Ambient Temperature and Early Delivery of Singleton Pregnancies
Author Affiliations open 1Epidemiology Branch, Division of Intramural Population Health Research, NICHD, Rockville, MD, USA; 2Biostatistics and Bioinformatics Branch, Division of Intramural Population Health Research, NICHD, Rockville, MD, USA; 3The Emmes Corporation, Rockville, MD, USA PDF Version (422 KB) Abstract About This Article Supplemental Material Background: Extreme temperature is associated with adverse birth outcomes but it is unclear whether it increases early delivery risk. Objectives: Determine the association between ambient temperature and early delivery. Methods: Medical records from 223,...
Source: EHP Research - August 31, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

In Vitro Effects of Lead on Gene Expression in Neural Stem Cells and Associations between Upregulated Genes and Cognitive Scores in Children
Conclusion: Our findings revealed that Pb induces an NRF2-dependent transcriptional response in neural stem cells and identified SPP1 upregulation as a potential novel mechanism linking Pb exposure with neural stem cell function and neurodevelopment in children. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you ...
Source: EHP Research - August 26, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Cardiovascular Benefits of Wearing Particulate-Filtering Respirators: A Randomized Crossover Trial
Conclusions: Short-term wearing of particulate-filtering respirators may obtain cardiovascular benefits in improving autonomic nervous function and reducing BP. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Shi J, Lin ...
Source: EHP Research - August 26, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Associations between Unconventional Natural Gas Development and Nasal and Sinus, Migraine Headache, and Fatigue Symptoms in Pennsylvania
Conclusions: This study provides evidence that UNGD is associated with nasal and sinus, migraine headache, and fatigue symptoms in a general population representative sample. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citatio...
Source: EHP Research - August 25, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Climate Change and Future Pollen Allergy in Europe
Conclusions: Our quantitative estimates indicate that ragweed pollen allergy will become a common health problem across Europe, expanding into areas where it is currently uncommon. Control of ragweed spread may be an important adaptation strategy in response to climate change. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in ...
Source: EHP Research - August 24, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Polychlorinated Biphenyl and Organochlorine Pesticide Concentrations in Maternal Mid-Pregnancy Serum Samples: Association with Autism Spectrum Disorder and Intellectual Disability
Conclusions: Our results suggest higher levels of some organochlorine compounds during pregnancy are associated with ASD and ID. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Lyall K, Croen LA, Sjödin A, Yoshida CK, ...
Source: EHP Research - August 23, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Estimating Inorganic Arsenic Exposure from U.S. Rice and Total Water Intakes
Conclusions: An average consumer drinking 1.5 L of water daily that contains between 2 and 3 ng iAs/mL is exposed to approximately the same amount of iAs as a mean Tribal, Asian, and Pacific consumer is exposed to from rice. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document...
Source: EHP Research - August 19, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Historical Trends in PM2.5-Related Premature Mortality during 1990-2010 across the Northern Hemisphere
Conclusions: Over the past two decades, correlations between population and PM2.5 have become weaker in Europe and North America due to air pollution controls but stronger in East Asia due to deteriorating air quality. Mitigation of primary PM appears to be the most efficient way for increasing health benefits, i.e., providing the largest mortality reduction per unit emissions. However, reductions in emissions of NH3 are needed to maximize the effectiveness of NOx emission controls. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication ar...
Source: EHP Research - August 19, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Soy Formula and Epigenetic Modifications: Analysis of Vaginal Epithelial Cells from Infant Girls in the IFED Study
Author Affiliations open 1Epigenetics & Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA; 2Epidemiology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA; 3Reproductive & Developmental Biology Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA; 4Biostatistics & Computational Biology Branch, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, North Carolina, USA; 5Division ...
Source: EHP Research - August 19, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Reassessing the Link between Airborne Arsenic Exposure among Anaconda Copper Smelter Workers and Multiple Causes of Death Using the Parametric g-Formula
Conclusions: Our analyses suggest that the excess deaths from causes other than respiratory cancers comprise the majority of the excess deaths caused by inhaled arsenic exposure. Healthy worker survivor bias may have masked such associations in prior analyses. These results emphasize the need for consideration of all exposure routes for upcoming risk assessment by the United States Environmental Protection Agency. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the ...
Source: EHP Research - August 19, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

