May –Thurner syndrome: an often overlooked cause for refractory venous leg ulcers
We report a 53‐year‐old female patient presenting with a refractory venous leg ulcer and unremarkable findings in the conventional ultrasonography of the leg veins. Further comprehensive diagnostics demonstrated an underlying May–Thurner syndrome. After resolution of the primary mechanical obstruction, rapid wound healing in the following 3 weeks was documented. Iliac vein compression syndrome, commonly known as May–Thurner syndrome, is a distinguishable anatomical variant that results from an external compression over the left iliac vein exerted by the overriding adjacent right common iliac artery. It is m...
Source: International Wound Journal - February 28, 2017 Category: Surgery Authors: Maryam Alkhater, Finja Jockenh öfer, Ingo Stoffels, Joachim Dissemond Tags: CASE REPORT Source Type: research

Wound management of ulcerated haemangioma of infancy  – an audit
Abstract Haemangioma of infancy, a benign tumour of blood vessels, is the most common tumour of infancy. Ulceration, the most common complication, presents a unique wound care challenge. A retrospective audit of medical records of children with haemangioma of infancy who presented to the Royal Children's Hospital, Melbourne, Australia, between January 2000 and December 2014 was undertaken with an aim to examine wound management of ulcerated haemangioma of infancy. In total, 535 hospital medical records were identified as suitable, of which 352 were randomly selected and audited, of which 84 patients had ulcerated haemangio...
Source: International Wound Journal - February 28, 2017 Category: Surgery Authors: Zerina Lokmic, Taya Grainger, Nadeeja V Atapattu, Roderic J Phillips, Anthony J Penington Tags: ORIGINAL ARTICLE Source Type: research

Improved detection of clinically relevant wound bacteria using autofluorescence image ‐guided sampling in diabetic foot ulcers
Abstract Clinical wound assessment involves microbiological swabbing of wounds to identify and quantify bacterial species, and to determine microbial susceptibility to antibiotics. The Levine swabbing technique may be suboptimal because it samples only the wound bed, missing other diagnostically relevant areas of the wound, which may contain clinically significant bacteria. Thus, there is a clinical need to improve the reliability of microbiological wound sampling. To address this, a handheld portable autofluorescence (AF) imaging device that detects bacteria in real time, without contrast agents, was developed. Here, we r...
Source: International Wound Journal - February 27, 2017 Category: Surgery Authors: Kathryn Ottolino ‐Perry, Emilie Chamma, Kristina M Blackmore, Liis Lindvere‐Teene, Danielle Starr, Kim Tapang, Cheryl F Rosen, Bethany Pitcher, Tony Panzarella, Ron Linden, Ralph S DaCosta Tags: ORIGINAL ARTICLE Source Type: research

Novel foam dressing using negative pressure wound therapy with instillation to remove thick exudate
We describe our experience with a novel foam dressing architecture in tandem with negative pressure wound therapy and instillation (NPWTi‐d) for removing viscous wound exudate and infectious materials. A retrospective review was conducted of the outcomes of 21 patients who received NPWTi‐d using a reticulated open cell foam instillation dressing with through holes (ROCF‐CC) designed to facilitate the removal of thick wound exudate and infectious materials. NPWTi‐d with ROCF‐CC was used to treat large complex chronic wounds with viscous wound exudate that contained substantial areas of devitalised tissue. Debridem...
Source: International Wound Journal - February 27, 2017 Category: Surgery Authors: Luc T éot, Florient Boissiere, Sergiu Fluieraru Tags: ORIGINAL ARTICLE Source Type: research

Systematic review and meta ‐analysis of the efficacy of epidermal grafting for wound healing
This study aims to synthesise the current evidence on EG for wound healing to establish the efficacy of this surgical technique. A comprehensive search in the MEDLINE, EMBASE and CENTRAL databases was conducted. The endpoints assessed were proportion of wounds healed and mean wound‐healing time. This systematic review was conducted and reported according to the Meta‐Analysis of Observational Studies in Epidemiology (MOOSE) guidelines. We identified 1568 articles, of which seven articles were included in this review – a total of 209 wounds in 190 patients. The mean wound duration was 17·06 weeks (95% CI 8&m...
Source: International Wound Journal - February 14, 2017 Category: Surgery Authors: Muholan Kanapathy, Oliver J Smith, Nadine Hachach ‐Haram, Nicola Bystrzonowski, Afshin Mosahebi, Toby Richards Tags: ORIGINAL ARTICLE Source Type: research

