What’s NORMal for Fracking? Estimating Total Radioactivity of Produced Fluids
This study lays the foundation for a more detailed investigation of the health impacts of radioactive waste that may be generated from fracking.” Burch was not involved in the current study. Because fracking activities and wastewater disposal often take place in close proximity to where people live and work, there’s a potential for human exposure, according to Burch. “The technology is vastly outpacing what we know about the health effects,” he says. A few cases of radioactive contamination outside of wastewater treatment facilities have been documented. In one notable example, researchers studied w...
Source: EHP Research - July 1, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Energy Ionizing Radiation July 2015 Mining Source Type: research

POPs and Gut Microbiota: Dietary Exposure Alters Ratio of Bacterial Species
Carol Potera, based in Montana, also writes for Microbe, Genetic Engineering News, and the American Journal of Nursing. About This Article open Citation: Potera C. 2015. POPs and gut microbiota: dietary exposure alters ratio of bacterial species. Environ Health Perspect 123:A187; http://dx.doi.org/10.1289/ehp.123-A187 News Topics: Dioxins and Furans, Microbiology, Microbiome, Obesity, Persistent Organic Pollutants (POPs) Published: 1 July 2015 PDF Version (403 KB) Related EHP Article Persistent Organic Pollutants Modify Gut Microbiota–Host Metabolic Homeostasis in Mice Through Aryl Hydrocarbon Receptor Ac...
Source: EHP Research - July 1, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Dioxins and Furans July 2015 Microbiology Microbiome Obesity Persistent Organic Pollutants (POPs) Source Type: research

The Emergence of Environmental Health Literacy—From Its Roots to Its Future Potential
Conclusions: We posit that EHL can potentially benefit the conduct and outcomes of community-engaged and health disparities EHS research and ensure that the translation of research findings lead to greater understanding of specific risks, the reduction of exposures, and the improvement of health outcomes for individuals and communities. We provide four recommendations to advance work in EHL. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced ...
Source: EHP Research - June 30, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Commentary Source Type: research

Exposure to Road Traffic Noise and Behavioral Problems in 7-Year-Old Children: A Cohort Study
Conclusions: Residential road traffic noise in early childhood may be associated with behavioral problems, particularly hyperactivity/inattention symptoms. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Hjortebjerg D, Andersen AM...
Source: EHP Research - June 30, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Prenatal Exposure to NO2 and Ultrasound Measures of Fetal Growth in the Spanish INMA Cohort
Conclusions: Maternal exposure to NO2 in early pregnancy was associated with reduced fetal growth based on ultrasound measures of growth during pregnancy and measures of size at birth. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation:&nb...
Source: EHP Research - June 26, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Cord Blood Methylmercury and Fetal Growth Outcomes in Baltimore Newborns: Potential Confounding and Effect Modification by Omega-3 Fatty Acids, Selenium, and Sex
Conclusion: We observed an association of increased MeHg with decreased ponderal index. There is evidence for interaction between MeHg and n-3 HUFAs; infants with higher MeHg and n-3 HUFAs had lower birth length and head circumference. These results should be verified with additional studies. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in ...
Source: EHP Research - June 26, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Mechanisms Underlying Latent Disease Risk Associated with Early-Life Arsenic Exposure: Current Research Trends and Scientific Gaps
Conclusions: Evidence is mounting that relates early-life iAs exposure and cancer development later in life. Future research should include animal studies that address mechanistic hypotheses and studies of human populations that integrate early-life exposure, molecular alterations, and latent disease outcomes. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the D...
Source: EHP Research - June 26, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Commentary Source Type: research

Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood
Conclusions: Our findings provide evidence for early childhood lead exposure resulting in sex-dependent and gene-specific DNA methylation differences in the DMRs of PEG3, IGF2/H19 and PLAGL1/HYMAI in adulthood. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publica...
Source: EHP Research - June 26, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Prenatal Phthalate, Perfluoroalkyl Acid, and Organochlorine Exposures and Term Birth Weight in Three Birth Cohorts: Multi-Pollutant Models Based on Elastic Net Regression
Conclusions: This study suggests that several of the environmental contaminants, belonging to three chemical classes, may be independently associated with impaired fetal growth. These results warrant follow-up in other cohorts. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each sta...
Source: EHP Research - June 26, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Synergistic and Antagonistic Mutation Responses of Human MCL-5 Cells to Mixtures of Benzo[a]pyrene and 2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]pyridine: Dose-Related Variation in the Joint Effects of Common Dietary Carcinogens
Conclusions: Mixtures of these genotoxic chemicals produced mutation responses that differed from expectations for additive effects of the individual chemicals. The increase in MF for some combinations of chemicals at low concentrations that were not genotoxic for the individual chemicals, and the non-monotonic dose response, may be important for understanding the mutagenic potential of food and the etiology of diet-associated cancers. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to...
Source: EHP Research - June 19, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

First-Trimester Urine Concentrations of Phthalate Metabolites and Phenols and Placenta miRNA Expression in a Cohort of U.S. Women
The objective of this study was to determine if prenatal exposure to multiple EDCs is associated with changes in miRNA expression of human placenta, and if miRNA alterations are associated with birth outcomes. Methods: Our study was restricted to a total of 179 women co-enrolled in the Harvard Epigenetic Birth Cohort and the Predictors of Preeclampsia Study. We analyzed associations between first-trimester urine concentrations of 8 phenols and 11 phthalate metabolites and expression of 29 candidate miRNAs in placenta by qRT-PCR. Results: For three miRNAs, miR-142-3p, miR15a-5p, and miR-185, we detected associations between...
Source: EHP Research - June 19, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Associations of Pregnancy Outcomes and PM2.5 in a National Canadian Study
Author Affiliations open 1Population Studies Division, Health Canada, Vancouver, British Columbia, Canada; 2Population Studies Division, Health Canada, Ottawa, Ontario, Canada; 3Geographic Information Health and Exposure Science Laboratory (GIS HEAL), School of Public Health, University of California, Berkeley, Berkeley, California, USA; 4Department of Environmental Health Sciences, Fielding School of Public Health, University of California, Los Angeles, Los Angeles, California, USA; 5Department of Sociology, University of New Brunswick, Fredericton, New Brunswick, Canada; 6Special Surveys Divisio...
Source: EHP Research - June 19, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Impact of Exposure Uncertainty on the Association between Perfluorooctanoate and Preeclampsia in the C8 Health Project Population
Conclusions: We found that correlated exposure uncertainty can substantially change estimated PFOA serum concentrations but results in only minor impacts on the epidemiological association between PFOA and preeclampsia. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of th...
Source: EHP Research - June 19, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Use of the Adaptive LASSO Method to Identify PM2.5 Components Associated with Blood Pressure in Elderly Men: The Veterans Affairs Normative Aging Study
Conclusions: Our study suggested exposure to ambient Ni was associated with increased blood pressure independent of PM2.5 mass in our study population of elderly men. Further research is needed to confirm our findings, assess generalizability to other populations, and identify potential mechanisms for Ni effects. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through th...
Source: EHP Research - June 19, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Evidence from Toxicology: The Most Essential Science for Prevention
Conclusion: The adoption of evidence based principles and methods will enhance the validity, transparency, efficiency and acceptance of toxicological evidence, with benefits in terms of reducing delays and costs for all stakeholders (researchers, consumers, regulators, industry). This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation,...
Source: EHP Research - June 19, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Commentary Source Type: research

