Oral metastasis of angiosarcoma of the bladder: A case report.
This study describes case of a 28 year-old male patient presenting a symptomatic mouth lesion. The lesions exhibited erythematous and ulcerative surface and the incisional biopsy was done followed by histopathological analysis. Was necessary a immunohistochemical panel (AE1/AE3, CK7, CK9, CK10, CK20, s-100, HMB-45, desmine, actin, Factor VIII, CD-34, vimentin and CD-31) to establish the definitive diagnosis of angiosarcoma.
Discussion: Angiosarcoma is a rare tumor in the oral cavity, especially in cases of metastasis of a tumor found in the bladder. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Reliability of SPECT-CT lymphoscintigraphy compared to PET-CT for uncommon cancer cells migration in initially N0 velum neoplasia.
Conclusions
This event shows that lymphoscintigraphy combined to a SPECT-CT can predict the uncommon lymphatic migration in velum neoplasia. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Juvenile psammomatoid ossifying fibroma of the paranasal sinuses: A report of two cases.
We report two cases in female, first case of fronto-ethmiod sinus and second one of maxillary sinus. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Susceptibility to cancer of the first-degree relatives of HNSCC patients being tobacco consumers and carrying both GSTM1-GSTT1 null genotypes.
Conclusion: Our study suggests thatGSTM1 and GSTT1 null genotypes and tobacco consumption increase the risk of HNSCC. Furthermore, it revealed that the first-degree relatives of HNSCC patients highly susceptible to cancer if they carry both GSTM1 and GSTT1 null genotype and as well expose to tobacco. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Carotid cavernous fistula: A rare complication of maxillofacial trauma.
Conclusion:This paper emphasizes the need for early diagnosis and prompt treatment to prevent loss of visual function in patients with carotid cavernous fistula. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Phase II Trial of curcumin in advanced head and neck cancer treatment.
Conclusions: The present study indicates the therapeutic potential of curcumin and piperine in the palliative treatment of advance head and neck cancer as a cost-effective substitute. Further studies on similar line seem warranted. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Oral lipoma: Many features of a rare oral benign neoplasm.
We report an unusual large-sized lipomatous tumor located on the left side of floor-of-mouth, one of the rarest sites of intraoral lipoma. The final diagnosis of the lesion was fibrolipoma. The unusual characteristics of this case report were the large-sized dimensions of the neoplasm, which were 3 cm along the main diameter, and the histological subtype which is not common among the lipomas of the floor-of-mouth and of the oral cavity in general. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Metformin and oral squamous cell carcinoma?
Conclusion
A lower prevalence of oral cancer was found in diabetic patients being treated with metformin, but further studies need to be performed with a larger population. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Asymptomatic renal metastasis from laryngeal primary: A common malignancy with uncommon pattern of relapse.
Conclusion: This case report underscores the importance of awareness of unusual pattern of relapse in carcinoma larynx. Patients of carcinoma larynx should be kept onperiodicfollow-up and appropriate investigations should be done expeditiously on suspicion of recurrence. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Impact of EPA nutritional approach on cachexic patients with advanced hypopharyngeal cancer treated by induction chemotherapy.
ConclusionIn patients with hypopharyngeal cancer who experienced malnutrition after induction chemotherapy, EPA nutritional treatment significantly improved the cachexia and therefore made it possible to conduct radical treatment. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Head and neck squamous cells carcinoma, DNMT3B gene and folate pathway: A review.
The head and neck cancer includes the oral cavity (40%), pharynx (25%) and larynx (15%), and is currently considered the fifth most common type in the world and is associated with a high mortality rate when diagnosed in advanced stages. The most common histological type (90% of cases) is squamous cell carcinoma. The main risk factors include the consumption of tobacco and alcohol, viral infections and deficiencies or imbalances of vitamins and micronutrients such as folate. Accumulative genetic alterations have been associated with phenotypic progression of SCCHN, resulting in the inactivation of several tumor suppressor g...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Expression of excision repair cross-complementation group 1 (ERCC1), ribonucleotide reductase M1 (RRM1) and class III beta-tubulin in head and neck carcinoma and its clinical significance.
Conclusions:Unlike lung carcinoma, expression of ERCC1 or RRM1 did not correlate with clinical parameters or HPV status. However, p16 and TUBB3 might be useful predictive biomarkers in HNCa. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Apoptosis and cell surface GRP78 expression in benign and malignant parotid gland tumors.
Conclusions:This study is the first report describing cell surface GRP78 expression in parotid salivary tumor. The evidence of high surface GRP78expression in malignant parotid tissue in contrast to the benign tumor might add a diagnostic tool and serve as a future target for treatment of malignant parotid tumors. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Clival chordoma presenting as sphenoid sinus mass.
We present a case of 40 year female with complaint of headache, intermittent vomiting & diminution of vision. CECT Paranasal sinus suggested the possibility of Sphenoid sinus malignancy or metastases was suggested.A functional endoscopy sinus surgery was done and the mass was excised and sent for histopathological examination. Tumor cell were pleomorphic with hyperchromatic nuclei and vacuolated cytoplasm in myxoid background. Immunohistochemically cells were reactive for Cytokeratin, Epithelial membrane antigen. Final diagnosis of Chordoma was made.The purpose of this case report is to add a rare tumor in females to t...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Multiple primary melanomas versus single melanoma of head and neck: A comparison of genetic, diagnostic and therapeutic implications.
Single primary and multiple primary melanomas of the head and neck region may be confused at first glance because of the common clinical and dermoscopic patterns. An inaccurate diagnosis may lead the clinician to a wrong diagnostic and therapeutic pathway because multiple primary melanomas occurring in familial or sporadic settings are often involved in individual cancer susceptibility. We investigated clinical, demographic, histological and survival differences between multiple primary melanomas and single melanoma occurring in head and neck region.
A retrospective analysis of medical and histologic records from 217 mel...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
