Sex difference in using the SCOFF questionnaire to identify eating disorder patients at a psychiatric outpatient clinic
This study aimed to examine the comparative validity of the SCOFF questionnaire for detecting ED cases in men and women in the psychiatric outpatient setting. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 13, 2014 Category: Psychiatry Authors: Chao-Yu Liu, Mei-Chih Meg Tseng, Kuan-Yu Chen, Chin-Hao Chang, Shih-Cheng Liao, Hsi-Chung Chen Source Type: research

Behavioral Activation Therapy for Return to Work in Medication-Responsive Chronic Depression with Persistent Psychosocial Dysfunction
Chronic depression is associated with significant impairment in work functioning, relationships, and health. Such impairment often persists following medication-induced remission of depressive symptoms. We adapted and tested Behavioral Activation therapy with a goal of return to work (BA-W) in subjects with chronic depression who had responded to medication treatment but remained unemployed. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 7, 2014 Category: Psychiatry Authors: David J. Hellerstein, Greg Erickson, Jonathan W. Stewart, Patrick J. McGrath, Kallio Hunnicutt-Ferguson, Sarah K. Reynolds, Donna O’Shea, Ying Chen, Amy Withers, Yuanjia Wang Source Type: research

Co-occurrence of attention-deficit hyperactivity disorder symptoms with other psychopathology in young adults: parenting style as a moderator
The extent to which parenting styles can influence secondary psychiatric symptoms among young adults with ADHD symptoms is unknown. This issue was investigated in a sample of 2,284 incoming college students (male, 50.6%), who completed standardized questionnaires about adult ADHD symptoms, other DSM-IV symptoms, and their parents’ parenting styles before their ages of 16. Among them, 2.8% and 22.8% were classified as having ADHD symptoms and sub-threshold ADHD symptoms, respectively. Logistic regression was used to compare the comorbid rates of psychiatric symptoms among the ADHD, sub-threshold ADHD and non-ADHD grou...
Source: Comprehensive Psychiatry - November 5, 2014 Category: Psychiatry Authors: Hsing-Chang Ni, Susan Shur-Fen Gau Source Type: research

A study investigating the association between compulsive buying with measures of anxiety and obsessive-compulsive behavior among internet shoppers
Compulsive buying is a chronic, repetitive behaviour that becomes a primary response to negative events and feelings. Compulsive buyers are obsessed by buying and their behavior occurs in response to negative emotions and results in a decrease in the intensity of negative emotions. Euphoria or relief from negative emotions is the most common consequences of compulsive buying. A large number of studies have investigated the association between compulsive buying and anxiety, and some studies have used the Spielberger trait-state anxiety inventory. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 5, 2014 Category: Psychiatry Authors: Weinstein A., Mezig Hila, Mizrachi S., Lejoyeux M Source Type: research

Verbal School Bullying and Life Satisfaction Among Brazilian Adolescents: Profiles of the Aggressor and the Victim
Bullying is a common occurrence in adolescence that may damage the physical and emotional health. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 5, 2014 Category: Psychiatry Authors: Júnia Maria Serra-Negra, Saul Martins Paiva, Cristiane Baccin Bendo, Lívia Bonfim Fulgêncio, Carolina Freitas Lage, Patrícia Corrêa-Faria, Isabela Almeida Pordeus Source Type: research

Hoarding and eating pathology: The mediating role of emotion regulation
Hoarding disorder is characterized by persistent difficulty discarding possessions resulting in clutter that precludes one from using living areas for their intended purposes. The limited empirical work available has suggested a strong link between hoarding and various non-psychiatric conditions, including obesity. Despite these associations, no research has examined the link between hoarding and other forms of eating pathology including symptoms associated with binge eating. Moreover, little is known about mechanisms that may account for this relationship. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 5, 2014 Category: Psychiatry Authors: Amanda M. Raines, Joseph W. Boffa, Nicholas P. Allan, Nicole A. Short, Norman B. Schmidt Source Type: research

