Impact of Socioeconomic Status on Patients Supported With a Left Ventricular Assist Device: An Analysis of the UNOS Database (United Network for Organ Sharing) [Original Articles]
Conclusions—
Freedom from waitlist death or delisting was not affected by SES. Patients with a higher SES had an increased unadjusted risk of waitlist mortality during LVAD support, which was mitigated by adjusting for increased comorbid conditions. Low SES was associated with worse post-HT outcomes. Further study is needed to confirm and understand a differential effect of SES on post-transplant outcomes that was not seen during LVAD support before HT. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - October 6, 2016 Category: Cardiology Authors: Clerkin, K. J., Garan, A. R., Wayda, B., Givens, R. C., Yuzefpolskaya, M., Nakagawa, S., Takeda, K., Takayama, H., Naka, Y., Mancini, D. M., Colombo, P. C., Topkara, V. K. Tags: Heart Failure, Ethics and Policy, Mortality/Survival Original Articles Source Type: research
Palliative Care Throughout the Journey of Life With a Left Ventricular Assist Device [Editorial]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - October 5, 2016 Category: Cardiology Authors: Teuteberg, W., Maurer, M. Tags: Heart Failure Editorial Source Type: research
Dying With a Left Ventricular Assist Device as Destination Therapy [Original Articles]
Conclusions—
In contrast to the general heart failure population, most patients with DT-LVAD die in the hospital and few use hospice. Further work is needed to understand these differences and to determine whether patients with DT-LVAD are receiving optimal end-of-life care. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - October 5, 2016 Category: Cardiology Authors: Dunlay, S. M., Strand, J. J., Wordingham, S. E., Stulak, J. M., Luckhardt, A. J., Swetz, K. M. Tags: Heart Failure, Quality and Outcomes Original Articles Source Type: research
Dilemmas With Race and Heart Failure Treatment [Development of Therapeutics for Heart Failure: Expedited Commentary]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - October 4, 2016 Category: Cardiology Authors: Butler, J., Konstam, M. A. Tags: Heart Failure Development of Therapeutics for Heart Failure: Expedited Commentary Source Type: research
Transforming Drug Development in Heart Failure: Navigating the Regulatory Crossroads [Development of Therapeutics for Heart Failure: Expedited Commentary]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - October 4, 2016 Category: Cardiology Authors: Vaduganathan, M., Butler, J., Gheorghiade, M. Tags: Clinical Studies, Heart Failure, Treatment Development of Therapeutics for Heart Failure: Expedited Commentary Source Type: research
Reversible Right Heart Failure in Scurvy Rediscovery of an Old Observation [Images and Case Reports in Heart Failure]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - September 27, 2016 Category: Cardiology Authors: Abbas, F., Ha, L. D., Sterns, R., von Doenhoff, L. Tags: Diet and Nutrition, Cardiomyopathy, Heart Failure, Echocardiography, Imaging Images and Case Reports in Heart Failure Source Type: research
Risk Factors for Incident Hospitalized Heart Failure With Preserved Versus Reduced Ejection Fraction in a Multiracial Cohort of Postmenopausal Women [Original Articles]
Conclusions—
In this multiracial cohort of postmenopausal women, obesity stands out as a significant risk factor for HFpEF, with the strongest association in African American women.
Clinical Trial Registration—
URL: http://www.clinicaltrials.gov. Unique identifier: NCT00000611. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - September 27, 2016 Category: Cardiology Authors: Eaton, C. B., Pettinger, M., Rossouw, J., Martin, L. W., Foraker, R., Quddus, A., Liu, S., Wampler, N. S., Hank Wu, W.-C., Manson, J. E., Margolis, K., Johnson, K. C., Allison, M., Corbie-Smith, G., Rosamond, W., Breathett, K., Klein, L. Tags: Race and Ethnicity, Heart Failure Original Articles Source Type: research
Changes in Left Ventricular Ejection Fraction Predict Survival and Hospitalization in Heart Failure With Reduced Ejection Fraction [Original Article]
Conclusions—
Serial evaluation for LVEF change predicts both survival and heart failure hospitalization and provides a dynamic/real-time measure of prognosis in heart failure with reduced LVEF.
