Pressure ulcers in trauma patients with suspected spine injury: a prospective cohort study with emphasis on device‐related pressure ulcers
Abstract Of all patients in a hospital environment, trauma patients may be particularly at risk for developing (device‐related) pressure ulcers (PUs), because of their traumatic injuries, immobility, and exposure to immobilizing and medical devices. Studies on device‐related PUs are scarce. With this study, the incidence and characteristics of PUs and the proportion of PUs that are related to devices in adult trauma patients with suspected spinal injury were described. From January–December 2013, 254 trauma patients were visited every 2 days for skin assessment. The overall incidence of PUs was 28·3% (n = ...
Source: International Wound Journal - January 15, 2016 Category: Surgery Authors: Wietske HW Ham, Lisette Schoonhoven, Marieke J Schuurmans, Luke PH Leenen Tags: ORIGINAL ARTICLE Source Type: research

An apparently untreatable ulcer of the face
(Source: International Wound Journal)
Source: International Wound Journal - January 14, 2016 Category: Surgery Authors: Alessandro Borghi, Sergio Gianesini, Massimo Pedriali, Antonio Stefanelli, Giovanni Mangiola, Patrizia Dalla Caneva, Giovanni Lanza, Annarosa Virgili, Paolo Zamboni Tags: LETTER TO THE EDITOR Source Type: research

The ability of quaternary ammonium groups attached to a urethane bandage to inhibit bacterial attachment and biofilm formation in a mouse wound model
This study examines the effectiveness of a polyurethane foam wound dressing bound with polydiallyl‐dimethylammonium chloride (pDADMAC) to inhibit the growth of bacteria in a wound on the back of a mouse. This technology does not allow pDADMAC to leach away from the dressing into the wound, thereby preventing cytotoxic effects. Staphylococcus aureus, Pseudomonas aeruginosa and Acinetobacter baumannii were chosen for the study to infect the wounds. S. aureus and P. aeruginosa are important pathogens in wound infections, while A. baumannii was selected because of its ability to acquire or upregulate antibiotic drug resistan...
Source: International Wound Journal - January 10, 2016 Category: Surgery Authors: Phat L Tran, Eric Huynh, Abdul N Hamood, Anselm de Souza, Gregory Schultz, Bernd Liesenfeld, Dilip Mehta, Daniel Webster, Ted W Reid Tags: ORIGINAL ARTICLE Source Type: research

Calendar
(Source: International Wound Journal)
Source: International Wound Journal - January 5, 2016 Category: Surgery Tags: CALENDAR OF EVENTS Source Type: research

News and Views
(Source: International Wound Journal)
Source: International Wound Journal - January 5, 2016 Category: Surgery Tags: NEWS Source Type: research

Society News
(Source: International Wound Journal)
Source: International Wound Journal - January 5, 2016 Category: Surgery Tags: NEWS Source Type: research

A New International Wound Diagnostic Community
(Source: International Wound Journal)
Source: International Wound Journal - January 5, 2016 Category: Surgery Authors: Douglas Queen Tags: EDITORIAL Source Type: research

Issue Information – TOC
(Source: International Wound Journal)
Source: International Wound Journal - January 5, 2016 Category: Surgery Tags: ISSUE INFORMATION Source Type: research

Issue Information – Aims and Scope
(Source: International Wound Journal)
Source: International Wound Journal - January 5, 2016 Category: Surgery Tags: ISSUE INFORMATION Source Type: research

Issue Information – JIP
(Source: International Wound Journal)
Source: International Wound Journal - January 5, 2016 Category: Surgery Tags: ISSUE INFORMATION Source Type: research

High inspired oxygen versus low inspired oxygen for reducing surgical site infection: a meta‐analysis
Abstract To perform a meta‐analysis of published literature to assess the role of high‐concentration inspired oxygen in reducing the incidence of surgical site infections (SSIs) following all types of surgery, a comprehensive search for published randomized controlled trials (RCTs) comparing high‐ with low‐concentration inspired oxygen for SSIs was performed. The related data were extracted by two independent authors. The fixed and random effects methods were used to combine data. Twelve RCTs involving 6750 patients were included. Our pooled result found that no significant difference in the incidence of SSIs was o...
Source: International Wound Journal - December 23, 2015 Category: Surgery Authors: Hongye Wang, Shukun Hong, Yuanyuan Liu, Yan Duan, Hongmei Yin Tags: ORIGINAL ARTICLE Source Type: research

