Randomized controlled trial protocol for project BRIDGE: A telephone-administered motivational interviewing intervention targeting risky sexual behavior in older people living with HIV
By 2020, 70% of people living with HIV in the United States will be greater than 50 years of age. As many as 37% of sexually active older people living with HIV (OPLWH) engage in HIV transmission sexual behaviors. In spite of repeated calls for secondary prevention interventions to reduce condomless sex in OPLWH, no age-appropriate, evidence-based secondary prevention interventi ons exist for this group. Furthermore, many OPLWH face barriers to engaging in face-to-face secondary prevention services because of HIV- and age-related stigma, comorbid mental and physical health conditions that complicate travel, or geographi...
Source: Contemporary Clinical Trials - May 27, 2020 Category: Radiology Authors: Julie Kahler, Timothy G. Heckman, Ye Shen, Marilyn S. Huckans, Sarah W. Feldstein Ewing, Jeffrey T. Parsons, Alissa Phelps, Mark Sutton, Julia Holloway, Travis I. Lovejoy Source Type: research
Testing a self-directed lifestyle intervention among veterans: The D-ELITE pragmatic clinical trial
Nearly half of Veterans have obesity, fueling chronic diseases. The Department of Veterans Affairs (VA) offers an evidence-based behavioral weight management intervention called MOVE!, mostly delivered through in-person group sessions. Few eligible Veterans participate due to factors like distance and preferences, mirroring barriers in the general population. Practical alternatives to standard in-person programs are needed to improve access and engagement. A self-directed lifestyle intervention called D-ELITE —delivered through pre-recorded videos by DVD or online streaming—previously efficacious in a general primary c...
Source: Contemporary Clinical Trials - May 26, 2020 Category: Radiology Authors: Katherine D. Hoerster, Margaret Collins, David H. Au, Amber Lane, Eric Epler, Jennifer McDowell, Anna E. Bar ón, Peter Rise, Robert Plumley, Tanya Nguyen, Mary Schooler, Linnaea Schuttner, Jun Ma Source Type: research
Editorial Board
(Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - May 19, 2020 Category: Radiology Source Type: research
Integrating an online weight management program with population health management in primary care: Design, methods, and baseline data from the PROPS randomized controlled trial (partnerships for reducing overweight and obesity with patient-centered strategies)
Scalable, low-cost weight management strategies are needed in primary care. We conducted a pragmatic, cluster-randomized controlled trial to examine the effectiveness of an online weight management program integrated with population health management support. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - May 15, 2020 Category: Radiology Authors: Heather J. Baer, Barbara A. De La Cruz, Ronen Rozenblum, Nyryan V. Nolido, E. John Orav, Kristina Metzler, Jason P. Block, Florencia Halperin, Katherine D. McManus, Louis J. Aronne, Guadalupe Minero, David W. Bates Source Type: research
Corrigendum to “Study protocol: CareAvenue program to improve unmet social risk factors and diabetes outcomes - A randomized controlled trial” [Contemporary Clinical Trials 89 (2020) 105933]
The authors regret they missed to one of the authors Xu Shi by mistake. The authorship now stands corrected in this corrigendum. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - May 13, 2020 Category: Radiology Authors: Minal R. Patel, Michele Heisler, John D. Piette, Kenneth Resnicow, Peter X.K. Song, Hae Mi Choe, Xu Shi, Julie Tobi, Alyssa Smith Tags: Corrigendum Source Type: research
Rationale and study design for lifestyle intervention in preparation for pregnancy (LIPP): A randomized controlled trial
Maternal obesity increases neonatal risk for obesity and metabolic syndrome later in life. Prior attempts to break this intergenerational obesity cycle by limiting excessive gestational weight gain have failed to reduce neonatal adiposity. Alternatively, pre-conception lifestyle interventions may improve the in utero metabolic milieu during early pregnancy leading to improved fetal outcomes. This randomized controlled trial (RCT) is evaluating whether a lifestyle intervention to reduce weight and improve maternal metabolism in preparation for pregnancy (LIPP) attenuates neonatal adiposity, compared to standard medical advi...
