Extracellular Hsp70 modulates the inflammatory response of cigarette smoke extract in NCI ‐H292 cells
In this study, we explored inflammatory parameters (cytokine concentrations, Toll‐like receptor (TLR) 2 and 4 and Hsp70 expression, mitogen‐activated protein kinases (MAPKs) and nuclear factor κB (NF‐κB) activation, and cytotoxicity) after exposure of bronchial‐epithelial NCI‐H292 cells to cigarette smoke extract (CSE) alone (2.5 and 15%) and in combinations with recombinant human (rh) Hsp70 (0.3, 1 and 3 μg ml−1). We applied specific MAPKs, NF ‐κB and Hsp70 inhibitors to elucidate rhHsp70 inflammation‐associated responses. CSE alone and combinations of 15% CSE with rhHsp70 stimulated IL‐1α, IL‐6...
Source: Experimental Physiology - November 10, 2018 Category: Physiology Authors: Andrea Hulina ‐Tomašković,
Marija Grdić Rajković,
Anita Somborac‐Bačura,
Andrea Čeri,
Sanja Dabelić,
Lada Rumora Tags: RESEARCH PAPER Source Type: research
Down ‐regulation of lncRNA XIST ameliorates podocytes apoptosis in membranous nephropathy via miR‐217/TLR4 pathway
ConclusionDown ‐regulation of XIST ameliorates podocytes apoptosis via the miR‐217/TLR4 pathway, which may improve membranous nephropathy.This article is protected by copyright. All rights reserved (Source: Experimental Physiology)
Source: Experimental Physiology - November 10, 2018 Category: Physiology Authors: Ling ‐wei Jin,
Min Pan,
Han‐yang Ye,
Yu Zheng,
Yan Chen,
Wen‐wen Huang,
Xiao‐yan Xu,
Shu‐bei Zheng Tags: RESEARCH PAPER Source Type: research
Extracellular Hsp70 modulates the inflammatory response of cigarette smoke extract in NCI ‐H292 cells
In this study, we explored inflammatory parameters (cytokine concentrations, Toll‐like receptor (TLR) 2 and 4 and Hsp70 expression, mitogen‐activated protein kinases (MAPKs) and nuclear factor κB (NF‐κB) activation, and cytotoxicity) after exposure of bronchial‐epithelial NCI‐H292 cells to cigarette smoke extract (CSE) alone (2.5 and 15%) and in combinations with recombinant human (rh) Hsp70 (0.3, 1 and 3 μg ml−1). We applied specific MAPKs, NF ‐κB and Hsp70 inhibitors to elucidate rhHsp70 inflammation‐associated responses. CSE alone and combinations of 15% CSE with rhHsp70 stimulated IL‐1α, IL‐6...