High inspired oxygen versus low inspired oxygen for reducing surgical site infection: a meta ‐analysis
Abstract To perform a meta‐analysis of published literature to assess the role of high‐concentration inspired oxygen in reducing the incidence of surgical site infections (SSIs) following all types of surgery, a comprehensive search for published randomized controlled trials (RCTs) comparing high‐ with low‐concentration inspired oxygen for SSIs was performed. The related data were extracted by two independent authors. The fixed and random effects methods were used to combine data. Twelve RCTs involving 6750 patients were included. Our pooled result found that no significant difference in the incidence of SSIs was o...
Source: International Wound Journal - December 22, 2015 Category: Surgery Authors: Hongye Wang, Shukun Hong, Yuanyuan Liu, Yan Duan, Hongmei Yin Tags: ORIGINAL ARTICLE Source Type: research

The development and testing of a skin tear risk assessment tool
Abstract The aim of the present study is to develop a reliable and valid skin tear risk assessment tool. The six characteristics identified in a previous case control study as constituting the best risk model for skin tear development were used to construct a risk assessment tool. The ability of the tool to predict skin tear development was then tested in a prospective study. Between August 2012 and September 2013, 1466 tertiary hospital patients were assessed at admission and followed up for 10 days to see if they developed a skin tear. The predictive validity of the tool was assessed using receiver operating characterist...
Source: International Wound Journal - December 22, 2015 Category: Surgery Authors: Nelly Newall, Gill F Lewin, Max K Bulsara, Keryln J Carville, Gavin D Leslie, Pam A Roberts Tags: ORIGINAL ARTICLE Source Type: research

Reactive oxygen species (ROS) and wound healing: the functional role of ROS and emerging ROS‐modulating technologies for augmentation of the healing process
This article presents a review of the evidence supporting the critical role of ROS in wound healing and infection control at the wound site, and some of the new emerging concepts associated with ROS modulation and its potential in improving wound healing are discussed. (Source: International Wound Journal)
Source: International Wound Journal - December 21, 2015 Category: Surgery Authors: Christopher Dunnill, Thomas Patton, James Brennan, John Barrett, Matthew Dryden, Jonathan Cooke, David Leaper, Nikolaos T Georgopoulos Tags: ORIGINAL ARTICLE Source Type: research

Reactive oxygen species (ROS) and wound healing: the functional role of ROS and emerging ROS ‐modulating technologies for augmentation of the healing process
This article presents a review of the evidence supporting the critical role of ROS in wound healing and infection control at the wound site, and some of the new emerging concepts associated with ROS modulation and its potential in improving wound healing are discussed. (Source: International Wound Journal)
Source: International Wound Journal - December 20, 2015 Category: Surgery Authors: Christopher Dunnill, Thomas Patton, James Brennan, John Barrett, Matthew Dryden, Jonathan Cooke, David Leaper, Nikolaos T Georgopoulos Tags: ORIGINAL ARTICLE Source Type: research

Inhibition of cyclooxygenase‐1 and ‐2 activity in keratinocytes inhibits PGE2 formation and impairs vascular endothelial growth factor release and neovascularisation in skin wounds
This study investigated the role of Cox activity in the regulation of vascular endothelial growth factor (VEGF) expression in keratinocytes and the formation of new blood vessels in acute wounds in mice. To this end, human HaCaT keratinocytes were stimulated with epidermal growth factor (EGF). EGF increased Cox‐1 mRNA in the presence of the constitutively expressed Cox‐1 protein in keratinocytes. EGF coinduced Cox‐2 and VEGF165 mRNA and protein expression and an accumulation of prostaglandin E2 (PGE2) in cell culture supernatants. Inhibition of Cox isozyme activity by Cox‐1 and ‐2 siRNA or ibuprofen reduced PGE2 ...
Source: International Wound Journal - December 17, 2015 Category: Surgery Authors: Itamar Goren, Seo‐Youn Lee, Damian Maucher, Rolf Nüsing, Thomas Schlich, Josef Pfeilschifter, Stefan Frank Tags: ORIGINAL ARTICLE Source Type: research

