Neurotransmitter-affecting medicines used in pregnancy not linked to autism risk in offspring
Maternal use of medicines targeting neurotransmitter systems is unlikely to directly affect the risk of autism spectrum disorder in offspring, the authors of a study published in JAMA Psychiatry have concluded. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - December 10, 2018 Category: Drugs & Pharmacology Source Type: research
First-year statin discontinuation and non-adherence common in older adults
A substantial proportion of older people who begin taking statins do not take them as intended, according to an Australian study published in the British Journal of Clinical Pharmacology. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - December 7, 2018 Category: Drugs & Pharmacology Source Type: research
Pathophysiology and management of heart failure
Ensuring patients are optimised on maximum tolerated doses of medicines in heart failure with reduced ejection fraction is essential in minimising the burden of the condition. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - December 6, 2018 Category: Drugs & Pharmacology Source Type: research
ACEIs linked to increased risk of lung cancer
An observational study of almost one million people suggests a link between angiotensin converting enzyme inhibitors and an increased risk of lung cancer. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - December 5, 2018 Category: Drugs & Pharmacology Source Type: research
Cannabinoids have limited impact on MS symptoms
Following a systematic review and meta-analysis researchers have concluded that cannabinoids have limited therapeutic effect on symptoms of multiple sclerosis (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - December 3, 2018 Category: Drugs & Pharmacology Source Type: research
Intravenous fluid management
An introduction to fluid management for adults in hospitals, covering replacement during resuscitation, malnourished patients and following large electrolyte losses. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - November 30, 2018 Category: Drugs & Pharmacology Source Type: research
Patients are being underdosed: we need new guidance on small-volume drug infusions
Too many patients are not receiving their full prescribed dose with small-volume drug infusions, but hospital pharmacists can act to ensure patient safety. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - November 30, 2018 Category: Drugs & Pharmacology Source Type: research
Raised urate levels more strongly linked to genetics than diet, study finds
Diet contributes much less towards the development of high serum urate levels than genetic factors, study results reported in The BMJ suggest. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - November 30, 2018 Category: Drugs & Pharmacology Source Type: research
Triple therapy cuts exacerbations in COPD regardless of baseline reversibility
Triple therapy reduces the number of moderate-to-severe exacerbations in people with chronic obstructive pulmonary disease, a study presented at the CHEST annual meeting has shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - November 28, 2018 Category: Drugs & Pharmacology Source Type: research
Weight loss drug reduces risk of diabetes in overweight and obese people
Taking lorcaserin and making lifestyle changes can help prevent diabetes in people who are overweight or obese, study findings indicate. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - November 26, 2018 Category: Drugs & Pharmacology Source Type: research
Rolling out emergency treatment boxes for bacterial endophthalmitis
Bacterial endophthalmitis is a sight-threatening infection of the eye, which may occur after penetrating injuries and ocular procedures. Bacterial load in the eye can double within 30 minutes. For this reason, European guidelines recommend delivery of endophthalmitis treatment within one hour of presentation (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - November 26, 2018 Category: Drugs & Pharmacology Source Type: research
New antibiotic effective against multi-drug resistant Gram-negative UTI
A new antibiotic designed to overcome multi-drug resistance is at least as effective as the current standard of care in complicated urinary tract infection, according to trial results published in The Lancet Infectious Diseases. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - November 23, 2018 Category: Drugs & Pharmacology Source Type: research
Anticoagulation: hospital and GP-based pharmacists working together
The pharmacist-led direct oral anticoagulation (DOAC) clinic at Northwick Park Hospital in Harrow, north west London, was set up in April 2017 and sees patients from Brent and Harrow clinical commissioning groups. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - November 21, 2018 Category: Drugs & Pharmacology Source Type: research
Low-dose aspirin cuts ovarian cancer risk
Use of low-dose aspirin is associated with a reduced risk of ovarian cancer, results from a cohort study show. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - November 21, 2018 Category: Drugs & Pharmacology Source Type: research
Durvalumab increases overall survival in stage III non-small-cell lung cancer
The immune checkpoint inhibitor durvalumab significantly improves survival in people with stage III non-small-cell lung cancer, interim trial results published in The New England Journal of Medicine have shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - November 19, 2018 Category: Drugs & Pharmacology Source Type: research