A Study of Reverse Causation: Examining the Associations of Perfluorooctanoic Acid Serum Levels with Two Outcomes
Author Affiliations open aDepartment of Environmental Health, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA. rdhingra@emory.edu; mklein@emory.edu; awinqui@emory.edu; nsteenl@emory.edu; bDepartment of Epidemiology, Rollins School of Public Health, Emory University, 1518 Clifton Road, Atlanta, GA 30322, USA. ldarrow@emory.edu PDF Version (366 KB) Abstract About This Article Supplemental Material Background: Impaired kidney function and earlier menopause were associated with perfluorooctanoic acid (PFOA) serum levels in prior cross-sectional studies. Reverse causati...
Source: EHP Research - August 16, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

The Association between Ambient Fine Particulate Air Pollution and Lung Cancer Incidence: Results from the AHSMOG-2 Study
Conclusion: Increased risk estimates of LC were observed for each 10-µg/m3 increment in ambient PM2.5 concentration. The estimate was higher among those with longer residence at enrollment address and those who spent more than 1 hr/day outdoors. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be a...
Source: EHP Research - August 12, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Disinfection By-Product Exposures and the Risk of Specific Cardiac Birth Defects
Conclusions: To our knowledge, this is the first birth defect study to develop multi-DBP adjusted regression models and is the second study to evaluate HAAs or brominated DBP exposures. Our findings, therefore, inform exposure specificity for the consistent associations previously reported between THM4 and CVDs including VSDs. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon ...
Source: EHP Research - August 12, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Association of Ambient Air Pollution with Depressive and Anxiety Symptoms in Older Adults: Results from the NSHAP Study
Conclusion: PM2.5 was associated with depressive and anxiety symptoms, with associations the strongest in individuals with lower SES or had certain health-related characteristics. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Ci...
Source: EHP Research - August 12, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Low-Dose Mixture Hypothesis of Carcinogenesis Workshop: Scientific Underpinnings and Research Recommendations
Conclusions: The theoretical merits of the Low-dose Carcinogenesis Hypothesis are well founded with clear biological relevance, and therefore, the premise warrants further investigation. Expert recommendations include the need for better insights into the ways in which non-carcinogenic constituents might combine to uniquely affect the process of cellular transformation (in vitro) and environmental carcinogenesis (in vivo), including investigations of the role of key defense mechanisms in maintaining transformed cells in a dormant state. The scientific community will need to acknowledge limitations of animal-based ...
Source: EHP Research - August 12, 2016 Category: Environmental Health Authors: Web Admin Tags: Review Source Type: research

Occupational Asbestos Exposure and Incidence of Colon and Rectal Cancers in French Men: The Asbestos-Related Diseases Cohort (ARDCo-Nut)
Conclusions: Our findings provide support for an association between occupational exposure to asbestos and colon cancer incidence in men. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Paris C, Thaon I, Hérin F, Cli...
Source: EHP Research - August 12, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Passive Sampling for Indoor and Outdoor Exposures to Chlorpyrifos, Azinphos-Methyl, and Oxygen Analogs in a Rural Agricultural Community
Author Affiliations open 1Department of Occupational and Environmental Health, University of Iowa College of Public Health, Iowa City, Iowa, United States; 2Department of Environmental and Occupational Health Sciences, University of Washington School of Public Health, Seattle, Washington, United States PDF Version (307 KB) Abstract About This Article Supplemental Material Background: Recent studies have highlighted the increased potency of oxygen analogs of organophosphorus pesticides. These pesticides and oxygen analogs have previously been identified in the atmosphere following spray applications in Cal...
Source: EHP Research - August 12, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