Inhibition of cyclooxygenase ‐1 and ‐2 activity in keratinocytes inhibits PGE2 formation and impairs vascular endothelial growth factor release and neovascularisation in skin wounds
This study investigated the role of Cox activity in the regulation of vascular endothelial growth factor (VEGF) expression in keratinocytes and the formation of new blood vessels in acute wounds in mice. To this end, human HaCaT keratinocytes were stimulated with epidermal growth factor (EGF). EGF increased Cox‐1 mRNA in the presence of the constitutively expressed Cox‐1 protein in keratinocytes. EGF coinduced Cox‐2 and VEGF165 mRNA and protein expression and an accumulation of prostaglandin E2 (PGE2) in cell culture supernatants. Inhibition of Cox isozyme activity by Cox‐1 and ‐2 siRNA or ibuprofen reduced PGE2 ...
Source: International Wound Journal - December 16, 2015 Category: Surgery Authors: Itamar Goren, Seo ‐Youn Lee, Damian Maucher, Rolf Nüsing, Thomas Schlich, Josef Pfeilschifter, Stefan Frank Tags: ORIGINAL ARTICLE Source Type: research

Self ‐treatment of foot ulcers as a risk factor for delayed diagnosis of acral melanoma
(Source: International Wound Journal)
Source: International Wound Journal - December 16, 2015 Category: Surgery Authors: Ali Memis, Sinan Ozturk, Mesut Mutluoglu, Huseyin Karagoz, Hakan Ay Tags: LETTER TO THE EDITOR Source Type: research

A haemostatic technique using silicone gel dressing for burn surgery
This study was a retrospective observational study. From 1 April 2011 to 31 March 2015, we collated data including pre‐ and 24‐hour postoperative haemoglobin levels from patients over 15 years of age who underwent tangential excision for burn injuries. We also collected data on the amounts of measured blood loss, blood transfusions, excised areas, harvest areas and duration of surgeries. The collected data were divided into a conventional group and a silicone gel dressing group. Then, we analysed the differences between the two groups. During the study period, 357 patients were admitted to our burn centre, and 60 opera...
Source: International Wound Journal - December 15, 2015 Category: Surgery Authors: Akinori Osuka, Yuichi Kuroki, Masashi Ueyama Tags: ORIGINAL ARTICLE Source Type: research

Prevalence of HIV infection among burn patients: is there a relationship with patients' outcomes?
Abstract The aim of the present study was to determine the prevalence of human immunodeficiency virus (HIV) infection among acute burn patients and its impacts on patient's outcomes in an Iranian burn care hospital. A cross‐sectional study was conducted in a tertiary burn care hospital in Iran, retrospectively reviewing the data records of all patients admitted between February 2011 and February 2012. The HIV status of all the patients was assessed in relation to clinical outcomes and the patient's prognosis. A total of 969 patients were included in this study. Five patients (0·5%) were HIV positive, and all of th...
Source: International Wound Journal - December 15, 2015 Category: Surgery Authors: Seyed Hamid Salehi, Kamran As'adi, Seyedeh Azam Tabatabaeenezhad, Mohammad Naderan, Saeed Shoar Tags: ORIGINAL ARTICLE Source Type: research

The role of negative pressure wound therapy in the management of hidradenitis suppurativa: a case report and literature review
Abstract Hidradenitis suppurativa (HS), also known as acne inversa, is a chronic, recurrent inflammatory disease affecting skin that bears apocrine glands. It is characterised by the presence of tender subcutaneous nodules that may rupture, resulting in deep dermal abscesses, fibrosis with dermal contractures and induration of the skin. The management of HS is a challenge for physicians as the pathogenesis is not clearly defined and prevents the use and development of directed therapies. Treatment options are oral agents (antibiotics, immunomodulators) and surgical excision. Historically, surgical management has been compl...
Source: International Wound Journal - December 13, 2015 Category: Surgery Authors: Raphael Parrado, Manuel Cadena, Arturo Vergara, Diana Cadena, Juan G Chalela Tags: ORIGINAL ARTICLE Source Type: research

