PS152 Ivabradine in Patients With Non-ST Elevation Acute Coronary Syndrome and Primary Percutaneous Intervention. Valeria: A Pilot Study
Non-ST elevation acute coronary syndrome (NSTE-ACS) is the commonest acute presentation of coronary artery disease. Despite an increase in the rate of primary percutaneous coronary intervention (PCI), medical therapy continues to retain a central rol in the treatment of these frail patients and heart rate (HR) at discharge correlates with mortality. Ivabradine is a pure HR reducing agent that has no effect on blood pressure and increases coronary flow reserve, being a new option that could improve the prognosis of this population. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: F.A. Reyes, F.G. Padilla, F.J. Robles Tags: Poster Abstract Source Type: research
PS153 Management of Unprotected Left Main Acute Coronary Syndrome: A Systematic Literature Review
Studies comparing percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) in the elective setting amongst patients with unprotected left main disease (ULM) have shown both to be equally effective. However, there is limited data on the outcomes of these interventions in the setting of acute coronary syndrome (ACS). (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: K.R. Saripalli, J. Yap, K.K. Yeo Tags: Poster Abstract Source Type: research
PS154 Assessment of the Myocardial Performance Index in Patients With First Acute Myocardial Infarction
Left ventricular function estimated from 2D echocardiography correlates well with measurements from angiography and is useful in establishing prognosis after acute myocardial infarction (AMI). Further, a measure of left ventricular global myocardial performance combining systolic and diastolic function could be most useful in the assessment of cardiac function. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: J. Vincelj, A. Bari šin, L. Bitar, S. Jakšić Jurinjak, D. Horvat, S. Barišin, Z. Sonicki Tags: Poster Abstract Source Type: research
PS155 Effects of Ischemic Postconditioning on Sizes of Myocardial Infarction Induced by Ischemia/Reperfusion and Toll-R4 Expression in Rats
The effects of ischemic postconditioning on the sizes of myocardial infarction induced by ischemia/reperfusion(I/R) and expression of Toll-R4 in rats myocardium. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: Y. Wang Tags: Poster Abstract Source Type: research
PS156 Ecls Instead of Iabp in Acute Coronary Syndrome and Cardiogenic Shock – Promising Preliminary Results After 2 Years of Single Center Experience
Due to the high mortality rate, the therapy of patients (PTS) with an acute coronary syndrome (ACS) and cardiogenic shock (CS) remains still a challenge. Over many years in such setting we used an intra-aortic balloon pump system (IABP), but with disappointing results. After the publication of the SHOCK II – trial we decided to change our strategy and started to use an extracorporeal circulatory life support (ECLS). (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: M. Zadura, F. Szigat, B. Hejazin, P. Szigat, R. Bittner, C. Bischoff, W. Motz Tags: Poster Abstract Source Type: research
PS157 The Relationship Between Heart Rate Recovery and the Levels of Catestatin After Acute Myocardial Infarction
Autonomic nervous dysfunctions are closely related to the occurrence, development and prognosis of acute myocardial infarction (AMI). Heart rate recovery after exercise (HRR)is a common clinical evaluated index of autonomic nervous function, which reflects autonomic balance under treadmill exercise. Our preliminary study showed that plasma levels of catestatin (CST) were increased gradually, and inversely associated with norepinephrine during the early phase of AMI, which indicated that CST might play an important role in regulation of autonomic nervous system after AMI. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: W. Zhao, Y. Liu, L. Zu, W. Gao Tags: Poster Abstract Source Type: research
PS158 Determinants of Heart Rate Recovery for Patients With Primary PCI After ST-Elevation Myocardial Infarction
The majority of patients with acute myocardial infarction (AMI) are associated with autonomic nervous dysfunctions, which are closely related to the prognosis of AMI. Heart rate recovery after exercise (HRR) is a common clinical evaluated index of autonomic nervous function. However there are few studies about the determinants of HRR. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: W. Zhao, Y. Liu, L. Zu, W. Gao Tags: Poster Abstract Source Type: research
PS160 Inflammatory Thoracic Aortic Aneurysms and Dissections
