Enamel Matrix Derivative in Diffusion Chamber Implanted Subcutaneously in Rat Induces Formation of Fibrous Connective Tissue Containing Abundant Blood Vessels
Conclusion: The results indicated that EMD can induce the formation of both connective tissue and blood vessels. This bioactivity may contribute to the mechanism whereby EMD induces tissue regeneration. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: YOKOSE, S., KATO, Y., MATSUMOTO, K., KLOKKEVOLD, P. R., TAKEI, H. H., KAWAZU, H., SAKAGAMI, H. Tags: Experimental Studies Source Type: research
IGF-1 Protects Neurons in the Cortex and Subventricular Zone in a Periventricular Leucomalacia Model
Conclusion: PVL increased the number of early neuronal cells in the SVZ, reducing the survival of mature neurons in the cerebral cortex; IGF-1 reversed these effects. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: KIM, D.-J., CHO, S.-Y., KIM, S.-U., JO, D.-W., HWANG, H.-I., SHIN, H.-K., JUN, Y.-H. Tags: Experimental Studies Source Type: research
High MCM6 Expression as a Potential Prognostic Marker in Clear-cell Renal Cell Carcinoma
Conclusion: A high MCM6 expression level may be a promising biomarker to predict tumor progression, metastasis, and survival in patients with ccRCC. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: JANG, N.-R., BAEK, J., KO, Y., SONG, P. H., GU, M.-J. Tags: Experimental Studies Source Type: research
Relationship Between Insulin-Receptor Substrate 1 and Langerhans Islet in a Rat Model of Type 2 Diabetes Mellitus
Conclusion: The reduction of IRS1 was weakly correlated with the destruction of Langerhans’ islets, suggesting there is an intermediate step between both parameters. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: ATMODJO, W. L., LARASATI, Y. O., JO, J., NUFIKA, R., NAOMI, S., WINOTO, I. Tags: Experimental Studies Source Type: research
Effects of Different Media on Human T Regulatory Cells Phenotype
Conclusion: Appropriate protocols of cell isolation and storage are important for providing appropriate conditions for cell growth. This is crucial when analyzing small cell populations like Tregs. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: GŁACZYNSKA, M., MACHCINSKA, M., DONSKOW-LYSONIEWSKA, K. Tags: Experimental Studies Source Type: research
Deformation of the Pelvic Arteries Caused by Pneumoperitoneum and Postural Changes in an Animal Model
Conclusion: The pelvis was useful for registering anatomical landmarks. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: KIYOMATSU, H., MA, L., WANG, J., KIYOMATSU, T., TSUKIHARA, H., KOBAYASHI, E., SAKUMA, I., ISHIHARA, S. Tags: Experimental Studies Source Type: research
Aberrant GLUT1 Expression Is Associated With Carcinogenesis and Progression of Liver Fluke-associated Cholangiocarcinoma
Conclusion: GLUT1 plays important roles in carcinogenesis and progression of liver fluke-associated CCA. Targeting GLUT1 may be a strategy for treatment of metastasis in liver fluke-associated CCA. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: THAMRONGWARANGGOON, U., SANGKHAMANON, S., SEUBWAI, W., SARANARUK, P., CHAON, U., WONGKHAM, S. Tags: Experimental Studies Source Type: research
Changes in the Mineral Composition of Rat Tissues Induced by Breast Cancer and Dietary Supplementation
Conclusion: Further research using various levels of zinc and genistein in the diet should be conducted to determine how the development and progression of cancer is linked to iron content in cells and its ability to accumulate in tumour tissue. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: SKRAJNOWSKA, D., TOKARZ, A., MAKOWSKA, J., BOBROWSKA-KORCZAK, B. Tags: Experimental Studies Source Type: research
Curcumin Activates ROS Signaling to Promote Pyroptosis in Hepatocellular Carcinoma HepG2 Cells