Occupational Lead Exposure and Associations with Selected Cancers: The Shanghai Men’s and Women’s Health Study Cohorts
Conclusions: Our findings, though limited by small numbers of cases, suggest that lead is associated with risk of several cancers in women and men. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Liao LM, Friesen MC, Xiang Y-B, Ca...
Source: EHP Research - June 19, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Effects of Laser Printer–Emitted Engineered Nanoparticles on Cytotoxicity, Chemokine Expression, Reactive Oxygen Species, DNA Methylation, and DNA Damage: A Comprehensive in Vitro Analysis in Human Small Airway Epithelial Cells, Macrophages, and Lymphoblasts
Conclusions: The in vitro findings here suggest that laser printer-emitted engineered nanoparticles may be deleterious to lung cells, and provide preliminary evidence of epigenetic modifications that might translate to pulmonary disorders. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document...
Source: EHP Research - June 16, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Use of a Cumulative Exposure Index to Estimate the Impact of Tap-Water Lead Concentration on Blood Lead Levels in 1- to 5-Year-Old Children (Montreal, Canada)
Author Affiliations open 1Centre de recherche du CHU de Québec, Axe Santé des populations et pratiques optimales en Santé, Québec, Québec, Canada; 2Faculté de médecine, Département de médecine sociale et préventive, Université Laval, Québec, Québec, Canada; 3École de Santé Publique de l’Université de Montréal (ESPUM), Département de santé environnementale et de santé au travail, Montréal, Québec, Canada; 4Institut national de santé publiq...
Source: EHP Research - June 16, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Suicide and Ambient Temperature in East Asian Countries: A Time-Stratified Case-Crossover Analysis
Conclusions: We estimated consistent positive associations between suicide and higher ambient temperature in three East Asian countries, regardless of country, gender, and age. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation: Kim Y...
Source: EHP Research - June 12, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Air Pollution Exposure during Pregnancy and Childhood Autistic Traits in Four European Population-Based Cohort Studies: The ESCAPE Project
Author Affiliations open 1Center for Research in Environmental Epidemiology, Barcelona, Spain; 2Pompeu Fabra University, Barcelona, Spain; 3Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain; 4Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Centre–Sophia Children’s Hospital, Rotterdam, the Netherlands; 5The Generation R Study, Erasmus University Medical Centre, Rotterdam, the Netherlands; 6Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockhol...
Source: EHP Research - June 12, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Prenatal Exposure to Phthalates and Childhood Body Size in an Urban Cohort
Author Affiliations open 1Division of Pediatric Endocrinology, Diabetes and Metabolism, Department of Pediatrics, New York-Presbyterian Hospital, Columbia University, New York, New York, USA; 2Columbia Center for Children’s Environmental Health, Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York, USA; 3Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, USA; 4Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevent...
Source: EHP Research - June 12, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Chronic Exposure to Arsenic and Markers of Cardiometabolic Risk—A Cross-Sectional Study in Chihuahua, Mexico
Author Affiliations open 1Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; 2Carolina Population Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; 3Lineberger Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA; 4Programa de Maestría en Ciencias en Biotecnología, Facultad de Ciencias Químicas, Universidad Autónoma de Chihuahua, Chihuahua, México; 5Colegio de Médicos Cirujanos y Home&oac...
Source: EHP Research - June 12, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Particulate Air Pollution Exposure and Expression of Viral and Human MicroRNAs in Blood: The Beijing Truck Driver Air Pollution Study
Author Affiliations open 1Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA; 2Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA; 3Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; 4Bioinformatics Infrastructure Facility, University of Rajasthan, Jaipur and Barupal Research Foundation, Jaisalmer, India; 5Department of Pediatrics, University of Illinois, Chicago, Illinois, USA; 6Institute for Public Health and M...
Source: EHP Research - June 12, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Association of Perfluoroalkyl Substances, Bone Mineral Density, and Osteoporosis in the U.S. Population in NHANES 2009–2010
Author Affiliations open 1Center for Global Health, Department of Community Health, Boonshoft School of Medicine, Wright State University, Dayton, Ohio, USA; 2Division of Epidemiology and Biostatistics, Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA; 3Lifespan Health Research Center, Department of Community Health, Wright State University, Dayton, Ohio, USA; 4The Pediatric Lipid Clinic, Dayton’s Children Hospital, Dayton, Ohio, USA; 5Department of Pharmacology and Toxicology, Brody School of Medicine, East Carolina University, Gre...
Source: EHP Research - June 9, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Confusion about Cadmium Risks: The Unrecognized Limitations of an Extrapolated Paradigm
Conclusions: Cd risk assessment paradigm needs to be rethought by considering that low-level U-Cd is strongly influenced by renal physiology, recent exposure and factors linked to studied outcomes. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process....
Source: EHP Research - June 9, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Commentary Source Type: research

