Peltonen JK, Helppi HM, P ääkkö P, Turpeenniemi-Hujanen T, Vähäkangas KH. p53 in head and neck cancer: functional consequences and environmental implications of TP53 mutations. Head Neck Oncol. 2010 Dec 15;2:36.
Conclusions
Our study contributes to the knowledge of cumulative chemical exposure and p53 aberrations in head and neck cancer, an area where literature is scarce. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - July 21, 2016 Category: Cancer & Oncology Source Type: research
Jensen AD, Bergmann ZP, Garcia-Huttenlocher H, Freier K, Debus J, M ünter MW. Cetuximab and radiation for primary and recurrent squamous cell carcinoma of the head and neck (SCCHN) in the elderly and multi-morbid patient: a single-centre experience. Head Neck Oncol. 2010 Nov 26;2:34.
Conclusion
RIT is a feasible treatment option for elderly and multi-morbid patients with promising therapeutic activity. Long-term disease control can also be achieved in patients receiving RIT for re-irradiation. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - July 21, 2016 Category: Cancer & Oncology Source Type: research
Silveira AP, Gon çalves J, Sequeira T, Ribeiro C, Lopes C, Monteiro E, Pimentel FL. Patient reported outcomes in head and neck cancer: selecting instruments for quality of life integration in clinical protocols. Head Neck Oncol. 2010 Oct 31;2:32.
Conclusions
This study emphases the importance in selecting the appropriate tool as a critical success factor in implementing routine Health Related Quality of Life assessment in clinical practice. This decision assumes particularly importance when utilization of results in real time and integr ation into clinical protocols are considered. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - July 21, 2016 Category: Cancer & Oncology Source Type: research
Kruse AL, Bredell M, Luebbers HT, Gr ätz KW. Head and neck cancer in the elderly: a retrospective study over 10 years (1999 - 2008). Head Neck Oncol. 2010 Oct 5;2:25.
Conclusion
The group of patients with head and neck cancer who were older than 70 years was characterized by a higher portion of female patients, a higher number of maxillary carcinomas, and a higher prevalence of pre vious second cancer.
Making decisions in cancer therapy for elderly patients is challenging. Patients suffering from operable head and neck cancer should be treated with curative intent and with regard to quality of life if a careful assessment of comorbidities is performed preoperatively. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - July 21, 2016 Category: Cancer & Oncology Source Type: research
Kruse AL, Bredell M, Gr ätz KW. Oral squamous cell carcinoma in non-smoking and non-drinking patients. Head Neck Oncol. 2010 Oct 4;2:24.
Conclusion
The group of patients with no tobacco and alcohol use tends toward a higher proportion of females, a higher proportion of patien ts over 70 years, and a higher number of oral maxillary SCC. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - July 21, 2016 Category: Cancer & Oncology Source Type: research
St Guily JL, Borget I, Vainchtock A, R émy V, Takizawa C. Head and neck cancers in France: an analysis of the hospital medical information system (PMSI) database. Head Neck Oncol. 2010 Sep 1;2:22.
Conclusion
Even without taking into account the rehabilitation costs, the hospital burden of H & amp;N cancers is considerable. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - July 21, 2016 Category: Cancer & Oncology Source Type: research
Kruse AL, Luebbers HT, Gr ätz KW. C-reactive protein levels: a prognostic marker for patients with head and neck cancer? Head Neck Oncol. 2010 Aug 2;2:21.
Conclusion
Our findings do not appear to support a correlation between preoperative CRP levels and development of recurrence or metastases. In further studies, CRP levels in precancerous lesions and in Human Papilloma Virus (HPV) positive patients with ora l squamous cell carcinoma (SCC) should be studied. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - July 21, 2016 Category: Cancer & Oncology Source Type: research
Scholz M, Parvin R, Thissen J, L öhnert C, Harders A, Blaeser K. Skull base approaches in neurosurgery. Head Neck Oncol. 2010 Jul 5;2:16.
The skull base surgery is one of the most demanding surgeries. There are different structures that can be injured easily, by operating in the skull base. It is very important for the neurosurgeon to choose the right approach in order to reach the lesion without harming the other intact structures. Due to the pioneering work of Cushing, Hirsch, Yasargil, Krause, Dandy and other dedicated neurosurgeons, it is possible to address the tumor and other lesions in the anterior, the mid-line and the posterior cranial base. With the transsphenoidal, the frontolateral, the pterional and the lateral suboccipital approach nearly every...