Source: Experimental Physiology - November 10, 2018 Category: Physiology Authors: Andrea Hulina ‐Tomašković,
Marija Grdić Rajković,
Anita Somborac‐Bačura,
Andrea Čeri,
Sanja Dabelić,
Lada Rumora Tags: RESEARCH PAPER Source Type: research
Down ‐regulation of lncRNA XIST ameliorates podocytes apoptosis in membranous nephropathy via miR‐217/TLR4 pathway
ConclusionDown ‐regulation of XIST ameliorates podocytes apoptosis via the miR‐217/TLR4 pathway, which may improve membranous nephropathy.This article is protected by copyright. All rights reserved (Source: Experimental Physiology)
Source: Experimental Physiology - November 10, 2018 Category: Physiology Authors: Ling ‐wei Jin,
Min Pan,
Han‐yang Ye,
Yu Zheng,
Yan Chen,
Wen‐wen Huang,
Xiao‐yan Xu,
Shu‐bei Zheng Tags: RESEARCH PAPER Source Type: research
Low ‐level transcutaneous vagus nerve stimulation attenuates cardiac remodeling in a rat model of heart failure with preserved ejection fraction
This article is protected by copyright. All rights reserved (Source: Experimental Physiology)
Source: Experimental Physiology - November 6, 2018 Category: Physiology Authors: Liping Zhou,
Adrian Filiberti,
Mary Beth Humphrey,
Christian D. Fleming,
Benjamin J. Scherlag,
Sunny S. Po,
Stavros Stavrakis Tags: RESEARCH PAPER Source Type: research
Genetic variant in the β2‐adrenergic receptor (Arg16Gly) influences fat‐free mass, muscle strength and motor unit behaviour in young men
Experimental Physiology, EarlyView. (Source: Experimental Physiology)
Source: Experimental Physiology - November 2, 2018 Category: Physiology Authors: Nathaniel D. M. Jenkins,
Ryan J. Colquhoun,
Patrick M. Tomko,
Trey Gradnigo,
Mitchel A. Magrini,
Tyler W. D. Muddle,
Sydnie Fleming,
Matthew Ferrell,
Ahmed El ‐Sohemy Source Type: research
Characterizing the plasma metabolome during 14 days of live ‐high, train‐low simulated altitude: A metabolomic approach
Experimental Physiology, EarlyView. (Source: Experimental Physiology)
Source: Experimental Physiology - November 2, 2018 Category: Physiology Authors: Nathan G. Lawler,
Chris R. Abbiss,
Joel P. A. Gummer,
David I. Broadhurst,
Andrew D. Govus,
Timothy J. Fairchild,
Kevin G. Thompson,
Laura A. Garvican ‐Lewis,
Christopher J. Gore,
Garth L. Maker,
Robert D. Trengove,
Jeremiah J. Peiffer Source Type: research
Genetic variant in the β2‐adrenergic receptor (Arg16Gly) influences fat‐free mass, muscle strength and motor unit behaviour in young men
Experimental Physiology, EarlyView. (Source: Experimental Physiology)
Source: Experimental Physiology - November 2, 2018 Category: Physiology Authors: Nathaniel D. M. Jenkins,
Ryan J. Colquhoun,
Patrick M. Tomko,
Trey Gradnigo,
Mitchel A. Magrini,
Tyler W. D. Muddle,
Sydnie Fleming,
Matthew Ferrell,
Ahmed El ‐Sohemy Source Type: research
Characterizing the plasma metabolome during 14 days of live ‐high, train‐low simulated altitude: A metabolomic approach
Experimental Physiology, EarlyView. (Source: Experimental Physiology)
Source: Experimental Physiology - November 2, 2018 Category: Physiology Authors: Nathan G. Lawler,
Chris R. Abbiss,
Joel P. A. Gummer,
David I. Broadhurst,
Andrew D. Govus,
Timothy J. Fairchild,
Kevin G. Thompson,
Laura A. Garvican ‐Lewis,
Christopher J. Gore,
Garth L. Maker,
Robert D. Trengove,
Jeremiah J. Peiffer Source Type: research
Corrigendum
Experimental Physiology,Volume 103, Issue 11, Page 1571-1571, 1 November 2018. (Source: Experimental Physiology)
Source: Experimental Physiology - November 1, 2018 Category: Physiology Source Type: research
Editorial Board
Experimental Physiology,Volume 103, Issue 11, Page 1572-1574, 1 November 2018. (Source: Experimental Physiology)
Source: Experimental Physiology - November 1, 2018 Category: Physiology Source Type: research
Corrigendum
Experimental Physiology,Volume 103, Issue 11, Page 1571-1571, 1 November 2018. (Source: Experimental Physiology)
Source: Experimental Physiology - November 1, 2018 Category: Physiology Source Type: research
Editorial Board
Experimental Physiology,Volume 103, Issue 11, Page 1572-1574, 1 November 2018. (Source: Experimental Physiology)
Source: Experimental Physiology - November 1, 2018 Category: Physiology Source Type: research