The effectiveness of negative pressure therapy on infected wounds: preliminary results
The objective of this study is to extend the indications for VAC therapy to include infected wounds by demonstrating its ability to increase the antibiotic concentration in the damaged and infected tissues. Patients who presented with ulcers infected with daptomycin‐sensitive bacteria were eligible to be enrolled in this prospective study. They were given antibiotic therapy with daptomycin with a specific protocol. A biopsy of the lesion was carried out to detect tissue concentration of the drug at time 0. Afterwards, the patients were subjected to VAC therapy. At the end of VAC therapy, a second lesion biopsy was perfor...
Source: International Wound Journal - February 14, 2017 Category: Surgery Authors: Federico Lo Torto, Marco Ruggiero, Paola Parisi, Zachary Borab, Manuel Sergi, Bruno Carlesimo Tags: ORIGINAL ARTICLE Source Type: research

Extracorporeal shockwave therapy for the treatment of chronic wound of lower extremity: current perspective and systematic review
In conclusion, this review demonstrated mild to moderate evidence to support the use of ESWT as an adjuvant therapy with a standardised wound care programme. However, it is difficult to draw firm conclusions about the efficacy of ESWT. So, future researches with high methodological quality are required to assess the efficacy and cost‐effectiveness of this relatively new physical therapy application. (Source: International Wound Journal)
Source: International Wound Journal - February 14, 2017 Category: Surgery Authors: Mohammed TA Omar, Rehab FM Gwada, Afaf AM Shaheen, Raoul Saggini Tags: ORIGINAL ARTICLE Source Type: research

Enteroatmospheric fistula management by endoscopic gastrostomy PEG tube
We describe a simple and cheap method to control fistula leakage by using a percutaneous endoscopic gastrostomy tube. (Source: International Wound Journal)
Source: International Wound Journal - February 14, 2017 Category: Surgery Authors: Luiz EC Miranda, Ana CG Miranda Tags: ORIGINAL ARTICLE Source Type: research

Quality of life and scar evolution after negative pressure or conventional therapy for wound dehiscence following post ‐bariatric abdominoplasty
No studies have examined scars and quality of life after different treatments of wound dehiscence in patients undergoing post‐bariatric abdominoplasty. Scars and quality of life of patients with postoperative wound dehiscence managed with negative pressure wound therapy (group A) and conventional wound therapy (group B) were reviewed 6 months after wound healing. Of 38 patients undergoing treatment for wound dehiscence after 203 abdominoplasty, 35 (group A = 14 versus group B = 21) entered the study. Wound healing in group A was significantly faster than group B (P = 0·001...
Source: International Wound Journal - January 31, 2017 Category: Surgery Authors: Paolo Limongelli, Giuseppina Casalino, Salvatore Tolone, Luigi Brusciano, Giovanni Docimo, Gianmattia del Genio, Ludovico Docimo Tags: ORIGINAL ARTICLE Source Type: research

Bullous dermatosis associated with complex regional pain syndrome
(Source: International Wound Journal)
Source: International Wound Journal - January 31, 2017 Category: Surgery Authors: Bevin Bhoyrul, Mark J Goodfield Tags: LETTER TO THE EDITOR Source Type: research