Organochlorine Compounds and Ultrasound Measurements of Fetal Growth in the INMA Cohort (Spain)
Conclusions: To our knowledge, this is the first study to report an association between prenatal exposure to some PCBs and HCB and fetal growth: AC during the first two trimesters of pregnancy, and BPD and FL later in pregnancy. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each st...
Source: EHP Research - June 9, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Perfluorooctane Sulfonate Concentrations in Amniotic Fluid, Biomarkers of Fetal Leydig Cell Function, and Cryptorchidism and Hypospadias in Danish Boys (1980-1996)
Author Affiliations open 1Department of Occupational Medicine, Aarhus University Hospital, Aarhus, Denmark; 2Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; 3Division of Occupational and Environmental Medicine, Lund University, Lund, Sweden; 4Department of Occupational and Environmental Medicine, Copenhagen University Hospital, Bispebjerg, Copenhagen, Denmark; 5Danish Center for Neonatal Screening, Department of Clinical Biochemistry and Immunology, Statens Serum Institute, Copenhagen, Denmark; 6School of Biosciences, University of Nottingham, Nottingham, Uni...
Source: EHP Research - June 5, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Elemental Constituents of Particulate Matter and Newborn’s Size in Eight European Cohorts
Author Affiliations open 1Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain; 2CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain; 3Universitat Pompeu Fabra, Barcelona, Spain; 4INSERM (National Institute of Health and Medical Research), U823, Team of Environmental Epidemiology Applied to Reproduction and Respiratory Health, IAB, Grenoble, France; 5Institute for Risk Assessment Sciences, Utrecht University, Utrecht, the Netherlands; 6Department of Environmental and Occupational Health Sciences, University of Washington, Seattle, Washington, USA...
Source: EHP Research - June 5, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Geographic Variation in the Association between Ambient Fine Particulate Matter (PM2.5) and Term Low Birth Weight in the United States
Conclusions: Our study provided additional evidence on the associations between PM2.5 exposure during pregnancy and term LBW from a national perspective. The magnitude and direction of the estimated associations between PM2.5 exposure and term LBW varied by geographic locations in the US. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the ...
Source: EHP Research - June 5, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Paired Serum and Urine Concentrations of Biomarkers of Diethyl Phthalate, Methyl Paraben, and Triclosan in Rats
Conclusions: Our study highlights the importance of careful consideration of the oral dose used in animal experiments and provides useful information in selecting doses for future studies. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publication process. Citation...
Source: EHP Research - June 5, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

High Ambient Temperatures and Risk of Motor Vehicle Crashes in Catalonia, Spain (2000–2011): A Time-Series Analysis
Conclusions: Motor vehicle crashes involving driver performance were increased in association with heat waves and increasing temperature. These findings are relevant to design preventive plans in a context of global warming. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage ...
Source: EHP Research - June 5, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Low-Concentration PM2.5 and Mortality: Estimating Acute and Chronic Effects in a Population-Based Study
Conclusions: Using a mutually adjusted model, we estimated significant acute and chronic effects of PM2.5 exposures below current EPA standards. These findings suggest that improving air quality below current standards may benefit public health. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this do...
Source: EHP Research - June 3, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Prenatal Exposure to Perfluoroalkyl Acids and Serum Testosterone Concentrations at 15 Years of Age in Female ALSPAC Study Participants
Conclusions: Our findings were based on a small study sample and should be interpreted with caution. However, they suggest that prenatal exposure to some PFAAs may alter testosterone concentrations in females. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this document at each stage of the publicat...
Source: EHP Research - June 2, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Screening for Chemical Contributions to Breast Cancer Risk: A Case Study for Chemical Safety Evaluation
Conclusions: This approach could inform the development of toxicity testing that targets mechanisms relevant to breast cancer, providing a basis for identifying safer chemicals. The study identified important endpoints not currently evaluated by federal testing programs, including altered mammary gland development, Her2 activation, progesterone receptor activity, prolactin effects, and aspects of ER-beta activity. This approach could be extended to identify the biological processes and screening methods relevant for other common diseases. This EHP Advance Publication article has been peer-reviewed, revised, and accepted ...
Source: EHP Research - June 2, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Review Source Type: research

