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Emerging atypical non-lactose-fermenting phenotypic variants of klebsiella pneumoniae and escherichia coli in admitted patients of a trauma centre
Vijeta Bajpai, Purva MathurIndian Journal of Medical Microbiology 2019 37(4):593-594 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Vijeta Bajpai Purva Mathur Source Type: research

A rare aetiology of spinal epidural abscess
Lata Sheoran, Neeraj Goel, Shankar Acharya, Nitin Adsul, Chand WattalIndian Journal of Medical Microbiology 2019 37(4):590-592 Spinal epidural abscess (SEA) due to Streptococcus pneumoniae is a rare entity, but it is associated with high mortality. Here, we describe a rare case of pneumococcal SEA in an immunocompetent adult who presented with fever, lower back pain and paresis. Central nervous system examination revealed a decreased power in bilateral lower limbs. Magnetic resonance imaging of the lumbosacral spine showed loculated pus collection in the epidural space at the level of L4–L5 vertebrae. Pus obt...
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Lata Sheoran Neeraj Goel Shankar Acharya Nitin Adsul Chand Wattal Source Type: research

A rare association of Mycobacterium tuberculosis infection of kidney and urinary tract with immunoglobulin A nephropathy
Immanuel Pradeep, Sneha Haridas Anupama, Priyanka Koshy, Abraham Kurien, Anusha Rohit, Milly Mathew, Rajeevalochana Parthasarathy, Georgi AbrahamIndian Journal of Medical Microbiology 2019 37(4):587-589 Mycobacterium tuberculosis(MTB)-related secondary immunoglobulin A (IgA) nephropathy is reported in a 72-year-old male patient. The patient was diagnosed to have MTB infection of the kidney and genitourinary tract which was diagnosed by the demonstration of the organism by GeneXpert Ultra and culture. Concurrent kidney biopsy showed IgA nephropathy. The patient responded to urethral double-J stenting and four-drug antitube...
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Immanuel Pradeep Sneha Haridas Anupama Priyanka Koshy Abraham Kurien Anusha Rohit Milly Mathew Rajeevalochana Parthasarathy Georgi Abraham Source Type: research

Assessment of two immunoassays for detection of IgM antibodies to scrub typhus using a serum panel
Divyaa Elangovan, Susmitha Perumalla, Winsley Rose, Valsan Philip Verghese, Joy Mammen, MS Gowri, John Antony Jude PrakashIndian Journal of Medical Microbiology 2019 37(4):584-586Laboratory tests are necessary for diagnosis of scrub typhus (ST) especially in the absence of the distinctive eschar. Performance of an ELISA and ICT (immunochromatography) to detect IgM antibodies to scrub typhus was assessed using a panel of 346 sera chosen from healthy individuals, those with scrub typhus and scrub-typhus like illness. A sensitivity of 98.7% for ST IgM ICT and 97.4% for ST IgM ELISA was observed while spe...
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Divyaa Elangovan Susmitha Perumalla Winsley Rose Valsan Philip Verghese Joy Mammen MS Gowri John Antony Jude Prakash Source Type: research

Interaction of human immunodeficiency virus-1 and human immunodeficiency virus-2 capsid amino acid variants with human tripartite motif 5 & #945; protein SPRY domain and its association with pathogenesis
Conclusion: Polymorphisms in the capsid protein with both HIV-1- and HIV-2-monoinfected individuals showed the difference in the docking energy from the wild type. This is the first study which documents the difference in the usage of loop between the two HIV types for interaction with huTRIM5α. Variations in the capsid protein result in alteration in the binding to the restriction factor huTRIM5α. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Veena Vadhini Ramalingam Suganya Subramanian G John Fletcher Priscilla Rupali George Varghese Susanne Pulimood Lakshmanan Jeyaseelan Balaji Nandagopal Gopalan Sridharan Rajesh Kannangai Source Type: research

Epidemiology and phylogenetic analysis of human rhinovirus/Enterovirus in Odisha, Eastern India
Conclusion: The genotyping and phylogenetic analysis of the HRVs in the current study shows its circulatory pattern, association with risk factors and evolutionary dynamics. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Swagatika Panda Nirmal Kumar Mohakud Soumya Panda Subrat Kumar Source Type: research

