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Response by Zghaib et al to Letter Regarding Article, "Standard Ablation Versus Magnetic Resonance Imaging-Guided Ablation in the Treatment of Ventricular Tachycardia" [Response to Letter to the Editor]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2018 Category: Cardiology Authors: Zghaib, T., Ipek, E. G., Hansford, R., Ashikaga, H., Berger, R. D., Marine, J. E., Spragg, D. D., Tandri, H., Zimmerman, S. L., Halperin, H., Brancato, S., Calkins, H., Henrikson, C., Nazarian, S. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Magnetic Resonance Imaging (MRI) Response to Letter to the Editor Source Type: research

Fast and the Furious: Electrogram Drift: Dynamic Analysis of Acquired Electrograms to Optimize Discrimination of Ventricular Tachycardia Substrate [Editorial]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2018 Category: Cardiology Authors: Killu, A. M., Kella, D., Kapa, S. Tags: Arrhythmias, Electrophysiology Editorial Source Type: research

Recurrence Post-Atrial Fibrillation Ablation: Think Outside the Pulmonary Veins [Editorial]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2018 Category: Cardiology Authors: Yamaguchi, T., Marrouche, N. F. Tags: Electrophysiology, Atrial Fibrillation Editorial Source Type: research

Creation of Continuous and Transmural Radiofrequency Lesions [Editorial]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2018 Category: Cardiology Authors: Nakagawa, H. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Atrial Fibrillation Editorial Source Type: research

Letter by Penela et al Regarding Article, "Standard Ablation Versus Magnetic Resonance Imaging-Guided Ablation in the Treatment of Ventricular Tachycardia" [Letter to the Editor]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2018 Category: Cardiology Authors: Penela, D., Andreu, D., Berruezo, A. Tags: Arrhythmias Letter to the Editor Source Type: research

Understanding Mechanisms of Cardiac Resynchronization Therapy Response to Improve Patient Selection and Outcomes [Editorial]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2018 Category: Cardiology Authors: Waks, J. W., Perez-Alday, E. A., Tereshchenko, L. G. Tags: Electrophysiology Editorial Source Type: research

Mortality and Sudden Cardiac Death Risk Stratification Using the Noninvasive Combination of Wide QRS Duration and Late Gadolinium Enhancement in Idiopathic Dilated Cardiomyopathy [Original Articles]
Conclusions: The combination of LGE and wQRS provides additional prognostic stratification compared with LGE status alone and might improve the appropriate use of implantable cardioverter defibrillator therapy in patients with dilated cardiomyopathy. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2018 Category: Cardiology Authors: Marume, K., Noguchi, T., Tateishi, E., Morita, Y., Kamakura, T., Ishibashi, K., Noda, T., Miura, H., Nishimura, K., Nakai, M., Yamada, N., Tsujita, K., Anzai, T., Kusano, K., Ogawa, H., Yasuda, S. Tags: Arrhythmias, Sudden Cardiac Death, Heart Failure Original Articles Source Type: research

Lesion Index-Guided Ablation Facilitates Continuous, Transmural, and Durable Lesions in a Porcine Recovery Model [Original Articles]
Conclusions: In this model of chronic atrial ablation, delivery of uninterrupted transmural linear lesions may be facilitated by using LSI to guide catheter movement. When LSI between adjacent lesions is ≤1.5 mm, no gaps in atrial linear lesions should be expected. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2018 Category: Cardiology Authors: Whitaker, J., Fish, J., Harrison, J., Chubb, H., Williams, S. E., Fastl, T., Corrado, C., Van Zaen, J., Gibbs, J., ONeill, L., Mukherjee, R., Rittey, D., Thorsten, J., Donskoy, E., Sohal, M., Rajani, R., Niederer, S., Wright, M., ONeill, M. D. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator, Electrophysiology, Atrial Fibrillation Original Articles Source Type: research

Left Ventricular Isovolumetric Relaxation Time Is Prolonged in Fetal Long-QT Syndrome [Original Articles]
Conclusions: The LVIRT is prolonged in LQTS fetuses. Findings of a prolonged N-LVIRT and sinus bradycardia can improve the prenatal detection of fetal LQTS. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2018 Category: Cardiology Authors: Clur, S.-A. B., Vink, A. S., Etheridge, S. P., Robles de Medina, P. G., Rydberg, A., Ackerman, M. J., Wilde, A. A., Blom, N. A., Benson, D. W., Herberg, U., Donofrio, M. T., Cuneo, B. F. Tags: Arrhythmias, Ion Channels/Membrane Transport, Pediatrics, Echocardiography, Ultrasound Original Articles Source Type: research

