Genotypic characterisation of Mycobacterium tuberculosis isolates from tuberculous meningitis patients at a tertiary neurocare centre in Southern India
Conclusions: We conclude that there is no apparent association between genotypes of MTB and propensity to infect CNS tissue. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 5, 2017 Category: Microbiology Authors: Akepati Chandramuki Neelam Khanna Elena Shashkina Natalia Kurepina Barun Mathema Barry N Kreiswirth Manjunatha M Venkataswamy Source Type: research

Spectrum of diarrhoeagenic Escherichia coli in paediatric population suffering from diarrhoea and as commensals in healthy children
Conclusion: Multiplex PCR is a rapid method for the simultaneous detection of 11 virulent genes of DEC at a time and it will provide a platform in understanding the diarrheal diseases in a more improved manner. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 5, 2017 Category: Microbiology Authors: Taru Singh Shukla Das VG Ramachandran Sajad Ahmad Dar K Snehaa Rumpa Saha Dheeraj Shah Source Type: research

Departing from PowerPoint default mode: Applying Mayer & #39;s multimedia principles for enhanced learning of parasitology
Conclusions: It is time to depart from default PPT™ and adopt multimedia principles to enhance comprehension and improve short and long term knowledge retention. Further, medical educators may be trained and encouraged to apply multimedia principles for designing and delivering effective lectures. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 5, 2017 Category: Microbiology Authors: Jyoti Mahantesh Nagmoti Source Type: research

Biomedical waste management guidelines 2016: What & #39;s done and what needs to be done
Lipika Singhal, Arpandeep Kaur Tuli, Vikas GautamIndian Journal of Medical Microbiology 2017 35(2):194-198The latest biomedical waste (BMW) management guidelines which have been introduced in 2016 are simplified and made easier so that they can be easily followed by various health agencies. The categories of BMW have been reduced from ten (in 1998) to four in the latest (2016) guidelines. Many changes have been made in these latest guidelines, which have been summarised in the article below. The segregation of hospital waste plays a very important role, so the waste has to be sorted out at the source of generation accordin...
Source: Indian Journal of Medical Microbiology - July 5, 2017 Category: Microbiology Authors: Lipika Singhal Arpandeep Kaur Tuli Vikas Gautam Source Type: research

Statistical analysis of microbiological diagnostic tests
CP Baveja, Prabhav AggarwalIndian Journal of Medical Microbiology 2017 35(2):184-193No study in medical science is complete without application of the statistical principles. Incorrect application of statistical tests causes incorrect interpretation of the study results obtained through hard work. Yet statistics remains one of the most neglected and loathed areas, probably due to the lack of understanding of the basic principles. In microbiology, rapid progress is being made in the field of diagnostic test, and a huge number of studies being conducted are related to the evaluation of these tests. Therefore, a good knowledg...
Source: Indian Journal of Medical Microbiology - July 5, 2017 Category: Microbiology Authors: CP Baveja Prabhav Aggarwal Source Type: research

Molecular biology of Group A Streptococcus and its implications in vaccine strategies
NK BrahmadathanIndian Journal of Medical Microbiology 2017 35(2):176-183Infections due to Streptococcus pyogenes and their complications are a problem of major concern in many countries, including India. Primary prophylaxis with benzathine penicillin is the key to control and prevent sequelae such as acute rheumatic fever and rheumatic heart disease (RF/RHD) or post-streptococcal glomerulonephritis (PSGN). Non-compliance to prophylaxis due to fear of injection and anaphylaxis is major issues in RF/RHD control in India and leads to continued high prevalence of infection and post-streptococcal sequelae. Differing reports on ...
Source: Indian Journal of Medical Microbiology - July 5, 2017 Category: Microbiology Authors: NK Brahmadathan Source Type: research

Globally emerging hantaviruses: An overview
Sara Chandy, Dilip MathaiIndian Journal of Medical Microbiology 2017 35(2):165-175Hantaviruses are known to cause haemorrhagic fever with renal syndrome in Eurasia and hantavirus cardiopulmonary syndrome in the Americas. They are globally emerging pathogens as newer serotypes are routinely being reported. This review discusses hantavirus biology, clinical features and pathogenesis of hantavirus disease, its diagnostics, distribution and mammalian hosts. Hantavirus research in India is also summarised. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 5, 2017 Category: Microbiology Authors: Sara Chandy Dilip Mathai Source Type: research

