Case Report: Persistent Acromegaly – Effective Therapy with Lanreotide and Weekly Pegvisomant Injections
Conclusions Excessive growth hormone secretion persisting after pituitary surgery and irradiation can be controlled in a convenient way for the patient with acromegaly by combining monthly lanreotide and weekly pegvisomant injections, if monotherapy with a somatostatin analog fails. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: Experimental and Clinical Endocrinology and Diabetes Reports)
Source: Experimental and Clinical Endocrinology and Diabetes Reports - June 11, 2018 Category: Endocrinology Authors: Sch ürmeyer, Thomas H. Galling, Britta Tags: Case Report Source Type: research

Worsening Cardiac Function in a Patient with Friedreich ’s Ataxia Secondary to Profound Hypothyroidism
We present a case of declining cardiac function in a patient with Friedreich's Ataxia, however, her worsening cardiac function was not related to her chronic disease. Her declining cardiac function was associated with hypothyroidism that was initially overlooked. The purpose of this article is to remind physicians of the role that thyroid hormone has in cardiac function and overall health. Autoimmune hypothyroidism is a common condition, and physicians should consider screening thyroid function in any patient with poor or worsening cardiac function. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJo...
Source: Experimental and Clinical Endocrinology and Diabetes Reports - March 20, 2018 Category: Endocrinology Authors: Thrasher, Bradly J. Whitham, Jennifer Law, Jennifer Tags: Case Report Source Type: research

Lymphocytic Adrenal Medullitis: Case Report of A Patient with Pheochromocytoma-Like Hypertensive Paroxysms
We describe the finding of LAM in a 66-year old female presenting with hyperaldosteronism and a 17 mm lesion in the right adrenal gland. The patient displayed secondary hypertension as well as intermittently occurring exaggerated hypertensive episodes with systolic peaks above 220 mm Hg. Preoperative catecholamine screening was negative, diminishing the possibility of a pheochromocytoma. Unilateral adrenalectomy was performed, and histology revealed an aldosterone producing adrenocortical adenoma. No signs of adrenomedullary hyperplasia or pheochromocytoma were found; however, prominent B- and T-lymphocytic infiltrates...
Source: Experimental and Clinical Endocrinology and Diabetes Reports - January 22, 2018 Category: Endocrinology Authors: Calissendorff, Jan Christofer Juhlin, Carl Tags: Case Report Source Type: research

Alstrom Syndrome with Novel ALMS1 Mutations: A Case Report
Conclusions 2 novel heterozygous non-sense mutations were identified in the Chinese Child with Alstrom syndrome, expanding the ALMS1 gene mutations causing Alstrom syndrome. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text (Source: Experimental and Clinical Endocrinology and Diabetes Reports)
Source: Experimental and Clinical Endocrinology and Diabetes Reports - August 23, 2017 Category: Endocrinology Authors: Liu, Lanrong Li, Hong Shi, Lixin Tags: Case Report Source Type: research

Prevalence of Eating Disorders in Individuals with Type 2 Diabetes: A Cohort Comparison of Patients and Controls
Exp Clin Endocrinol Diabetes Rep DOI: 10.1055/s-0043-103347 To determine the prevalence of eating disorders (ED) in a cohort of patients with type 2 diabetes (T2DM), to identify the more predominant forms of ED, and to clarify if ED is associated with impaired metabolic control. A cohort of 517 patients with T2DM aged≥40 years and a control cohort of 304 patients without diabetes, age and gender matched, were enrolled from 3 primary care centres. All subjects completed the Questionnaire of Eating and Weight Patterns-Revised (QEWP-R), followed by a structured interview (EDE 17th version). The overall prevalence of ED in p...
Source: Experimental and Clinical Endocrinology and Diabetes Reports - April 13, 2017 Category: Endocrinology Authors: Garc ía-Mayor, Ricardo V. Garc ía-Soidán, Francisco Javier Salgado Barreira, Angel Tags: Short Communication Source Type: research