Currently circulating genotypes of hepatitis E virus in India, 2014 & #8211;2018
Conclusion: The HEV genotypes 1a was observed to be the currently circulating strain in the regions studied. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Fernandes M Mevis Sasidharanpillai Sabeena Ramachandran Sanjay Sudandiradas Robin Santhosha Devadiga Varamballi Prasad Dsa Oliver Alyusif Ameen Govindakarnavar Arunkumar Source Type: research

Types of human papillomavirus observed in hospital-based population
Conclusions: The study highlighted the type of HPV infection seen among the hospital-based population. For better screening, HPV tests available in the market should include all the types seen in the population. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Priyanka Wagh Priyanka Kulkarni Shilpa Kerkar Hemant Tongaonkar Kedar Deodhar Bharat Rekhi Vinita Salvi Hemangi Chaudhari Himangi Warke Jayanti Mania-Pramanik Source Type: research

Immune response during influenza virus infection among the population of Assam, Northeast India
Conclusions: The study revealed a differential cytokine profile during influenza virus infection in the population, which may influence disease severity. An extended study on host immune response may provide better insights for the use of cytokine antagonists in therapeutic treatments among severe cases of influenza virus infection. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Mousumi Dutta Prafulla Dutta Subhash Medhi Biswajyoti Borkakoty Dipankar Biswas Source Type: research

Evaluating the PGMY-centre hospitalier universitaire vaudois assay as a cost-effective tool for human papillomavirus genotyping in HIV-infected women
Conclusion: The CHUV assay had an acceptable sensitivity, but it lacked specificity for HPV detection. Despite the lower rates of detection of multiple infections from clinical samples, better results were obtained with the WHO reference samples and the ability of the assay to identify the entire range of genotypes suggests that it can be an efficient tool for genotyping. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Pallavi Ravindra Baliga Raghavendran Anantharam Vinotha Thomas Priscilla Rupali Manu Chopra Susanne Pulimood Jessie Lionel Abraham Peedicayil Rajesh Kannangai Manu Gnanamony Priya Abraham Source Type: research

Epidemiology and Antifungal Susceptibility of Infections Caused by Trichosporon Species: An Emerging Non-Candida and Non-Cryptococcus Yeast Worldwide
Conclusion: T. asahii was the most common isolate. Disseminated trichosporonosis is being increasingly reported worldwide including India and represents a challenge for both diagnosis and species identification. Prognosis is limited, and antifungal regimens containing triazoles appear to be the best therapeutic approach. In addition, accurate identification, removal of central venous lines and voriconazole-based treatment along with control of underlying conditions were associated with favourable outcomes. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Sukhwinder Singh Malini Rajinder Capoor Swati Varshney Dipendra Kumar Gupta Pradeep Kumar Verma V Ramesh Source Type: research

Is it safe to do a single-stage implant exit and primary hip replacement ? clinical and microbiological profiling
Conclusion: This study suggests that implant exit and simultaneous arthroplasty for failed fracture fixation should be done with caution due to the high possibility of infection. It may be prudent to opt for a 2 stage revision. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Rahul George TD Hariharan A Arunshankar Divyaa Elangovan Binesh Lal VJ Chandy AT Oommen Pradeep Mathew Poonnoose Source Type: research

Adaptation of blaNDMthrough IncP plasmid within broad host range
Conclusion: This study was able to underscore the presence of IncP plasmid that was harbouring blaNDMand was maintained within diverse host. The finding also highlights the adaptation of the broad-host-range plasmid that responds in terms of transcriptional expression under antibiotic exposure. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Nargis Alom Choudhury Deepjyoti Paul Bhaskar Jyoti Das Debadatta Dhar(Chanda) Amitabha Bhattacharjee Source Type: research

The incidence, aetiology and antimicrobial susceptibility of central line-associated bloodstream infections in intensive care unit patients at a private tertiary care hospital in Mumbai, India
Conclusions: The CLABSI rates at a well-equipped tertiary care hospital are still significantly higher than the USA benchmarks. Alarming rates of drug resistance in Gram-negative pathogens were seen. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Tanu Singhal Sweta Shah Pooja Thakkar Reshma Naik Source Type: research

Utility of dried blood spots in detecting helicobacter pylori infection
Conclusion: No significant difference was observed in detecting H. pylori when ELISA was conducted using IVB or DBS stored at 4°C and transported even after 48 h. This confirms that DBS collected even in compromised conditions in the field can be used for detecting infection. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - May 17, 2020 Category: Microbiology Authors: Abhinendra Kumar Sharayu Mhatre Rajesh Dikshit Source Type: research