Dysregulation of Metabolic Flexibility: The Impact of mTOR on Autophagy in Neurodegenerative Disease
Publication date: Available online 11 August 2020Source: International Review of NeurobiologyAuthor(s): Kenneth Maiese (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - August 13, 2020 Category: Neuroscience Source Type: research

Enhancing mitophagy as a therapeutic approach for neurodegenerative diseases
Publication date: Available online 11 August 2020Source: International Review of NeurobiologyAuthor(s): Yahyah Aman, Brent Ryan, Silje Bøen Torsetnes, Anne-Brita Knapskog, Leiv Otto Watne, William A. McEwan, Evandro Fei Fang (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - August 13, 2020 Category: Neuroscience Source Type: research

A role for sodium glucose cotransporter 2 inhibitors (SGLT2i) in the treatment of Alzheimer's disease?
Publication date: Available online 11 August 2020Source: International Review of NeurobiologyAuthor(s): Russell Esterline, Jan Oscarsson, Jeffrey Burns (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - August 13, 2020 Category: Neuroscience Source Type: research

Repurposing GLP1 agonists for neurodegenerative diseases
Publication date: Available online 11 August 2020Source: International Review of NeurobiologyAuthor(s): Ioanna Markaki, Kristian Winther, Sergiu-Bogdan Catrina, Per Svenningsson (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - August 13, 2020 Category: Neuroscience Source Type: research

Evidence for pathophysiological commonalities between metabolic and neurodegenerative diseases
Publication date: Available online 11 August 2020Source: International Review of NeurobiologyAuthor(s): Christian Hölscher (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - August 13, 2020 Category: Neuroscience Source Type: research

Antidiabetic drugs for Alzheimer's and Parkinson's diseases: Repurposing insulin, metformin, and thiazolidinediones
Publication date: Available online 11 August 2020Source: International Review of NeurobiologyAuthor(s): Susana Cardoso, Paula I. Moreira (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - August 13, 2020 Category: Neuroscience Source Type: research

Ketotherapeutics for neurodegenerative diseases
Publication date: Available online 11 August 2020Source: International Review of NeurobiologyAuthor(s): Nicholas G. Norwitz, Javier Gilbert Jaramillo, Kieran Clarke, Adrian Soto (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - August 13, 2020 Category: Neuroscience Source Type: research

Cellular senescence in aging and age-related diseases: Implications for neurodegenerative diseases
Publication date: Available online 11 August 2020Source: International Review of NeurobiologyAuthor(s): Erin O. Wissler Gerdes, Yi Zhu, B. Melanie Weigand, Utkarsh Tripathi, Terence C. Burns, Tamar Tchkonia, James L. Kirkland (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - August 13, 2020 Category: Neuroscience Source Type: research

Hormesis: A potential strategic approach to the treatment of neurodegenerative disease
Publication date: Available online 11 August 2020Source: International Review of NeurobiologyAuthor(s): Edward J. Calabrese, Mark P. Mattson, Gaurav Dhawan, Rachna Kapoor, Vittorio Calabrese, James Giordano (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - August 13, 2020 Category: Neuroscience Source Type: research

