Computational modeling and bioinformatic analyses of functional mutations in drug target genes in Mycobacterium tuberculosis
Publication date: Available online 19 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Pooja Singh, Salma Jamal, Faraz Ahmed, Najumu Saqib, Seema Mehra, Waseem Ali, Deodutta Roy, Nasreen Z. Ehtesham, Seyed E. Hasnain (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 20, 2021 Category: Biotechnology Source Type: research

AddictGene: an integrated knowledge base for differentially expressed genes associated with addictive substance
Publication date: Available online 19 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Leisheng Shi, Yan Wang, Chong Li, Kunlin Zhang, Quansheng Du, Mei Zhao (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 20, 2021 Category: Biotechnology Source Type: research

Rational engineering of the lccβ T. versicolor laccase for the mediator-less oxidation of large polycyclic aromatic hydrocarbons
Publication date: Available online 20 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Alessandro Chiadò, Francesca Bosco, Marco Bardelli, Luca Simonelli, Mattia Pedotti, Luca Marmo, Luca Varani (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 20, 2021 Category: Biotechnology Source Type: research

Phosphotyrosine couples peptide binding and SHP2 activation via a dynamic allosteric network
Publication date: Available online 20 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Michelangelo Marasco, John Kirkpatrick, Vittoria Nanna, Justyna Sikorska, Teresa Carlomagno (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 20, 2021 Category: Biotechnology Source Type: research

Population-level diversity-disease relationship (P-DDR) in the human microbiome associated diseases
Publication date: Available online 20 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Wendy Li, Zhanshan Sam Ma (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 20, 2021 Category: Biotechnology Source Type: research

N-Glycome and N-Glycoproteome of a Hematophagous Parasitic Nematode Haemonchus
Publication date: Available online 18 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Chunqun Wang, Wenjie Gao, Shi Yan, Xing-Quan Zhu, Xun Suo, Xin Liu, Nishith Gupta, Min Hu (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 20, 2021 Category: Biotechnology Source Type: research

Structure and evolutionary trace-assisted screening of a residue swapping the substrate ambiguity and chiral specificity in an esterase
Publication date: Available online 18 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Isabel Cea-Rama, Cristina Coscolín, Panagiotis Katsonis, Rafael Bargiela, Peter N. Golyshin, Olivier Lichtarge, Manuel Ferrer, Julia Sanz-Aparicio (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 20, 2021 Category: Biotechnology Source Type: research

CRISPR/Cas9 based genome editing for targeted transcriptional control in Triple-Negative Breast Cancer
Publication date: Available online 18 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Desh Deepak Singh, Ihn Han, Eun-Ha Choi, Dharmendra Kumar Yadav (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 20, 2021 Category: Biotechnology Source Type: research

Enzyme kinetic and binding studies identify determinants of specificity for the immunomodulatory enzyme ScpA, a C5a inactivating bacterial protease
Publication date: Available online 17 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Malgorzata Tecza, Todd F. Kagawa, Monica Jain, Jakki C. Cooney (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 18, 2021 Category: Biotechnology Source Type: research

ExVe: the knowledge base of orthologous proteins identified in fungal extracellular vesicles
Publication date: Available online 17 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Vinícius da Silva Coutinho Parreira, Letícia Graziela Costa Santos, Marcio L. Rodrigues, Fabio Passetti (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 18, 2021 Category: Biotechnology Source Type: research

The requirement of cellularity for abiogenesis
Publication date: Available online 17 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Adriano Caliari, Jian Xu, Tetsuya Yomo (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 18, 2021 Category: Biotechnology Source Type: research

ADP-ribosylation systems in bacteria and viruses
Publication date: Available online 17 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Petra Mikolčević, Andrea Hloušek-Kasun, Ivan Ahel, Andreja Mikoč (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 18, 2021 Category: Biotechnology Source Type: research

Experimental approaches for investigating ion atmospheres around nucleic acids and proteins
Publication date: Available online 17 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Binhan Yu, Junji Iwahara (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 18, 2021 Category: Biotechnology Source Type: research

Automated and Semi-Automated Enhancement, Segmentation and Tracing of Cytoskeletal Networks in Microscopic Images: A Review
Publication date: Available online 15 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Bugra Özdemir, Ralf Reski (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 16, 2021 Category: Biotechnology Source Type: research

Targeting protein-protein interaction interfaces in COVID-19 drug discovery
Publication date: Available online 15 April 2021Source: Computational and Structural Biotechnology JournalAuthor(s): Chung-ke Chang, Shan-Meng Lin, Roshan Satange, Shih-Chao Lin, Sin-Cih Sun, Hung-Yi Wu, Kylene Kehn-Hall, Ming-Hon Hou (Source: Computational and Structural Biotechnology Journal)
Source: Computational and Structural Biotechnology Journal - April 16, 2021 Category: Biotechnology Source Type: research