Current perspectives on biomedical waste management: Rules, conventions and treatment technologies
This article reviews the current perspectives on BMWM and rules, conventions and the treatment technologies used worldwide. BMWM should ideally be the subject of a national strategy with dedicated infrastructure, cradle-to-grave legislation, competent regulatory authority and trained personnel. Improving the management of biomedical waste begins with waste minimisation. These standards, norms and rules on BMWM in a country regulate the disposal of various categories of BMW to ensure the safety of the health-care workers, patients, public and environment. Furthermore, developing models for the monitoring of hospital health-...
Source: Indian Journal of Medical Microbiology - July 5, 2017 Category: Microbiology Authors: Malini R Capoor Kumar Tapas Bhowmik Source Type: research

Molecular monitoring of antimalarial drug resistance in India
Susanta Kumar GhoshIndian Journal of Medical Microbiology 2017 35(2):155-156 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - July 5, 2017 Category: Microbiology Authors: Susanta Kumar Ghosh Source Type: research

Reviewers,2016
Indian Journal of Medical Microbiology 2017 35(1):150-151 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Source Type: research

Clinico-epidemiological profile of dengue cases prevalent in lakhimpur district of Assam
Jitendra SharmaIndian Journal of Medical Microbiology 2017 35(1):148-149 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Jitendra Sharma Source Type: research

Prevalence of bi-component pore-forming toxin genotypes of Staphylococcus aureus causing skin and soft tissue infections
Nagaraj Perumal, Betsy Sowndarya Dass, Stalin Mani, Padma KrishnanIndian Journal of Medical Microbiology 2017 35(1):146-147 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Nagaraj Perumal Betsy Sowndarya Dass Stalin Mani Padma Krishnan Source Type: research

Emergence of ST39 and ST656 extensively drug-resistant Klebsiella pneumoniae isolates in Wenzhou, China
Haiyang Liu, Jonathan Wilksch, Bin Li, Jia Du, Jianming Cao, Xiaoxiao Zhang, Tieli ZhouIndian Journal of Medical Microbiology 2017 35(1):145-146 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Haiyang Liu Jonathan Wilksch Bin Li Jia Du Jianming Cao Xiaoxiao Zhang Tieli Zhou Source Type: research

Introducing rubella vaccine into the national immunisation schedule
Valsan Philip VergheseIndian Journal of Medical Microbiology 2017 35(1):143-145 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Valsan Philip Verghese Source Type: research

Prevalence of multiple drug-resistant Plasmodium falciparum malaria cases in Northeast India
Jitendra Sharma, Siraj Ahmed Khan, Monika Soni, Prafulla DuttaIndian Journal of Medical Microbiology 2017 35(1):140-142 Two numbers of Plasmodium falciparum field isolates from Gossingpara, Runikhata area in Chirang district of Assam had shown multiple mutations in Pfcrt-dhfr-dhps gene (up to seven mutations: One mutation in Pfcrt gene, three mutations in Pfdhfr gene and three mutations in Pfdhps gene). Similarly, two cases in Bat camp, Miao area under Changlang district of Arunachal Pradesh had shown a total of eight mutations, of which one mutation in Pfcrt gene, three mutations in Pfdhfr gene, three mutations in Pfdhps...
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Jitendra Sharma Siraj Ahmed Khan Monika Soni Prafulla Dutta Source Type: research

Carbapenem nonsusceptibility with modified OprD in clinical isolates of Pseudomonas aeruginosa from India
This study was undertaken to investigate OprD porin-mediated carbapenem nonsusceptibility in clinical isolates of Pseudomonas aeruginosa from a tertiary referral hospital of Northeast India. A total of 267 nonduplicate, consecutive clinical isolates of P. aeruginosa were obtained. Mutation and expression levels of OprD gene were determined in carbapenem-nonsusceptible carbapenemase-nonproducing isolates. Among 19 carbapenem-nonsusceptible carbapenemase-nonproducing isolates, 11 of them demonstrated variable band pattern while performing denaturing gradient gel electrophoresis with amplified products of OprD gene. Sequencin...
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Debarati Choudhury Anupam Das Talukdar Manabendra Dutta Choudhury Anand Prakash Maurya Debadatta Dhar Chanda Atanu Chakravorty Amitabha Bhattacharjee Source Type: research