A new option for definitive burn wound closure  – pair matching type of retrospective case–control study of hand burns in the hospitalised patients group in the Dr Stanislaw Sakiel Centre for Burn Treatment between 2009 and 2015
Abstract Nearly 80% of all burns include the hands of affected individuals. Skin grafting is the gold standard in burns treatment, but in the case of the burn wound bed, it may require the necessity of utilising skin substitutes to facilitate closure. The aim of this study is to assess the impact of a porcine‐derived wound dressing (Oasis™) for application to hand burns compared to a synthetic dressing (Suprathel™). Comparative assessments were made, including the time to heal, quality of healing and pain intensity. A retrospective, unblinded, matching pair case‐control of hand burns was performed. A contro...
Source: International Wound Journal - January 31, 2017 Category: Surgery Authors: Justyna Glik, Marek Kawecki, Diana Kitala, Agnieszka Klama ‐Baryła, Wojciech Łabuś, Marek Grabowski, Agata Durdzińska, Mariusz Nowak, Marcelina Misiuga, Aleksandra Kasperczyk Tags: ORIGINAL ARTICLE Source Type: research

Treatment of standardised wounds with pure epidermal micrografts generated with an automated device
This study shows an effect of epidermal micrografts in a standardised human wound model and supports the positive impact of keratinocytes on early wound healing as described in literature. Long‐term effects of epidermal grafting deserve further studies. (Source: International Wound Journal)
Source: International Wound Journal - January 31, 2017 Category: Surgery Authors: Gregor Buehrer, Andreas Arkudas, Raymund E Horch Tags: ORIGINAL ARTICLE Source Type: research

Dakin's solution: is there a place for it in the 21st century?
We report the case of a 52‐year‐old diabetic woman who was admitted for sepsis because of a severely infected diabetic foot. Urgent surgical drainage and debridement left a 9 × 9‐cm deep, complex, infected wound with both bone and tendon involvement. Treatment with local negative pressure was unsuccessful. DS was regularly instilled through a tube left in the wound dressing. A marked improvement was observed with this strategy as the wound bed was much cleaner and fully granulated after 6 weeks. No adverse effects were noted. This case debunks the myth that topical antiseptics necessarily impair wound healing. ...
Source: International Wound Journal - January 31, 2017 Category: Surgery Authors: Bruno Duarte, Joana Cabete, Ana Formiga, Jos é Neves Tags: ORIGINAL ARTICLE Source Type: research

Is low ‐molecular‐weight heparin beneficial to chronic ulcers? A meta‐analysis of randomised control trials
(Source: International Wound Journal)
Source: International Wound Journal - January 31, 2017 Category: Surgery Authors: Chia ‐Yu Huang, Mun‐Yau Choong Tags: LETTER TO THE EDITOR Source Type: research

Safety and efficacy of intramuscular human placenta ‐derived mesenchymal stromal‐like cells (cenplacel [PDA‐002]) in patients who have a diabetic foot ulcer with peripheral arterial disease
The objective of this study was to examine the safety of cenplacel (PDA‐002) in patients with peripheral arterial disease (PAD) and a diabetic foot ulcer (DFU). Cenplacel is a mesenchymal‐like cell population derived from full‐term human placenta. This phase 1, dose‐escalation study investigated cenplacel in diabetic patients with chronic DFUs (Wagner grade 1 or grade 2) and PAD [ankle‐brachial index (ABI)>0·5 and ≤0·9], enrolled sequentially into each of four dose cohorts (3 × 106, 10 × 106, 30 × 106 and 100 × 106 cells; administered intramuscularly on study days 1 and...
Source: International Wound Journal - January 30, 2017 Category: Surgery Authors: Stephanie C Wu, Richard Pollak, Robert G Frykberg, Wei Zhou, Maha Karnoub, Vladimir Jankovic, Steven A Fischkoff, Denesh Chitkara Tags: ORIGINAL ARTICLE Source Type: research

Primary cutaneous diffuse large B ‐cell lymphoma presenting as chronic non‐healing ulcer
We present the case of a 91‐year‐old female with an unusual manifestation of primary cutaneous diffuse large B‐cell lymphoma, mimicking other more prevalent diseases like chronic non‐healing venous ulceration. Dermatopathologic evaluation rendered the correct diagnosis. A discussion of this rare presentation is important for clinician consideration to prevent misdiagnosis and prolongation of proper management in patients with chronic non‐healing leg ulcers. (Source: International Wound Journal)
Source: International Wound Journal - January 24, 2017 Category: Surgery Authors: Victoria L Billero, Charlotte E LaSenna, Marco Romanelli, Alessio Giubellino, Robert A Brenes, Paolo Romanelli Tags: ORIGINAL ARTICLE Source Type: research