The Prevalence and Use of Walking Loops in Neighborhood Parks: A National Study
Conclusions: Walking loops may be a promising means of increasing population level physical activity. Further studies are needed to confirm a causal relationship. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Cohen DA,...
Source: EHP Research - August 12, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Biomarker Levels of Toxic Metals among Asian Populations in the U.S.: NHANES 2011 –2012
Author Affiliations open 1The University of Texas Health Science Center at Houston School of Public Health, Houston, Texas, U.S.A; 2CH2M HILL, Inc., Houston Texas, U.S.A PDF Version (246 KB) Abstract About This Article Supplemental Material Introduction: The Centers for Disease Control and Prevention (CDC) recently found Asians have considerably higher biomarker levels of cadmium, lead, mercury, and arsenic than whites, blacks, Mexican Americans, and other Hispanics in the U.S. Objective: To further evaluate the higher metal biomarker levels among Asians. Methods: Biomarker data (blood cadmium, blood le...
Source: EHP Research - August 12, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Genes Interacting with Occupational Exposures to Low Molecular Weight Agents and Irritants on Adult-Onset Asthma in Three European Studies
Author Affiliations open 1INSERM, U1168, VIMA: Aging and chronic diseases. Epidemiological and public health approaches, F-94807, Villejuif, France; 2Spanish National Cancer Research Centre (CNIO), Genetic & Molecular Epidemiology Group, Human Cancer Genetics Program, 28029 Madrid, Spain; 3Inserm UMR 1181 « Biostatistics, Biomathematics, Pharmacoepidemiology and Infectious Diseases » (B2PHI), F-94807 Villejuif, France; 4Institut Pasteur, UMR 1181, B2PHI, F-75015 Paris, France; 5Univ Versailles St Quentin-en-Yvelines, UMR 1181, B2PHI, F-78180, Montigny le Bretonneux, France; 6ISGlobal, Centre for Resear...
Source: EHP Research - August 9, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Serum Vaccine Antibody Concentrations in Adolescents Exposed to Perfluorinated Compounds
Conclusions: These results are in accordance with previous findings of PFAS immunotoxicity at current exposure levels. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Grandjean P, Heilmann C, Weihe P, Nielsen F, Mogensen UB...
Source: EHP Research - August 9, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Risk of Congenital Heart Defects after Ambient Heat Exposure Early in Pregnancy
Conclusions: Extreme heat exposure during the first trimester may be associated with noncritical heart defects, especially of the atrial septum. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Auger N, Fraser WD, Sauve R...
Source: EHP Research - August 5, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Perinatal Exposure to Traffic-Related Air Pollution and Autism Spectrum Disorders
Author Affiliations open 1Department of Medical Epidemiology and Biostatistics, Karolinska Institutet; 2Department of Public Health Sciences, Karolinska Institutet; 3Center for Epidemiology and Community Medicine, Stockholm County Council; 4Astrid Lindgren Children’s Hospital, Karolinska University Hospital; 5Institute of Environmental Medicine, Karolinska Institutet; 6Center for Occupational and Environmental Medicine, Stockholm County Council, Stockholm, Sweden PDF Version (1 MB) Abstract About This Article Supplemental Material Background: Studies from the United States indicate that exposure to air pol...
Source: EHP Research - August 5, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Residential Exposure to Natural Background Radiation and Risk of Childhood Acute Leukemia in France, 1990 – 2009
Conclusions: Our findings do not support the hypothesis that residential exposure to NBR increases the risk of AL, despite the large size of the study, fine scale exposure estimates and wide range of exposures over France. However, our results at the time of diagnosis do not rule out a slight association with gamma radiation at the time of birth, which would be more in line with the recent findings in the UK and Switzerland. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assig...
Source: EHP Research - August 2, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

School Siting Near Industrial Chemical Facilities: Findings from the U.S. Chemical Safety Board ’s Investigation of the West Fertilizer Explosion
Conclusions: In light of the current lack of federal authority for oversight of land use near educational institutions, state and local governments should take a proactive role in promulgating state regulations that prohibit the siting of public receptors, such as buildings occupied by children, near facilities that store hazardous chemicals. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted ...
Source: EHP Research - August 2, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Evaluating the Impact of the U.S. National Toxicology Program: A Case Study on Hexavalent Chromium
Conclusions: This study identified a broad and objective approach for assessing NTP’s effectiveness, including methodological needs for more thorough and efficient impact assessments in the future. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the...
Source: EHP Research - August 2, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

EHP Highlights of the Past Year
Discussions about these issues at the 2016 Council of Science Editors meeting (which Shaun and I attended) stressed the need for clear guidelines and sustainable infrastructure to support such efforts. With these and other challenges ahead, I am looking forward to another successful and productive year for EHP and to receiving your best papers! (Source: EHP Research)
Source: EHP Research - August 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Editorial August 2016 Source Type: research