Recurrent Atrial Fibrillation After Initial Long-Term Ablation Success: Electrophysiological Findings and Outcomes of Repeat Ablation Procedures [Original Articles]
Conclusions: PV reconnection is the most common electrophysiological finding in patients with atrial fibrillation recurrence after long-term success, but with lower rates than what had been reported for early recurrences. In our experience, repeat ablations in this setting involve complex ablation approaches to reisolate the PVs and modify the atrial substrate and are associated with good success rates. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2018 Category: Cardiology Authors: Shah, S., Barakat, A. F., Saliba, W. I., Abdur Rehman, K., Tarakji, K. G., Rickard, J., Bassiouny, M., Baranowski, B., Tchou, P., Bhargava, M., Chung, M., Dresing, T., Callahan, T., Cantillon, D., Kanj, M., Lindsay, B. D., Wazni, O. M., Hussein, A. A. Tags: Arrhythmias, Electrophysiology, Atrial Fibrillation Original Articles Source Type: research

New Substrate-Guided Method of Predicting Slow Conducting Isthmuses of Ventricular Tachycardia: Preliminary Analysis to the Combined Use of Voltage Limit Adjustment and Fast-Fourier Transform Analysis [Original Articles]
Conclusions: Combined use of VLA and fast-Fourier transform analysis may be a useful method to detect VT isthmuses. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2018 Category: Cardiology Authors: Kuroki, K., Nogami, A., Igarashi, M., Masuda, K., Kowase, S., Kurosaki, K., Komatsu, Y., Naruse, Y., Machino, T., Yamasaki, H., Xu, D., Murakoshi, N., Sekiguchi, Y., Aonuma, K. Tags: Catheter Ablation and Implantable Cardioverter-Defibrillator Original Articles Source Type: research

Health Care Costs After Cardiac Arrest in the United States [Original Articles]
Conclusions: In the period between 2003 and 2012, postcardiac arrest hospitalizations resulted in a steady rise in associated health care cost, likely related to increased length of stay, medical procedures, and systems of care. Although targeted cost containment for postarrest interventions may reduce the finance burden, there is an increasing need for funding research into prediction and prevention of cardiac arrest, which offers greater societal benefit. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2018 Category: Cardiology Authors: Damluji, A. A., Al-Damluji, M. S., Pomenti, S., Zhang, T. J., Cohen, M. G., Mitrani, R. D., Moscucci, M., Myerburg, R. J. Tags: Sudden Cardiac Death Original Articles Source Type: research

Oxidized CaMKII (Ca2+/Calmodulin-Dependent Protein Kinase II) Is Essential for Ventricular Arrhythmia in a Mouse Model of Duchenne Muscular Dystrophy [Original Articles]
Conclusions: Inhibition of reactive oxygen species or ox-CaMKII protects against proarrhythmic intracellular Ca2+ handling and prevents ventricular arrhythmia in a mouse model of Duchenne muscular dystrophy. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2018 Category: Cardiology Authors: Wang, Q., Quick, A. P., Cao, S., Reynolds, J., Chiang, D. Y., Beavers, D., Li, N., Wang, G., Rodney, G. G., Anderson, M. E., Wehrens, X. H. T. Tags: Arrhythmias, Animal Models of Human Disease, Cell Signaling/Signal Transduction, Oxidant Stress, Cardiomyopathy Original Articles Source Type: research

Electrical Substrates Driving Response to Cardiac Resynchronization Therapy: A Combined Clinical-Computational Evaluation [Original Articles]
Conclusions: Computer simulations revealed that intrinsic interventricular dyssynchrony is the dominant component of the electrical substrate driving the response to CRT. Intrinsic intraventricular dyssynchrony and any dyssynchrony during biventricular pacing play a minor role in this respect. This may facilitate patient-specific modeling for prediction of CRT response. Clinical Trial Registration: URL: https://www.clinicaltrials.gov. Unique identifier: NCT01270646. (Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 13, 2018 Category: Cardiology Authors: Huntjens, P. R., Ploux, S., Strik, M., Walmsley, J., Ritter, P., Haissaguerre, M., Prinzen, F. W., Delhaas, T., Lumens, J., Bordachar, P. Tags: Electrophysiology, Computational Biology, Heart Failure, Pacemaker Original Articles Source Type: research

April 9th Question [Challenge of the Week]
(Source: Circulation: Arrhythmia and Electrophysiology)
Source: Circulation: Arrhythmia and Electrophysiology - April 9, 2018 Category: Cardiology Authors: Noheria, A. Tags: Arrhythmias, Catheter Ablation and Implantable Cardioverter-Defibrillator Challenge of the Week Source Type: research