Trends of respiratory syncytial virus sub-types in children hospitalised at a tertiary care centre in Jaipur during 2012 & #8211;2014
M Anjaneya Swamy, Bharti Malhotra, P V. Janardhan Reddy, Jitendra Kumar Tiwari, Neeraj Kumar, Manohar Lal GuptaIndian Journal of Medical Microbiology 2017 35(1):134-136 Respiratory syncytial virus (RSV) causes high mortality and morbidity in infants. The study was planned to determine the trends of RSV sub-types in hospitalised children. Nasopharyngeal aspirate and throat swabs were collected from the hospitalised children up to 5 years of age. Viral nucleic acid was extracted using easyMAG automated extraction system, and real-time reverse transcription polymerase chain reaction was performed. Total positivity for RSV wa...
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: M Anjaneya Swamy Bharti Malhotra P V. Janardhan Reddy Jitendra Kumar Tiwari Neeraj Kumar Manohar Lal Gupta Source Type: research

Trends in spoligotype patterns of Mycobacterium tuberculosis strains in central India
This study aims to understand trends in spoligotype patterns of Mycobacterium tuberculosis (MTB) in Central India. Elucidation of these trends may provide baseline information to understand the transmission dynamics of strains of MTB in the region. Spoligotyping was carried out on 340 MTB strains isolated from clinical samples received from 2007 to 2011. The prevalence of ST26/CAS1_Del, ST11/EAI3_IND, ST288/CAS2, ST25/CAS1_Del and Beijing lineages showed waxing and waning trends. ST26/CAS1_Del and ST11/EAI3_IND lineages were consistently present and were predominant. Well-established lineages showed a consistent presence i...
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Prabha Desikan Devendra S Chauhan Nikita Panwalkar Pragya Sharma Priyanka Yadav Source Type: research

Antimicrobial susceptibility of Leptospira spp. isolated from environmental, human and animal sources in Malaysia
Douadi Benacer, Siti Nursheena Mohd Zain, Peck Toung Ooi, Kwai Lin ThongIndian Journal of Medical Microbiology 2017 35(1):124-128 Leptospirosis is a zoonosis with worldwide distribution caused by pathogenic spirochetes of the genus Leptospira. The aim of this study was to evaluate the susceptibility of isolates obtained from different hosts. A total of 65 Leptospira isolates from humans (n = 1), zoonoses (rat, n = 60; dog, n = 1; swine, n = 1) and environment (n = 2) were tested against six antibiotics. All the isolates were resistant to trimethoprim and sulphamethoxazole and had high MIC toward chlora...
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Douadi Benacer Siti Nursheena Mohd Zain Peck Toung Ooi Kwai Lin Thong Source Type: research

Coagulase-negative staphylococci: Emerging pathogen in central nervous system shunt infection
Preeti Lata Bhatia, Sunil Lilani, Ritesh Shirpurkar, Chhaya Chande, Shrikant Joshi, Abhay ChowdharyIndian Journal of Medical Microbiology 2017 35(1):120-123 Central nervous system (CNS) shunts are commonly used to treat patients with hydrocephalus. Its placement is associated with increased risk of infection. The study was intended to evaluate infection rate associated with CNS shunt surgeries and identify risk factors for shunt infection. The frequency and characterisation of aetiological agents along with their antibiotic resistance pattern were also studied. A prospective study of 86 patients who underwent 97 surgeries...
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Preeti Lata Bhatia Sunil Lilani Ritesh Shirpurkar Chhaya Chande Shrikant Joshi Abhay Chowdhary Source Type: research