A Multimedia E-Book —A Story of Health: Filling a Gap in Environmental Health Literacy for Health Professionals
Author Affiliations open 1Western States Pediatric Environmental Health Specialty Unit, University of California San Francisco, San Francisco, California, USA; 2California Environmental Protection Agency, Oakland, California, USA; 3Collaborative on Health and the Environment, Bolinas, California, USA; 4Science and Environmental Health Network, Ames, Iowa, USA; 5Environmental Medicine Branch, Division of Toxicology and Human Health Sciences, Agency for Toxic Substances and Disease Registry, Atlanta, Georgia, USA PDF Version (3 MB) Summary About This Article Narrative approaches and storytelling are emerging a...
Source: EHP Research - August 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Brief Communication August 2016 Source Type: research

It Came From Beneath: Detecting and Mitigating Vapor Intrusion
Although indoor air quality has been a topic of intense public health inquiry for many years, it’s only been relatively recent that vapor intrusion has been recognized as a source of indoor air contaminants. Today researchers are searching for better ways to measure and control volatile chemicals that can enter buildings from the soil and groundwater beneath them.© JG Photography/Alamy Stock Photo Vapor intrusion is often associated with contaminated groundwater. The widespread use of volatile chemicals has resulted in innumerable groundwater plumes across the United States, some documented, ...
Source: EHP Research - August 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News August 2016 Source Type: research

The Exposome: Embracing the Complexity for Discovery in Environmental Health
Conclusions A decade after the original publication of the exposome concept, followed by years of fruitful discussions on the challenges of implementing it in research, the time is ripe to use the concept to guide study design, to understand the complex nature of exposure, and to embrace that complexity when exploring the relationship between exposure and human health and its underlying mechanisms. It is vital to identify case studies where we can refine and improve epidemiological findings via incorporation of the exposome concept, including expanded exposure measurements, increased understanding of exposure variations ac...
Source: EHP Research - August 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Brief Communication August 2016 Source Type: research

The Uncertain Relationship between Air Pollution and Risk of Preterm Birth: Does Spatial Variation Drive Disparate Findings?
Nate Seltenrich covers science and the environment from Petaluma, CA. His work has appeared in High Country News, Sierra, Yale Environment 360, Earth Island Journal, and other regional and national publications. About This Article open Citation: Seltenrich N. 2016. The uncertain relationship between air pollution and risk of preterm birth: does spatial variation drive disparate findings? Environ Health Perspect 124:A147; http://dx.doi.org/10.1289/ehp.124-A147 Published: 1 August 2016 PDF Version (255 KB) Related EHP Article Ambient Fine Particulate Matter, Nitrogen Dioxide, and Preterm Birth in New York City Sarah Jo...
Source: EHP Research - August 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection August 2016 Source Type: research

Arsenic and the Placental Epigenome: Unlocking the Secrets of Prenatal Exposure
Lindsey Konkel is a New Jersey–based journalist who reports on science, health, and the environment. About This Article open Citation: Konkel L. 2016. Arsenic and the placental epigenome: unlocking the secrets of prenatal exposure. Environ Health Perspect 124:A148; http://dx.doi.org/10.1289/ehp.124-A148 Published: 1 August 2016 PDF Version (399 KB) Related EHP Article Epigenome-Wide Assessment of DNA Methylation in the Placenta and Arsenic Exposure in the New Hampshire Birth Cohort Study (USA) Benjamin B. Green, Margaret R. Karagas, Tracy Punshon, Brian P. Jackson, David J. Robbins, E. Andres Houseman, and C...
Source: EHP Research - August 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection August 2016 Source Type: research

An Informatics Approach to Reading the Label: Identifying Common Chemical Mixtures in Personal Care Products
Carol Potera, based in Montana, also writes for Microbe, Genetic Engineering News, and the American Journal of Nursing. About This Article open Citation: Potera C. 2016. An informatics approach to reading the label: identifying common chemical mixtures in personal care products. Environ Health Perspect 124:A149; http://dx.doi.org/10.1289/ehp.124-A149 Published: 1 August 2016 PDF Version (285 KB) Related EHP Article An Informatics Approach to Evaluating Combined Chemical Exposures from Consumer Products: A Case Study of Asthma-Associated Chemicals and Potential Endocrine Disruptors Henry A. Gabb and Catherine Blake F...
Source: EHP Research - August 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection August 2016 Source Type: research

