International Journal of Surgical Pathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Renal Oncocytoma With Perinephric Fat Invasion
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - September 6, 2016 Category: Pathology Authors: Williamson, S. R. Tags: Images in Pathology Source Type: research

Annulate Lamellae in a Desmoplastic Small Round Cell Tumor
(Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - September 6, 2016 Category: Pathology Authors: Alfaro-Cervello, C., Soriano-Navarro, M., Cebrian-Silla, A., Forteza-Vila, J. Tags: Images in Pathology Source Type: research

Well-Differentiated Liposarcoma With Hibernoma-Like Morphology
Well-differentiated liposarcoma (WDL) can show a morphologic spectrum, including lipoma-like, sclerosing and inflammatory subtypes. It does not metastasize but can dedifferentiate, acquiring metastatic potential. Hibernomas are benign neoplasms that show variable differentiation toward brown fat, and can sometimes occur in the abdomen or retroperitoneum. We illustrate a case of retroperitoneal WDL that showed extensive hibernoma-like morphology, with sheets of multivacuolated adipocytes of varying sizes, with abundant cytoplasm and numerous lipid vacuoles or granular eosinophilic cytoplasm. However, very focally there were...
Source: International Journal of Surgical Pathology - September 6, 2016 Category: Pathology Authors: Hallin, M., Schneider, N., Thway, K. Tags: Pitfalls in Pathology Source Type: research

CD138 Expression Is Observed in the Urothelial Epithelium and in Various Urothelial Carcinomas, and Cannot Be Evidence for Plasmacytoid Urothelial Carcinoma
CD138 (syndecan-1) immunoexpression has been reported to be specific for the plasmacytoid variant of urothelial carcinomas (UCs). The aim of this study was to examine the utility of CD138 immunohistochemistry for diagnosing the plasmacytoid variant of UCs. The extent and intensity of CD138 immunostaining were evaluated in 22 infiltrating UCs, 2 other infiltrating carcinomas, 15 noninvasive urothelial lesions, 3 other benign lesions, and perilesional normal tissues. CD138 immunostaining of the normal urothelial epithelium was universally diffuse and strong. In addition, all 42 cases of urinary tract lesions exhibited positi...
Source: International Journal of Surgical Pathology - September 6, 2016 Category: Pathology Authors: Goto, K. Tags: Original Articles Source Type: research

Clinicopathological Significance of the Proliferation Markers Ki67, RacGAP1, and Topoisomerase 2 Alpha in Breast Cancer
Conclusion. This study showed that the overexpressions of Ki67, RacGAP1, and TOP2a affect the prognosis adversely, thus to develop target therapies against RacGAP1 and TOP2a as well as using Ki67 as a part of routine pathology practice might be beneficial in breast cancer therapy and prediction of prognosis. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - September 6, 2016 Category: Pathology Authors: Sahin, S., Isık Gönül, I., Cakır, A., Seckin, S., Uluoglu, O. Tags: Original Articles Source Type: research

A Comparative Study of Intraoperative Cytology and Frozen Sections of Sclerosing Pneumocytoma
In this study, we review and compare the intraoperative cytology and frozen section of 14 cases of SP. SP is characterized by containing 2 cell types: round stromal cells and cuboidal surface cells. The round stromal cells were small with uniform nuclei and inconspicuous nucleoli. The cuboidal surface cells were more differentiated into type II pneumocytes and showed slightly larger in size with intranuclear inclusions. The immunocytochemical double-labeling staining could display 2 distinct population of vimentin-positive round stromal cells and cytokeratin 7–positive cuboidal surface cells. Recognition of the cytol...
Source: International Journal of Surgical Pathology - September 6, 2016 Category: Pathology Authors: Wu, C.-Y., Wang, J., Chang, N.-Y. Tags: Original Articles Source Type: research

Podoplanin Expression Is Correlated With the Progression of Chronic Discoid Lupus Erythematosus to Lip Squamous Cell Carcinoma
The objective of this study was to determine the immunoexpression of podoplanin in samples of patients with DLE and its correlation with the risk of progression to LSCC. In a retrospective study, podoplanin expression was determined using immunohistochemistry in samples from 52 patients with DLE, including 44 patients with untransformed DLE and 8 patients with malignant transformed DLE. Ten samples of normal oral mucosa and 10 samples of LSCC were used as normal and cancer controls, respectively. The results showed that podoplanin expression was observed in 12 of 44 (27.3%) patients with untransformed DLE and in 7 of 8 (87...
Source: International Journal of Surgical Pathology - September 6, 2016 Category: Pathology Authors: Gao, X., Ma, L., Zhou, Z., Jian, X., Liu, W. Tags: Original Articles Source Type: research

Cyclin D1 Expression in Ectomesenchymal Chondromyxoid Tumor of the Anterior Tongue
Ectomesenchymal chondromyxoid tumor (ECT) is a rare benign tumor of uncertain lineage, which almost exclusively affects the anterior tongue. Herein, we report 2 cases of ECT occurring in 58- and 56-year-old males on the right and on the left side of the dorsum of the anterior tongue, measuring 18 mm and 10 mm, respectively. Despite positive resection margin in one case, none of the tumors recurred during follow-up of 6 and 5 years. Microscopically, both tumors had lobular architecture with a mixture of solid, microcystic, and chondromyxoid areas. The tumor cells were polygonal or elongated and showed mild atypia in one cas...
Source: International Journal of Surgical Pathology - September 6, 2016 Category: Pathology Authors: Laco, J., Mottl, R., Höbling, W., Ihrler, S., Grossmann, P., Skalova, A., Ryska, A. Tags: Original Articles Source Type: research

