Hepatic Lipid Accumulation and Nrf2 Expression following Perinatal and Peripubertal Exposure to Bisphenol A in a Mouse Model of Nonalcoholic Liver Disease
Conclusion:
Exposure to a xenobiotic during early development induced persistent fat accumulation via hypomethylation of lipogenic genes. Moreover, increased Nrf2 recruitment to the Srebp-1c promoter in livers of BPA-exposed mice was observed. Overall, the underlying mechanisms described a broader impact beyond BPA exposure and can be applied to understand other models of NAFLD. https://doi.org/10.1289/EHP664
Received: 15 June 2016
Revised: 28 January 2017
Accepted: 31 January 2017
Published: 04 August 2017
Address correspondence to A.L. Slitt, Biomedical and Pharmaceutical Sciences, University of Rhode Island, 7 Gre...
Source: EHP Research - August 5, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Endocrine Disruption in Human Fetal Testis Explants by Individual and Combined Exposures to Selected Pharmaceuticals, Pesticides, and Environmental Pollutants
Conclusions:
Our results with the FEGA provide the foundations of a predictive human mixture risk assessment approach for anti-androgenic exposures in fetal life. https://doi.org/10.1289/EHP1014
Received: 25 August 2016
Revised: 02 March 2017
Accepted: 20 March 2017
Published: 04 August 2017
Address correspondence to B. Jégou, EHESP, IRSET-UMR Inserm 1085, 9 Ave. du professeur Léon Bernard, F-35000 Rennes, France. Telephone: 33.2.23.23.61.25. Email: bernard.jegou@ehesp.fr
Supplemental Material is available online (https://doi.org/10.1289/EHP1014).
The authors declare they have no actual or potential competing finan...
Source: EHP Research - August 4, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Developmental PBDE Exposure and IQ/ADHD in Childhood: A Systematic Review and Meta-analysis
Conclusion:
We concluded there was sufficient evidence supporting an association between developmental PBDE exposure and reduced IQ. Preventing developmental exposure to PBDEs could help prevent loss of human intelligence. https://doi.org/10.1289/EHP1632
Received: 16 January 2017
Revised: 28 April 2017
Accepted: 28 April 2017
Published: 03 August 2017
Address correspondence to J. Lam, Program on Reproductive Health and the Environment, University of California, San Francisco, Mail Stop 0132, 550 16th St., 7th floor, San Francisco, CA 94143 USA. Telephone: (415) 476-3219. Email: Juleen.Lam@ucsf.edu
Supplemental Materi...
Source: EHP Research - August 3, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Review Source Type: research
The Case for Universal Screening of Private Well Water Quality in the U.S. and Testing Requirements to Achieve It: Evidence from Arsenic
Conclusions:
Universal screening, achieved through local testing requirements complemented by greater community engagement targeting biologically and socioeconomically vulnerable groups, would reduce population arsenic exposure greater than any promotional efforts to date. Universal screening of private well water will identify the dangers hidden in America’s drinking water supply and redirect attention to ensure safe water among affected households. https://doi.org/10.1289/EHP629
Received: 08 June 2016
Revised: 13 December 2016
Accepted: 29 December 2016
Published: 03 August 2017
Address correspondence to Y. Zheng...
Source: EHP Research - August 3, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Commentary Source Type: research
Associations between Greenness, Impervious Surface Area, and Nighttime Lights on Biomarkers of Vascular Aging in Chennai, India
Conclusion:
Greenness, ISA, and NTL were associated with increased SBP, DBP, and cPP, and with reduced FMD, suggesting a possible additional EVA pathway for the relationship between urbanization and increased CVD prevalence in urban India. https://doi.org/10.1289/EHP541
Received: 20 May 2016
Revised: 03 January 2017
Accepted: 23 January 2017
Published: 02 August 2017
Address correspondence to K.J. Lane, Yale School of Forestry and Environmental Studies, 195 Prospect Street, New Haven, CT 06511 USA. Telephone: (781) 696-4537; Email: kevin.lane@yale.edu
Supplemental Material is available online (https://doi.org/10.1289...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Estimated Effects of Future Atmospheric CO2 Concentrations on Protein Intake and the Risk of Protein Deficiency by Country and Region
Conclusions:
Anthropogenic CO2 emissions threaten the adequacy of protein intake worldwide. Elevated atmospheric CO2 may widen the disparity in protein intake within countries, with plant-based diets being the most vulnerable. https://doi.org/10.1289/EHP41
Received: 27 February 2016
Revised: 12 September 2016
Accepted: 19 September 2016
Published: 02 August 2017
Address correspondence to D. Medek, North Shore Hospital, Shakespeare Ave., Takapuna, Auckland, New Zealand 0622. Telephone: 649 486 8900. Email: danielle.medek@gmail.com
Supplemental Material is available online (https://doi.org/10.1289/EHP41).
The authors d...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
The Association of Arsenic Metabolism with Cancer, Cardiovascular Disease, and Diabetes: A Systematic Review of the Epidemiological Evidence
Conclusions:
Population level of iAs% and DMA%, but not MMA%, were associated with arsenic exposure levels. Overall, study findings suggest that higher MMA% was associated with an increased risk of cancer and cardiovascular disease, while lower MMA% was associated with an increased risk of diabetes and metabolic syndrome. Additional population-based studies and experimental studies are needed to further evaluate and understand the role of arsenic exposure in arsenic metabolism and the role of arsenic metabolism in disease development. https://doi.org/10.1289/EHP577
Received: 01 June 2016
Revised: 26 February 2017
Acce...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Opportunities and Challenges for Personal Heat Exposure Research
Conclusions:
Personal heat exposure research provides more valid and precise insights into how often people encounter heat conditions and when, where, to whom, and why these encounters occur. Published literature on personal heat exposure is limited to date, but existing studies point to opportunities to inform public health practice regarding extreme heat, particularly where fine-scale precision is needed to reduce health consequences of heat exposure. https://doi.org/10.1289/EHP556
Received: 24 May 2016
Revised: 17 January 2017
Accepted: 20 January 2017
Published: 01 August 2017
Address correspondence to D.M. Hondu...
