Physical activity across the curriculum (PAAC3): Testing the application of technology delivered classroom physical activity breaks
Only 43% of children in the U.S., ages 6 –11 yrs., meet current physical activity (PA) guidelines. To satisfy the MVPA requirement, schools have begun incorporating MVPA in the form of activity breaks or MVPA academic lessons. We completed two, 3 academic-yr. cluster randomized trials (DK61489, DK85317) called “Physical Activity Acro ss the Curriculum” (PAAC) which involved increasing MVPA in the classroom. Across 3-yrs. teachers in PAAC schools delivered ~60 min/wk. (12 min/day) of MVPA. Although short of our MVPA goal (20 min/d), the PAAC approach substantially increased in-school MVPA. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - January 28, 2020 Category: Radiology Authors: Amanda N. Szabo-Reed, Richard A. Washburn, J. Leon Greene, Lauren T. Ptomey, Anna Gorczyca, Robert H. Lee, Todd D. Little, Jaehoon Lee, Jeff Honas, Joseph E. Donnelly Source Type: research
Corrigendum to “Rationale and design of the Study To Understand Fall Reduction and Vitamin D in You (STURDY): A randomized clinical trial of Vitamin D supplement doses for the prevention of falls in older adults” [Contemp Clin Trials. 73 (2018) 111–122]
We have identified two errors in our article: (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - January 26, 2020 Category: Radiology Authors: Erin D. Michos, Christine M. Mitchell, Edgar R. Miller, Alice L. Sternberg, Stephen P. Juraschek, Jennifer A. Schrack, Sarah L. Szanton, Jeremy D. Walston, Rita R. Kalyani, Timothy B. Plante, Robert H. Christenson, Dave Shade, James Tonascia, David L. Rot Tags: Corrigendum Source Type: research
Editorial Board
(Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - January 24, 2020 Category: Radiology Source Type: research
Adherence-adjustment in placebo-controlled randomized trials: An application to the candesartan in heart failure randomized trial
Adherence adjustment in the CHARM trial is feasible when appropriate assumptions about missing data and confounding are made. These assumptions cannot be verified but can be supported through the use of placebo-arm adherence assessment. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - January 22, 2020 Category: Radiology Authors: Eleanor J. Murray, Brian L. Claggett, Bradi Granger, Scott D. Solomon, Miguel A. Hern án Source Type: research
A behavioral activation intervention administered in a 16-week freshman orientation course: Study protocol
The transition from high school to college is a developmentally sensitive period that is high-risk for the escalation of alcohol use. Although risky drinking is a common problem among freshmen, engagement in treatment services is very low. College alcohol interventions target drinking directly at a time when students may be uninterested in changing their drinking. Approaches that indirectly target drinking may be particularly effective. Behavioral activation (BA) is an intervention that indirectly addresses mental health conditions by guiding individuals to engage in reinforcing activities that align with their values (Lej...
Source: Contemporary Clinical Trials - January 22, 2020 Category: Radiology Authors: Tera L. Fazzino, Carl W. Lejuez, Richard Yi Source Type: research
Integrating machine-generated mortality estimates and behavioral nudges to promote serious illness conversations for cancer patients: Design and methods for a stepped-wedge cluster randomized controlled trial
Patients with cancer often receive care that is not aligned with their personal values and goals. Serious illness conversations (SICs) between clinicians and patients can help increase a patient's understanding of their prognosis, goals and values. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - January 22, 2020 Category: Radiology Authors: Christopher R. Manz, Ravi B. Parikh, Chalanda N. Evans, Corey Chivers, Susan H. Regli, Justin E. Bekelman, Dylan Small, Charles A.L. Rareshide, Nina O'Connor, Lynn M. Schuchter, Lawrence N. Shulman, Mitesh S. Patel Source Type: research
High-dose rifapentine with or without moxifloxacin for shortening treatment of pulmonary tuberculosis: Study protocol for TBTC study 31/ACTG A5349 phase 3 clinical trial
Phase 2 clinical trials of tuberculosis treatment have shown that once-daily regimens in which rifampin is replaced by high dose rifapentine have potent antimicrobial activity that may be sufficient to shorten overall treatment duration. Herein we describe the design of an ongoing phase 3 clinical trial testing the hypothesis that once-daily regimens containing high dose rifapentine in combination with other anti-tuberculosis drugs administered for four months can achieve cure rates not worse than the conventional six-month treatment regimen. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - January 21, 2020 Category: Radiology Authors: Susan E. Dorman, Payam Nahid, Ekaterina V. Kurbatova, Stefan V. Goldberg, Lorna Bozeman, William J. Burman, Kwok-Chiu Chang, Michael Chen, Mark Cotton, Kelly E. Dooley, Melissa Engle, Pei-Jean Feng, Courtney V. Fletcher, Phan Ha, Charles M. Heilig, John L Source Type: research
