Heart Failure: Does the Dose Matter?
Abstract
International guidelines recommend ICD implantation in patients with severe left ventricular dysfunction of any origin only after careful optimization of medical therapy. Indeed, major randomized clinical trials suggest that suboptimal use of fundamental drugs, such as ACE inhibitors (ACE-i) and beta-blockers, may affect ICD shock-free survival, sudden cardiac death (SCD), and overall mortality. While solid evidence in favour of pharmacological therapy based on ACE-i with or without beta-blockers is available, data on SCD in HF patients treated with angiotensin receptor blockers (ARBs) are limited...
Source: ISRN Cardiology - March 22, 2014 Category: Cardiology Authors: Francia P, Palano F, Tocci G, Adduci C, Ricotta A, Semprini L, Caprinozzi M, Balla C, Volpe M Tags: ISRN Cardiol Source Type: research
Mitochondrial morphofunctional alterations in smooth muscle cells of aorta in rats.
Abstract
In an experimental model of atherogenesis induced by hyperfibrinogenemia (HF), the pharmacological response of vitamin E was studied in order to assess its antioxidant effect on the mitochondrial morphofunctional alterations in aortic smooth muscle cells. Three groups of male rats were used: (Ctr) control, (AI) atherogenesis induced for 120 days, and (AIE) atherogenesis induced for 120 days and treated with vitamin E. HF was induced by adrenalin injection (0.1 mg/day/rat) for 120 days. AIE group was treated with the administration of 3.42 mg/day/rat of vitamin E for 105 days after the first in...
Source: ISRN Cardiology - March 22, 2014 Category: Cardiology Authors: Baez Mdel C, Tarán M, Llorens C, Balceda A, Scribano Mde L, Pons P, Moya M Tags: ISRN Cardiol Source Type: research
Evaluation of the Pericardium with CT and MR.
Abstract
The pericardium plays an important role in optimizing cardiac motion and chamber pressures and serves as a barrier to pathology. In addition to pericardial anatomy and function, this review article covers a variety of pericardial conditions, with mention of potential pitfalls encountered during interpretation of diagnostic imaging. Normal and abnormal appearance of pericardium on CT and MR imaging is emphasized, including dynamic imaging correlates of pericardial pathophysiology.
PMID: 24616819 [PubMed - as supplied by publisher] (Source: ISRN Cardiology)
Source: ISRN Cardiology - March 13, 2014 Category: Cardiology Authors: Czum JM, Silas AM, Althoen MC Tags: ISRN Cardiol Source Type: research
Doxapram hydrochloride aggravates adrenaline-induced arrhythmias accompanied by bidirectional ventricular tachycardia.
Conclusion. Drug-induced impairment of intracellular Ca(2+) regulation caused BVT in the absence of genetic abnormalities in proteins in the sarcoplasmic reticulum.
PMID: 24527224 [PubMed] (Source: ISRN Cardiology)
Source: ISRN Cardiology - February 15, 2014 Category: Cardiology Authors: Oikawa S, Nomura H, Nishio M, Nagata R, Hata T Tags: ISRN Cardiol Source Type: research
Risk factors for asymptomatic ventricular dysfunction in rheumatoid arthritis patients.
Conclusions. Ventricular dysfunction is common in rheumatoid arthritis and associated with longer disease duration and increased serologic markers of rheumatoid arthritis. Screening for cardiac abnormalities should be considered in this kind of patients.
PMID: 24368945 [PubMed] (Source: ISRN Cardiology)
Source: ISRN Cardiology - December 26, 2013 Category: Cardiology Authors: Garza-García C, Rocío SS, Orea-Tejeda A, Castillo-Martínez L, Eduardo C, López-Campos JL, Keirns-Davis C Tags: ISRN Cardiol Source Type: research
The Role of BNP and CRP in Predicting the Development of Atrial Fibrillation in Patients Undergoing Isolated Coronary Artery Bypass Surgery.
Conclusion. Elevated preoperative BNP serum levels are associated with the development of post-CABG AF, while CRP does not seem to be influential.
PMID: 24455301 [PubMed] (Source: ISRN Cardiology)
Source: ISRN Cardiology - December 25, 2013 Category: Cardiology Authors: Pilatis ND, Anyfantakis ZA, Spiliopoulos K, Degiannis D, Chaidaroglou A, Vergou G, Kimpouri K, Cokkinos DV Tags: ISRN Cardiol Source Type: research
Hybrid Surgical and Catheter Treatment for Atrial Fibrillation.
Abstract
Advances in surgery for atrial fibrillation from cut and sew technique to thoracoscopy and new energy source have enabled minimally invasive approach which avoids median sternotomy and cardiopulmonary bypass. However, minimally invasive approach is unable to match the outcome of classic surgical technique due to difficulty in creating some of linear ablation lines. Hybrid procedure using catheter mapping and ablation in addition to minimally invasive surgical ablation has gained interest to combine the advantages of both procedures. No large study has been conducted to date comparing this new tech...
Source: ISRN Cardiology - December 16, 2013 Category: Cardiology Authors: Kaneko T, Aranki SF Tags: ISRN Cardiol Source Type: research
Retracted: Intracoronary Adenosine versus Intravenous Adenosine during Primary PCI for ST-Elevation Myocardial Infarction: Which One Offers Better Outcomes in terms of Microvascular Obstruction?
PMID: 24455302 [PubMed] (Source: ISRN Cardiology)
Source: ISRN Cardiology - December 14, 2013 Category: Cardiology Authors: Isrn Cardiology Tags: ISRN Cardiol Source Type: research
Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin-Receptor Blockers (ARBs) in Patients at High Risk of Cardiovascular Events: A Meta-Analysis of 10 Randomised Placebo-Controlled Trials.
Conclusion. ACEI treatment reduced stroke, nonfatal MI, cardiovascular and total mortality in high risk patients, while ARB modestly reduced stroke with no effect on nonfatal MI, cardiovascular and total mortality.
PMID: 24307952 [PubMed - as supplied by publisher] (Source: ISRN Cardiology)
Source: ISRN Cardiology - December 7, 2013 Category: Cardiology Authors: Ong HT, Ong LM, Ho JJ Tags: ISRN Cardiol Source Type: research