Comment on ‘Basic concepts regarding fractures healing and the current options and future directions in managing bone fractures’
(Source: International Wound Journal)
Source: International Wound Journal - December 12, 2015 Category: Surgery Authors: Annika Weigand, Raymund E Horch, Justus P Beier, Andreas Arkudas, Anja M Boos Tags: LETTER TO THE EDITOR Source Type: research

Cross ‐sectional correlations between the toe brachial index and lower limb complications in older people
Abstract The aim of the study was to investigate the relationship between the toe brachial index (TBI) and foot ulceration and amputation in older people. Two hundred and sixty‐one participants meeting guidelines for lower limb vascular assessment had their toe and brachial blood pressure measured, medical records audited and signs and symptoms of peripheral arterial disease (PAD) recorded. Pearson's correlation and linear regression analyses were performed to determine the strength of relationships between variables. Significant correlations were found between the TBI and painful symptoms (r = −0·35, P
Source: International Wound Journal - December 8, 2015 Category: Surgery Authors: Jennifer A Sonter, Vivienne H Chuter Tags: ORIGINAL ARTICLE Source Type: research

Improved wound management at lower cost: a sensible goal for Australia
Abstract Chronic wounds cost the Australian health system at least US$2·85 billion per year. Wound care services in Australia involve a complex mix of treatment options, health care sectors and funding mechanisms. It is clear that implementation of evidence‐based wound care coincides with large health improvements and cost savings, yet the majority of Australians with chronic wounds do not receive evidence‐based treatment. High initial treatment costs, inadequate reimbursement, poor financial incentives to invest in optimal care and limitations in clinical skills are major barriers to the adoption of evidence‐...
Source: International Wound Journal - December 3, 2015 Category: Surgery Authors: Rosana E Norman, Michelle Gibb, Anthony Dyer, Jennifer Prentice, Stephen Yelland, Qinglu Cheng, Peter A Lazzarini, Keryln Carville, Karen Innes‐Walker, Kathleen Finlayson, Helen Edwards, Edward Burn, Nicholas Graves Tags: INVITED REVIEW Source Type: research

Mesenchymal stem cell‐conditioned medium accelerates wound healing with fewer scars
Abstract Mesenchymal stem cells (MSCs) derived from umbilical cords (UC‐MSCs) have been shown to enhance cutaneous wound healing by means of the paracrine activity. Fibroblasts are the primary cells involved in wound repair. The paracrine effects of UC‐MSCs on dermal fibroblasts have not been fully explored in vitro or in vivo. Dermal fibroblasts were treated with conditioned media from UC‐MSCs (UC‐MSC‐CM). In this model, UC‐MSC‐CM increased the proliferation and migration of dermal fibroblasts. Moreover, adult dermal fibroblasts transitioned into a phenotype with a low myofibroblast formation capacity, a dec...
Source: International Wound Journal - December 3, 2015 Category: Surgery Authors: Meirong Li, Fuxin Luan, Yali Zhao, Haojie Hao, Jiejie Liu, Liang Dong, Xiaobing Fu, Weidong Han Tags: ORIGINAL ARTICLE Source Type: research

Mesenchymal stem cell ‐conditioned medium accelerates wound healing with fewer scars
Abstract Mesenchymal stem cells (MSCs) derived from umbilical cords (UC‐MSCs) have been shown to enhance cutaneous wound healing by means of the paracrine activity. Fibroblasts are the primary cells involved in wound repair. The paracrine effects of UC‐MSCs on dermal fibroblasts have not been fully explored in vitro or in vivo. Dermal fibroblasts were treated with conditioned media from UC‐MSCs (UC‐MSC‐CM). In this model, UC‐MSC‐CM increased the proliferation and migration of dermal fibroblasts. Moreover, adult dermal fibroblasts transitioned into a phenotype with a low myofibroblast formation capacity, a dec...
Source: International Wound Journal - December 2, 2015 Category: Surgery Authors: Meirong Li, Fuxin Luan, Yali Zhao, Haojie Hao, Jiejie Liu, Liang Dong, Xiaobing Fu, Weidong Han Tags: ORIGINAL ARTICLE Source Type: research