Source: Contemporary Clinical Trials - May 9, 2020 Category: Radiology Authors: M.L. Erickson, J.M. Mey, C.L. Axelrod, D. Paul, L. Gordesky, K. Russell, H. Barkoukis, P. O'Tierney-Ginn, R.A. Fielding, J.P. Kirwan, P.M. Catalano Source Type: research
Editorial Board
(Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - April 29, 2020 Category: Radiology Source Type: research
Methodology and baseline characteristics of a randomized controlled trial testing a health care professional and peer-support program for patients with chronic obstructive pulmonary disease: The BREATHE2 study
Self-management support (SMS) for patients with COPD can improve health-related quality of life (HRQOL). However, it remains unclear what SMS strategies are most effective. Using peer support to advance self-management is promising, as peer supporters possess credibility and can serve as role models. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - April 28, 2020 Category: Radiology Authors: Aboumatar Hanan, Naqibuddin Mohammad, Neiman Joseph, Saunders Jamia, Kim Samuel, Chaudhry Hina, Garcia-Morales Emmanuel, Robinson Nancy, McBurney Marjorie, Jager Leah, Ajayi Tokunbo, Bone Lee, Chung Suna, Farrell Bernard, Joo Jin Hui, Linnell John, Pirfo Source Type: research
Medication treatment for opioid use disorder in expectant mothers (MOMs): Design considerations for a pragmatic randomized trial comparing extended-release and daily buprenorphine formulations
Opioid use disorder (OUD) in pregnant women has increased significantly in recent years. Maintaining these women on sublingual (SL) buprenorphine (BUP) is an evidence-based practice but BUP-SL is associated with several disadvantages that an extended-release (XR) BUP formulation could eliminate. The National Drug Abuse Treatment Clinical Trials Network (CTN) is conducting an intent-to-treat, two-arm, open-label, pragmatic randomized controlled trial, Medication treatment for Opioid-dependent expectant Mothers (MOMs), to compare mother and infant outcomes of pregnant women with OUD treated with BUP-XR, relative to BUP-SL. (...
Source: Contemporary Clinical Trials - April 26, 2020 Category: Radiology Authors: Theresa Winhusen, Michelle Lofwall, Hendr ée E. Jones, Christine Wilder, Robert Lindblad, Davida M. Schiff, Scott Wexelblatt, Stephanie Merhar, Sean M. Murphy, Shelly F. Greenfield, Mishka Terplan, Elisha M. Wachman, Frankie Kropp, Jeff Theobald, Mitra L Source Type: research
Risk reduction through family therapy (RRFT): Protocol of a randomized controlled efficacy trial of an integrative treatment for co-occurring substance use problems and posttraumatic stress disorder symptoms in adolescents who have experienced interpersonal violence and other traumatic events
Decades of research demonstrate that childhood exposure to traumatic events, particularly interpersonal violence experiences (IPV; sexual abuse, physical abuse, witnessing violence), increases risk for negative behavioral and emotional outcomes, including substance use problems (SUP) and posttraumatic stress disorder (PTSD). Despite this well-established link —including empirical support for shared etiological and functional connections between SUP and PTSD –the field has been void of a gold standard treatment for adolescent populations. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - April 23, 2020 Category: Radiology Authors: Austin M. Hahn, Zachary Adams, Jason Chapman, Michael McCart, Ashli J. Sheidow, Michael A. de Arellano, Carla Kmett Danielson Source Type: research
The ‘Take a Break’ game: Randomized trial protocol for a technology-assisted brief abstinence experience designed to engage lower-motivated smokers
While smoking continues to be the most preventable cause of mortality in the United States, most current smokers remain not ready to quit at any given time. Engaging these ‘motivation phase’ smokers with brief experiences to build confidence and practice skills related to cessation could lead to sooner and more successful quit attempts. Increasingly available mobile technology and gamification can be used to provide smokers with accessible and engaging support. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - April 22, 2020 Category: Radiology Authors: Daniel J. Amante, Amanda C. Blok, Catherine S. Nagawa, Jessica G. Wijesundara, Jeroan J. Allison, Sharina D. Person, Jeanne Morley, Joseph Conigliaro, Kristin M. Mattocks, Lawrence Garber, Thomas K. Houston, Rajani S. Sadasivam Source Type: research