Associated use of silicone –vitamin E gauzes and α‐tocopherol acetate oil in healing of skin graft donor sites
ABSTRACT Split‐thickness skin graft is one of the most used procedures in plastic surgery. This procedure involves numerous painful dressings at the donor site. α‐Tocopherol acetate has anti‐oxidative and anti‐inflammatory properties and it can reduce the local bacterial growth, thereby promoting wound healing. We designed a prospective study to evaluate the effects of two different kinds of dressings at skin graft donor sites. A total of 30 patients were subjected to daily dressings with α‐tocopherol acetate oil and traditional moist gauzes (group 1). Another 30 patients were subjected to dressings e...
Source: International Wound Journal - January 23, 2017 Category: Surgery Authors: Antonio Stanizzi, Manuela Bottoni, Caterina Tartaglione, Elisa Bolletta, Giovanni Di Benedetto Tags: ORIGINAL ARTICLE Source Type: research

Reply: to Chronic venous ulcer treatment with topical sevoflurane by Imbern ón et al.
(Source: International Wound Journal)
Source: International Wound Journal - January 10, 2017 Category: Surgery Authors: F. D ámaso Fernández‐Ginés, Manuel Cortiñas‐Sáenz, Ana Navajas‐Gómez de Aranda, Rodrigo Yoldi Bocanegra, Francisco Sierra‐García Tags: LETTER TO THE EDITOR Source Type: research

Calendar
(Source: International Wound Journal)
Source: International Wound Journal - January 4, 2017 Category: Surgery Tags: CALENDAR OF EVENTS Source Type: research

Society news
(Source: International Wound Journal)
Source: International Wound Journal - January 4, 2017 Category: Surgery Tags: SOCIETY NEWS Source Type: research

News and views
(Source: International Wound Journal)
Source: International Wound Journal - January 4, 2017 Category: Surgery Tags: NEWS AND VIEWS Source Type: research

Innovation in wound healing
(Source: International Wound Journal)
Source: International Wound Journal - January 4, 2017 Category: Surgery Authors: Keith Harding, Douglas Queen Tags: EDITORIAL Source Type: research

Issue Information
(Source: International Wound Journal)
Source: International Wound Journal - January 4, 2017 Category: Surgery Tags: ISSUE INFORMATION Source Type: research

Effectiveness of a multi ‐layer foam dressing in preventing sacral pressure ulcers for the early acute care of patients with a traumatic spinal cord injury: comparison with the use of a gel mattress
Abstract Individuals with spinal cord injury are at risk of sacral pressure ulcers due to, among other reasons, prolonged immobilisation. The effectiveness of a multi‐layer foam dressing installed pre‐operatively in reducing sacral pressure ulcer occurrence in spinal cord injured patients was compared to that of using a gel mattress, and stratified analyses were performed on patients with complete tetraplegia and paraplegia. Socio‐demographic and clinical data were collected from 315 patients admitted in a level‐I trauma centre following a spinal cord injury between April 2010 and March 2016. Upon arrival to the em...
Source: International Wound Journal - January 3, 2017 Category: Surgery Authors: Andr éane Richard‐Denis, Cynthia Thompson, Jean‐Marc Mac‐Thiong Tags: ORIGINAL ARTICLE Source Type: research

Soft silicone foam dressing is more effective than polyurethane film dressing for preventing intraoperatively acquired pressure ulcers in spinal surgery patients: the Border Operating room Spinal Surgery (BOSS) trial in Japan
International Wound Journal, EarlyView. (Source: International Wound Journal)
Source: International Wound Journal - December 7, 2016 Category: Surgery Source Type: research

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International Wound Journal, Ahead of Print. (Source: International Wound Journal)
Source: International Wound Journal - December 7, 2016 Category: Surgery Source Type: research