Organoarsenic Drugs over Time: The Pharmacokinetics of Roxarsone in Chicken Meat
Lindsey Konkel is a New Jersey–based journalist who reports on science, health, and the environment. About This Article open Citation: Konkel L. 2016. Organoarsenic drugs over time: the pharmacokinetics of roxarsone in chicken meat. Environ Health Perspect 124:A150; http://dx.doi.org/10.1289/ehp.124-A150 Published: 1 August 2016 PDF Version (284 KB) Related EHP Article Arsenic Species in Chicken Breast: Temporal Variations of Metabolites, Elimination Kinetics, and Residual Concentrations Qingqing Liu, Hanyong Peng, Xiufen Lu, Martin J. Zuidhof, Xing-Fang Li, and X. Chris Le Although “market basket”...
Source: EHP Research - August 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection August 2016 Source Type: research

Mortality due to Vegetation-Fire Originated PM2.5 Exposure in Europe – Assessment for the Years 2005 and 2008
Conclusions: Our assessment suggests that air pollution due to PM2.5 released from vegetation fires is a notable risk factor for public health in Europe. Moreover, the risk can be expected to increase in the future as the climate change proceeds. This should be taken into consideration when evaluating the overall health and socio-economic impacts of the fires. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced w...
Source: EHP Research - July 29, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Long-Term Exposure to Traffic-Related Air Pollution and Risk of Incident Atrial Fibrillation: A Cohort Study
Conclusion: We found long-term residential traffic-related air pollution to be associated with higher risk of atrial fibrillation. Accordingly, the present findings lend further support to the demand for abatement of air pollution. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to...
Source: EHP Research - July 29, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

IL-33 Drives Augmented Responses to Ozone in Obese Mice
Conclusions: Our data indicate that IL-33 contributes to augmented responses to ozone in obese mice. Obesity and ozone also interacted to promote type 2 cytokine production in γδ T cells and ILC2 in the lungs, which may contribute to the observed effects of IL-33. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI n...
Source: EHP Research - July 29, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Ambient Air Pollutant Exposures and Hospitalization for Kawasaki Disease in Taiwan: A Case-Crossover Study (2000-2010)
Conclusions: Our results provide new evidence that exposure to O3 may increase the risk of KD in children. However, further investigation is needed to confirm the association and identify a potential biological mechanism. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access th...
Source: EHP Research - July 26, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Relative Contributions of Agricultural Drift, Para-Occupational, and Residential Use Exposure Pathways to House Dust Pesticide Concentrations: Meta-Regression of Published Data
Conclusion: Our quantification of the relative contributions of pesticide exposure pathways in agricultural populations could improve exposure assessments in epidemiologic studies. The meta-regression models can be updated when additional data become available. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the cit...
Source: EHP Research - July 26, 2016 Category: Environmental Health Authors: Web Admin Tags: Review Source Type: research

Estimated Costs of Sporadic Gastrointestinal Illness Associated with Surface Water Recreation: A Combined Analysis of Data from NEEAR and CHEERS Studies
Conclusions: Our estimates suggest gastrointestinal illness attributed to surface water recreation at urban waterways, lakes, and coastal marine beaches is responsible for costs that should be accounted for when considering the monetary impact of efforts to improve water quality. The COI provides more information than the frequency of illness, as it takes into account disease incidence, healthcare utilization, and lost productivity. Use of monetized disease severity information should be included in future studies of water quality and health. This EHP Advance Publication article has...
Source: EHP Research - July 26, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Prenatal Residential Proximity to Agricultural Pesticide Use and IQ in 7-Year-Old Children
Conclusions: This study identified potential relationships between maternal residential proximity to agricultural use of neurotoxic pesticides and poorer neurodevelopment in children. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publi...
Source: EHP Research - July 25, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