Suicidal ideation in the context of ketamine infusion: Relationship with depression and anxiety symptom clusters
Objective: Suicide is both a leading cause of death and common reason for psychiatric emergency services. Currently, there are no approved pharmacologic treatments for emergent, acute suicidal ideation. Ketamine, an NMDA receptor antagonist, has been associated with rapid reductions in suicidal ideation after infusion (within 1hour), but the relationship of suicidal ideation response to other symptoms, such as depression and anxiety, is not known. Understanding the dynamic between ideation and affective symptoms in the context of ketamine infusion may point to clinical indications for administration in emergency settings a...
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Elizabeth D. Ballard, Jennifer Vande Voort, Dave A. Luckenbaugh, Erica M. Richards, Dawn F. Ionescu, Mark J. Niciu, Nancy E. Brutsche, Rezvan Ameli, Carlos A. Zarate Source Type: research

Depression, anxiety, and telomere length: Evidence from the National Health and Nutrition Examination Survey
Background: Telomere shortening has been hypothesized to be a marker of premature aging, in particular a marker of cumulative exposure to stress over the life course. Stress is an established cause of depression and anxiety disorders, but to date the literature on the relationship between these conditions and telomere length is mixed. The study objective was to examine the relationship between depression, anxiety and telomere length, and to assess whether this relationship is moderated by antidepressant use in a nationally-representative sample of adults. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: N. Bareis, B. Needham, B. Mezuk Source Type: research

Depression and distress in Blacks and Whites in the U.S.: Results of a systematic review
Background: The literature frequently notes inconsistent findings in Black–White mental health comparisons in the U.S.: a lower prevalence of psychiatric disorder, particularly major depression, in Blacks compared with Whites, coupled with higher psychological distress. From the vantage point of social stress theory, these findings represent a double paradox. Social stress theory, the dominant framework for interpreting associations between social location and mental health, predicts worse mental health in disadvantaged versus advantaged groups by virtue of their greater stressor exposure and fewer coping resources. ...
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: David M. Barnes Source Type: research

Investigating dimensionality and measurement bias of DSM-5 alcohol use disorder in a representative sample of the largest metropolitan area in South America
Background: Given the recent launch of a new diagnostic classification (DSM-5) for alcohol use disorders (AUD), we aimed to investigate its dimensionality and possible measurement bias in past year alcohol users who had at least 1 drink per week in the 12months prior to the interview. Data came from São Paulo Megacity Project collected between 2005 and 2007, which is part of World Mental Health Surveys. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: J.M. Castaldelli-Maia, A.G. Andrade, M.C. Viana, S.S. Martins, L.H. Andrade Source Type: research

Emotion processing across the schizotypy continuum
Background: Previous research has revealed emotional processing deficits in individuals with schizophrenia. More recently, these impairments have also been identified in individuals at risk for developing schizophrenia, though at attenuated levels. The purpose of the current study is to better define the pattern of emotional functioning across the schizotypy continuum, by examining differences between individuals with varying degrees of symptom severity. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: D.L. Demmin, T. Darcy, H. Vohra, B. Hasletine, W. Gooding, G.D. Shean Source Type: research

TMS over the left dorsolateral prefrontal cortex increases GABA concentration in the ventromedial prefrontal cortex in major depression
Background: The antidepressant mechanisms of left dorsolateral prefrontal TMS are poorly understood but may involve projections to downstream targets in the ventromedial prefrontal cortex (VMPFC). TMS modulates activity and functional connectivity within the VMPFC, but it is unknown whether TMS has specific effects on particular neuronal subtypes. Inhibitory interneurons are a potential therapeutic target. GABA levels are reduced in depressives and normalize with electroconvulsive and SSRI therapies, and TMS potentiates GABAB-neurotransmission acutely in motor cortex. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: M. Dubin, X. Mao, R. Gordon, G. Kang, C. Liston, D. Shungu Source Type: research

