VEGF-A Is Associated With the Degree of TILs and PD-L1 Expression in Primary Breast Cancer
Conclusion: VEGF-A expression in breast cancer may reflect PD-L1 expression in the tumor. VEGF-A may act as a negative biomarker of TILs in PD-L1-positive breast cancer. Our results suggest that VEGF-A may be predictive of immunological features and may serve as a useful biomarker for immuno-targeting therapy in patients with breast cancer. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: FUJII, T., HIRAKATA, T., KUROZUMI, S., TOKUDA, S., NAKAZAWA, Y., OBAYASHI, S., YAJIMA, R., OYAMA, T., SHIRABE, K. Tags: Clinical Studies Source Type: research
Prognostic and Clinical Implications of WNK Lysine Deficient Protein Kinase 1 Expression in Patients With Hepatocellular Carcinoma
Conclusion: In summary, WNK1 is overexpressed at the mRNA and protein levels, and correlated with poor prognosis. Thus, WNK1 expression could potentially be used as a biomarker in HCC prognosis. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: HO, Y.-J., CHANG, J., YEH, K.-T., GONG, Z., LIN, Y.-M., LU, J.-W. Tags: Clinical Studies Source Type: research
Effects of Alkalization Therapy on Chemotherapy Outcomes in Advanced Pancreatic Cancer: A Retrospective Case-Control Study
Conclusion: Alkalization therapy may enhance the effects of chemotherapy in patients with advanced pancreatic cancer. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: HAMAGUCHI, R., ITO, T., NARUI, R., MORIKAWA, H., UEMOTO, S., WADA, H. Tags: Clinical Studies Source Type: research
Clinicopathological Characteristics of Squamous Cell Carcinoma and High-grade Squamous Intraepithelial Lesions Involving Endocervical Polyps
Conclusion: The prevalence of HSIL and SCC involving ECP in our cohort was similar to the rates found in previous studies. The presence of residual HSIL in nonpolypoid cervical tissue regardless of the polypectomy margin involvement suggests that conization or hysterectomy is needed for diagnostic or treatment purposes. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: PARK, C. K., KIM, Y.-W., KOH, H. H., YOON, N., BAE, G. E., KIM, H.-S. Tags: Clinical Studies Source Type: research
Anatomical Versus Non-anatomical Resection for Hepatocellular Carcinoma, a Propensity-matched Analysis Between Taiwanese and Japanese Patients
Conclusion: AR of HCC in Japanese patients has a similar 5-year DFS and OS as NAR of HCC in Taiwanese patients. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: HUANG, S.-W., CHU, P.-Y., ARIIZUMI, S., LIN, C. C.-W., WONG, H. P., CHOU, D.-A., LEE, M.-T., WU, H.-J., YAMAMOTO, M. Tags: Clinical Studies Source Type: research
Biomarker Analyses in Patients With Advanced Solid Tumors Treated With the LAT1 Inhibitor JPH203
Conclusion: BCAAs and BMI are useful predictors of the efficacy of JPH203, which shows promising activity against BTC. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: OKANO, N., HANA, K., NARUGE, D., KAWAI, K., KOBAYASHI, T., NAGASHIMA, F., ENDOU, H., FURUSE, J. Tags: Clinical Studies Source Type: research
Intensity-modulated Radiation Therapy for Lymph Node Oligo-recurrence
Conclusion: IMRT may provide a safe and effective treatment for patients with LN oligo-recurrence. Tumor dose-escalation sparing normal tissue using IMRT technology may improve the OS and in-field PFS. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: SATO, A., OMURA, M., MINAGAWA, Y., MATSUI, K., SHIRATA, R., HONGO, H., HASHIMOTO, H., MISUMI, T., INOUE, T., HATA, M. Tags: Clinical Studies Source Type: research
Tau, S100B and NSE as Blood Biomarkers in Acute Cerebrovascular Events