Impact of Hallux Valgus related of quality of life in Women
Abstract The purpose of this study is to analyse and compare the impact of hallux valgus (HV) in a sample of adult women with varying degrees of HV scores obtained with regard to foot health and health in general. A total 100 female patients of mean age 43·04 ± 16·84 years who attended a podiatric clinic were asked to answer a questionnaire. The degree of deformity, HV, was determined on both feet of the patients using the Manchester Scale tool and the scores from the Foot Health Status Questionnaire were compared. Participants with varying degrees of HV recorded lower scores in Se...
Source: International Wound Journal - December 6, 2016 Category: Surgery Authors: Patricia Palomo ‐López, Ricardo Becerro‐de‐Bengoa‐Vallejo, Marta Elena Losa‐Iglesias, David Rodríguez‐Sanz, César Calvo‐Lobo, Daniel López‐López Tags: ORIGINAL ARTICLE Source Type: research

Successful salvage and reconstruction of a finger threatened by Vibrio vulnificus necrotising fasciitis using fenestrated ‐type artificial dermis and three steps of topical negative pressure wound therapy
We report a case of an elderly patient with end‐stage renal disease undergoing haemodialysis, who developed necrotising fasciitis following infection by V. vulnificus through a puncture injury while cleaning fish. A successful salvage and reconstruction surgery was performed using fenestrated‐type artificial dermis followed by negative pressure wound therapy. This case presents a reasonable treatment option for threatening V. vulnificus necrotising fasciitis with compartment syndrome. (Source: International Wound Journal)
Source: International Wound Journal - November 30, 2016 Category: Surgery Authors: Chi ‐Yu Wang, Hao‐Yu Chiao, Chang‐Yi Chou, Chien‐Ju Wu, Chun‐Kai Chang, Tzi‐Shiang Chu, Niann‐Tzyy Dai Tags: ORIGINAL ARTICLE Source Type: research

Keloid progression: a stiffness gap hypothesis
ABSTRACT Keloids are fibroproliferative skin disorders characterised clinically by continuous horizontal progression and post‐surgical recurrence and histologically by the accumulation of collagen and fibroblast ingredients. Till now, their aetiology remains clear, which may cover genetic, environmental and metabolic factors. Evidence in the involvement of local mechanics (e.g. predilection site and typical shape) and the progress in mechanobiology have incubated our stiffness gap hypotheses in illustrating the chronic but constant development in keloid. We put forward that the enlarged gap between extracellular matrix (...
Source: International Wound Journal - November 30, 2016 Category: Surgery Authors: Chenyu Huang, Longwei Liu, Zhifeng You, Bingjie Wang, Yanan Du, Rei Ogawa Tags: ORIGINAL ARTICLE Source Type: research

Poor methodological quality and reporting standards of systematic reviews in burn care management
ABSTRACT The methodological and reporting quality of burn‐specific systematic reviews has not been established. The aim of this study was to evaluate the methodological quality of systematic reviews in burn care management. Computerised searches were performed in Ovid MEDLINE, Ovid EMBASE and The Cochrane Library through to February 2016 for systematic reviews relevant to burn care using medical subject and free‐text terms such as ‘burn’, ‘systematic review’ or ‘meta‐analysis’. Additional studies were identified by hand‐searching five discipline‐specific journals. Two authors i...
Source: International Wound Journal - November 30, 2016 Category: Surgery Authors: Jason Wasiak, Zephanie Tyack, Robert Ware, Nicholas Goodwin, Clovis M Faggion Tags: ORIGINAL ARTICLE Source Type: research

Independent risk factors for the development of skin erosion due to incontinence (incontinence ‐associated dermatitis category 2) in nursing home residents: results from a multivariate binary regression analysis
Abstract The aim of this study was to identify characteristics independently associated with a higher risk of developing skin damage because of incontinence [incontinence‐associated dermatitis (IAD) category 2] in nursing home residents. As part of a larger randomised controlled trial, IAD incidence was monitored for 1 month in a sample of 381 incontinent residents using a validated IAD Severity Categorisation Tool. Data on demographical, physical, functional and psychological characteristics were collected. The overall IAD incidence (category 1–2) was 30·0%, and 6% of the participants developed skin ...
Source: International Wound Journal - November 30, 2016 Category: Surgery Authors: Nele Van Damme, Karen Bussche, Dorien De Meyer, Ann Van Hecke, Sofie Verhaeghe, Dimitri Beeckman Tags: ORIGINAL ARTICLE Source Type: research