Explaining the link between childhood maltreatment and course of alcohol and nicotine dependence: The role of personality pathology
Background: Among those with substance dependence, persistent cases have the greatest risk for adverse medical and psychosocial consequences. We have shown that a history of childhood maltreatment increases the risk for persistent alcohol and nicotine dependence (Elliott et al., in press), but the pathway underlying this association is unknown. Personality disorders may offer an explanation, as borderline personality disorder (BPD), schizotypal personality disorder (SPD), and antisocial personality disorder (ASPD) are associated with a history of childhood maltreatment (Afifi et al., 2011), and also predict persistence of ...
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: J.C. Elliott, R.D. Goodwin, M. Stohl, M.M. Wall, K.M. Keyes, A.E. Skodol, R.F. Krueger, B.F. Grant, D.S. Hasin Source Type: research

Maternal health during pregnancy: The impact of depression and obesity on infant temperament and behavior
Background: Current research supports the growing sentiment that in-utero exposure to maternal metabolic syndromes, such as obesity, increases the risk of suboptimal development in infants. The current study attempts to evaluate the comparative impact of depression in obese and non-obese mothers, which may aid in creating more effective intervention to decrease predisposition to metabolic and neurobehavioral dysregulation among the offspring later in life. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: J. Finik, N. Huynh, J. Ly, Y. Nomura Source Type: research

Advanced paternal age and risk of psychotic-like symptoms in offspring
Background: Although schizophrenia is a rare disorder, psychotic-like symptoms are reported by up to 15% of the general population, and may indicate elevated risk for later psychosis. Parental age is an established risk factor for schizophrenia, however few studies have attempted to replicate these findings with psychotic-like symptoms. The goal of this study is to examine the relationship between parental age and risk of psychotic like symptoms in the general population. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: J. Foutz, B. Mezuk Source Type: research

What does the term “specialist” really mean?
Background: In the mental health field, the term “specialist” is ambiguous and unregulated. However, the term specialist is commonly utilized by mental health professionals. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Kimberly Glazier Source Type: research

Mental health antecedents of midlife insomnia: Evidence from a four-decade longitudinal study
Study objectives: Insomnia is a highly prevalent condition that constitutes a major public health and economic burden. However, little is known about the developmental etiology of adulthood insomnia. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Sidra J. Goldman-Mellor, Alice Gregory, Avshalom Caspi, HonaLee Harrington, Michael Parsons, Richie Poulton, Terrie E. Moffitt Source Type: research

A new measure of social hedonic capacity: The ACIPS
Background: Social hypohedonia, the reduced capacity to enjoy social interactions and interpersonal relationships, is observed in individuals at heightened risk for the later development of schizophrenia, as well as individuals experiencing depression and schizophrenia. Thus, there is increasing interest in assessing social hedonic capacity in the general population and in various diverse patient populations. The study objective was to highlight the psychometric advantages of the Anticipatory and Consummatory Interpersonal Pleasure Scale (ACIPS; Gooding & Pflum, 2014, Psychiatry Research), by demonstrating its relation...
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: D.C. Gooding, M.J. Pflum, C.L. Siggelkow Source Type: research

Epigenetic findings for PTSD and lower respiratory symptoms in male WTC responders
After the World Trade Center (WTC) attack on 9/11/2001, the CDC established a consortium of clinics (WTC-Health Programs) in the NY-metropolitan area to detect, monitor and treat WTC-related health problems occurring among responders to the disaster. More than 25% of these responders (~30,000) have WTC-related post-traumatic stress disorder (PTSD) and lower respiratory symptoms. These two conditions are often co-morbid (OR=2.5). Longitudinal findings indicate that WTC-PTSD is associated with an increased risk of new-onset respiratory disease (but not vice versa). (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Adam Gonzalez, Guia Guffanti, Andrew Ratanatharathorn, Roman Kotov, Evelyn Bromet, Karestan Koenen, Sandro Galea, Benjamin J. Luft Source Type: research

