Predicting Biochemical Failure in Irradiated Patients With Prostate Cancer by Tumour Volume Measured by Multiparametric MRI
Conclusion: GTV, defined using mpMRI, provides incremental prognostic value for BRFS, independent of established risk factors. This supports the implementation of imaging-based GTV for risk-stratification, although further validation is needed. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: OERTHER, B., BUREN, M. V., KLEIN, C. M., KIRSTE, S., NICOLAY, N. H., SPRAVE, T., SPOHN, S., GUNASHEKAR, D. D., HAGELE, L., BIELAK, L., BOCK, M., GROSU, A.-L., BAMBERG, F., BENNDORF, M., ZAMBOGLOU, C. Tags: Clinical Studies Source Type: research
Dominant Antibiotic Consumption Patterns Might Be Associated With the Prevalence of Multiple Sclerosis in European Countries
Conclusion: Countries, with high consumption of narrow spectrum penicillin and tetracycline, experience a higher prevalence of MS than other countries. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: TERNAK, G., BERENYI, K., MAROVICS, G., SUMEGI, A., FODOR, B., NEMETH, B., KISS, I. Tags: Clinical Studies Source Type: research
Risk Factors for Delayed Elimination of Methotrexate in Children, Adolescents and Young Adults With Osteosarcoma
Conclusion: Knowing the factors associated with delayed elimination of MTX could lead to safer and optimized chemotherapy for patients with osteosarcoma. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: MISAKA, K., SUGA, Y., STAUB, Y., TSUBATA, A., SHIMADA, T., SAI, Y., MATSUSHITA, R. Tags: Clinical Studies Source Type: research
Clinical Significance of Prognostic Nutritional Index in the Treatment of Esophageal Squamous Cell Carcinoma
Conclusion: Pre-Tx PNI is an independent prognostic factor irrespective of NAC. Patients in whom the post-NAC PNI can be improved have a high probability of obtaining a good prognosis. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: TAKAO, K., KONISHI, H., FUJIWARA, H., SHIOZAKI, A., SHODA, K., KOSUGA, T., KUBOTA, T., ARITA, T., MORIMURA, R., MURAYAMA, Y., KURIU, Y., IKOMA, H., NAKANISHI, M., OKAMOTO, K., OTSUJI, E. Tags: Clinical Studies Source Type: research
Impact of Hormone Receptor Status on the Behaviour of HER2+ Breast Cancer
Conclusion: Increased OS rates were found in several subgroups of patients with HR+/HER2+ tumours compared to those with HR-/HER2+ tumours. Better outcomes of HR+/HER2+ patients were only observed in the first four/five years of follow-up, and the differences disappeared over time. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: KOLAROVA, I., DUSEK, L., RYSKA, A., ODRAZKA, K., DOLEZEL, M., VANASEK, J., MELICHAR, B., PETERA, J., BUCHLER, T., VOSMIK, M., PETRAKOVA, K., TERAROVA, P., VILASOVA, Z., JARKOVSKY, J. Tags: Clinical Studies Source Type: research
A Prospective Evaluation of Tru-Cut Biopsy and Fine-needle Aspiration Cytology in Male Breast Cancer Detection
Conclusion: FNAC leads to a significantly higher number of inadequate samplings and seems to be subject to increased DCIS misdiagnoses. TCNB correlated better to the final histological report. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: PISTOLESE, C. A., PERRETTA, T., CLARONI, G., ANEMONA, L., SERVADEI, F., COLLURA, A., CENSI, M., MATERAZZO, M., PELLICCIARO, M., LAMACCHIA, F., VANNI, G. Tags: Clinical Studies Source Type: research
The (Eternal) Debate on Microwave Ablation Versus Radiofrequency Ablation in BCLC-A Hepatocellular Carcinoma
Conclusion: MWA and RFA are effective and safe techniques in early stage, BCLC-A, HCCMWA resulted in better 1-year OS, although this benefit was not confirmed in the 3-year analysis. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: RICCI, A. D., RIZZO, A., BONUCCI, C., TAVOLARI, S., PALLONI, A., FREGA, G., MOLLICA, V., TOBER, N., MAZZOTTA, E., FELICANI, C., SERRA, C., BRANDI, G. Tags: Clinical Studies Source Type: research
Capecitabine Plus Bevacizumab for Cardiac Metastasis of Sigmoid Colon Cancer: Case Report and Literature Review