Contributors
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Preface
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): Grażyna Söderbom, Russell Esterline, Jan Oscarsson, Mark P. Mattson (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter One - Status and future directions of clinical trials in Alzheimer's disease
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): Germán Plascencia-Villa, George Perry (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter Two - Tracking the potential involvement of metabolic disease in Alzheimer's disease—Biomarkers and beyond
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): José A. Luchsinger, Henrik Zetterberg (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter Three - Brain glucose and ketone utilization in brain aging and neurodegenerative diseases
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): Dimitrios Kapogiannis, Konstantinos I. Avgerinos (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter Four - Disturbances in brain energy metabolism in insulin resistance and diabetes and Alzheimer's disease — Learnings from brain imaging biomarkers
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): Kerstin Heurling, Edvin Johansson, Antoine Leuzy (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter Five - APOE and metabolic dysfunction in Alzheimer's disease
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): Lance A. Johnson (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter Six - Status and future directions of clinical trials in Parkinson's disease
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): Grażyna Söderbom (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter Seven - Involvement of GABAergic interneuron dysfunction and neuronal network hyperexcitability in Alzheimer's disease: Amelioration by metabolic switching
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): Mark P. Mattson (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter Eight - The mitochondrial hypothesis: Dysfunction, bioenergetic defects, and the metabolic link to Alzheimer's disease
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): Russell H. Swerdlow (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter Nine - MAM and C99, key players in the pathogenesis of Alzheimer’s disease
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): Marta Pera, Jorge Montesinos, Delfina Larrea, Rishi R. Agrawal, Kevin R. Velasco, Irina G. Stavrovskaya, Taekyung D. Yun, Estela Area-Gomez (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter Ten - Experimental studies of mitochondrial and lysosomal function in in vitro and in vivo models relevant to Parkinson's disease genetic risk
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): Ria Thomas, Penelope J. Hallett, Ole Isacson (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter Eleven - Endosomal-lysosomal dysfunction in metabolic diseases and Alzheimer's disease
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): Michael F. Almeida, Ben A. Bahr, Stephen T. Kinsey (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter Twelve - Neuroinflammation, microglial activation, and glucose metabolism in neurodegenerative diseases
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): Paul Edison (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter Thirteen - The NLRP3 inflammasome as a bridge between neuro-inflammation in metabolic and neurodegenerative diseases
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): Grażyna Söderbom, Bai-Yun Zeng (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter Fourteen - Impact of circadian and diurnal rhythms on cellular metabolic function and neurodegenerative diseases
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): S. Kendall Smith, Erik S. Musiek (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Chapter Fifteen - The impact of neurovascular, blood-brain barrier, and glymphatic dysfunction in neurodegenerative and metabolic diseases
Publication date: 2020Source: International Review of Neurobiology, Volume 154Author(s): Molly Braun, Jeffrey J. Iliff (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 30, 2020 Category: Neuroscience Source Type: research

Neuroinflammation, microglial activation, and glucose metabolism in neurodegenerative diseases
Publication date: Available online 24 July 2020Source: International Review of NeurobiologyAuthor(s): Paul Edison (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 26, 2020 Category: Neuroscience Source Type: research

MAM and C99, key players in the pathogenesis of Alzheimer’s disease
Publication date: Available online 22 July 2020Source: International Review of NeurobiologyAuthor(s): Marta Pera, Jorge Montesinos, Delfina Larrea, Rishi R. Agrawal, Kevin R. Velasco, Irina G. Stavrovskaya, Taekyung D. Yun, Estela Area-Gomez (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 24, 2020 Category: Neuroscience Source Type: research

Status and future directions of clinical trials in Alzheimer's disease
Publication date: Available online 20 July 2020Source: International Review of NeurobiologyAuthor(s): Germán Plascencia-Villa, George Perry (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 21, 2020 Category: Neuroscience Source Type: research

The NLRP3 inflammasome as a bridge between neuro-inflammation in metabolic and neurodegenerative diseases
Publication date: Available online 17 July 2020Source: International Review of NeurobiologyAuthor(s): Grażyna Söderbom, Bai-Yun Zeng (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 17, 2020 Category: Neuroscience Source Type: research

The impact of neurovascular, blood-brain barrier, and glymphatic dysfunction in neurodegenerative and metabolic diseases
Publication date: Available online 14 July 2020Source: International Review of NeurobiologyAuthor(s): Molly Braun, Jeffrey J. Iliff (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 14, 2020 Category: Neuroscience Source Type: research

Brain glucose and ketone utilization in brain aging and neurodegenerative diseases
Publication date: Available online 10 July 2020Source: International Review of NeurobiologyAuthor(s): Dimitrios Kapogiannis, Konstantinos I. Avgerinos (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 11, 2020 Category: Neuroscience Source Type: research

Endosomal-lysosomal dysfunction in metabolic diseases and Alzheimer's disease
Publication date: Available online 10 July 2020Source: International Review of NeurobiologyAuthor(s): Michael F. Almeida, Ben A. Bahr, Stephen T. Kinsey (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 11, 2020 Category: Neuroscience Source Type: research

Tracking the potential involvement of metabolic disease in Alzheimer's disease—Biomarkers and beyond
Publication date: Available online 10 July 2020Source: International Review of NeurobiologyAuthor(s): José A. Luchsinger, Henrik Zetterberg (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 11, 2020 Category: Neuroscience Source Type: research