Isradipine enhancement of virtual reality cue exposure for smoking cessation: Rationale and study protocol for a double-blind randomized controlled trial
Cigarette smoking remains a leading cause of preventable death in the United States, contributing to over 480,000 deaths each year. Although significant strides have been made in the development of effective smoking cessation treatments, most established interventions are associated with high relapse rates. One avenue for increasing the effectiveness of smoking cessation interventions is to design focused, efficient, and rigorous experiments testing engagement of well-defined mechanistic targets. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - April 22, 2020 Category: Radiology Authors: Santiago Papini, Cara C. Young, Catherine S. Gebhardt, Alex Perrone, Hitoshi Morikawa, Michael W. Otto, John D. Roache, Jasper A.J. Smits Source Type: research
Targeted assessment and context-tailored implementation of change strategies (TACTICS) to increase evidence based psychotherapy in military behavioral health clinics: Design of a cluster-randomized stepped-wedge implementation study
Despite efforts by the U.S. Department of Defense to train behavioral health (BH) providers in evidence-based psychotherapies (EBPs) for posttraumatic stress disorder (PTSD), numerous barriers limit EBP implementation. A context-tailored implementation approach called TACTICS (Targeted Assessment and Context-Tailored Implementation of Change Strategies) holds promise for increasing the use of EBPs such as prolonged exposure therapy (PE) in military treatment facilities. TACTICS combines a needs assessment, a rubric for selecting implementation strategies based on local barriers, an implementation toolkit, and external faci...
Source: Contemporary Clinical Trials - April 20, 2020 Category: Radiology Authors: Craig S. Rosen, C. Adrian Davis, David Riggs, Jeffery Cook, Alan L. Peterson, Stacey Young-McCaughan, Katherine Anne Comtois, Christopher K. Haddock, Elisa V. Borah, Katherine A. Dondanville, Erin P. Finley, Sara A. Jahnke, Walker S.C. Poston, Shannon Wil Source Type: research
Proactive health support (PaHS) – telephone-based self-management support for persons at risk of hospital admission: Study protocol for a randomized controlled trial
This article describes the protocol for Proactive Health Support: a national randomized controlled trial of telephone-based self-management support (ClinicalTrials.gov, NCT03628469). The main aim of the intervention is to reduce hospital admissions and improve quality of life at six months. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - April 18, 2020 Category: Radiology Authors: Kirstine Skov Benthien, Knud Rasmussen, Camilla Palmh øj Nielsen, Louise Hjarnaa, Maja Kjær Rasmussen, Kristian Kidholm, Berit Kjærside Nielsen, Nina Konstantin Nissen, Mia Fredens, Susanne Winther, Mette Grønkjær, Ulla Toft Source Type: research
Protocol for an embedded pragmatic clinical trial to test the effectiveness of Aliviado Dementia Care in improving quality of life for persons living with dementia and their informal caregivers
Persons living with Alzheimer's disease and related dementias (ADRD) frequently experience pain and behavioral and psychological symptoms of dementia (BPSD) which decrease quality of life (QOL) and influence caregiver burden. Home healthcare professionals however may underrecognize or lack the ability to manage BPSD. (Source: Contemporary Clinical Trials)
Source: Contemporary Clinical Trials - April 18, 2020 Category: Radiology Authors: Alycia A. Bristol, Kimberly A. Convery, Victor Sote, Catherine E. Schneider, Shih-Yin Lin, Jason Fletcher, Randall Rupper, George E. Wahlen, James E. Galvin, Abraham A. Brody Source Type: research