Patterns of recent alcohol consumption by race among a sample of urban men who have sex with men
Introduction: Research in the general population consistently finds that non-Hispanic blacks report lower levels of alcohol use, hazardous use, and are at lower risk of alcohol use disorder than non-Hispanic whites. However, racial/ethnic patterns of hazardous alcohol use may differ among men who have sex with men (MSM). There is a gap in our knowledge about racial differences in patterns of alcohol use, hazardous drinking, and alcohol-related problems among MSM. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Emily Greene, Victoria Frye, Magdalena Cerdá, Danielle C. Ompad, Vijay Nandi, Don Hoover, Beryl Koblin Source Type: research

Sleep disturbance as a mediator of the relationship between smoking and major depressive disorder
Background: A compelling body of evidence links cigarette smoking with major depression, though the pathways explaining this association remain unclear. Recently, there is growing interest in the role of sleep problems in depression onset and persistence. Cigarette smoking has also been linked to sleep disruption. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Alice Grinberg, Carl Finkbiner, Farah Taha, Renee D. Goodwin Source Type: research

Antenatal prediction of postpartum depression with blood DNA methylation biomarkers
Background: Post partum depression (PPD) affects ~10–18% of women in the general population and results in serious consequences to both the mother and offspring. While depression risk is not predicted by serum levels of gonadal hormones in humans, exposure to estrogen appears to be a key factor in establishing PPD. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Jerry Guintivano, Michal Arad, Todd D. Gould, Jennifer L. Payne, Zachary Kaminsky Source Type: research

Low maternal thyroxine during early gestation and offspring schizophrenia in a national birth cohort
Background: Evidence from animal and human studies indicates that thyroid hormone deficiency during early gestation alters brain development. As schizophrenia is associated with prenatal brain insults and premorbid cognitive deficits, we tested the a priori hypothesis that serologically defined maternal thyroid deficiency during early gestation is associated with offspring schizophrenia. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: D. Gyllenberg, A. Sourander, H.-M. Surcel, S. Hinkka-Yli-Salomäki, A.S. Brown Source Type: research

An update from the Consortium on Lithium Genetics (ConLiGen): Phenomic and genomic studies
Background: Lithium remains a mainstay in the long-term treatment of bipolar disorder (BD). The individual response to lithium is variable. About 30% of patients treated with lithium have fewer illness episodes over time, while about 20% have no response. Data from pharmacogenetic studies of lithium are comparatively sparse, and these studies have generally employed small sample sizes and varying definitions of response. Genetic markers of lithium response would be valuable for treatment planning and could provide insights into the biological mechanism of lithium action. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: U. Heilbronner, L. Hou, M. Rietschel, F.J. McMahon, T.G. Schulze, The ConLiGen Consortium Source Type: research

Symptoms of PTSD and depression in suicidal rumination, contemplation, and plans in US soldiers
We examined the DSM-IV criteria for PTSD and depression and suicidality in active duty U.S. soldiers. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: R.K. Herrell, J.E. Wilk, C.W. Hoge Source Type: research

Examining age of onset of health risk behaviors as a mediator in the relationship between child maltreatment and psychosocial outcomes in middle adulthood
Background: Prior research has documented the wide-ranging and severe effects of child abuse and neglect across the lifespan. In particular, maltreatment has been linked to a number of health risk behaviors that are associated with long-lasting maladaptive psychosocial outcomes. However, it is not yet known whether the age of onset of these health risk behaviors acts as a conduit for later maladjustment for victims of abuse or neglect or increases risk. To fill this gap in knowledge, this study examines the mediating role of age of onset of five health risk behaviors – sexual intercourse, alcohol use, drug use, homel...
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: J.M. Horan, C.S. Widom Source Type: research

Interaction between stress and the Val66Met polymorphism in depression: A systematic review and meta-analysis
Background: Major depression is a disabling psychiatric illness with complex origins. Life stress (childhood adversity and recent stressful events) is a robust risk factor for depression. The relationship between life stress and Val66Met polymorphism in the Brain-derived neurotrophic factor [BDNF] gene has received much attention. The aim of the present study is to review and meta-analyze the results from published studies examining this interaction. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Georgina M. Hosang, Celia Shiles, Katherine E. Tansey, Peter McGuffin, Rudolf Uher Source Type: research