Experimental studies of mitochondrial and lysosomal function in in vitro and in vivo models relevant to Parkinson's disease genetic risk
Publication date: Available online 10 July 2020Source: International Review of NeurobiologyAuthor(s): Ria Thomas, Penelope J. Hallett, Ole Isacson (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 11, 2020 Category: Neuroscience Source Type: research

Disturbances in brain energy metabolism in insulin resistance and diabetes and Alzheimer's disease — Learnings from brain imaging biomarkers
Publication date: Available online 11 July 2020Source: International Review of NeurobiologyAuthor(s): Kerstin Heurling, Edvin Johansson, Antoine Leuzy (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 11, 2020 Category: Neuroscience Source Type: research

APOE and metabolic dysfunction in Alzheimer's disease
Publication date: Available online 11 July 2020Source: International Review of NeurobiologyAuthor(s): Lance A. Johnson (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 11, 2020 Category: Neuroscience Source Type: research

Status and future directions of clinical trials in Parkinson's disease
Publication date: Available online 11 July 2020Source: International Review of NeurobiologyAuthor(s): Grażyna Söderbom (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 11, 2020 Category: Neuroscience Source Type: research

Impact of circadian and diurnal rhythms on cellular metabolic function and neurodegenerative diseases
Publication date: Available online 10 July 2020Source: International Review of NeurobiologyAuthor(s): S. Kendall Smith, Erik S. Musiek (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 10, 2020 Category: Neuroscience Source Type: research

Involvement of GABAergic interneuron dysfunction and neuronal network hyperexcitability in Alzheimer's disease: Amelioration by metabolic switching
Publication date: Available online 10 July 2020Source: International Review of NeurobiologyAuthor(s): Mark P. Mattson (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 10, 2020 Category: Neuroscience Source Type: research

The mitochondrial hypothesis: Dysfunction, bioenergetic defects, and the metabolic link to Alzheimer's disease
Publication date: Available online 10 July 2020Source: International Review of NeurobiologyAuthor(s): Russell H. Swerdlow (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - July 10, 2020 Category: Neuroscience Source Type: research

Contributors
Publication date: 2020Source: International Review of Neurobiology, Volume 153Author(s): (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - June 18, 2020 Category: Neuroscience Source Type: research

Preface
Publication date: 2020Source: International Review of Neurobiology, Volume 153Author(s): Natalie P. Witek, Christopher G. Goetz, Glenn T. Stebbins (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - June 18, 2020 Category: Neuroscience Source Type: research

Chapter One - Better than nothing: A historical account of placebos and placebo effects from modern to contemporary medicine
Publication date: 2020Source: International Review of Neurobiology, Volume 153Author(s): Marco Annoni (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - June 18, 2020 Category: Neuroscience Source Type: research

Chapter Two - Determinants of placebo effects
Publication date: 2020Source: International Review of Neurobiology, Volume 153Author(s): Sharlet Anderson, Glenn T. Stebbins (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - June 18, 2020 Category: Neuroscience Source Type: research

Chapter Three - Strategies to minimize placebo effects in research investigations
Publication date: 2020Source: International Review of Neurobiology, Volume 153Author(s): Filipe B. Rodrigues, Joaquim J. Ferreira (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - June 18, 2020 Category: Neuroscience Source Type: research

Chapter Four - Maximizing placebo response in neurological clinical practice
Publication date: 2020Source: International Review of Neurobiology, Volume 153Author(s): Louise-Laure Mariani, Jean-Christophe Corvol (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - June 18, 2020 Category: Neuroscience Source Type: research

Chapter Five - Statistical methods in handling placebo effect
Publication date: 2020Source: International Review of Neurobiology, Volume 153Author(s): Rema Raman (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - June 18, 2020 Category: Neuroscience Source Type: research

Chapter Six - Nocebo and lessebo effects
Publication date: 2020Source: International Review of Neurobiology, Volume 153Author(s): Tiago A. Mestre (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - June 18, 2020 Category: Neuroscience Source Type: research

Chapter Seven - Deception and the ethics of placebo
Publication date: 2020Source: International Review of Neurobiology, Volume 153Author(s): A. Jon Stoessl (Source: International Review of Neurobiology)
Source: International Review of Neurobiology - June 18, 2020 Category: Neuroscience Source Type: research