Design of a pragmatic cluster-randomized trial comparing telehealth care and best practice clinic-based care for uncontrolled high blood pressure
Uncontrolled hypertension is the largest single contributor to all-cause and cardiovascular mortality in the U.S. population. Nurse- and pharmacist-led team-based care and telehealth care interventions have been shown to result in large and lasting improvements in blood pressure (BP); however, it is unclear how successfully these can be implemented at scale in real-world settings. It is also uncertain how telehealth interventions impact patient experience compared to traditional clinic-based care. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - January 21, 2020 Category: Radiology Authors: Karen L. Margolis, A. Lauren Crain, Anna R. Bergdall, MarySue Beran, Jeffrey P. Anderson, Leif I. Solberg, Patrick J. O'Connor, JoAnn M. Sperl-Hillen, Pamala A. Pawloski, Jeanette Y. Ziegenfuss, Dan Rehrauer, Christine Norton, Patricia Haugen, Beverly B. Source Type: research
The chronic pain skills study: Protocol for a randomized controlled trial comparing hypnosis, mindfulness meditation and pain education in veterans
To describe the protocol of a randomized controlled trial to evaluate the effectiveness and mechanisms of three behavioral interventions. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - January 7, 2020 Category: Radiology Authors: Rhonda M. Williams, Dawn M. Ehde, Melissa Day, Aaron P. Turner, Shahin Hakimian, Kevin Gertz, Marcia Ciol, Alisha McCall, Carrie Kincaid, Mark W. Pettet, David Patterson, Pradeep Suri, Mark P. Jensen Source Type: research
Study protocol: CareAvenue program to improve unmet social risk factors and diabetes outcomes- A randomized controlled trial
In this study, we will test the effectiveness of CareAvenue – an automated e-health tool that screens for unmet social risk factors and informs and activates individuals to take steps to connect to resources and engage in self-care. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - January 6, 2020 Category: Radiology Authors: Minal R. Patel, Michele Heisler, John D. Piette, Kenneth Resnicow, Peter X.K. Song, Hae Mi Choe, Julie Tobi, Alyssa Smith Source Type: research
Memory advancement by intranasal insulin in type 2 diabetes (MemAID) randomized controlled clinical trial: Design, methods and rationale
Type 2 diabetes mellitus (T2DM) accelerates brain aging and increases the risk for dementia. Insulin is a key neurotrophic factor in the brain, where it modulates energy metabolism, neurovascular coupling, and regeneration. Impaired insulin-mediated brain signaling and central insulin resistance may contribute to cognitive and functional decline in T2DM. Intranasal insulin (INI) has emerged as a potential therapy for treating T2DM-related cognitive impairment. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - January 6, 2020 Category: Radiology Authors: B. Galindo-Mendez, J.A. Trevino, R. McGlinchey, C. Fortier, V. Lioutas, P. Novak, C. Mantzoros, L. Ngo, V. Novak Source Type: research
Editorial Board
(Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - December 31, 2019 Category: Radiology Source Type: research
Response to: “Biostatistics pitfalls: Lessons learned from analysis of medical data” by Yin et al.
(Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - December 29, 2019 Category: Radiology Authors: Roman Reindl-Schwaighofer, Andreas Heinzel, Georg Heinze, Michael Kammer, Rainer Oberbauer Source Type: research
Design and sample characteristics of COordinated Oral health Promotion (CO-OP) Chicago: A cluster-randomized controlled trial
COordinated Oral health Promotion (CO-OP) Chicago is a two-arm cluster-randomized trial with a wait-list control. The primary aim is to evaluate the efficacy of an oral health community health worker (CHW) intervention to improve oral health behaviors in low-income, urban children under the age of three years. Exploratory aims will determine cost-effectiveness, and if any CHW intervention impact on child tooth brushing behaviors varies when CHWs are based out of a medical clinic compared to a community setting. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - December 29, 2019 Category: Radiology Authors: Molly A. Martin, Lacey J. Zimmerman, Genesis F. Rosales, Helen H. Lee, Nattanit Songthangtham, Oksana Pugach, Anna S. Sandoval, David Avenetti, Gizelle Alvarez, Stuart A. Gansky Source Type: research
Study protocol for a sequential multiple assignment randomized trial (SMART) to improve physical activity in employed women
We describe a SMART to determine the most effective adaptive intervention to increase physical activity (steps, moderate-to-vigorous physical activity) and improve cardiovascular health among employed women who are not regularly physically active. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - December 29, 2019 Category: Radiology Authors: Susan W. Buchholz, JoEllen Wilbur, Shannon Halloway, Michael Schoeny, Tricia Johnson, Sachin Vispute, Spyros Kitsiou Source Type: research