Translating personality psychology to help personalize preventive medicine for young-adult patients
The rising number of newly insured young adults brought on by healthcare reform will soon increase demands on primary-care physicians. Physicians will face more young-adult patients which presents an opportunity for more prevention-oriented care. In the current study, we evaluated whether brief observer reports of young adults' personality traits could predict which individuals would be at greater risk for poor health as they entered midlife. Following the Dunedin Study cohort of 1000 individuals, we show that very brief measures of young adults' personalities predicted their midlife physical health across multiple domains...
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Salomon Israel, Terrie E. Moffitt, Daniel W. Belsky, Robert J. Hancox, Richie Poulton, Brent Roberts, W. Murray Thomson, Avshalom Caspi Source Type: research

Identification and replication of a combined epigenetic and genetic biomarker predicting suicide and suicidal behaviors
Objective: Suicide is a major preventable public health problem. Reliable identification of individuals at increased suicide risk remains an unfulfilled priority for suicide prevention. The primary purpose of this study was to identify genes exhibiting epigenetic variation associated with suicide and suicidal behaviors. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Jerry Guintivano, Tori Brown, Marcus Jones, Brion S. Maher, William W. Eaton, Jennifer L. Payne, Holly C. Wilcox, Zachary A. Kaminsky Source Type: research

The effect of childhood abuse and neglect on clinical severity in mood disorders
Background: Mood disorders are common psychiatric disorders which affect 20% of the population during their lifetime. They are characterized by early onset, chronic nature, and severe consequences, including suicide attempts. Childhood adversity (CA) has been investigated as a major risk factor for the development of mood disorders, increasing the risk by 2-3-fold. However, significant knowledge gaps remain in the association between CA and mood disorders, especially regarding the impact of different types of CA on specific indicators of mood disorder severity. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: G.E. Kraus, E. Yung, N. Lebaron, X. Zhang, A. Iskric, J. Lober, N.C. Low Source Type: research

Racial disparities in diagnosis in patients presenting to emergency rooms: Persisting problem of misdiagnosis?
The objective of this study was to investigate racial differences in prevalence of schizophrenia and bipolar disorders among patients presenting to the emergency rooms in two states. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: William Lawson Source Type: research

Anxious and suicidal behaviors among relatives are associated with suicide attempts and hospitalizations in mood disorder subjects
Background: In individuals who suffer from mood disorders, suicidal behavior and psychiatric hospitalizations are used as indicators of illness severity. Both are considered highly detrimental to an individual's global functioning. Factors that increase the severity of a mood disorder are important to understand in order to develop interventions for prevention. Prior research has shown that having a relative with a psychiatric illness is a risk factor for developing the illness. However, the family members' specific disorders in addition to their history of suicidal behavior have not been examined with clinical severity ou...
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: N. LeBaron, X. Zhang, R. Herrell, S. Cho, A. Iskric, N.C. Low Source Type: research

Multimodal predictive modeling of individual treatment outcome in cocaine dependence with combined neuroimaging and behavioral predictors
Objective/hypothesis: Developing a personalized treatment plan for cocaine dependent patients remains a significant clinical challenge. Positron emission tomography (PET) has shown that the [11C]raclopride signal in the ventral striatum is significantly associated with treatment success in a positive reinforcement contingency management program at the group level. The present study investigates whether this signal can be used to predict treatment outcome at an individual level. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Sean X. Luo, Diana Martinez, Kenneth M. Carpenter, Mark Slifstein, Edward V. Nunes Source Type: research