Atmospheric Interactions and Cardiac Arrhythmias
Department of Cardiology, University Hospital Center Split, Split, Croatia About This Article open Citation: Čulić V. 2015. Atmospheric interactions and cardiac arrhythmias. Environ Health Perspect 123:A144; http://dx.doi.org/10.1289/ehp.1409636 E-mail: viktor.culic@st.t-com.hr The author declares he has no actual or potential competing financial interests. Final Publication: 1 June 2015 PDF Version (85 KB) Although plausible pathophysiological mechanisms link air pollution to arrhythmogenesis, among them altered autonomic tone, repolarization abnormalities, oxidative stress, myocardial ischemia, and increas...
Source: EHP Research - June 1, 2015 Category: Environmental Health Authors: Web Admin Tags: Correspondence June 2015 Source Type: research

Atmospheric Interactions and Cardiac Arrhythmias: Langrish et al. Respond
1University/BHF Centre for Cardiovascular Science, University of Edinburgh, United Kingdom; 2Department of Public Health and Clinical Medicine, Division of Medicine/Respiratory Medicine, Umeå University, Umeå, Sweden About This Article open Citation: Langrish JP, Bosson JA, Sandström T, Blomberg A, Newby DE, Mills NL. 2015. Atmospheric interactions and cardiac arrhythmias: Langrish et al. respond. Environ Health Perspect 123:A144–A145; http://dx.doi.org/10.1289/ehp.1409636R E-mail: d.e.newby@ed.ac.uk The authors declare they have no actual or potential competing financial interests. Final Publ...
Source: EHP Research - June 1, 2015 Category: Environmental Health Authors: Web Admin Tags: Correspondence June 2015 Source Type: research

Concerns about Direct Potable Reuse
Russian River Watershed Protection Committee About This Article open Citation: Adelman B. 2015. Concerns about direct potable reuse. Environ Health Perspect 123:A146; http://dx.doi.org/10.1289/ehp.1509914 E-mail: rrwpc-1@comcast.net The author is chair of and receives partial payment for her work on behalf of Russian River Watershed Protection Committee. Final Publication: 1 June 2015 PDF Version (89 KB) According to Dahl (2014), water shortages in parts of the United States are so dire that attitudes toward wastewater reuse, including direct injection into drinking water, are becoming more favorable. He noted...
Source: EHP Research - June 1, 2015 Category: Environmental Health Authors: Web Admin Tags: Correspondence June 2015 Source Type: research

Erratum: New Developments at EHP
About This Article open Final Publication: 1 June 2015 PDF Version (47 KB) Schroeder JC, Booker SM. 2015. New developments at EHP. Environ Health Perspect 123(4):A78; http://dx.doi.org/10.1289/ehp.1509968 Published online 1 April 2015 In the original version of this editorial Shaun Halloran’s previous employer was incorrectly stated as the American Society of Chemical Engineers. Mr. Halloran was employed by the American Society of Civil Engineers before coming to EHP. EHP regrets the error. (Source: EHP Research)
Source: EHP Research - June 1, 2015 Category: Environmental Health Authors: Web Admin Tags: Erratum June 2015 Source Type: research