Conclusion: Curcumin induces HspG2 cell death by increasing apoptosis and pyroptosis, and ROS play a key role in this process. This study improves our understanding of the potential anti-cancer properties of curcumin in liver cancer. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: LIANG, W.-F., GONG, Y.-X., LI, H.-F., SUN, F.-L., LI, W.-L., CHEN, D.-Q., XIE, D.-P., REN, C.-X., GUO, X.-Y., WANG, Z.-Y., KWON, T., SUN, H.-N. Tags: Experimental Studies Source Type: research
Tumor Growth Suppression With Novel Intra-arterial Chemotherapy Using Epirubicin-entrapped Water-in-oil-in-water Emulsion In Vivo
Conclusion: WOW-Epi led to tumour growth suppression in vivo. WOW does not cause toxicity to arterial vessels. WOW-Epi will be hopefully used for repeated intra-arterial chemotherapy to HCC patients in the near future. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: YANAGIE, H., FUJINO, T., YANAGAWA, M., TERAO, T., IMAGAWA, T., FUJIHARA, M., MORISHITA, Y., MIZUMACHI, R., MURATA, Y., DEWI, N., ONO, Y., IKUSHIMA, I., SEGUCHI, K., NAGATA, M., NONAKA, Y., FURUYA, Y., HISA, T., NAGASAKI, T., ARIMORI, K., NAKASHIMA, T., SU Tags: Experimental Studies Source Type: research
Sulfite Oxidase Is a Novel Prognostic Biomarker of Advanced Gastric Cancer
Conclusion: SUOX is an independent prognostic factor. Therefore, SUOX expression could also serve as a useful marker for elucidating the mechanism of gastric cancer proliferation and progression. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: YANO, Y., AKIBA, J., NAITO, Y., SADASHIMA, E., CHO, H., HISHIMA, T., YANO, H. Tags: Experimental Studies Source Type: research
Anti-metastatic Effects of Cationic KT2 Peptide (a Lysine/Tryptophan-rich Peptide) on Human Melanoma A375.S2 Cells
Conclusion: These results indicate that KT2 inhibits the migration and invasion of human melanoma cells by decreasing MMP-2 and MMP-9 expression through inhibition of FAK, uPA, MAPK, PI3K/AKT NF-kB, and RhoA–ROCK signalling pathways. These findings suggest that KT2 deserves further investigation as an anti-metastatic agent for human melanoma. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: MARAMING, P., KLAYNONGSRUANG, S., BOONSIRI, P., PENG, S.-F., DADUANG, S., RUNGSA, P., TAVICHAKORNTRAKOOL, R., CHUNG, J.-G., DADUANG, J. Tags: Experimental Studies Source Type: research
MYC Up-regulation Is a Useful Biomarker for Preoperative Neoadjuvant Chemotherapy Combined With Anti-EGFR in Liver Metastasis from Colorectal Cancer
Conclusion: MYC up-regulation in the primary CRC tissues may be a potentially useful biomarker for selecting anti-EGFR combination therapy in neoadjuvant chemotherapy for CRC with liver metastasis. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: KATO, T., MATSUHASHI, N., TOMITA, H., TAKAHASHI, T., IWATA, Y., FUKADA, M., YASUFUKU, I., SUETSUGU, T., IMAI, T., MORI, R., IMAI, H., TANAKA, Y., OKUMURA, N., HARA, A., YOSHIDA, K. Tags: Experimental Studies Source Type: research
ELF3 Overexpression as Prognostic Biomarker for Recurrence of Stage II Colorectal Cancer
Conclusion: High ELF3 expression was associated with recurrence of Stage II. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: TAKAOKA, A., ISHIKAWA, T., OKAZAKI, S., WATANABE, S., MIYA, F., TSUNODA, T., KIKUCHI, A., YAMAUCHI, S., MATSUYAMA, T., TOKUNAGA, M., UETAKE, H., KINUGASA, Y. Tags: Experimental Studies Source Type: research
Mitochondrial DNA Methylation Is Higher in Acute Coronary Syndrome Than in Stable Coronary Artery Disease
Conclusion: Our findings suggest that increased DNA methylation in the mtDLR, which translates into reduced mtDNA content, may affect the clinical phenotype of CAD. (Source: In Vivo)
Source: In Vivo - January 5, 2021 Category: Research Authors: PARK, S. H., LEE, S. Y., KIM, S. A. Tags: Experimental Studies Source Type: research