Exploring Moffitt's developmental taxonomy of conduct disorder: An epidemiological study of childhood predictors and adult outcomes of ‘life course persistent’ and ‘adolescence limited’ conduct disorder
Background: Moffitt's (1993) developmental taxonomy of conduct disorder (CD) defines two CD subgroups: life-course persistent (LCP) and adolescence limited (AL). LCP CD is characterized by childhood onset with symptoms persisting into adulthood. AL CD is characterized by adolescent onset with symptoms desisting by adulthood. According to Moffitt, LCP CD stems from early childhood factors, whereas LCP CD stems from the adolescent environment. Moffitt also states that those with LCP CD have a lower quality of life in adulthood relative to those with AL CD. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: A.A. Moore, B. Mezuk Source Type: research

Sensitivity to criticism mediates the relationship between interpersonal problems and state and trait depressivity
Background: One of the primary challenges to the inclusion of a depressive personality disorder (DPD) diagnosis in the DSM is the inability to discriminate DPD from major depressive disorder (MDD) and dysthymia. Both MDD and dysthymia are accompanied by significant impairment in the social area of functioning, as is DPD. Barrett and Barber (2007) found that patients with both MDD and DPD reported more interpersonal distress than those with only MDD or MDD and dysthymia. One factor related to this impairment in the social area of functioning may be sensitivity to criticism, which can be understood as a component of perfecti...
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: A.P. Natoli, S.K. Huprich Source Type: research

Does executive functioning mediate the association between childhood maltreatment and adult psychopathy?
Background: Childhood maltreatment is an important public health problem linked to a range of negative outcomes, including poor neuropsychological functioning and psychopathy. Deficits in neuropsychological functions have been hypothesized to mediate the relationship between childhood maltreatment and adult psychopathic traits. Most recent research suggests that psychopathy is a multifaceted construct encompassing three to four facets (i.e. manipulative interpersonal style, callous and unemotional traits, impulsivity, and antisocial behavior), which may be differentially related to neuropsychological functioning. (Source: ...
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: V. Nikulina, C.S. Widom Source Type: research

When modesty goes too far: The Mediational role of positive dampening on depression
In emotion regulation research, responses to positive affect are as important as responses to negative affect. Individuals with or at risk for bipolar disorder may dampen positive affect in order to avoid succumbing to positive affect that is too extreme or to enforce the cognition that positive moods are not deserved (Parrott, 1998). This may allow them to maintain a depressogenic perspective of their world. Several studies have shown that depression is related to decreased responsivity to positive stimuli (Sloan, et al., 2002). (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Jared K. O’Garro-Moore, Danielle Zambrano, Lauren B. Alloy Source Type: research

Separation from parents during childhood and risk of schizophrenia and bipolar disorder: A population-based study in Denmark
Background: There is a growing body of research documenting associations between childhood parental loss, including parental separation and death, and psychotic disorders in adulthood. However, studies specifically investigating parental separation have yielded mixed results, and few have examined factors that might modify these associations. Our objective was to characterize associations of childhood parental separation with schizophrenia and bipolar disorder with respect to age, duration, and parental mental health. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: D. Paksarian, W.W. Eaton, P.B. Mortensen, K.R. Merikangas, C.B. Pedersen Source Type: research

Neural mechanisms of non-suicidal self-injury and suicidal behavior in adolescent girls
Very little is known about the neural mechanisms underlying non-suicidal self-injury (NSSI) in community dwelling adolescents, a potent and robust risk factor for adolescent suicidal behavior. To address this gap in our knowledge, we drew data from the baseline assessment of the Adolescent Development of Emotion and Personality Traits (ADEPT) project at Stony Brook University, an ongoing, 3-year multi-wave prospective study of 550 adolescent girls. All adolescent girls were assessed at baseline for NSSI, suicidal behavior, event-related potential (ERP) measures of neural mechanisms, and several well-established risk factor...
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Greg Perlman, Brady Nelson, Greg Hajcak Proudfit, Daniel Klein, Roman Kotov Source Type: research

Association of depression and obesity with hypertension, diabetes and heart disease
This study examines whether persons with obesity who also have depression are more likely to have heart disease, hypertension or diabetes than are persons with obesity alone. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Pratt LA, Brody DJ Source Type: research