Air Quality and Climate Change: A Delicate Balance
Background image: © Elenamiv/Shutterstock John H. Tibbetts, based in Charleston, SC, is former editor of Coastal Heritage, the magazine of the South Carolina Sea Grant Consortium. About This Article open Citation: Tibbetts JH. 2015. Air quality and climate change: a delicate balance. Environ Health Perspect 123:A148–A153; http://dx.doi.org/10.1289/ehp.123-A148 News Topics: Air Pollution, Allergies, Asthma, Cardiovascular Health, Climate Change, Combustion Emissions, Dust, Natural Disasters, Ozone, Particulate Matter (PM), Pollen, Mold and Mycotoxins, Respiratory Health, Temperature, Weather Processes Publishe...
Source: EHP Research - June 1, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured Focus News Air Pollution Allergies Asthma Cardiovascular Health Climate Change Combustion Emissions Dust June 2015 Mold and Mycotoxins Natural Disasters Ozone Particulate Matter (PM) Pollen Respiratory Health Tem Source Type: research

Pediatric Vaccines and Neurodevelopment: Primate Study Finds No Adverse Behavioral Effects
Julia R. Barrett, MS, ELS, a Madison, WI–based science writer and editor, is a member of the National Association of Science Writers and the Board of Editors in the Life Sciences. About This Article open Citation: Barrett JR. 2015. Pediatric vaccines and neurodevelopment: primate study finds no adverse behavioral effects. Environ Health Perspect 123:A156; http://dx.doi.org/10.1289/ehp.123-A156 News Topics: Infectious Disease, Mental Health, Mercury, Neurologic Health Published: 1 June 2015 PDF Version (320 KB) Related EHP Article Examination of the Safety of Pediatric Vaccine Schedules in a Non-Human ...
Source: EHP Research - June 1, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Infectious Disease June 2015 Mental Health Mercury Neurologic Health Source Type: research

Comparing BPS and BPA: Cardiovascular Effects in Female Rat Hearts
Nate Seltenrich covers science and the environment from Petaluma, CA. His work has appeared in High Country News, Sierra, Yale Environment 360, Earth Island Journal, and other regional and national publications About This Article open Citation: Seltenrich N. 2015. Comparing BPS and BPA: cardiovascular effects in female rat hearts. Environ Health Perspect 123:A157; http://dx.doi.org/10.1289/ehp.123-A157 News Topics: Bisphenol A (BPA), Cardiovascular Health, Endocrine Disruptors Published: 1 June 2015 PDF Version (374 KB) Related EHP Article Rapid Responses and Mechanism of Action for Low-Dose Bisphenol S on ex V...
Source: EHP Research - June 1, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Bisphenol A (BPA) Cardiovascular Health Endocrine Disruptors June 2015 Source Type: research

Exercising in Polluted Areas: Study Suggests Benefits Outweigh the Health Risks of NO2 Exposure
Nancy Averett writes about science and the environment from Cincinnati, OH. Her work has been published in Pacific Standard, Audubon, Discover, E/The Environmental Magazine, and a variety of other publications. About This Article open Citation: Averett N. 2015. Exercising in polluted areas: study suggests benefits outweigh the health risks of NO2 exposure. Environ Health Perspect 123:A158; http://dx.doi.org/10.1289/ehp.123-A158 News Topics: Air Pollution, Urban Issues, Respiratory Health Published: 1 June 2015 PDF Version (661 KB) Related EHP Article A Study of the Combined Effects of Physical Activity and Air ...
Source: EHP Research - June 1, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Air Pollution June 2015 Respiratory Health Urban Issues Source Type: research

Examining Mixtures of Disinfection By-Products: Rat Study Shows No Effects on Reproduction
Lindsey Konkel is a Worcester, MA–based journalist who reports on science, health, and the environment. About This Article open Citation: Konkel L. 2015. Examining mixtures of disinfection by-products: rat study shows no effects on reproduction. Environ Health Perspect 123:A159; http://dx.doi.org/10.1289/ehp.123-A159 News Topics: Disinfection By-Products (DBPs), Drinking Water Quality, Reproductive Health, Water Treatment Published: 1 June 2015 PDF Version (469 KB) Related EHP Article Reproductive Toxicity of a Mixture of Regulated Drinking-Water Disinfection By-Products in a Multigenerational Rat Bioassa...
Source: EHP Research - June 1, 2015 Category: Environmental Health Authors: Web Admin Tags: Featured News Science Selection Disinfection By-Products (DBPs) Drinking Water Quality June 2015 Reproductive Health Water Treatment Source Type: research