Testing the influence of surfactant ‐based wound dressings on proteinase activity
ABSTRACT Proteinases are enzymes that can digest other proteins. In chronic wounds, a sub‐class of these enzymes with the ability to degrade the extracellular matrix (matrix metalloproteinases, MMPs) have been found to both inhibit healing and to be able to aid in enzymatically debriding a wound. Enzymatic debridement using the enzymes present in a wound is generally called autolytic debridement. Clinicians seeking to employ autolytic debridement typically use occlusive materials such as medical honey, alginate dressings and other occlusive dressings. A relatively new class of gel dressings comprised of surfactants are n...
Source: International Wound Journal - November 30, 2016 Category: Surgery Authors: Sunyoung Jeong, Gregory S Schultz, Daniel J Gibson Tags: ORIGINAL ARTICLE Source Type: research

Soft silicone foam dressing is more effective than polyurethane film dressing for preventing intraoperatively acquired pressure ulcers in spinal surgery patients: the Border Operating room Spinal Surgery (BOSS) trial in Japan
Preventing intraoperatively acquired pressure ulcers (IAPUs) in patients undergoing spinal surgery in the prone position using a Relton‐Hall frame is challenging. We investigated the efficacy of soft silicone foam dressings in preventing IAPUs. A prospective dual‐center sham study was conducted among patients undergoing elective spinal surgery in a general hospital and a university hospital in Japan. The incidence of IAPUs that developed when soft silicone foam dressings and polyurethane film dressings were used was compared on two sides in the same patient. IAPUs developed on the chest in 11 of 100 patients (11%). Pol...
Source: International Wound Journal - November 30, 2016 Category: Surgery Authors: Mine Yoshimura, Norihiko Ohura, Junko Tanaka, Shoichi Ichimura, Yusuke Kasuya, Oruto Hotta, Yu Kagaya, Takuya Sekiyama, Mitsuko Tannba, Nao Suzuki Tags: ORIGINAL ARTICLE Source Type: research

Chronic oedema: a prevalent health care problem for UK health services
Abstract Chronic oedema (CO) is a major clinical problem worldwide, which has many important secondary consequences for health, activity and participation. Effective treatment planning and organisation of services is dependent on an understanding of the condition and its epidemiology. This cross‐sectional study was designed to estimate the point prevalence of CO within the health services of one UK urban population and to determine the proportions that have concurrent leg ulceration. Patients with CO in all anatomic sites were ascertained by health care professionals in one acute and one community hospital, all relevant ...
Source: International Wound Journal - November 30, 2016 Category: Surgery Authors: Christine J Moffatt, Vaughan Keeley, Peter J Franks, Anna Rich, Lorraine L Pinnington Tags: ORIGINAL ARTICLE Source Type: research

An unusual presentation of postaxial polydactyly of the foot
ABSTRACT A 6‐month‐old Caucasian baby is described with a postaxial polydactyly of the letf foot. Radiographic examination revealed the accessory digit was composed of soft tissue, some with a tiny osseous element, originated from around the metatarsophalangeal joint, defined by floating type (FT). The parents had consistent difficulty putting shoes. We encountered an exceedingly rare presentation of FT, to our inspection, had neither been previously related in published studies. To the best of our knowledge, this represents the unusual case of congenital deformity lesion on the left foot to be reported in the medical ...
Source: International Wound Journal - November 30, 2016 Category: Surgery Authors: Daniel L ópez‐López, Ricardo Becerro‐de‐Bengoa‐Vallejo, Marta Elena Losa‐Iglesias, Adolfo Laureano Bautista Casasnovas Tags: ORIGINAL ARTICLE Source Type: research