Strengths and limitations of various screening methods for carbapenem-resistant Enterobacteriaceae including new method recommended by clinical and laboratory standards institute, 2017: A tertiary care experience
Agila Kumari Pragasam, Balaji Veeraraghavan, Yamuna Devi Bakthavatchalam, Radha Gopi, Raziya Fathima AslamIndian Journal of Medical Microbiology 2017 35(1):116-119 Carbapenemase-mediated carbapenem resistance is a major concern across the world. Rapid detection of carbapenemase-producing organisms is of great importance in clinical settings. However, it is essential to have a test with good sensitivity and specificity. The aim of the study was to compare the performance of RAPIDEC® CARBA NP and modified carbapenem inactivation method (mCIM) recommended by Clinical and Laboratory Standards Institute guideline 2017. A ...
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Agila Kumari Pragasam Balaji Veeraraghavan Yamuna Devi Bakthavatchalam Radha Gopi Raziya Fathima Aslam Source Type: research

Multiplex polymerase chain reaction for the detection of high-risk-human papillomavirus types in formalin-fixed paraffin-embedded cervical tissues
This study aimed to develop a multiplex polymerase chain reaction (PCR) for identification of HPV types 16 and 18 along with the beta globin gene in formalin-fixed and paraffin-embedded cervical biopsy specimens. A total of 59 samples from patients with cervical abnormalities were tested. HPV 16 positivity was 50% in cervical cancers and 52.9% in cervical intraepithelial neoplasia. Our multiplex PCR protocol can be used as a simple and cost-effective tool for high-risk-HPV detection in cervical cancer screening programmes. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Mini P Singh Nalini Gupta T Deepak Archit Kumar Radha Kanta Ratho Source Type: research

Mutation pattern in the genome of Neisseria gonorrhoeae and its association with multidrug-resistant isolates from Delhi, India
Divya Sachdev, Indu Kumari, Manju Bala, Vineet Kumar, Daman SalujaIndian Journal of Medical Microbiology 2017 35(1):109-112 Mutations in PenA, PorB, MtrE and MtrR genes responsible for antimicrobial resistance were checked in 27 drug-resistant clinical isolates of Neisseria gonorrhoeae (NG). Phenotype PIB (88.88%) and mutation at G120 and A121 positions of porB were recurrent. N122K, a novel mutation, was observed in PorB in three resistant isolates. Substitution H105Y in MtrR was widespread (37% of clinical isolates). The presence of a novel mutation (L33V), along with G45D mutation in MtrR, was associated with l...
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Divya Sachdev Indu Kumari Manju Bala Vineet Kumar Daman Saluja Source Type: research

Characterisation of the human oral microbiome in patients with coronary artery disease using next-generation sequencing of 16SrRNA amplicons
Conclusion: A comparison of the oral microbiome in patients with CAD and DC shows a similarity in the composition of the oral microbiota with variations in the proportion of a few genera. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Thangam Menon Sathya Narayanan Gopalakrishnan Rayvathy Balasubramanian Stalin Roy Justin Source Type: research

Prevalence of pneumococcal serotypes in adults & #8805;50 years of age
Conclusions: Our study shows different antibiotic susceptibility patterns of S. pneumoniae as compared to other neighbouring regions in Asia. The modest coverage of S. pneumoniae serotypes by PPV23 vaccine and prevalence of diverse NVTs in adult population make it a challenging task to recommend further changes in the future vaccine. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Chand Wattal Neeraj Goel SP Byotra Source Type: research

Evaluation of loop-mediated isothermal amplification assay for rapid diagnosis of Acanthamoeba keratitis
Conclusion: PCR and LAMP assays targeting 18S rDNA gene were found particularly suitable for a rapid and accurate diagnosis of AK. LAMP assay takes 2–3 h lesser than PCR, and thus offers a rapid, highly sensitive and specific, simple and affordable diagnostic modality for patients suspected of AK, especially in resource limited settings (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Abhishek Mewara Sumeeta Khurana Shakila Yoonus Kirti Megha Parveen Tanwar Amit Gupta Rakesh Sehgal Source Type: research

Matrix-assisted laser desorption ionisation time-of-flight mass spectrometry rapid detection of carbapenamase activity in Acinetobacter baumannii isolates
Conclusion: MALDI TOF is a promising tool in the field of diagnostic microbiology that has the ability to transfer identification and antimicrobial susceptibility testing time from days to hours. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Noha Abouseada May Raouf Eman El-Attar Pacinte Moez Source Type: research

