Intracardiac Echinococcal Cyst Causing Biventricular Cavity Obliteration [Images and Case Reports in Heart Failure]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 16, 2018 Category: Cardiology Authors: Warraich, H. J., Rymer, J. A., Schroder, J. N., Kim, H. W., Leithe, M. E., Harrison, J. K. Tags: Computerized Tomography (CT), Magnetic Resonance Imaging (MRI), Cardiovascular Surgery Images and Case Reports in Heart Failure Source Type: research
From Molecules to Markets: Broadening the Focus of Cardiovascular Innovation [Editorial]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 16, 2018 Category: Cardiology Authors: Colaco, N. A., Kazi, D. S. Tags: Heart Failure, Health Services, Quality and Outcomes Editorial Source Type: research
Adoption of Sacubitril/Valsartan for the Management of Patients With Heart Failure [Original Articles]
Conclusions:
Adoption of sacubitril/valsartan after Food and Drug Administration approval has been slow and may be associated with the high cost. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 16, 2018 Category: Cardiology Authors: Sangaralingham, L. R., Sangaralingham, S. J., Shah, N. D., Yao, X., Dunlay, S. M. Tags: Heart Failure, Health Services Original Articles Source Type: research
Serum Transthyretin: Predictor of Amyloidosis Outcomes? [Editorial]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 15, 2018 Category: Cardiology Authors: Nativi-Nicolau, J. Tags: Cardiomyopathy Editorial Source Type: research
Immunosuppressive Therapy Improves Both Short- and Long-Term Prognosis in Patients With Virus-Negative Nonfulminant Inflammatory Cardiomyopathy [Original Articles]
Conclusions:
To conclude, this study suggests that immunosuppressive therapy in infl-CMP patients results in an improved heart transplantation–free survival as compared with standard heart failure therapy alone, underscoring the urgent need for a large prospective multicenter trial. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 15, 2018 Category: Cardiology Authors: Merken, J., Hazebroek, M., Van Paassen, P., Verdonschot, J., Van Empel, V., Knackstedt, C., Abdul Hamid, M., Seiler, M., Kolb, J., Hoermann, P., Ensinger, C., Brunner-La Rocca, H.-P., Poelzl, G., Heymans, S. Tags: Cardiomyopathy Original Articles Source Type: research
Load-Independent Systolic and Diastolic Right Ventricular Function in Heart Failure With Preserved Ejection Fraction as Assessed by Resting and Handgrip Exercise Pressure-Volume Loops [Original Articles]
Conclusions:
In compensated stages of the HFpEF syndrome, systolic RV function is preserved, but diastolic abnormalities with intrinsic RV stiffness and prolonged RV relaxation are already present. Impaired diastolic RV reserve contributes to a blunted increase in cardiac output during exertion. Because impairments in diastolic function seem to be a biventricular phenomenon, RV diastolic dysfunction warrants further consideration when characterizing HFpEF patients.
Clinical Trial Registration:
https://www.clinicaltrials.gov. Unique identifier: NCT02459626. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 15, 2018 Category: Cardiology Authors: Rommel, K.-P., von Roeder, M., Oberueck, C., Latuscynski, K., Besler, C., Blazek, S., Stiermaier, T., Fengler, K., Adams, V., Sandri, M., Linke, A., Schuler, G., Thiele, H., Lurz, P. Tags: Heart Failure Original Articles Source Type: research
Use of Serum Transthyretin as a Prognostic Indicator and Predictor of Outcome in Cardiac Amyloid Disease Associated With Wild-Type Transthyretin [Original Articles]
Conclusions:
In this series of biopsy-proven ATTRwt, lower baseline serum TTR concentration was associated with shorter survival as an independent predictor of outcome. Longitudinal analysis demonstrated that decreasing TTR corresponded to worsening cardiac function. These data suggest that TTR may be a useful prognostic marker and predictor of outcome in ATTRwt. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 15, 2018 Category: Cardiology Authors: Hanson, J. L. S., Arvanitis, M., Koch, C. M., Berk, J. L., Ruberg, F. L., Prokaeva, T., Connors, L. H. Tags: Biomarkers, Aging, Risk Factors, Cardiomyopathy, Heart Failure Original Articles Source Type: research
Plasma MicroRNA Clusters in Human Left Ventricular Remodeling: A Biomarker and Discovery Platform [Editorial]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 9, 2018 Category: Cardiology Authors: Padmanabhan, A., Haldar, S. M. Tags: Biomarkers Editorial Source Type: research
MicroRNAs Associated With Reverse Left Ventricular Remodeling in Humans Identify Pathways of Heart Failure Progression [Original Articles]
Conclusions:
Plasma miRNAs associated with LV reverse remodeling in humans are dysregulated in animal HF and target clusters of genes involved in mechanisms implicated in HF. A translational approach integrating human HF, bioinformatics, and model systems may uncover novel pathways involved in HF.