Source: Head and Neck Oncology - July 21, 2016 Category: Cancer & Oncology Source Type: research
HPV & head and neck cancer: a descriptive update.
The incidence of head and neck squamous cell carcinoma (HNSCC) has been gradually increasing over the last three decades. Recent data have now attributed a viral aetiology to a subset of head and neck cancers. Several studies indicate that oral human papillomavirus (HPV) infection is likely to be sexually acquired. The dominance of HPV 16 in HPV+ HNSCC is even greater than that seen in cervical carcinoma of total worldwide cases. Strong evidence suggests that HPV+ status is an important prognostic factor associated with a favourable outcome in head and neck cancers. Approximately 30 to 40% of HNSCC patients with present wi...
Source: Head and Neck Oncology - July 21, 2016 Category: Cancer & Oncology Source Type: research
Identification of potential therapeutic targets in human head & neck squamous cell carcinoma.
Conclusion
Five genes and their products may serve as a diagnostic biomarker or therapeutic target for HNSCC. While additional work is needed to elucidate the biological significance of these proteins, CD24 and CD74 expressed only in small proportion of cells indicating tumor heterogeneity and subtypes of tumor initiating cells (CD24+/CD44+) present in HNSCC. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - July 21, 2016 Category: Cancer & Oncology Source Type: research
Head & neck optical diagnostics: vision of the future of surgery.
Review paper and Proceedings of the Inaugural Meeting of the Head and Neck Optical Diagnostics Society (HNODS) on March 14th 2009 at University College London. The aim of our research must be to provide breakthrough translational research which can be applied clinically in the immediate rather than the near future. We are fortunate that this is indeed a possibility and may fundamentally change current clinical and surgical practice to improve our patients & #39; lives. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - July 21, 2016 Category: Cancer & Oncology Source Type: research
Head & Neck Oncology: purpose, scope and goals-charting the future.
For many years now there has been a growing frustration with the statistics of head and neck cancer. Despite the many advances in diagnosis and therapy, there has been little change in the prognosis for most cancers of the head and neck in the last 50 years, so what is the point of yet another journal? Well, it is not all bad news.
Declaration & nbsp; (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - July 21, 2016 Category: Cancer & Oncology Source Type: research
Controversies surrounding human papilloma virus infection, head & neck vs oral cancer, implications for prophylaxis and treatment.
Head & amp; Neck Cancer (HNC) represents the sixth most common malignancy worldwide and it is historically linked to well-known behavioural risk factors, i.e., tobacco smoking and/or the alcohol consumption. Recently, substantial evidence has been mounting that Human Papillomavirus (HPV) infection is playing an increasing important role in oral cancer. Because of the attention and clamor surrounding oral HPV infection and related cancers, as well as the use of HPV prophylactic vaccines, in this invited perspective the authors raise some questions and review some controversial issues on HPV infection and its role in HNC, wi...
Source: Head and Neck Oncology - July 21, 2016 Category: Cancer & Oncology Source Type: research
Bone reconstruction and optic functional restoration after fronto-orbital fibrous dysplasia resection.
The article has been forwarded to the production team. The processing may take few weeks. Then the proof will be forwarded to the corresponding author. The final PDF and HTML files will be uploaded when the corrections to the proof are returned by the corresponding author. (Source: Head and Neck Oncology)
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
Immunoprofile of primary gingival angiosarcoma: A case report and review of the literature.
The angiosarcoma of the oral cavity is extremely rare, with only a few such cases reported in the literature. We used a case of primary gingival angiosarcoma arising in maxilla as an opportunity to review the clinicopathological and immunohistochemical profile of this tumor in the oral cavity. A 59-years-old man had a fibrous mass involving the gingival and alveolar mucosa in the maxillary left molar region associated with extensive bone destruction. A biopsy was performed and the tumor was histopathologically diagnosed as angiosarcoma. Whereas that early diagnosis is crucial and that the definitive diagnosis of angiosarco...
Source: Head and Neck Oncology - February 13, 2015 Category: Cancer & Oncology Source Type: research
