Prevalence of depression among subjects with and without gestational diabetes mellitus in Bangladesh: a hospital based study.
CONCLUSION: Higher rate of depression in pregnancy deserves medical attention especially women diagnosed with GDM. Further studies should estimate adverse pregnancy outcome for untreated depression especially in GDM cases.
PMID: 26221580 [PubMed] (Source: Diabetes Metab)
Source: Diabetes Metab - July 31, 2015 Category: Endocrinology Authors: Natasha K, Hussain A, Khan AK Tags: J Diabetes Metab Disord Source Type: research
Skeletal muscle to pancreatic β-cell cross-talk: the effect of humoral mediators liberated by muscle contraction and acute exercise on β-cell apoptosis.
CONCLUSIONS: Unidentified circulating humoral mediators released during exercise prevent proinflammatory cytokine-induced β-cell apoptosis. Muscle-derived mediators released during exercise suppress β-cell insulin secretion. Furthermore, muscle-derived IL-6 appears to prevent β-cell apoptosis under normal conditions but contributes to β-cell apoptosis under proinflammatory conditions.
PMID: 26218753 [PubMed - as supplied by publisher] (Source: Diabetes Metab)
Source: Diabetes Metab - July 28, 2015 Category: Endocrinology Authors: Christensen CS, Christensen DP, Lundh M, Dahllöf MS, Haase TN, Velasquez JM, Laye MJ, Mandrup-Poulsen T, Solomon TP Tags: J Clin Endocrinol Metab Source Type: research
Neuroendocrine morbidity after pediatric optic gliomas: a longitudinal analysis of 166 children over 30 years.
CONCLUSIONS: This first longitudinal OP/HSG-specific study demonstrates that hypothalamo-pituitary dysfunction evolves hierarchically over decades. Tumor location predicts its speed of onset and radiotherapy its density. GnD can evolve from previous CPP, whilst life-threatening PPD can occur after any surgery. Our data suggest that recent radiation-avoiding chemotherapeutic strategies have increased GHD without improving survival.
PMID: 26218754 [PubMed - as supplied by publisher] (Source: Diabetes Metab)
Source: Diabetes Metab - July 28, 2015 Category: Endocrinology Authors: Gan HW, Phipps K, Aquilina K, Gaze MN, Hayward R, Spoudeas HA Tags: J Clin Endocrinol Metab Source Type: research
Determine the relationship between perceived social support and depression level of patients with diabetic foot.
CONCLUSIONS: In the treatment and care of the patients with diabetic foot; anxiety and depression status of the patients, as well as physical status, should also be evaluated routinely. The individuals provided to take professional care.
PMID: 26203429 [PubMed] (Source: Diabetes Metab)
Source: Diabetes Metab - July 26, 2015 Category: Endocrinology Authors: Yildiz E, Aşti T Tags: J Diabetes Metab Disord Source Type: research
Prevalence and factors associated with metabolic syndrome among Tamils aged over 18 years in Jaffna district, Sri Lanka.
CONCLUSION: One out of four had MS. Old age, urban living and smoking carried higher risk for developing MS in Jaffna community.
PMID: 26203430 [PubMed] (Source: Diabetes Metab)
Source: Diabetes Metab - July 26, 2015 Category: Endocrinology Authors: Amarasinghe S, Balakumar S, Arasaratnam V Tags: J Diabetes Metab Disord Source Type: research
The association of vitamin D deficiency with psychiatric distress and violence behaviors in Iranian adolescents: the CASPIAN-III study.
CONCLUSION: Some psychiatric distress such as anger, anxiety, poor quality sleep, depression, and worry are associated with hypovitaminosis D in adolescents. The clinical significance of the current findings should be determined in future longitudinal studies.
PMID: 26203431 [PubMed] (Source: Diabetes Metab)
Source: Diabetes Metab - July 26, 2015 Category: Endocrinology Authors: Ataie-Jafari A, Qorbani M, Heshmat R, Ardalan G, Motlagh ME, Asayesh H, Arzaghi SM, Tajadini MH, Nejatinamini S, Poursafa P, Kelishadi R Tags: J Diabetes Metab Disord Source Type: research
Evaluation of fetal cell transplantation safety in treatment of diabetes: a three-year follow-up.
CONCLUSIONS: Findings of our study demonstrated that stem cell transplantation can be considered a relatively safe procedure apart from one case of meningioma; it did neither cause any life-threatening complications nor increased the rate of the diabetes micro- and macrovascular complications.
PMID: 26207222 [PubMed] (Source: Diabetes Metab)
Source: Diabetes Metab - July 26, 2015 Category: Endocrinology Authors: Nasli-Esfahani E, Ghodsi M, Amini P, Keshtkar AA, Amiri S, Mojahed-Yazdi N, Tootee A, Larijani B Tags: J Diabetes Metab Disord Source Type: research
Impact of a novel 14 bp MEN1 deletion in a patient with hyperparathyroidism and gastrinoma.
We report a novel 14 bp MEN1 deletion mutation in a 35-year-old female with history of recurrent epigastric pain, vomiting, loose stools and weight loss. On evaluation she was diagnosed to have multifocal gastro-duodenal gastrinoma with paraduodenal lymph nodes and solitary liver metastasis. She was also found to have primary hyperparathyroidism with bilateral inferior parathyroid adenoma. Pancreatico-duodenectomy with truncalvagotomy was performed. Four months later, radiofrequency ablation (RFA) of segment 4 of the liver was done followed by three and a half parathyroidectomy. MEN1 screening was carried out for the pat...
