Monthly vitamin D dosing has no significant effect on bone mineral density
Monthly dosing of vitamin D3 supplements in older adults does not increase bone mineral density, the results of a recent study show. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - February 13, 2019 Category: Drugs & Pharmacology Source Type: research
Patient-centred clinic improves outcomes after myocardial infarction
A post-myocardial infarction medicines optimisation clinic, led primarily by a pharmacist with support from a cardiologist, has resulted in improved medicines adherence and guideline concordance, study results published in Open Heart show. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - February 11, 2019 Category: Drugs & Pharmacology Source Type: research
Responding to disruptions in the pharmaceutical supply chain
Economic, manufacturing and regulatory factors can affect drug shortages and supply chain disruption. By using a mixed-methods approach involving an online survey, semi-structured interviews and three targeted focus groups aimed at acute care hospitals in England, Wales, Northern Ireland and Ireland, this study determined that over half of the responding acute care hospitals did not have 76–100% of medicine lines fulfilled within 8 weeks of a disruption in the supply chain. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - February 6, 2019 Category: Drugs & Pharmacology Source Type: research
Prevention of venous thromboembolism in hospitalised patients
Pharmacists should note the National Institute for Health and Care Excellence ’s updated guidance on use of pharmacological thromboprophylaxis in a range of hospitalised patient groups. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - February 5, 2019 Category: Drugs & Pharmacology Source Type: research
Uncertainty on long-term efficacy of osteoarthritis medicines
There is a lack of evidence that medicines for osteoarthritis are effective in the long term, according to a review in the Journal of the American Medical Association. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - February 5, 2019 Category: Drugs & Pharmacology Source Type: research
UK asthma mortality is too high, but pharmacy can help
Since many deaths from asthma could be prevented with the correct treatment, pharmacists should have a greater role in ensuring patients receive the right medicines and referring patients who do not have well-controlled asthma. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - February 1, 2019 Category: Drugs & Pharmacology Source Type: research
Sulfonylureas and basal insulin linked to elevated cardiovascular risk
Sulfonylureas and basal insulin confer an increased risk of cardiovascular events compared with newer second-line medicines for type 2 diabetes mellitus, research has found. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - February 1, 2019 Category: Drugs & Pharmacology Source Type: research
Statins and metformin could be used to treat serious mental illness
Existing medicines for physical conditions such as diabetes and hypertension could be used to treat serious mental illness, concluded the authors of a recent study in JAMA Psychiatry. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - January 30, 2019 Category: Drugs & Pharmacology Source Type: research
Cannabinoids could help manage spasticity in motor neurone disease
An oral spray containing cannabinoids is effective at reducing spasticity symptoms in motor neurone disease, study results have shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - January 28, 2019 Category: Drugs & Pharmacology Source Type: research
Palbociclib slows tumour growth in early breast cancer
Adding the CDK4/6 inhibitor palbociclib to hormone therapy can slow or stop tumour growth in women with early breast cancer, a study in the Journal of Clinical Oncology has shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - January 25, 2019 Category: Drugs & Pharmacology Source Type: research
Working with schools to help young people and their families stop smoking
Smoking remains the single biggest preventable cause of ill health and premature death in Wales[1], and a significant cause of health inequality. Pembroke Dock, a town in south-west Wales, has a population of around 10,000 people. ... (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - January 24, 2019 Category: Drugs & Pharmacology Source Type: research
BMI is an effective indicator of cardiometabolic health, researchers say
A study of adolescents supports the use of body mass index measurement as a helpful tool for detecting the metabolic and cardiovascular effects of obesity. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - January 23, 2019 Category: Drugs & Pharmacology Source Type: research
Fluoxetine does not assist recovery following stroke, research suggests
Daily fluoxetine in patients who have had a stroke does not improve functional outcomes at six months, results of a randomised trial published in The Lancet have shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - January 21, 2019 Category: Drugs & Pharmacology Source Type: research
Increased intensity plus adherence maximises statin benefits
High adherence to intensive lipid-lowering therapy provides the greatest risk reduction for cardiovascular events, a study in JAMA Network Open has shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - January 16, 2019 Category: Drugs & Pharmacology Source Type: research
First-line immunotherapy does not improve survival in metastatic lung cancer
Single or combination first-line immunotherapy does not significantly extend survival compared with chemotherapy in metastatic non small-cell lung carcinoma, trial results have shown. (Source: Clinical Pharmacist)
Source: Clinical Pharmacist - January 14, 2019 Category: Drugs & Pharmacology Source Type: research