Acrolein Exposure in U.S. Tobacco Smokers and Non-Tobacco Users: NHANES 2005-2006
Author Affiliations open Tobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, Georgia, USA PDF Version (747 KB) Abstract About This Article Supplemental Material Article-Level Metrics Background: Acrolein is a highly reactive α, β unsaturated aldehyde and respiratory irritant. Acrolein is formed during combustion (e.g. burning tobacco or biomass), during high-temperature cooking of foods, and in vivo as a product of oxidative stress and polyamine metabolism. No biomonitoring reference data has been...
Source: EHP Research - May 29, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Reducing Periconceptional Methylmercury Exposure: Cost–Utility Analysis for a Proposed Screening Program for Women Planning a Pregnancy in Ontario, Canada
Conclusions: Our findings suggest that the proposed periconceptional blood mercury screening program for women planning a pregnancy would be highly cost-effective from a societal perspective. The results of a value of information analysis confirm the robustness of the study’s conclusions. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used i...
Source: EHP Research - May 29, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

Smoking-Associated DNA Methylation Biomarkers and Their Predictive Value for All-Cause and Cardiovascular Mortality
Conclusion: The novel methylation biomarkers are highly informative for both smoking exposure and smoking-related mortality outcomes. In particular, these biomarkers may substantially improve cardiovascular risk prediction. Nevertheless, the findings of the present study need to be further validated in additional large longitudinal studies. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as...
Source: EHP Research - May 27, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

In Vitro Effects of Bisphenol A β-D-Glucuronide (BPA-G) on Adipogenesis in Human and Murine Preadipocytes
Conclusions: To our knowledge, this study is the first to show that BPA-G induces adipocyte differentiation and is not simply an inactive metabolite. The fact that BPA-G induces adipogenesis and is inhibited by an ER antagonist yet has no estrogenic activity suggests that it has no classical ER transcriptional activation function and acts through a pathway that remains to be determined. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with ...
Source: EHP Research - May 27, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Vehicular Traffic-Related Polycyclic Aromatic Hydrocarbon Exposure and Breast Cancer Incidence: The Long Island Breast Cancer Study Project (LIBCSP)
Conclusions: In our population-based study, we observed positive associations between vehicular traffic-related B[a]P exposure and breast cancer incidence among women with comparatively high long-term traffic B[a]P exposures, although effect estimates were imprecise. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be ...
Source: EHP Research - May 22, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Research Article Source Type: research

Prepubertal Serum Concentrations of Organochlorine Pesticides and Age at Sexual Maturity in Russian Boys
Author Affiliations open 1Environmental and Occupational Medicine and Epidemiology Program, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; 2Quintiles, Cambridge, Massachusetts, USA; 3Departments of Biostatistics and 4Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA; 5Pediatric Endocrine Division, Departments of Pediatrics and 6Cell and Developmental Biology, University of Massachusetts Medical School, Worcester, Massachusetts, USA; 7Channing Division of Network Medicine, Department of Medicine, Brig...
Source: EHP Research - May 22, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Children's Health Source Type: research

A Unified Probabilistic Framework for Dose–Response Assessment of Human Health Effects
Conclusions: While some implementation challenges remain, this unified probabilistic framework can provide substantially more complete and transparent characterization of chemical hazards and support better-informed risk management decisions. This EHP Advance Publication article has been peer-reviewed, revised, and accepted for publication. EHP Advance Publication articles are completely citable using the DOI number assigned to the article. This document will be replaced with the copyedited and formatted version as soon as it is available. Through the DOI number used in the citation, you will be able to access this docum...
Source: EHP Research - May 22, 2015 Category: Environmental Health Authors: Sam Duvall Tags: Review Source Type: research