An Integrated Experimental Design for the Assessment of Multiple Toxicological End Points in Rat Bioassays
Conclusion: This integrated study design is efficient in that the same generational cohort of rats used for evaluating long-term outcomes can be monitored in satellite parallel experiments to measure biomarkers and other parameters related to system-specific responses including metabolic alterations and endocrine disturbances. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted v...
Source: EHP Research - July 22, 2016 Category: Environmental Health Authors: Web Admin Tags: Commentary Source Type: research

In Utero Exposure to Benzo[a]Pyrene Increases Mutation Burden in the Soma and Sperm of Adult Mice
Conclusion: We show that in utero exposure to environmental mutagens contributes to somatic and germline mosaicism, permanently impacting both the genetic health of the F1 and the population gene pool. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each ...
Source: EHP Research - July 22, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Manganese in Drinking Water and Cognitive Abilities and Behavior at 10 Years of Age: A Prospective Cohort Study
Author Affiliations open 1Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; 2International Centre for Diarrhoeal Disease Research, Bangladesh (icddr,b), Dhaka, Bangladesh; 3Center of Neurodevelopmental Disorders (KIND), Pediatric Neuropsychiatry Unit, Department of Women’s and Children’s Health, Karolinska Institutet, Stockholm, Sweden; 4Center for Psychiatry Research, Stockholm County Council, Stockholm, Sweden #Authors contributed equally †Corresponding author: Maria Kippler, Institute of Environmental Medicine, Karolinska Institutet, Box 210, SE-171 77, Stockholm...
Source: EHP Research - July 22, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Epigenome-Wide Meta-Analysis of Methylation in Children Related to Prenatal NO2 Air Pollution Exposure
Author Affiliations open 1Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden; 2University of Groningen, University Medical Center Groningen, Department of Pulmonology, Groningen Research Institute for Asthma and COPD (GRIAC), Groningen, the Netherlands; 3University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, the Netherlands; 4University of Southern California, Department of Preventive Medicine, Los Angeles, CA, USA; 5Department of Epidemiology of Allergic and Respiratory Diseases, Institut National de la Santé et de la Recherche Médical...
Source: EHP Research - July 22, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Polybrominated Diphenyl Ethers in Human Milk and Serum from the US EPA MAMA Study: Modeled Predictions of Infant Exposure and Considerations for Risk Assessment
Conclusions: Concentrations and partitioning ratios of PBDEs in milk and serum from women in the U.S. EPA MAMA Study are presented for the first time; modeled predictions of milk PBDE concentrations using serum concentrations appear to be a valid method for estimating PBDE exposure in U.S. infants. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is avail...
Source: EHP Research - July 12, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Occupational Exposure to Pesticides and the Incidence of Lung Cancer in the Agricultural Health Study
Conclusions: These analyses provide additional evidence for an association between pendimethalin, dieldrin, and parathion use and lung cancer risk. We found an association between chlorimuron-ethyl, a herbicide introduced in 1986, and lung cancer that has not been previously reported. Continued follow-up is warranted. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as...
Source: EHP Research - July 6, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research

Prenatal PBDE and PCB Exposures and Reading, Cognition, and Externalizing Behavior in Children
Conclusion: Prenatal PBDE concentration was inversely associated with reading skills and FSIQ, positively associated with Externalizing Problems at age 8 years. No significant associations were found in prenatal PCB concentration. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to ...
Source: EHP Research - July 6, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Short-Term Exposure to Urban Air Pollution and Influences on Placental Vascularization Indexes
Conclusions: NO2, an estimator of primary air pollutants, was significantly associated with diminished VI and VFI in the first trimester of pregnancy. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Hettfle...
Source: EHP Research - July 6, 2016 Category: Environmental Health Authors: Web Admin Tags: Children's Health Source Type: research

Early Postnatal Manganese Exposure Causes Lasting Impairment of Selective and Focused Attention and Arousal Regulation in Adult Rats
Conclusions: This study is the first to show that developmental Mn exposure can cause lasting impairments in focused and selective attention and arousal regulation, and to identify the specific nature of the impairments. Given the importance of attention and arousal regulation in cognitive functioning, these findings substantiate concerns about the adverse effects of developmental Mn exposure in humans. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to...
Source: EHP Research - July 6, 2016 Category: Environmental Health Authors: Web Admin Tags: Research Article Source Type: research