Emotion processing deficits and emotion-related disruption of working memory in psychotic disorders
Background: Deficits in emotional processing and working memory (WM) dysfunction have both been found to show prominent impairments in patients with schizophrenia, and their biological correlates have been recommended as candidates for biomarker development by Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) initiative. These socio-cognitive deficits have been shown to be key predictors of quality of life and functioning in schizophrenia. However, it is unclear whether these deficits and imaging biomarkers are indicative specifically of schizophrenia, or generally of psychosis, and ...
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: A. Sabharwal, P. Mukherjee, A. Szekely, R. Kotov, A. Mohanty Source Type: research

Impact of preeclampsia on birth outcomes and long-term neurobehavioral dysfunction
Background: Preeclampsia is a common ailment unique to pregnancy characterized by hypertension and proteinuria. The etiology of this heterogeneous disorder is little understood, resulting in great difficulty in designing effective intervention strategies for both mother and baby. Additionally, the scope and severity of the impact of preeclampsia on birth outcomes and infant development are similarly elusive. The current study aims to investigate the impact of maternal preeclampsia on preterm labor, APGAR scores, low birth weight, and early neurobehavioral outcomes, and explores the potential use of these measures as early ...
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: J. Salzbank, J. Finik, Y. Nomura Source Type: research

Cortisol and alpha amylase response patterns among young african american women with high rates of violence exposure
Background: Girls from low-income urban communities are at disproportionate risk for violence exposure, which can have adverse consequences for physical and mental health. Dysregulation of stress response systems, including the hypothalamic-pituitary-adrenal (HPA) axis and sympathetic nervous system (SNS), may help to explain negative outcomes. The current study examined patterns of salivary cortisol, reflecting HPA activity, and α-amylase, marking SNS activity, in response to a laboratory stressor with a sample of young African American women with high rates of violence exposure. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: E.A. Goodman, S. Samuelson, D.A. Granger, H.W. Wilson Source Type: research

Perinatal complications predict subjective and objective aging indicators by midlife
Background: The model of the developmental origins of health and disease suggests that impaired growth in utero may permanently change the body's function and metabolism, leading to accelerated aging. Adverse conditions during prenatal development, resulting in low birth-weight or prematurity, predict increased risk of early mortality. Evidence of perinatal programming of adult mortality raises the question of what mechanisms embed this long-term effect. We tested the hypothesis that perinatal complications are associated with biomarkers of accelerated aging already at midlife, before onset of aging-related diseases. (Sour...
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Idan Shalev, Avshalom Caspi, Terrie E. Moffitt Source Type: research

Does the age of the child affect drinking in the mothers?
Background: Previous studies have indicated that women living with children experience more stress, alcohol use and depression. We hypothesized that due to differences in stress of parenting children of different age groups; mothers living with children 10years of age or younger would drink more, have drinking problems and have more depression compared to women living with children older than 10years. (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: Sherpa M. L, Lasopa S. O, Vaddiparti K, Striley C. W, Cottler L. B Source Type: research

Disentangling the relationship between depression, depressive personality, vulnerable narcissism, and malignant self-regard
Background: Findings are robust that depression is associated with vulnerable narcissism (VN) and depressive personality disorder (Tritt, Ryder, Ring, & Pincus, 2010; Huprich, Luchner, Roberts, & Pouliot, 2012); however, there is no specification of what aspects of VN are most strongly related to DPD and if all VN dimensions are equally associated with DPD. Furthermore, past findings have demonstrated that malignant self-regard (MSR) is a superordinate construct that accounts for the comorbid pattern of depression, vulnerable narcissism, and depressive personality (Huprich & Nelson, in press). (Source: Comprehensive Psychiatry)
Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Authors: A.L. Smith, S.K. Huprich Source Type: research

Masthead
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Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Source Type: research

Editorial Board
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Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Source Type: research

Information for Contributors
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Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Source Type: research

Table of Contents
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Source: Comprehensive Psychiatry - November 1, 2014 Category: Psychiatry Source Type: research