Treatment of chronic diabetic lower extremity ulcers with advanced therapies: a prospective, randomised, controlled, multi‐centre comparative study examining clinical efficacy and cost
Abstract Advanced therapies such as bioengineered skin substitutes (BSS) and dehydrated human amnion/chorion membrane (dHACM) have been shown to promote healing of chronic diabetic ulcers. An interim analysis of data from 60 patients enrolled in a prospective, randomised, controlled, parallel group, multi‐centre clinical trial showed that dHACM (EpiFix®, MiMedx Group Inc., Marietta, GA) is superior to standard wound care (SWC) and BSS (Apligraf®, Organogenesis, Inc., Canton, MA) in achieving complete wound closure within 4–6 weeks. Rates and time to closure at a longer time interval and factors influencing ...
Source: International Wound Journal - December 1, 2015 Category: Surgery Authors: Charles M Zelen, Thomas E Serena, Lisa Gould, Lam Le, Marissa J Carter, Jennifer Keller, William W Li Tags: ORIGINAL ARTICLE Source Type: research

Cement burn: an occupational disease with favorable outcome. Case report
We present the case of a 54‐year‐old patient with a thermal cement burn. This rare case is a localised occupational chemical cement burn on the lower limbs, with no systemic involvement and favourable outcome. The lesion was induced by prolonged contact of the skin with cement and water during hot summer days. (Source: International Wound Journal)
Source: International Wound Journal - December 1, 2015 Category: Surgery Authors: Anca Chiriac, Cristian Podoleanu, Cosmin Moldovan, Simona Stolnicu Tags: CASE REPORT Source Type: research

Porcine acellular dermal matrix (PADM) vascularises after exposure in open necrotic wounds seen after complex hernia repair
Abstract Biological alternatives to synthetic meshes are increasingly utilised in complex abdominal wall reconstruction. There is a lack of evidence demonstrating that non‐cross‐linked porcine acellular dermal matrix vascularizes and integrates with human tissue in suboptimal wound conditions. We aimed to evaluate these properties in Strattice™ (Life Cell Inc., Branchburg, NJ) following ventral hernia repair. A retrospective review of patients with high‐risk ventral hernia repair utilising Strattice™ as an onlay after open component separation was conducted. Patients with postoperative wound exploration a...
Source: International Wound Journal - December 1, 2015 Category: Surgery Authors: Arvind U Gowda, Sarah M. Chang, Karan Chopra, Jamil A Matthews, Jennifer Sabino, Jeffrey A Stromberg, Hamid R Zahiri, Joel Pinczewski, Luther H Holton, Ronald P Silverman, Devinder P Singh Tags: ORIGINAL ARTICLE Source Type: research

Self‐treatment of foot ulcers as a risk factor for delayed diagnosis of acral melanoma
(Source: International Wound Journal)
Source: International Wound Journal - December 1, 2015 Category: Surgery Authors: Ali Memis, Sinan Ozturk, Mesut Mutluoglu, Huseyin Karagoz, Hakan Ay Tags: LETTER TO THE EDITOR Source Type: research

Burn wound cooling with tap water: is it safe in developing countries or not?
(Source: International Wound Journal)
Source: International Wound Journal - December 1, 2015 Category: Surgery Authors: Sinan Ozturk, Mesut Mutluoglu Tags: LETTER TO THE EDITOR Source Type: research

Comment on ‘Basic concepts regarding fractures healing and the current options and future directions in managing bone fractures’
(Source: International Wound Journal)
Source: International Wound Journal - December 1, 2015 Category: Surgery Authors: Annika Weigand, Raymund E Horch, Justus P Beier, Andreas Arkudas, Anja M Boos Tags: LETTER TO THE EDITOR Source Type: research

Cross‐sectional correlations between the toe brachial index and lower limb complications in older people
Abstract The aim of the study was to investigate the relationship between the toe brachial index (TBI) and foot ulceration and amputation in older people. Two hundred and sixty‐one participants meeting guidelines for lower limb vascular assessment had their toe and brachial blood pressure measured, medical records audited and signs and symptoms of peripheral arterial disease (PAD) recorded. Pearson's correlation and linear regression analyses were performed to determine the strength of relationships between variables. Significant correlations were found between the TBI and painful symptoms (r = −0·35, P
Source: International Wound Journal - December 1, 2015 Category: Surgery Authors: Jennifer A Sonter, Vivienne H Chuter Tags: ORIGINAL ARTICLE Source Type: research