Frequency of Genital Infections According to Body Mass Index in Dapagliflozin-treated Patients with Type 2 Diabetes Mellitus
Exp Clin Endocrinol Diabetes Rep DOI: 10.1055/s-0043-101823 Genital infections are associated with sodium glucose co-transporter 2 inhibitors such as dapagliflozin. Since patients with Type 2 diabetes are at increased risk of genital infections, and obesity is a risk factor for infections, obese patients with Type 2 diabetes could be more susceptible to genital infections when treated with sodium glucose co-transporter 2 inhibitors. This pooled dataset assessed the frequency of genital infections according to baseline body mass index in patients treated with dapagliflozin 10 mg. Data were pooled from 13 studies of up to ...
Source: Experimental and Clinical Endocrinology and Diabetes Reports - March 15, 2017 Category: Endocrinology Authors: Rudofsky, Gottfried Haenni, Tanja Xu, John Johnsson, Eva Tags: Short Communication Source Type: research

Statin Intolerance in a Patient with Gilberts Syndrome and Hypercholesterolemia
We report on a 60 year old male with Hypercholesterolemia (HC) who was referred for management of his HC since he had statin intolerance manifesting as myalgias and was shown to have Gilbert’s Syndrome. Case Report: Investigation of this patient revealed he had Familial Combined Hyperlipidemia with a LDL-cholesterol of 189 mg/dl. He was also diagnosed with Gilbert’s Syndrome since he had elevated unconjugated bilirubin with no evidence of liver disease or hemolysis. The combination of Niacin, Cholestyramine and ezetimibe resulted in a successful decrease in his LDL-cholesterol to 114 mg/dl. Discussion: We believe t...
Source: Experimental and Clinical Endocrinology and Diabetes Reports - September 12, 2016 Category: Endocrinology Authors: Jialal, I. Siegel, D. Tags: Case Report Source Type: research

What makes Lymphadenopathy in Patients with Autoimmune Thyroiditis Suspicious for Malignancy?
Exp Clin Endocrinol Diabetes RepDOI: 10.1055/s-0035-1569376Lymphadenopathy in Robbins level II-IV and VI is common in autoimmune thyroiditis but the diagnostic strategy of a distinct lymphadenopathy exceeding the known features in autoimmune thyroiditis patients is unknown. The aim of this study was to determine how the extent of cervical lymphadenopathy in autoimmune thyroiditis affects the diagnostic management.The study comprises one index-patient with autoimmune thyroiditis and distinct suspicious lymphadenopathy in all cervical levels as well as retroclavicular. In addition 10 patients with autoimmune thyroiditis and ...
Source: Experimental and Clinical Endocrinology and Diabetes Reports - April 5, 2016 Category: Endocrinology Authors: Bouter, C.Meller, B.Meller, J.Sahlmann, C. O. Tags: Case Report Source Type: research

Macroprolactin: the Role of Serial Measurement Throughout Pregnancy
Conclusion: In this case report, serial measurement of macroprolactin with estimation of monomeric prolactin enhanced clinical management throughout pregnancy, saving unnecessary further investigations and avoiding unnecessary distress for the patient.[...]© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: Experimental and Clinical Endocrinology and Diabetes Reports)
Source: Experimental and Clinical Endocrinology and Diabetes Reports - February 5, 2016 Category: Endocrinology Authors: Livingston, M.Nair, S.Radford, D.Kane, J.Heald, A. H. Tags: Case Report Source Type: research

Creatine Kinase Elevation during Antithyroid Treatment of a Patient with Graves’ Disease: A Case Report and Review of Literature
We present a young male patient with Graves’ disease who had abnormal increase of CK level during treatment with methimazole (MMI). He experienced myalgia and elevated CK level 1 month after initiation of MMI. In the beginning of the myalgia, his free T4 level decreased to normal range. After dose reduction of MMI, CK level decreased and his symptoms were resolved. Although the mechanisms for this effect are not yet clear, it is thought that rapid decrease in thyroid hormone by antithyroid treatment in susceptible patients with graves’ disease can be the cause of CK elevation. Measuring CK level in Graves disease patie...
Source: Experimental and Clinical Endocrinology and Diabetes Reports - February 5, 2016 Category: Endocrinology Authors: Uçan, B.Yüksek, C.Kizilgul, M.Erten, R.Konuk, G.Mercan, Z.Atik, F.Demir, F.Cakal, E. Tags: Case Report Source Type: research