Autoantibodies in Autoimmune Liver Diseases--Methods of Detection and Interpretation: An Update for the Reporting Pathologist
Autoimmune liver disease (AILD) is a type of chronic liver disease with autoimmune etiology. The diagnosis of the disease is multipronged and detection of autoantibodies in AILDs is an important diagnostic tool and it also helps in the classification of the disease. There are multiple autoantibodies that are detected in AILDs but none is diagnostic. Moreover, these autoantibodies are detected in many other pathological and nonpathological conditions. So the significance of seropositivity for these autoantibodies should be known by both the pathologists as well as the clinicians. In addition, there is prognostic significanc...
Source: International Journal of Surgical Pathology - September 6, 2016 Category: Pathology Authors: Mitra, S., Minz, R. W. Tags: Review Source Type: research

Pindborg Tumor Presenting as a Nasal Polyp: Immunohistology and Ultrastructural Features of a Rare Case, With Review of the Literature
We present a rare case of calcifying epithelial odontogenic tumor presenting as a nasal polyp, posing a diagnostic difficulty. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Mitra, S., Kaur, G., Nada, R., Mohindra, S. Tags: Case Reports Source Type: research

Epithelial Inclusion Cyst in Conjunctival Melanoma
Conjunctival melanoma is the second most common conjunctival malignancy. Its differential diagnosis with other conjunctival melanocytic neoplasms is inherently difficult. The presence of epithelial cysts is a useful feature in conjunctival tumors and favors a benign lesion. Herein 2 cases of conjunctival melanoma with cysts are presented. To the best of our knowledge, this is the first series of conjunctival melanoma with epithelial inclusion cysts. This series emphasizes the importance of considering several malignant features when reviewing conjunctival melanocytic lesions, as malignancy can exist even in the presence of...
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Esposito, E., Zoroquiain, P., Mastromonaco, C., Morales, M. C., Belfort Neto, R., Burnier, M. Tags: Case Reports Source Type: research

Anaplastic Sarcoma of the Kidney: A Rare Unique Renal Neoplasm
Anaplastic sarcoma of the kidney (ASK) is an extremely rare tumor, which usually presents as a large renal mass. Microscopically, the tumor is composed of pleomorphic mesenchymal spindle cells with marked atypia, associated with chondroid differentiation and focal round primitive mesenchymal cells. Herein, we present a case of anaplastic sarcoma of the kidney in a 3-year-old female, who presented with a large abdominal mass. To the best of our knowledge, less than 25 cases are reported in the literature. In addition, this is the first case reported from the Middle East. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Arabi, H., Al-Maghraby, H., Yamani, A., Yousef, Y., Huwait, H. Tags: Case Reports Source Type: research

Metastatic Renal Cell Carcinoma in a Hepatic Hemangioma: A Case Report and Review of the Literature
We report the case of 55-year-old female with biopsy-proven clear cell renal cell carcinoma with a suspicious lesion found in the liver who presented for right radical nephrectomy and partial hepatectomy. Histologic evaluation of the hepatic specimen demonstrated metastatic renal cell carcinoma within a hepatic hemangioma. Herein we provide a review of the literature for this uncommon scenario. (Source: International Journal of Surgical Pathology)
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Cohen, J., Meunier, R., Jamshed, S., Karam, A. R., Yates, J., Wang, X., LaFemina, J. Tags: Case Reports Source Type: research

Malakoplakia Associated With Multiple Adenomas of the Colon: An Extremely Rare Incidental Finding
Malakoplakia in the colon has been described either as part of a systemic disease with a diffuse presentation or as a rare incidental finding associated usually with an adenocarcinoma. To our knowledge, the association of malakoplakia with colonic adenoma is very rare and only 5 cases, including the present case, have been reported so far. Here, we describe a case of malakoplakia coexisting with multiple sigmoid colonic adenomas in a 67-year-old patient without any underlying inflammatory or infectious disease and with no history of immunosuppressive treatment. As far as we are concerned, this is the first description of m...
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Zanelli, M., Ragazzi, M., Serra, S., Bellafiore, S., Ascani, S., De Marco, L. Tags: Case Reports Source Type: research

Primitive Neuroectodermal Tumor of the Stomach: A Case Report
Ewing sarcoma/primitive neuroectodermal tumor (ES/PNET) is a highly aggressive small round cell tumor that mainly occurs in the bone or soft tissue of children or young adults but is extremely rare in the stomach. A 55-year-old man presented with melena and anemia. On endoscopy, an ulcerofungating mass was observed in the high body and total gastrectomy was performed. Histologically, the mass consisted of small round cells with scanty cytoplasm and inconspicuous nucleoli. They often formed perivascular pseudorosettes and multinucleated giant cells were frequently observed. The tumor cells strongly expressed CD99, FLI1, and...
Source: International Journal of Surgical Pathology - August 4, 2016 Category: Pathology Authors: Song, M. J., An, S., Lee, S. S., Kim, B. S., Kim, J. Tags: Case Reports Source Type: research