Bacterial and fungal biofilm formation on contact lenses and their susceptibility to lens care solutions
Conclusion: This study showed the importance of selecting the appropriate lens cleaning solution to prevent biofilm production on contact lenses. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Siddharth Kackar Ethel Suman M Shashidhar Kotian Source Type: research

Human papillomavirus and Chlamydia trachomatis infection in gyneco-obstetric outpatients from a mexican hospital
Conclusions: More than 25% of the population was infected with either agent. We successfully used in-house molecular methodologies for diagnosis and typing, showing HPV and C. trachomatis prevalence consistent to previous reports. Concomitant infections were found, HPV high-risk types were involved in half of these cases, representing a higher risk. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Laura Conde-Ferr & #225;ez Jorge Ramiro Carrillo Mart & #237;ez Guadalupe Ayora-Talavera Mar & #237;a del Refugio Gonz & #225;lez Losa Source Type: research

Detection of ofloxacin resistance by nitrate reductase assay in Mycobacterium tuberculosis isolates from extrapulmonary tuberculosis
Conclusions: NRA is a specific and sensitive method for detection of OFX resistance in resource-restricted settings. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Neeta Shrivastava Reena Set Sheetal Bankar Jayanthi Shastri Source Type: research

Characterisation of antimicrobial resistance in Salmonellae during 2014 & #8211;2015 from four centres across India: An ICMR antimicrobial resistance surveillance network report
Conclusions: Enteric fever is one such infection which poses challenges in antimicrobial resistance. Hence, continuous surveillance is important to track bacterial resistance and to treat infections in a cost-effective manner. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Sushila Dahiya Priyanka Sharma Bhavana Kumari Sangeeta Pandey Rooma Malik Neelam Manral Balaji Veeraraghavan Agila Kumari Pragasam Pallab Ray Vikas Gautam Sujata Sistla Subhash Chandra Parija Kamini Walia Vinod Ohri Bimal Kumar Das Seema Sood Arti Kapil Source Type: research

Prevalence and genetic mechanisms of antimicrobial resistance in Staphylococcus species: A multicentre report of the indian council of medical research antimicrobial resistance surveillance network
Conclusion: There were localised differences in the prevalence of resistance between the centres. The efficacy of the anti-MRSA antimicrobials was very high; however, almost all these antimicrobials showed evidence of creeping MIC. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Sunanda Rajkumar Sujatha Sistla Meerabai Manoharan Madhan Sugumar Niveditha Nagasundaram Subhash Chandra Parija Pallab Ray Yamuna Devi Bakthavatchalam Balaji Veeraraghavan Arti Kapil Kamini Walia VC Ohri Source Type: research

Biofilm formation capability of enterococcal strains causing urinary tract infection vis-a-vis colonisation and correlation with enterococcal surface protein gene
Shubha Garg, Balvinder Mohan, Neelam TanejaIndian Journal of Medical Microbiology 2017 35(1):48-52 Background: Data regarding differences in biofilm formation among urinary isolates of enterococci causing nosocomial infection versus asymptomatic colonisation is lacking. Conflicting data are available for the role of enterococcal surface protein (esp) gene in the development of enterococcal biofilms. Materials and Methods: A total of 50 (25 each of asymptomatic bacteriuria and urinary tract infection (UTI) isolates were collected from admitted patients who had nosocomial acquisition of enterococci in urine culture (≥...
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Shubha Garg Balvinder Mohan Neelam Taneja Source Type: research

Screening of invasive fungal infections by a real-time panfungal (pan-ACF) polymerase chain reaction assay in patients with haematological malignancy
Conclusions: The panfungal (Pan-ACF) real-time PCR assay can detect common fungal genera and it may be used as an adjunct to conventional methods for screening of IFI. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Malini Rajinder Capoor Shikha Puri Hitesh Raheja Ritin Mohindra Dinesh Kumar Gupta Pradeep Kumar Verma Ranadeep Chowdhary Source Type: research