Effectiveness of collagen/oxidised regenerated cellulose/silver ‐containing composite wound dressing for the treatment of medium‐depth split‐thickness skin graft donor site wounds in multi‐morbid patients: a prospective, non‐comparative, single‐centre study
ABSTRACT Split‐thickness skin grafting (STSG) is a widely used method in reconstructive surgery, but donor site wounds (DSWs) are often slow healing and painful. This prospective study evaluated the performance of a composite wound dressing containing collagen/oxidised regenerated cellulose in the treatment of medium‐depth (0·4 mm) DSWs in 25 multi‐morbid patients with chronic leg ulcers requiring STSG. The range of patients' ages was 44–84 years (mean 71·6 years) with DSW sizes ranging between 12 and 162 cm2 (mean 78 cm2). Comorbidities included anticoagulation therapy...
Source: International Wound Journal - November 30, 2016 Category: Surgery Authors: Alexander Konstantinow, Tatjana V Fischer, Johannes Ring Tags: ORIGINAL ARTICLE Source Type: research

A single ‐arm trial indirect comparison investigation: a proof‐of‐concept method to predict venous leg ulcer healing time for a new acellular synthetic matrix matched to standard care control
Abstract To compare data on time to healing from two separate cohorts: one treated with a new acellular synthetic matrix plus standard care (SC) and one matched from four large UK pragmatic, randomised controlled trials [venous leg ulcer (VLU) evidence network]. We introduce a new proof‐of‐concept strategy to a VLU clinical evidence network, propensity score matching and sensitivity analysis to predict the feasibility of the new acellular synthetic matrix plus SC for success in future randomised, controlled clinical trials. Prospective data on chronic VLUs from a safety and effectiveness study on an acellular synthetic...
Source: International Wound Journal - November 21, 2016 Category: Surgery Authors: Ronald Shannon, Andrea Nelson Tags: ORIGINAL ARTICLE Source Type: research

Skin necrosis after filler ‐associated vascular compromise: successful treatment with topical epidermal growth factor
(Source: International Wound Journal)
Source: International Wound Journal - November 14, 2016 Category: Surgery Authors: Ji Yeon Hong, Sun Young Choi, Kapsok Li, Beom Joon Kim Tags: LETTER TO THE EDITOR Source Type: research

Calendar
(Source: International Wound Journal)
Source: International Wound Journal - November 9, 2016 Category: Surgery Tags: CALENDAR OF EVENTS Source Type: research

Society news
(Source: International Wound Journal)
Source: International Wound Journal - November 9, 2016 Category: Surgery Tags: NEWS Source Type: research

News and views
(Source: International Wound Journal)
Source: International Wound Journal - November 9, 2016 Category: Surgery Tags: NEWS AND VIEWS Source Type: research

International Wound Journal 2016: a year in review
(Source: International Wound Journal)
Source: International Wound Journal - November 9, 2016 Category: Surgery Authors: Keith Harding, Douglas Queen Tags: EDITORIAL Source Type: research

Issue Information – Aims and Scope
(Source: International Wound Journal)
Source: International Wound Journal - November 9, 2016 Category: Surgery Tags: ISSUE INFORMATION Source Type: research

Issue Information – JIP
(Source: International Wound Journal)
Source: International Wound Journal - November 9, 2016 Category: Surgery Tags: ISSUE INFORMATION Source Type: research

Low ‐level stretching accelerates cell migration into a gap
Abstract We observed that radially stretching cell monolayers at a low level (3%) increases the rate at which they migrate to close a gap formed by in vitro injury. Wound healing has been shown to accelerate in vivo when deformations are topically applied, for example, by negative pressure wound therapy. However, the direct effect of deformations on cell migration during gap closure is still unknown. Thus, we have evaluated the effect of radially applied, sustained (static) tensile strain on the kinematics of en mass cell migration. Monolayers of murine fibroblasts were cultured on stretchable, linear‐elastic substrates ...
Source: International Wound Journal - October 16, 2016 Category: Surgery Authors: Samer Toume, Amit Gefen, Daphne Weihs Tags: ORIGINAL ARTICLE Source Type: research