Source: Diabetes Metab - July 24, 2015 Category: Endocrinology Authors: Birla S, P Jyotsna V, Singla R, Tripathi M, Sharma A Tags: Endocrinol Diabetes Metab Case Rep Source Type: research
Severe hypercalcemia and hypernatremia in a patient treated with canagliflozin.
We report on a 60-year-old man with uncontrolled type 2 diabetes treated with insulin, glimepiride, metformin and canagliflozin, who was admitted with altered mental status after a syncopal episode. He had a 1-week history of ingestion of Tums for heartburn followed by poor appetite and lethargy. Laboratory work-up showed acute kidney injury, diabetic ketoacidosis (DKA), and parathyroid hormone-independent severe hypercalcemia of 17.4 mg/dl. DKA resolved with insulin treatment, and saline hydration led to improvement in hypercalcemia and renal function over 48 h, but was accompanied by a rapid increase in the serum sod...
Source: Diabetes Metab - July 24, 2015 Category: Endocrinology Authors: Kaur A, Winters SJ Tags: Endocrinol Diabetes Metab Case Rep Source Type: research
Fructose Metabolism and Relation to Atherosclerosis, Type 2 Diabetes, and Obesity.
Abstract
A high intake of sugars has been linked to diet-induced health problems. The fructose content in sugars consumed may also affect health, although the extent to which fructose has a particularly significant negative impact on health remains controversial. The aim of this narrative review is to describe the body's fructose management and to discuss the role of fructose as a risk factor for atherosclerosis, type 2 diabetes, and obesity. Despite some positive effects of fructose, such as high relative sweetness, high thermogenic effect, and low glycaemic index, a high intake of fructose, particularly ...
Source: Diabetes Metab - July 24, 2015 Category: Endocrinology Authors: Kolderup A, Svihus B Tags: J Nutr Metab Source Type: research
Ethnic differences in effects of maternal pre-pregnancy and pregnancy adiposity on offspring size and adiposity.
CONCLUSIONS: ppBMI and GWG are independent modifiable factors for child size and adiposity up to two years of age. The associations are ethnic-dependent, and underscore the importance of ethnic specific studies before generalizing the applicability of risk factors reported in other populations.
PMID: 26200236 [PubMed - as supplied by publisher] (Source: Diabetes Metab)
Source: Diabetes Metab - July 22, 2015 Category: Endocrinology Authors: Lin X, Aris IM, Tint MT, Soh SE, Godfrey KM, Yeo GS, Kwek K, Chan JK, Gluckman PD, Chong YS, Yap F, Holbrook JD, Lee YS, GUSTO study group Tags: J Clin Endocrinol Metab Source Type: research
Steroid sex hormones, sex hormone binding globulin and diabetes incidence in the Diabetes Prevention Program.
CONCLUSIONS: Estrogens and testosterone predicted diabetes risk in men but not in women. SHBG and its polymorphisms did not predict risk in men or women. Diabetes risk is more potently determined by obesity and glycemia than by sex hormones.
PMID: 26200237 [PubMed - as supplied by publisher] (Source: Diabetes Metab)
Source: Diabetes Metab - July 22, 2015 Category: Endocrinology Authors: Mather KM, Kim C, Christophi CA, Aroda VR, Knowler WC, Edelstein SE, Florez JC, Labrie F, Kahn SE, Goldberg RB, Barrett-Connor E, Diabetes Prevention Program Research Group Tags: J Clin Endocrinol Metab Source Type: research
PTH(1-34) for surgical hypoparathyroidism: a prospective open label investigation of efficacy and quality of life.
CONCLUSION: this is the largest study that demonstrates the effectiveness of PTH(1-34) in the treatment of adult patients with post-surgical hypoparathyroidism and it shows that PTH(1-34) may improve mental and physical health in hypoparathyroid subjects.
PMID: 26196949 [PubMed - as supplied by publisher] (Source: Diabetes Metab)
Source: Diabetes Metab - July 21, 2015 Category: Endocrinology Authors: Santonati A, Palermo A, Maddaloni E, Bosco D, Spada A, Grimaldi F, Raggiunti B, Volpe R, Manfrini S, Vescini F, Hypoparathyroidism AME group Tags: J Clin Endocrinol Metab Source Type: research
Vitamin D associations with renal, bone, and cardiovascular phenotypes: African American-Diabetes Heart Study.
CONCLUSIONS: In contrast to BAVD and 25OHD, only 1,25OH2D levels were significantly and inversely associated with changes in subclinical atherosclerosis and albuminuria in African Americans, suggesting potential beneficial effects.
PMID: 26196951 [PubMed - as supplied by publisher] (Source: Diabetes Metab)
Source: Diabetes Metab - July 21, 2015 Category: Endocrinology Authors: Freedman BI, Divers J, Russell GB, Palmer ND, Wagenknecht LE, Smith SC, Xu J, Carr JJ, Bowden DW, Register TC Tags: J Clin Endocrinol Metab Source Type: research
Early increases in plasma bile acids post Roux-en-Y gastric bypass are driven by insulin sensitizing, secondary bile acids.
CONCLUSIONS: Overall findings suggest that bacterially derived bile acids may mediate the early improvements at one month after RYGB. Future studies should examine the changes in specific bile acid chemical species following bariatric procedures and bile acid-specific signaling changes.
PMID: 26196952 [PubMed - as supplied by publisher] (Source: Diabetes Metab)
Source: Diabetes Metab - July 21, 2015 Category: Endocrinology Authors: Albaugh VL, Flynn CR, Cai S, Xiao Y, Tamboli RA, Abumrad NN Tags: J Clin Endocrinol Metab Source Type: research