Occurrence of enteric parasitic infections among HIV-infected individuals and its relation to CD4 T-cell counts with a special emphasis on coccidian parasites at a tertiary care centre in South India
Conclusions: Coccidian parasites continue to be the most common aetiological agent of diarrhoea among patients with HIV. The increasing trend of positivity of both cystoisosporiasis and cryptosporidiosis over the study period and the high positivity of cryptosporidiosis in patients with lower CD4+ T-cell counts are issues of serious concern. The findings call for the need for the early diagnosis of coccidian parasites and appropriate intervention among HIV-infected patients. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Chinnambedu R Swathirajan Ramachandran Vignesh Ambrose Pradeep Sunil S Solomon Suniti Solomon Pachamuthu Balakrishnan Source Type: research

Prevalence and characterization of rotaviruses in children hospitalized for diarrheal disease in a tertiary care hospital, Pune
Conclusion: Genotypes found in circulation are not present in the currently used vaccine. Thus, an emergence of newer genotypes over a period calls for the continued surveillance and genomic characterisation of rotaviruses to improve the vaccine efficacy. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Sae Satish Pol Ashwini Kacharu Dedwal Sujata Sudhir Ranshing Shobha Dattatray Chitambar Sushma Narayan Pednekar Renu Satish Bharadwaj Source Type: research

Spoligotype defined lineages of Mycobacterium tuberculosis and drug resistance: Merely a casual correlation ?
Nikita Panwalkar, Devendra S Chauhan, Prabha DesikanIndian Journal of Medical Microbiology 2017 35(1):27-32 Drug-resistant tuberculosis (TB) is a major challenge to TB control strategy worldwide. Analysis of genetic polymorphism among drug resistant Mycobacterium tuberculosis (MTB) strains may help provide some insight into the transmission dynamics of these strains. Spoligotyping is a widely used technique to identify genetic polymorphism, based on 43 known spacers interspersed between direct repeat regions. Considerable work has been done in various parts of the world using this technique to identify and analyse the pol...
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Nikita Panwalkar Devendra S Chauhan Prabha Desikan Source Type: research

Molecular typing of Chlamydia trachomatis: An overview
Jyoti Rawre, Deepak Juyal, Benu DhawanIndian Journal of Medical Microbiology 2017 35(1):17-26 Urogenital infection due to Chlamydia trachomatis (CT) is one of the most common bacterial sexually transmitted infections (STIs) and is a major public health problem worldwide. Molecular characterisation of CT is important for understanding the pathophysiological mechanisms of chlamydial disease and its transmission dynamics in sexual networks. Traditionally, strain typing of CT was based on serotyping methods characterising the major outer membrane protein (MOMP). With the advent of polymerase chain reaction and sequencing the ...
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Jyoti Rawre Deepak Juyal Benu Dhawan Source Type: research

Global eradication of measles: Are we poised ?
Raghavendra D Kulkarni, GS Ajantha, Aithal R Kiran, KR PravinchandraIndian Journal of Medical Microbiology 2017 35(1):10-16 Measles, a highly infectious viral disease is the next target for eradication following poliovirus. Decades of experience with highly effective vaccination has invigorated us to take on this virus. The task is not only Titanic but is laced with intricate issues. Recently, an outbreak of fever with rash occurred on a tertiary care teaching hospital campus and was confirmed serologically as measles outbreak by IgMELISA. Therefore, we searched the literature related to outbreaks, transmission of the mea...
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Raghavendra D Kulkarni GS Ajantha Aithal R Kiran KR Pravinchandra Source Type: research

Systematic reviews of diagnostic tests: A primer
Thambu David, Prathap TharyanIndian Journal of Medical Microbiology 2017 35(1):8-9 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Thambu David Prathap Tharyan Source Type: research

Emerging challenges and opportunities in medical microbiology
Rajesh BhatiaIndian Journal of Medical Microbiology 2017 35(1):4-7 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Rajesh Bhatia Source Type: research

Global response to combat antimicrobial resistance
Poonam Khetrapal SinghIndian Journal of Medical Microbiology 2017 35(1):1-3 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - March 16, 2017 Category: Microbiology Authors: Poonam Khetrapal Singh Source Type: research