Conclusion: For the diagnosis of TIA vs. AIS, blood T-tau and S100B concentrations discriminated only modestly. Additionally, groups were not separable after measuring of T-tau and S100B levels in the blood. T-tau and S100B concentrations correlated with the infarct size, but were not alone predictive for functional outcome at 3 months. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: ONATSU, J., VANNINEN, R., JAKALA, P., MUSTONEN, P., PULKKI, K., KORHONEN, M., HEDMAN, M., HOGLUND, K., BLENNOW, K., ZETTERBERG, H., HERUKKA, S.-K., TAINA, M. Tags: Clinical Studies Source Type: research
Older Age Is Associated With Better Compliance With Follow-up in Taiwan After Functional Endoscopic Sinus Surgery
Conclusion: In contrast to the US, older patients in Taiwan have better compliance in postoperative follow-up, while younger ones require more education on the importance of follow-up. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: TSAI, T., SHIH, L.-C., LEE, I. T., NG, T.-Y., WANG, J.-Y., HSU, C.-L., BAU, D.-T., TAI, C.-J. Tags: Clinical Studies Source Type: research
Calf Circumference as a Useful Predictor of Sarcopenia in Patients With Liver Diseases
Conclusion: CC can be helpful for predicting sarcopenia in CLDs. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: NISHIKAWA, H., YOH, K., ENOMOTO, H., IWATA, Y., SAKAI, Y., KISHINO, K., SHIMONO, Y., IKEDA, N., TAKASHIMA, T., AIZAWA, N., TAKATA, R., HASEGAWA, K., KORIYAMA, T., YURI, Y., NISHIMURA, T., NISHIGUCHI, S., IIJIMA, H. Tags: Clinical Studies Source Type: research
Sarcopenia and Frailty in Chronic Liver Damage: Common and Different Points
Conclusion: Sarcopenia and frailty in CLD should be separately evaluated. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: NISHIKAWA, H., YOH, K., ENOMOTO, H., IWATA, Y., SAKAI, Y., KISHINO, K., SHIMONO, Y., IKEDA, N., TAKASHIMA, T., AIZAWA, N., TAKATA, R., HASEGAWA, K., KORIYAMA, T., YURI, Y., NISHIMURA, T., NISHIGUCHI, S., IIJIMA, H. Tags: Clinical Studies Source Type: research
Arteriovenous Loops Enable Free Tissue Transfer With Otherwise Inadequate Local Donor and Recipient Vessels
Conclusion: We successfully reconstructed complex defects with poor recipient vessels using arteriovenous loops or bypass surgery and free flaps. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: TREMP, M., ORANGES, C. M., WOLFF, T., BARANDUN, M., FULCO, I., ECKARDT, H., SCHAEFER, D. J., KALBERMATTEN, D. F. Tags: Clinical Studies Source Type: research
Lingual Mandibular Bone Depression
Conclusion: LMBD is a developmental disorder of the mandible and only rarely of pathological importance. Imaging the lesion with cross-sectional images is preferable to using plain X-ray projections. In some cases, surgical exploration is essential for diagnosis. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: FRIEDRICH, R. E., BARSUKOV, E., KOHLRUSCH, F. K., ZUSTIN, J., HAGEL, C., SPETH, U., VOLLKOMMER, T., GOSAU, M. Tags: Clinical Studies Source Type: research
Fluoroscopic Intraoperative Images Produce Higher Image Quality and Decrease Total Radiation Exposure Compared to Radiographic X-ray Images in Patients After Primary Total Knee Arthroplasty
Conclusion: We observed significantly better image quality in fluoroscopic images than in radiographic X-ray images. The observed radiation exposure is lower than those expected for radiographic X-ray images. We conclude that fluoroscopic images can produce higher image quality and decreased radiation exposure. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: GRAULICH, T., GERHARDY, J., ORGEL, M., OMAR-PACHA, T., OMAR, M., KRETTEK, C., GUENTHER, D. Tags: Clinical Studies Source Type: research
Hip Arthroplasty Following Subtotal Sacrectomy for Chordoma
Conclusion: The results of this study indicate that hip arthroplasty is a durable treatment option for patients with metastatic disease or coxarthrosis following subtotal sacrectomy for chordoma. (Source: In Vivo)
Source: In Vivo - August 30, 2020 Category: Research Authors: CLAXTON, M. R., SHIRLEY, M. B., JOHNSON, J. D., PERRY, K. I., ROSE, P. S., HOUDEK, M. T. Tags: Clinical Studies Source Type: research