Aortic aneurysms represent one of the major causes of cardiovascular surgery. Their etiology varies greatly based on patient ’s age and other clinicopathologic determinants. In addition to common atherosclerotic vascular diseases, an inflammatory etiology, in particular IgG4-related disease (IgG4-RD) has increasingly emerged as a cause of dissecting inflammatory aortic aneurysms (IAA). (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: T. Strecker, A. Agaimy, M. Weyand Tags: Poster Abstract Source Type: research
PS162 Integrating Pro-Bnp and Pedometer to the 6MWT in Patients With PH in Public Hospital Center of Argentina
The walk test six minutes, as we all know, is a prognostic marker, both at the time of diagnosis, and monitoring and adjusting the treatment, which is why the goal of our work is to search an index into this test that allows us definer of more accurate manner, in accordance with not only the parameters measured in a standardized way but add a count steps (pedometer) and proBNP levels at the time when performing the test. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: V. Gregorietti, S. Perrone, A. Machain, R. Gamboa, C. Tajer, A. Estevez, D. Aimone, R. Sarmiento, Grupo de estudio y Tratamiento de Hipertension Pulmonar Hospital El Cruce Tags: Poster Abstract Source Type: research
PS163 Tenascin-C Levels and Clinical Importance in Pulmonary Arterial Hypertension Associated With Congenital Heart Disease
In Pulmonary arterial hypertension (PAH), prognostic value of some biomarkers like BNP/NT-proBNP has been shown and used in the routine course of the disease. Tenascin-C (TNC) is an extracellular matrix glycoprotein and has a great importance in the pathophysiology of PAH, but clinical relevance is unknown. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: O. Vuran, M. Kayikcioglu, S. Nalbantgil, O. Musayev, H.S. Kemal, N. Mogulkoc, L.C. Hurkan, H. Kultursay Tags: Poster Abstract Source Type: research
PS164 Underdosing of Noacs for AF: Old Habits Die Hard
Many physicians hold a bias against anticoagulation for atrial fibrillation (AF) on account of their perception of unacceptably high bleeding risk for their patient. This risk-averse tendency with fear of bleeding may be responsible for underdosing with warfarin ( “low-intensity anticoagulation”) despite a proven lack of efficacy without improved safety with this strategy. Whilst underdosing with warfarin is common, there is little known about the extent of non-Vitamin K antagonist (VKA) anticoagulant (NOAC) underdosing in contemporary practice. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: T.J. Ford, A. Cheng, G. Youssef, M. Sader, D. Rees Tags: Poster Abstract Source Type: research
PS165 Alirocumab Efficacy is Independent of Background Statin Type or Dose
Statins increase PCSK9 plasma levels, which may potentially affect alirocumab efficacy due to partial elimination via PCSK9-mediated clearance. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: A.L. Catapano, L.V. Lee, M.J. Louie, D. Thompson, J. Bergeron Tags: Poster Abstract Source Type: research
PS166 Efficacy and Safety of Alirocumab According to Smoking Status
Studies have suggested that smokers have higher circulating levels of PCSK9 than non-smokers. We analyzed whether differential effects were seen with alirocumab treatment in smokers and non-smokers. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: A.C. Sposito, F.A. Fonseca, M. Averna, L.V. Lee, M.J. Louie, G. Asset, M. Farnier Tags: Poster Abstract Source Type: research
PS168 Captopril Therapeutic Drug Monitoring in Paediatric Patients With Heart Failure: Comparison of Individuals With and Without Complex Congenital Pathologies
Within the recommended dosage range for any given drug, the individual clinical response of patients varies widely, this being particularly true in paediatrics. Whereas some genotype-response relationships have been identified, it is yet unknown whether and how do complex genetic disturbances affect drug metabolism. As part of a therapeutic drug monitoring (TDM) study of captopril to control heart failure (HF), we hypothesized that complex congenital pathologies might have an influence in its pharmacokinetics, and thus in clinical response. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: M.J. Flores P érez, A.B. Noriega Jalil, A.M.D.C. Flores Pérez, L. Rivera Espinosa, H. Osnaya Martínez, L. Camacho Reyes, A. Bobadilla Aguirre Tags: Poster Abstract Source Type: research
PS170 Oxidative Stress and Inflammation in Blood and Coronary Thrombus in Acute Myocardial Infarction: Results of the Arteria Study
Thrombus formation is a dynamic process regulated by flow, oxidative stress and inflammation. (Source: CVD Prevention and Control)
Source: CVD Prevention and Control - May 31, 2016 Category: Global & Universal Authors: A. Dominguez-Rodriguez, P. Abreu-Gonzalez, L. Consuegra-Sanchez, P. Avanzas, A. Sanchez-Grande, P. Conesa-Zamora Tags: Poster Abstract Source Type: research