Source: EHP Research - August 2, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Commentary Source Type: research
Nature Contact and Human Health: A Research Agenda
Conclusions:
Nature contact may offer a range of human health benefits. Although much evidence is already available, much remains unknown. A robust research effort, guided by a focus on key unanswered questions, has the potential to yield high-impact, consequential public health insights. https://doi.org/10.1289/EHP1663
Received: 26 January 2017
Revised: 12 May 2017
Accepted: 25 May 2017
Published: 31 July 2017
Address correspondence to H. Frumkin, Dept. of Environmental and Occupational Health Sciences, University of Washington School of Public Health, Box 354695, Seattle, WA 98195-4695 USA; Telephone: 206-897-1723;...
Source: EHP Research - July 31, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Commentary Source Type: research
The Imperial County Community Air Monitoring Network: A Model for Community-based Environmental Monitoring for Public Health Action
Author Affiliations open
1California Department of Public Health, Richmond, California, USA
2Comite Civico Del Valle, Brawley, California, USA
3Department of Environmental & Occupational Health Sciences, University of Washington, Seattle, Washington, USA
4California Environmental Health Tracking Program, Public Health Institute, Oakland, California, USA
5School of Public Health, University of California, Los Angeles, California, USA
6Department of Environmental and Occupational Health Sciences, George Washington University, Washington, D.C., USA
PDF Version (723 KB)
Abstract
About This Article
Summary...
Source: EHP Research - July 31, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Brief Communication Source Type: research
Assessing Exposure to Household Air Pollution: A Systematic Review and Pooled Analysis of Carbon Monoxide as a Surrogate Measure of Particulate Matter
Conclusions:
Our results suggest that exposure to CO is not a consistently valid surrogate measure of exposure to PM2.5. Studies measuring CO exposure as a surrogate measure of PM exposure should conduct local validation studies for different stove/fuel types and seasons. https://doi.org/10.1289/EHP767
Received: 06 July 2016
Revised: 19 December 2016
Accepted: 20 December 2016
Published: 28 July 2017
Address correspondence to J. Baumgartner, Institute for Health and Social Policy and Department of Epidemiology, Biostatistics and Occupational Health, 1130 des Pins Ave. Ouest, Montréal, Québec H3A 1A3 Canada. Telepho...
Source: EHP Research - July 29, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Review Source Type: research
Exposure to Ambient Particulate Matter during Specific Gestational Periods Produces Adverse Obstetric Consequences in Mice
Conclusions:
Adverse PM2.5-induced outcomes such as PTB and LBW are dependent upon the periods of maternal exposure. The results of these experimental studies could contribute significantly to air pollution policy decisions in the future. https://doi.org/10.1289/EHP1029
Received: 26 August 2016
Revised: 12 December 2016
Accepted: 23 January 2017
Published: 27 July 2017
Address correspondence to J. Zelikoff, Department of Environmental Medicine, New York University School of Medicine, 57 Old Forge Rd., Tuxedo, NY 10987 USA. Telephone: (845) 731-3528. Email: Judith.Zelikoff@nyumc.org
The authors declare they have no ac...
Source: EHP Research - July 28, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Ambient Coarse Particulate Matter and the Right Ventricle: The Multi-Ethnic Study of Atherosclerosis
Conclusions:
Alterations to RV structure may represent a mechanism by which long-term PM10–2.5 exposure increases risks for adverse respiratory and cardiovascular outcomes, especially among certain susceptible populations. https://doi.org/10.1289/EHP658
Received: 14 June 2016
Revised: 24 February 2017
Accepted: 16 March 2017
Published: 27 July 2017
Address correspondence to S. D. Adar, University of Michigan School of Public Health, 1415 Washington Heights, SPH II-5539, Ann Arbor, MI 48109 USA. Telephone: (734) 615-9207; Email: sadar@umich.edu
Supplemental Material is available online (https://doi.org/10.1289/EHP65...
Source: EHP Research - July 27, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Serum Vaccine Antibody Concentrations in Adolescents Exposed to Perfluorinated Compounds
Conclusions:
These results are in accord with previous findings of PFAS immunotoxicity at current exposure levels. https://doi.org/10.1289/EHP275
Received: 09 February 2016
Revised: 06 June 2016
Accepted: 12 July 2016
Published: 26 July 2017
Address correspondence to P. Grandjean, HSPH-EOME, 401 Park Dr., 3E L3-045, Boston, MA 02215 USA. Telephone: 617-384-8907. Email: pgrandjean@health.sdu.dk
The authors declare they have no actual or potential competing financial interests.
Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and S...
Source: EHP Research - July 26, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
Serum Vaccine Antibody Concentrations in Adolescents Exposed to Perfluorinated Compounds
Conclusions:
These results are in accord with previous findings of PFAS immunotoxicity at current exposure levels. https://doi.org/10.1289/EHP275
Received: 09 February 2016
Revised: 06 June 2016
Accepted: 12 July 2016
Published: 26 July 2017
Address correspondence to P. Grandjean, HSPH-EOME, 401 Park Dr., 3E L3-045, Boston, MA 02215 USA. Telephone: 617-384-8907. Email: pgrandjean@health.sdu.dk
The authors declare they have no actual or potential competing financial interests.
Note to readers with disabilities: EHP strives to ensure that all journal content is accessible to all readers. However, some figures and S...
Source: EHP Research - July 26, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research