The value of inflammatory markers to diagnose and monitor diabetic foot osteomyelitis
In this study, we assessed the effectiveness of inflammatory markers to diagnose and monitor the treatment of osteomyelitis in the diabetic foot. We evaluated 35 consecutive patients admitted to our hospital with infected foot ulcers. Patients were divided in two groups based on the results of bone culture and histopathology: osteomyelitis and no osteomyelitis. The erythrocyte sedimentation rate (ESR), C‐reactive protein (CRP), procalcitonin (PCT), interleukin‐6 (IL‐6), interleukin‐8 (IL‐8), tumor necrosis factor alpha (TNFα), monocyte chemotactic protein‐1 (MCP‐1) and macrophage inflammatory protein‐...
Source: International Wound Journal - December 1, 2015 Category: Surgery Authors: Suzanne AV Asten, Adam Nichols, Javier Fontaine, Kavita Bhavan, Edgar JG Peters, Lawrence A Lavery Tags: ORIGINAL ARTICLE Source Type: research

Successful eradication of helical rim keloids with surgical excision followed by pressure therapy using a combination of magnets and silicone gel sheeting
Abstract Extremely limited data are available for the treatment of helical rim keloids. The purpose of the present study was to demonstrate the successful treatment of helical rim keloids using surgical exicison followed by a newly designed pressure therapy device. We treated 40 pure helical rim keloids in 36 patients with surgical excisions followed by pressure therapy using a combination of magnets and silicone gel sheeting for 12 hours over a period of 2 years, from May 2012 to February 2014, at tertiary medical centre. The follow‐up period was 18 months. Primary outcome was recurrence of keloids. Secondary outcome wa...
Source: International Wound Journal - November 24, 2015 Category: Surgery Authors: Tae Hwan Park, Dong Kyun Rah Tags: ORIGINAL ARTICLE Source Type: research

Exploration of pressure ulcer and related skin problems across the spectrum of health care settings in Ontario using administrative data
Abstract This is a prospective cohort study using population‐level administrative data to describe the scope of pressure ulcers in terms of its prevalence, incidence risk, associating factors and the extent to which best practices were applied across a spectrum of health care settings. The data for this study includes the information of Ontario residents who were admitted to acute care, home care, long term care or continuing care and whose health care data is contained in the resident assessment instrument‐minimum data set (RAI‐MDS) and the health outcomes for better information and care (HOBIC) database from 2010 t...
Source: International Wound Journal - November 21, 2015 Category: Surgery Authors: Kevin Y Woo, Kim Sears, Joan Almost, Rosemary Wilson, Marlo Whitehead, Elizabeth G VanDenKerkhof Tags: ORIGINAL ARTICLE Source Type: research

Exploration of pressure ulcer and related skin problems across the spectrum of health care settings in Ontario using administrative data
Abstract This is a prospective cohort study using population‐level administrative data to describe the scope of pressure ulcers in terms of its prevalence, incidence risk, associating factors and the extent to which best practices were applied across a spectrum of health care settings. The data for this study includes the information of Ontario residents who were admitted to acute care, home care, long term care or continuing care and whose health care data is contained in the resident assessment instrument‐minimum data set (RAI‐MDS) and the health outcomes for better information and care (HOBIC) database from 2010 t...
Source: International Wound Journal - November 19, 2015 Category: Surgery Authors: Kevin Y Woo, Kim Sears, Joan Almost, Rosemary Wilson, Marlo Whitehead, Elizabeth G VanDenKerkhof Tags: ORIGINAL ARTICLE Source Type: research