Clinical Trial Registration—
URL: http://www.clinicaltrials.gov. Unique identifier: NCT00000560. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - September 20, 2016 Category: Cardiology Authors: Breathett, K., Allen, L. A., Udelson, J., Davis, G., Bristow, M. Tags: Heart Failure, Mortality/Survival, Quality and Outcomes Original Article Source Type: research
Acute Lymphocytic Myocarditis With Anti-PD-1 Antibody Nivolumab [Images and Case Reports in Heart Failure]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - September 19, 2016 Category: Cardiology Authors: Tadokoro, T., Keshino, E., Makiyama, A., Sasaguri, T., Ohshima, K., Katano, H., Mohri, M. Tags: Heart Failure, Inflammatory Heart Disease Images and Case Reports in Heart Failure Source Type: research
Site Selection and Performance in Clinical Trials: The Need for Better Understanding [Editorials]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - September 12, 2016 Category: Cardiology Authors: McMurray, J. J. V. Tags: Clinical Studies, Heart Failure, Quality and Outcomes Editorials Source Type: research
Ultrasonic Assessment of Myocardial Microstructure in Hypertrophic Cardiomyopathy Sarcomere Mutation Carriers With and Without Left Ventricular Hypertrophy [Forum for Early Career Clinical Investigation]
Conclusions—
Our findings suggest that the SIC could serve as a noninvasive quantitative tool for assessing altered myocardial tissue characteristics in patients with genetic mutations associated with HCM. Further studies are needed to determine whether the SIC could be used to identify subclinical changes in patients at risk for HCM and to evaluate the effects of interventions. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - September 12, 2016 Category: Cardiology Authors: Hiremath, P., Lawler, P. R., Ho, J. E., Correia, A. W., Abbasi, S. A., Kwong, R. Y., Jerosch-Herold, M., Ho, C. Y., Cheng, S. Tags: Clinical Studies, Cardiomyopathy, Echocardiography, Imaging, Ultrasound Forum for Early Career Clinical Investigation Source Type: research
Influence of Clinical Trial Site Enrollment on Patient Characteristics, Protocol Completion, and End Points: Insights From the ASCEND-HF Trial (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure) [Original Article]
Conclusions—
In this large, acute heart failure trial, site enrollment correlated with protocol completion and was independently associated with trial end points. Individual and regional site performance present challenges to be considered in design of future acute heart failure trials.
Clinical Trial Registration—
URL: http://www.clinicaltrials.gov. Unique identifier: NCT00475852. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - September 12, 2016 Category: Cardiology Authors: Greene, S. J., Hernandez, A. F., Sun, J.-L., Metra, M., Butler, J., Ambrosy, A. P., Ezekowitz, J. A., Starling, R. C., Teerlink, J. R., Schulte, P. J., Voors, A. A., Armstrong, P. W., OConnor, C. M., Mentz, R. J. Tags: Clinical Studies, Heart Failure, Quality and Outcomes Original Article Source Type: research
Recovery of Serum Cholesterol Predicts Survival After Left Ventricular Assist Device Implantation [Original Article]
Conclusions—
Initiation of continuous-flow LVAD support was associated with significant recovery of all 4 lipid variables. Patients with a greater increase in total cholesterol by 3 months post implantation had superior survival during LVAD support. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - September 12, 2016 Category: Cardiology Authors: Vest, A. R., Kennel, P. J., Maldonado, D., Young, J. B., Mountis, M. M., Naka, Y., Colombo, P. C., Mancini, D. M., Starling, R. C., Schulze, P. C. Tags: Clinical Studies, Lipids and Cholesterol, Heart Failure Original Article Source Type: research
V122I TTR Cardiac Amyloidosis in Patients of African Descent: Recognizing a Missed Disease or the Dog That Didnt Bark? [Editorials]
(Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - September 11, 2016 Category: Cardiology Authors: Alexander, K. M., Falk, R. H. Tags: Race and Ethnicity, Cardiomyopathy, Heart Failure Editorials Source Type: research
Afro-Caribbean Heart Failure in the United Kingdom: Cause, Outcomes, and ATTR V122I Cardiac Amyloidosis [Original Article]
Conclusions—
In London, the cause of heart failure varies depending on ethnicity and affects age of presentation and outcomes. In Afro-Caribbean patients, ATTR V122I is an underappreciated cause of heart failure, and cardiomyopathy is often misattributed to hypertension. As promising TTR therapies are in development, increased awareness and proactive detection are needed. (Source: Circulation: Heart Failure)
Source: Circulation: Heart Failure - September 11, 2016 Category: Cardiology Authors: Dungu, J. N., Papadopoulou, S. A., Wykes, K., Mahmood, I., Marshall, J., Valencia, O., Fontana, M., Whelan, C. J., Gillmore, J. D., Hawkins, P. N., Anderson, L. J. Tags: Race and Ethnicity, Cardiomyopathy, Heart Failure, Echocardiography, Mortality/Survival Original Article Source Type: research