Creatine Kinase Elevation during Antithyroid Treatment of a Patient with Graves ’ Disease: A Case Report and Review of Literature
We present a young male patient with Graves’ disease who had abnormal increase of CK level during treatment with methimazole (MMI). He experienced myalgia and elevated CK level 1 month after initiation of MMI. In the beginning of the myalgia, his free T4 level decreased to normal range. After dose reduction of MMI, CK level decreased and his symptoms were resolved. Although the mechanisms for this effect are not yet clear, it is thought that rapid decrease in thyroid hormone by antithyroid treatment in susceptible patients with graves’ disease can be the cause of CK elevation. Measuring CK level in Graves disease patie...
Source: Experimental and Clinical Endocrinology and Diabetes Reports - February 4, 2016 Category: Endocrinology Authors: U çan, B. Y üksek, C. Kizilgul, M. Erten, R. Konuk, G. Mercan, Z. Atik, F. Demir, F. Cakal, E. Tags: Case Report Source Type: research

Sunlight Deficiency: a Reversible Cause of Low Serum Phosphate?
Exp Clin Endocrinol Diabetes Rep 2015; 02: e11-e13DOI: 10.1055/s-0035-1554690Vitamin D deficiency is associated with low circulating levels of calcium and phosphate.A 56-year-old asymptomatic gentleman was referred with laboratory findings of undetectable serum phosphate (< 0.16 mmol/L) and a history of calcified renal calculi. 25-hydroxyvitamin D (25-OHD) was low at 19.0 nmol/L (concentrations of <30 nmol/L are indicative of vitamin D deficiency). Serum adjusted calcium was normal at 2.38 mmol/L (reference range (RR): 2.0–2.6), as was parathyroid hormone. 24-h urine calcium excretion was elevated at 10.8...
Source: Experimental and Clinical Endocrinology and Diabetes Reports - July 28, 2015 Category: Endocrinology Authors: Heald, A. H.Radford, D.Nair, S.Livingston, M. Tags: Case Report Source Type: research

Case Report: Isolated Pauci-immune Vasculitis of the Pituitary Gland Revealed by Stereotactic Biopsy
Conclusions: Vasculitis of the pituitary gland is a rare condition. Less than 50 cases have been described to date in patients with granulomatosis with polyangiitis (GPA, or Wegener’s granulomatosis) and few case reports exist on pituitary involvement in other systemic vasculitis like Behcet’s disease and Cogan’s syndrome 1 2 3 4 5 6 7 8 9. Pituitary involvement in GPA predominantly affects the posterior pituitary gland resulting in central diabetes insipidus (DI) but global or partial anterior pituitary dysfunction and compression of the optic chiasm has also been described (10). Relapse and permanent residual pitui...
Source: Experimental and Clinical Endocrinology and Diabetes Reports - April 21, 2015 Category: Endocrinology Authors: Roelz, R.Erny, D.Shah, M. J.Egger, K.Thiel, J.Seufert, J.Laubner, K.Reinacher, P. Tags: Case Report Source Type: research

Intrasellar Rathke’s Cleft Cyst and Acromegaly: an Unusual Coincidence
We describe a case of a GH-secreting pituitary adenoma complicated by the presence of an asymptomatic intrasellar Rathke’s cleft cyst and review the already reported cases.[...]© Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals:Table of contents  |  Abstract  |  open access Full text (Source: Experimental and Clinical Endocrinology and Diabetes Reports)
Source: Experimental and Clinical Endocrinology and Diabetes Reports - April 21, 2015 Category: Endocrinology Authors: Efstathiadou, Z. A.Poulasouchidou, M. K.Zouli, C.Anastasiou, A.Kita, M. D. Tags: Case Report Source Type: research

Autoimmune Thyroid Disease and Refractory Chronic Urticaria: Thyroidectomy as a Treatment for Long Standing Remission. A Case Report
We present the case of a 36-year-old woman who developed a chronic autoimmune urticaria that did not respond to conservative treatment. During the initial study, she was diagnosed with a euthyroid autoimmune disease, that evolved into a subclinical hyperthyroidism 2 months later. Even though thyroid function was restored with anti-thyroid drugs, urticaria persisted, and finally it was decided to perform a thyroidectomy. After surgery, the patient stayed asymptomatic from the dermatological point of view, with no relapses more than 2 years later. Therefore, thyroidectomy is proposed as a new therapeutical option in patients...
Source: Experimental and Clinical Endocrinology and Diabetes Reports - October 14, 2014 Category: Endocrinology Authors: Francés, C.Nicolau, J.García, M.Nadal, C.Gómez, L. A.Masmiquel, L. Tags: Case Report Source Type: research