A wearable wound moisture sensor as an indicator for wound dressing change: an observational study of wound moisture and status
This study tests the moisture content of wounds in normal practice in order to observe the moisture condition of the wound at the point of dressing change. This study is also the first large‐scale observational study that investigates wound moisture status at dressing change. The WoundSense sensor is a commercially available moisture sensor which sits directly on the wound in order to find the moisture status of the wound without disturbing or removing the dressing. The results show that of the 588 dressing changes recorded, 44·9% were made when the moisture reading was in the optimum moisture zone. Of the 30 pati...
Source: International Wound Journal - November 13, 2015 Category: Surgery Authors: Stephen D Milne, Ihab Seoudi, Hanadi Al Hamad, Talal K Talal, Anzila A Anoop, Niloofar Allahverdi, Zain Zakaria, Robert Menzies, Patricia Connolly Tags: ORIGINAL ARTICLE Source Type: research

Pilot study to evaluate a novel three‐dimensional wound measurement device
This study aims to determine the accuracy of a new three‐dimensional wound measurement (3DWM) device against laser‐assisted wound measurement (LAWM) devices and traditional methods of wound measurement. Using several wound models, we demonstrate that the 3DWM device measures wound area, depth and volume similarly to the other methods tested. This is especially apparent when changes in wound measurements were compared between the two devices. Differences between the two technologies were apparent when analysing wound measurement time and measurement repeatability. There was a significantly lower incidence of error in me...
Source: International Wound Journal - November 11, 2015 Category: Surgery Authors: Jessica D Bills, Sandra J Berriman, Debby L Noble, Lawrence A Lavery, Kathryn E Davis Tags: ORIGINAL ARTICLE Source Type: research

ActicoatTM stimulates inflammation, but does not delay healing, in acute full‐thickness excisional wounds
Abstract ActicoatTM has antimicrobial and anti‐inflammatory effects which aid wound healing. However, in vitro studies indicate that Acticoat™ is cytotoxic and clinical and in vivo studies suggest that it may delay healing in acute wounds. Therefore, this study investigated the effects of Acticoat™ on healing in acute full‐thickness excisional wounds. Using a porcine model, healing was assessed on days 3, 6, 9 and 15 post‐wounding. Five wounds dressed with Acticoat™ and five wounds dressed with polyurethane film (control) were assessed per day (n = 40 wounds). The rate of healing, infl...
Source: International Wound Journal - November 11, 2015 Category: Surgery Authors: Carol A Hartmann, Heinz Rode, Beverley Kramer Tags: ORIGINAL ARTICLE Source Type: research

Pilot study to evaluate a novel three ‐dimensional wound measurement device
This study aims to determine the accuracy of a new three‐dimensional wound measurement (3DWM) device against laser‐assisted wound measurement (LAWM) devices and traditional methods of wound measurement. Using several wound models, we demonstrate that the 3DWM device measures wound area, depth and volume similarly to the other methods tested. This is especially apparent when changes in wound measurements were compared between the two devices. Differences between the two technologies were apparent when analysing wound measurement time and measurement repeatability. There was a significantly lower incidence of error in me...
Source: International Wound Journal - November 10, 2015 Category: Surgery Authors: Jessica D Bills, Sandra J Berriman, Debby L Noble, Lawrence A Lavery, Kathryn E Davis Tags: ORIGINAL ARTICLE Source Type: research

Acticoat ™ stimulates inflammation, but does not delay healing, in acute full‐thickness excisional wounds
Abstract Acticoat™ has antimicrobial and anti‐inflammatory effects which aid wound healing. However, in vitro studies indicate that Acticoat™ is cytotoxic and clinical and in vivo studies suggest that it may delay healing in acute wounds. Therefore, this study investigated the effects of Acticoat™ on healing in acute full‐thickness excisional wounds. Using a porcine model, healing was assessed on days 3, 6, 9 and 15 post‐wounding. Five wounds dressed with Acticoat™ and five wounds dressed with polyurethane film (control) were assessed per day (n = 40 wounds). The rate of healing, inflammatory ...
Source: International Wound Journal - November 10, 2015 Category: Surgery Authors: Carol A Hartmann, Heinz Rode, Beverley Kramer Tags: ORIGINAL ARTICLE Source Type: research

