Recombinant factor VIII Fc fusion protein for immune tolerance induction in patients with severe haemophilia A with inhibitors—A retrospective analysis
Haemophilia, EarlyView. (Source: Haemophilia)
Source: Haemophilia - February 13, 2018 Category: Hematology Source Type: research
Ligneous cervicitis and endometritis: A gynaecological presentation of congenital plasminogen deficiency
Haemophilia, EarlyView. (Source: Haemophilia)
Source: Haemophilia - February 13, 2018 Category: Hematology Source Type: research
Clinical trials and registries in haemophilia: Opponents or collaborators? Comparison of PUP data derived from different data sources
Haemophilia, EarlyView. (Source: Haemophilia)
Source: Haemophilia - February 13, 2018 Category: Hematology Source Type: research
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Haemophilia, Ahead of Print. (Source: Haemophilia)
Source: Haemophilia - February 13, 2018 Category: Hematology Source Type: research
Clinical trials and registries in haemophilia: Opponents or collaborators? Comparison of PUP data derived from different data sources
ConclusionsPreviously performed CTs in PUPs were divergent, which prevented a direct comparison of outcomes. However, this study demonstrated that data from CTs and carefully designed registries may complement each other in the establishing of sufficient safety information for single products to improve clinical insights and support regulatory decisions. (Source: Haemophilia)
Source: Haemophilia - February 13, 2018 Category: Hematology Authors: C. Keipert, C. J. Jonker, H. M. Berg, A. Hilger Tags: ORIGINAL ARTICLE Source Type: research
Ligneous cervicitis and endometritis: A gynaecological presentation of congenital plasminogen deficiency
ConclusionsThis is a chronic condition requiring a multidisciplinary approach. There is currently no definitive treatment for the condition, current trials with plasminogen concentrate replacement therapy may provide a promising option for these patients in the future. (Source: Haemophilia)
Source: Haemophilia - February 13, 2018 Category: Hematology Authors: M. Baithun, T. Freeman ‐Wang, P. Chowdary, R. A. Kadir Tags: REVIEW ARTICLE Source Type: research
Recombinant factor VIII Fc fusion protein for immune tolerance induction in patients with severe haemophilia A with inhibitors—A retrospective analysis
ConclusionsRecombinant factor VIII Fc fusion protein demonstrated rapid time to tolerization in high‐risk first‐time ITI patients. For rescue ITI, rFVIIIFc showed therapeutic benefit in some patients who previously failed ITI with other products. These findings highlight the need to further evaluate the use of rFVIIIFc for ITI. (Source: Haemophilia)
Source: Haemophilia - February 13, 2018 Category: Hematology Authors: M. Carcao, A. Shapiro, J. M. Staber, N. Hwang, C. Druzgal, K. Lieuw, M. Belletrutti, C. D. Thornburg, S. P. Ahuja, J. Morales ‐Arias, J. Dumont, G. Miyasato, E. Tsao, N. Jain, S. W. Pipe Tags: ORIGINAL ARTICLE Source Type: research
Pocket handheld ultrasound for evaluation of the bleeding haemophilic joint: A novel and reliable way to recognize joint effusions
Haemophilia, EarlyView. (Source: Haemophilia)
Source: Haemophilia - February 12, 2018 Category: Hematology Source Type: research
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Haemophilia, Ahead of Print. (Source: Haemophilia)
Source: Haemophilia - February 12, 2018 Category: Hematology Source Type: research
Pocket handheld ultrasound for evaluation of the bleeding haemophilic joint: A novel and reliable way to recognize joint effusions
(Source: Haemophilia)
Source: Haemophilia - February 12, 2018 Category: Hematology Authors: J. Y. Zhou, K. C. Rappazzo, L. Volland, R. F. W. Barnes, M. Brackman, B. Steiner, R. Kruse ‐Jarres, D. V. Quon, C. Bailey, E. Y. Chang, A. Drygalski Tags: LETTER TO THE EDITOR Source Type: research
Advantage of recombinant von Willebrand factor for peri ‐operative management in paediatric acquired von Willebrand syndrome
Haemophilia, EarlyView. (Source: Haemophilia)
Source: Haemophilia - February 8, 2018 Category: Hematology Source Type: research
The importance of ABO blood group in pharmacokinetic studies in haemophilia A
Haemophilia, EarlyView. (Source: Haemophilia)
Source: Haemophilia - February 8, 2018 Category: Hematology Source Type: research