Erratum: Endemic Indian clones of Klebsiella pneumoniae harbouring New Delhi metallo beta lactamase 1 on a hybrid plasmid replicon type: A case of changing New Delhi metallo beta lactamase plasmid landscapes in India ?
Indian Journal of Medical Microbiology 2016 34(4):567-567 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - December 8, 2016 Category: Microbiology Source Type: research

Polymyxin Nordmann/Poirel test for rapid detection of polymyxin resistance in Enterobacteriaceae: Indian experience
Yamuna Devi Bakthavatchalam, Balaji Veeraraghavan, Purva Mathur, Swathi Purighalla, Vijay Samuel RichardIndian Journal of Medical Microbiology 2016 34(4):564-565 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - December 8, 2016 Category: Microbiology Authors: Yamuna Devi Bakthavatchalam Balaji Veeraraghavan Purva Mathur Swathi Purighalla Vijay Samuel Richard Source Type: research

Medical Council of India circular on research publications: Flaring up the fire
D Juyal, V Thawani, S Thaledi, B DhawanIndian Journal of Medical Microbiology 2016 34(4):563-564 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - December 8, 2016 Category: Microbiology Authors: D Juyal V Thawani S Thaledi B Dhawan Source Type: research

Stamp & #39;s modified Ziehl & #8211;Neelsen staining for Brucella: Beware of the first impressions
K Tilak, VK Eshwara, C Tellapragada, C MukhopadhyayIndian Journal of Medical Microbiology 2016 34(4):561-562 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - December 8, 2016 Category: Microbiology Authors: K Tilak VK Eshwara C Tellapragada C Mukhopadhyay Source Type: research

Gonococcal opa gene as a diagnostic target for nucleic acid amplification tests in Indian Population
R Verma, N Mahajan, S SoodIndian Journal of Medical Microbiology 2016 34(4):560-561 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - December 8, 2016 Category: Microbiology Authors: R Verma N Mahajan S Sood Source Type: research

In vitro susceptibility of carbapenem-resistant Enterobacteriaceae to colistin: A hope at present
S Mohanty, R GaindIndian Journal of Medical Microbiology 2016 34(4):558-560 (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - December 8, 2016 Category: Microbiology Authors: S Mohanty R Gaind Source Type: research

Severe unresolving Plasmodium falciparum malaria following artemisinin combination therapy: Emergence of drug resistance in Saudi Arabia
IA Al-Zaydani, A Al-Hakami, A Kumar, SA Abdalla, M Otaif, RMA Thiqa, H Ahmed, K AlnahiliIndian Journal of Medical Microbiology 2016 34(4):553-557A 5-year-old female child presented with fever of 1-week duration after visiting a malaria endemic zone without antimalarial prophylaxis. The patient presented with respiratory distress, decreased level of consciousness and high-grade fever. An elevated parasitaemia reaching 800,000/μl was observed. Antimalarial therapy was initiated with artesunate being administered intravenous (IV) along with IV clindamycin. Contrary to the expectations, there was no resolution of fever. F...
Source: Indian Journal of Medical Microbiology - December 8, 2016 Category: Microbiology Authors: IA Al-Zaydani A Al-Hakami A Kumar SA Abdalla M Otaif RMA Thiqa H Ahmed K Alnahili Source Type: research

Successful treatment of primary cerebral mucormycosis: Role of microbiologist
We report a 56-year-old woman diagnosed to have fungal abscess who recovered completely following amphotericin B treatment. She presented with weakness of the right hand, deviation of mouth to left and aphasia for 2 days. Computed tomography of the brain revealed a left frontal capsuloganglionic hypodense lesion. Stereotactic biopsy was performed, and microbiological confirmation of non-septate fungal hyphae from pus from aspirate within 2 h helped initiate timely and appropriate treatment leading to cure. Histopathology and culture later confirmed mucormycosis. (Source: Indian Journal of Medical Microbiology)
Source: Indian Journal of Medical Microbiology - December 8, 2016 Category: Microbiology Authors: KK Benachinmardi P Rajalakshmi HB Veenakumari RD Bharath V Vikas A Mahadevan S Nagarathna Source Type: research