CLINICAL TRIAL REGISTRATION:
URL: https://www.clinicaltrials.gov. Unique identifier: NCT00351390 (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - February 9, 2018 Category: Cardiology Authors: Shah, R., Ziegler, O., Yeri, A., Liu, X., Murthy, V., Rabideau, D., Xiao, C. Y., Hanspers, K., Belcher, A., Tackett, M., Rosenzweig, A., Pico, A. R., Januzzi, J. L., Das, S. Tags: Heart Failure Original Articles Source Type: research
Definition of Iron Deficiency Based on the Gold Standard of Bone Marrow Iron Staining in Heart Failure Patients [Original Articles]
Conclusions
A TSAT ≤19.8% or a serum iron ≤13 µmol/L shows the best performance in selecting patients with ID and identifies HF patients at the highest risk of death. Our findings validate the currently used TSAT cutoff of <20% for the identification of ID in HF patients, but question the diagnostic value of ferritin. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - January 30, 2018 Category: Cardiology Authors: Grote Beverborg, N., Klip, I. T., Meijers, W. C., Voors, A. A., Vegter, E. L., van der Wal, H. H., Swinkels, D. W., van Pelt, J., Mulder, A. B., Bulstra, S. K., Vellenga, E., Mariani, M. A., de Boer, R. A., van Veldhuisen, D. J., van der Meer, P. Tags: Clinical Studies, Heart Failure, Diagnostic Testing Original Articles Source Type: research
Percutaneous Occlusion of Patent Ductus Arteriosus for an Elderly Patient With Refractory Congestive Heart Failure [Images and Case Reports in Heart Failure]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - January 24, 2018 Category: Cardiology Authors: Shoji, S., Kanazawa, H., Yanagisawa, R., Tanaka, M., Fukuoka, R., Akita, K., Kimura, M., Arai, T., Kawakami, T., Hayashida, K., Yuasa, S., Tsuruta, H., Itabashi, Y., Murata, M., Nishiyama, T., Kohno, T., Maekawa, Y., Fukuda, K. Tags: Congenital Heart Disease, Heart Failure Images and Case Reports in Heart Failure Source Type: research
Hyporesponsiveness to Darbepoetin Alfa in Patients With Heart Failure and Anemia in the RED-HF Study (Reduction of Events by Darbepoetin Alfa in Heart Failure): Clinical and Prognostic Associations [Short Communications]
Conclusions:
A poor response to darbepoetin alfa was associated with worse outcomes in heart failure patients with anemia. Patients with a poor response were difficult to identify using clinical and biochemical biomarkers.
Clinical Trial Registration:
URL: https://www.clinicaltrials.gov. Unique identifier: NCT00358215. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - January 24, 2018 Category: Cardiology Authors: van der Meer, P., Grote Beverborg, N., Pfeffer, M. A., Olson, K., Anand, I. S., Westenbrink, B. D., McMurray, J. J. V., Swedberg, K., Young, J. B., Solomon, S. D., van Veldhuisen, D. J. Tags: Clinical Studies, Heart Failure, Mortality/Survival Short Communications Source Type: research
Editorial Board [Editorial Board]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - January 16, 2018 Category: Cardiology Tags: Editorial Board Source Type: research
Novel Wearable Seismocardiography and Machine Learning Algorithms Can Assess Clinical Status of Heart Failure Patients [Original Articles]
Conclusions
Wearable technologies recording cardiac function and machine learning algorithms can assess compensated and decompensated HF states by analyzing cardiac response to submaximal exercise. These techniques can be tested in the future to track the clinical status of outpatients with HF and their response to pharmacological interventions. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - January 12, 2018 Category: Cardiology Authors: Inan, O. T., Baran Pouyan, M., Javaid, A. Q., Dowling, S., Etemadi, M., Dorier, A., Heller, J. A., Bicen, A. O., Roy, S., De Marco, T., Klein, L. Tags: Biomarkers, Information Technology, Physiology, Heart Failure Original Articles Source Type: research
Heart Failure in Pregnant Women: A Concern Across the Pregnancy Continuum [Original Articles]
Conclusions
HF is associated with increased risk of maternal mortality and morbidities. During hospitalization, high-risk mothers need to be identified and surveillance programs developed before discharge. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - January 12, 2018 Category: Cardiology Authors: Mogos, M. F., Piano, M. R., McFarlin, B. L., Salemi, J. L., Liese, K. L., Briller, J. E. Tags: Cardiomyopathy, Heart Failure Original Articles Source Type: research