Conclusion: Cardiac right ventricular metastasis from CRC can be controlled by capecitabine plus bevacizumab. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: HIROI, S., MIGUCHI, M., IKEDA, S., NAKAHARA, H., SHINOZAKI, K., NISHISAKA, T., EGI, H., ITAMOTO, T. Tags: Clinical Studies Source Type: research
Robotic Incisional Hernia Repair After Robotic-assisted Radical Prostatectomy (RARP): A 3-port Approach
Conclusion: RIHR is a feasible surgical method that is not inferior to the traditional open or laparoscopic repair. Furthermore, RIHR can possibly lessen the burden of both the surgeon and patient. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: OU, H.-C., HUANG, L.-H., CHANG, K.-H., OU, Y.-C., TUNG, M.-C., WENG, W.-C., HSU, C.-Y., LIN, Y.-S., LU, C.-H., TSAO, T.-Y. Tags: Clinical Studies Source Type: research
Tolerability and Adverse Events of Adjuvant Chemotherapy for Rectal Cancer in Patients With Diverting Ileostomy
Conclusion: Completion rate of ACT in patients with diverting ileostomy was lower than that of colorectal cancer patients in the previous studies. UFT/LV may be a more tolerable regimen than Capecitabine or CAPOX in colorectal cancer patients with diverting ileostomy. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: TAKAHASHI, J., TSUJINAKA, S., MAEMOTO, R., MIYAKURA, Y., SUZUKI, K., FUKUDA, R., SAKIO, R., MACHIDA, E., RIKIYAMA, T. Tags: Clinical Studies Source Type: research
Treatment Outcome of the Combination Therapy of High-dose rate Intracavitary Brachytherapy and Intensity-modulated Radiation Therapy With Central-shielding for Cervical Cancer
Conclusion: IMRT of WPRT and WPRT-CS given in combination with HDR-ICBT was a feasible therapy resulting in good disease control and tolerance in patients with UCC. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: MUKAI, Y., MINAGAWA, Y., INOUE, H., SATO, A., MATSUI, K., FUKUDA, T., ONUMA, K., HONGO, H., SHIRATA, R., NAGATA, H., HASHIMOTO, H., INOUE, T., HATA, M., OMURA, M. Tags: Clinical Studies Source Type: research
Genomic Profiling and Clinicopathological Characteristics of Neuroendocrine Tumors of the Lung in East Asian Patients
Conclusion: The mutational status of TP53 and RB1 was significantly associated with NET subtypes in East Asian patients. Targeted therapy or immunotherapy may serve as a treatment option in a subset of patients with high-grade NETs. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: KIM, M., CHUNG, Y. S., KIM, K. A., SHIM, H. S. Tags: Clinical Studies Source Type: research
Impact of Surgical Resection on Metachronous Metastases of Colorectal Cancer According to Tumor Doubling Time
Conclusion: Surgery is recommended for resectable metastases, especially in patients with liver and peritoneal metastases with long DT. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: MIYAKE, H., MURONO, K., KAWAI, K., NOZAWA, H., MAKI, H., HASEGAWA, K., NAKAJIMA, J., ISHIHARA, S. Tags: Clinical Studies Source Type: research
Risk Factors for Severe Complications in Ovarian Cancer Surgery
Conclusion: In EOC patients age, smoking and the duration of surgery have significant impact on the postoperative course. Only the duration of surgery can be positively influenced by a well-trained EOC team. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: EGGER, E. K., KOHLS, N., STOPE, M. B., CONDIC, M., KEYVER-PAIK, M.-D., KONSGEN, D., HILBERT, T., KLASCHIK, S., EXNER, D., VILZ, T., MUSTEA, A. Tags: Clinical Studies Source Type: research
The Systemic Immune-Inflammation Index Predicts Clinical Outcomes in Kidney Transplant Recipients
Conclusion: SII demonstrated limited utility as an independent predictor of outcomes after KTx. However, in combination with other clinically relevant parameters, SII is a useful predictor of post-KTx prognosis. Validation of this novel inflammatory biomarker in a multi-institutional study is needed to further elucidate its practical applications in transplantation. (Source: In Vivo)
Source: In Vivo - November 3, 2020 Category: Research Authors: HALPERN, S. E., MORIS, D., SHAW, B. I., KRISCHAK, M. K., OLASO, D. G., KESSELI, S. J., RAVINDRA, K., MCELROY, L. M., BARBAS, A. S. Tags: Clinical Studies Source Type: research