Comparison of five systems of classification of diabetic foot ulcers and predictive factors for amputation
Abstract Diabetes mellitus is a common metabolic disorder. Among various complications, diabetic neuropathy and peripheral vascular disorders are closely associated with diabetic foot ulcers (DFUs). Lower extremity ulcers and amputations are ongoing problems among individuals with diabetes. There are several classification systems for DFUs; however, no prognostic system has to date been accepted as the gold standard or the optimum prediction tool for amputations. A retrospective study was designed. Demographic data and baseline laboratory data were gathered and scored or evaluated using five representative DFU classificati...
Source: International Wound Journal - October 9, 2016 Category: Surgery Authors: Byung ‐Joon Jeon, Hwan Jun Choi, Jin Seok Kang, Min Sung Tak, Eun Soo Park Tags: ORIGINAL ARTICLE Source Type: research

Prescribing antibiotics in diabetic foot infection: what is the role of initial microscopy and culture of tissue samples?*
Abstract The aim of this study was to evaluate the role of microscopy, Gram stain and the culture of tissue samples in the antibiotic treatment of patients with diabetic foot infection. A retrospective review of patients with a diabetic foot infection was undertaken. Data analysed included the severity of infection, antibiotic prescribing patterns, microscopy and culture results. A total of 71 patients were included, from whom 114 tissue samples were collected. Gram stain results were in agreement with final culture results in 45·8% (n = 54) of samples. Overall sensitivity and specificity of the Gram s...
Source: International Wound Journal - October 2, 2016 Category: Surgery Authors: Robin Chisman, Danielle Lowry, Mujahid A Saeed, Alok Tiwari, Miruna D David Tags: ORIGINAL ARTICLE Source Type: research

Pedicled medial sural perforator flap for the reconstruction of knee defects
Abstract Soft tissue defects exposing the patellar tendon or bone are common in patients who have experienced trauma or implant infection. The purpose of this article is to present our experience of six patients who underwent reconstruction of soft tissue defects of the knee using a pedicled medial sural perforator flap. Between November 2013 and November 2015, six patients who presented with a soft tissue defect overlying the knee were admitted to our hospital. After adequate debridement or wide excision of the tumour, these patients underwent pedicled medial sural perforator flap placement to resurface the complex soft t...
Source: International Wound Journal - October 2, 2016 Category: Surgery Authors: I ‐Han Chiang, Chia‐Chun Wu, Shyi‐Gen Chen, Chih‐Hsin Wang Tags: ORIGINAL ARTICLE Source Type: research

The silent overall burden of foot disease in a representative hospitalised population
We examined all participants to clinically diagnose foot disease (ulcers, infections and ischaemia) and amputation procedures. Overall, 72 participants (9·8%) [95% confidence interval (CI):7·2–11·3%] had foot disease. Foot ulcers, in 49 participants (6·7%), were independently associated with peripheral neuropathy, peripheral arterial disease, previous foot ulcers, trauma and past surgeon treatment (P 
Source: International Wound Journal - October 2, 2016 Category: Surgery Authors: Peter A Lazzarini, Sheree E Hurn, Suzanne S Kuys, Maarten C Kamp, Vanessa Ng, Courtney Thomas, Scott Jen, Jude Wills, Ewan M Kinnear, Michael C d'Emden, Lloyd F Reed Tags: ORIGINAL ARTICLE Source Type: research

Use of negative pressure wound therapy on malignant wounds  – a case report and review of literature
We present the case of a patient with treatment‐resistant metastatic colon cancer, who developed a chronic abdominal wound with positive margins. A staged reconstruction using NPWT was performed and wound closure allowed the patient to meet eligibility criteria and enrol in a clinical trial for treatment of his oncological disease. Skin closure remained intact until the patient expired 6 months after the wound closure. This case, as well as others in the literature, demonstrated that the use of NPWT should not be considered an absolute contraindication in malignancy. Individualised approaches taking into account the pati...
Source: International Wound Journal - October 2, 2016 Category: Surgery Authors: Stephen S Cai, Arvind U Gowda, Richard H Alexander, Ronald P Silverman, Nelson H Goldberg, Yvonne M Rasko Tags: ORIGINAL ARTICLE Source Type: research