Deep brain stimulation for Parkinson ’s disease: how to select candidates for pallidal or subthalamic stimulation
This article presents a review of recent reports that describe follow-up results and double-blind studies on the signs for r elief of each type of parkinsonian symptom, following GPi or STN stimulation. It also includes a discussion of how further research should be organized in order to identify whether GPi or STN stimulation exerts the greatest effect on particular kinds of parkinsonian symptoms. (Source: Critical Reviews in Neurosurgery)
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
Radiation therapy for gliomas
We present several studies related to the effects of radiation on normal brain and gliomas. One paper suggests a mechanism of radiation-induced reproductive failure that is separate from mitotic cell death and apoptosis. Others describe changes in cytokine regulation and receptor density. After irradiation, necrosis of normal tissue can be indistinguishable from recurrence of the tumor with conventional studies. However, functional imaging can differentiate between neoplasm and functional alterations in tissue due to radiation. While much more work must be done in this field, these papers indicate that radiation therapy re...
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
Spinal cord stimulation for the treatment of refractory angina pectoris
AbstractAngina pectoris resulting from coronary artery disease and myocardial ischemia affects millions of patients worldwide. A significant number of patients suffer from intractable angina despite maximal pharmacological and surgical therapy. For this subset of patients, the treatment options are few and the condition extremely disabling. Spinal cord stimulation (SCS) has traditionally been employed for the treatment of a wide variety of painful conditions such as failed back surgery, reflex sympathetic dystrophy, and nerve injury pain. Over the past decade, SCS has gained popularity as a potential therapy for patients w...
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
Deep brain stimulation for Parkinson ’s disease: how to select candidates for pallidal or subthalamic stimulation
This article presents a review of recent reports that describe follow-up results and double-blind studies on the signs for r elief of each type of parkinsonian symptom, following GPi or STN stimulation. It also includes a discussion of how further research should be organized in order to identify whether GPi or STN stimulation exerts the greatest effect on particular kinds of parkinsonian symptoms. (Source: Critical Reviews in Neurosurgery)
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
Vestibular schwannoma
AbstractThe state of the art of vestibular schwannoma management is reviewed with discussion of pertinent literature to bring out the current results and controversies in this field. Microsurgery results from four major series are discussed along with data from those using gamma knife or linear accelerators to treat these tumors. (Source: Critical Reviews in Neurosurgery)
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
Radiosurgery for metastatic brain tumors
AbstractSince the life span of patients with metastatic brain tumors is quite limited, the aim of the treatment is to prolong their useful quality of life with minimally invasive therapeutic modalities. Although gamma knife radiosurgery (GKR) is widely used and accepted as a standard therapeutic modality for treating metastatic brain tumors today, there are still several problems to be clarified. The indication of GKR for metastatic brain tumors is based on the size, number of metastases, the state of primary cancer, systemic metastases, general condition of the patient, the radiosensitivity of primary cancer, the effectiv...
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
Papers reviewed in this issue
(Source: Critical Reviews in Neurosurgery)
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
Diffuse axonal injury: its role in diffuse brain injury and its significance for severe disability and vegetative state
AbstractDiffuse traumatic brain injury and combinations of diffuse with focal impact traumatic brain injury can cause widespread diffuse axonal injury (DAI) to the white matter. DAI is often the main reason for a persistent vegetative state or a persistent dementia after acute brain damage and may be responsible for a poor outcome after neurosurgical interventions. In the last few years, amyloid precursor protein (APP) has attracted interest as an early marker of DAI staining only injured axons, whereas background uninjured axons are not stained, in contrast to the more traditional demonstration of DAI by neurofilament pro...
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
Interventional neuroradiology
AbstractIn this review, papers have been selected with the object of informing the reader about research developed by interventional neuroradiologists to improve the quality of materials, to further knowledge of their performance and use, to search for new items, and to follow-up and check therapeutic results. Animal models, in-vitro models, and special applications of technical possibilities are described and discussed with interesting and promising results. (Source: Critical Reviews in Neurosurgery)
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
Concussion confusion
AbstractThe literature on concussion contains elements of confusion in that the word is used for cases in which there is obviously permanent neuronal damage. In turn, this leads to confusion regarding the prognosis and immediate management of cases where a blow to the head is the primary injury. If we adhere to the classic definition of concussion, “a transient disturbance of neurologic function with no structural damage”, a lot of this confusion will disappear, including that surrounding prolonged post-concussion syndrome (PPCS), second impact syndrome (SIS), and predisposition to become concussed. (Source: Critical R...
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
Cervical spinal trauma
AbstractOver the past years, significant advances have taken place in basic research, imaging, and in the treatment of cervical spine injuries. The pathophysiological understanding of spinal cord injury has been considerably improved by basic research. Spinal cord damage occurs as a result of primary mechanical insult of secondary ischemic and biochemical tissular alterations. Twenty percent of patients with a major spine injury will have a second spine injury at another level. Such lesions include arterial dissections. These patients often suffer simultaneous but unrelated chest or abdominal injuries. Current management o...
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
Publications scanned for pertinent articles
(Source: Critical Reviews in Neurosurgery)
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
Radiation therapy for gliomas
We present several studies related to the effects of radiation on normal brain and gliomas. One paper suggests a mechanism of radiation-induced reproductive failure that is separate from mitotic cell death and apoptosis. Others describe changes in cytokine regulation and receptor density. After irradiation, necrosis of normal tissue can be indistinguishable from recurrence of the tumor with conventional studies. However, functional imaging can differentiate between neoplasm and functional alterations in tissue due to radiation. While much more work must be done in this field, these papers indicate that radiation therapy re...
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
Spinal cord stimulation for the treatment of refractory angina pectoris
Abstract
Angina pectoris resulting from coronary artery disease and myocardial ischemia affects millions of patients worldwide. A significant number of patients suffer from intractable angina despite maximal pharmacological and surgical therapy. For this subset of patients, the treatment options are few and the condition extremely disabling. Spinal cord stimulation (SCS) has traditionally been employed for the treatment of a wide variety of painful conditions such as failed back surgery, reflex sympathetic dystrophy, and nerve injury pain. Over the past decade, SCS has gained popularity as a potential t...
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
Deep brain stimulation for Parkinson’s disease: how to select candidates for pallidal or subthalamic stimulation
This article presents a review of recent reports that describe follow-up results and double-blind studies on the signs for relief of each type of parkinsonian symptom, following GPi or STN stimulation. It also includes a discussion of how further research should be organized in order to identify whether GPi or STN stimulation exerts the greatest effect on particular kinds of parkinsonian symptoms. (Source: Critical Reviews in Neurosurgery)
Source: Critical Reviews in Neurosurgery - September 1, 2000 Category: Neurosurgery Source Type: research