PredyCLU: a prediction system for chronic leg ulcers based on fuzzy logic; part I – exploring the venous side
In this study, we have elaborated a computerised prediction system for chronic leg ulcers (PredyCLU) based on fuzzy logic, which was retrospectively applied on a multicentre population of 77 patients with CVD. This evaluation system produced reliable risk score patterns and served effectively as a stratification risk tool in patients with CVD who were at the risk of developing CVUs. (Source: International Wound Journal)
Source: International Wound Journal - November 6, 2015 Category: Surgery Authors: Stefano de Franciscis, Salvatore Fregola, Alessandro Gallo, Giuseppe Argirò, Andrea Barbetta, Gianluca Buffone, Francesco G Caliò, Giovanni De Caridi, Bruno Amato, Raffaele Serra Tags: ORIGINAL ARTICLE Source Type: research

A treatment algorithm to identify therapeutic approaches for leg ulcers in patients with sickle cell disease
Abstract Sickle cell leg ulcers (SCLUs) are a common complication of sickle cell disease (SCD). Patients who develop ulcers appear to have a more severe haemolysis‐associated vasculopathy than individuals who do not develop them, and manifest other complications such as priapism and pulmonary hypertension. SCLUs are slow to heal and often recur, affecting both the emotional and physical well‐being of patients. Here we summarise what is known about the pathophysiology of SCLUs, describe available treatment options and propose a treatment algorithm. (Source: International Wound Journal)
Source: International Wound Journal - November 4, 2015 Category: Surgery Authors: Igor A Altman, Raymond E Kleinfelder, John G Quigley, William J Ennis, Caterina P Minniti Tags: ORIGINAL ARTICLE Source Type: research

Calendar
(Source: International Wound Journal)
Source: International Wound Journal - November 3, 2015 Category: Surgery Tags: CALENDAR OF EVENTS Source Type: research

News and views
(Source: International Wound Journal)
Source: International Wound Journal - November 3, 2015 Category: Surgery Tags: NEWS Source Type: research

Are we any further forward with wound care as a clinical specialty?
(Source: International Wound Journal)
Source: International Wound Journal - November 3, 2015 Category: Surgery Authors: Keith Harding, Douglas Queen Tags: EDITORIAL Source Type: research

Clinico ‐microbiological study of Pseudomonas aeruginosa in wound infections and the detection of metallo‐β‐lactamase production
Abstract Pseudomonas aeruginosa is a common opportunistic pathogen of humans among the Gram‐negative bacilli. Clinically, it is associated with nosocomial infections like burns and surgical‐site wound infections and remains a major health concern, especially among critically ill and immunocompromised patients. This is a prospective laboratory‐based 2 year study conducted to isolate P. aeruginosa from wound specimens and the antimicrobial susceptibility pattern with reference to metallo‐β‐lactamase (MBL) production. Two hundred and twenty‐four samples of P. aeruginosa isolated from wound specimens were incl...
Source: International Wound Journal - October 29, 2015 Category: Surgery Authors: Divya Bangera, Suchitra M Shenoy, Dominic RM Saldanha Tags: ORIGINAL ARTICLE Source Type: research

Iatrogenic pressure sores: primum non nocere
(Source: International Wound Journal)
Source: International Wound Journal - October 29, 2015 Category: Surgery Authors: Billur Sezgin, Hakan Bulam, Bora Ozel Tags: LETTER TO THE EDITOR Source Type: research

The role of procalcitonin as a marker of diabetic foot ulcer infection
Abstract Foot ulcers are frequent in diabetic patients and are responsible for 85% of amputations, especially in the presence of infection. The diagnosis of diabetic foot ulcer infection is essentially based on clinical evaluation, but laboratory parameters such as erythrocyte sedimentation rate (ESR), white blood count (WBC), C‐reactive protein (CRP) and, more recently, procalcitonin (PCT) could aid the diagnosis, especially when clinical signs are misleading. Fifteen diabetic patients with infected foot ulcers were admitted to our department and were compared with an additional group of patients with non‐infected dia...
Source: International Wound Journal - October 28, 2015 Category: Surgery Authors: Mafalda Massara, Giovanni Caridi, Raffaele Serra, David Barillà, Andrea Cutrupi, Alberto Volpe, Francesco Cutrupi, Antonino Alberti, Pietro Volpe Tags: ORIGINAL ARTICLE Source Type: research