A Single-center Retrospective Cohort Study on Cesarean Section under General Anesthesia
ConclusionPregnancy with internal or surgical diseases is the most common reason for choosing GA for CS. High ASA grade and short gestation period were the related factors of high postoperative ICU ratio for parturients and low one-minute Apgar score for neonates. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - January 10, 2020 Category: General Medicine Source Type: research
Physiological Variables Associated with the Development of Acute Mountain Sickness
ConclusionThe ability to sustain SpO2 after altitude elevation and the increase of neutrophils were associated with the development of AMS in young males. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - January 10, 2020 Category: General Medicine Source Type: research
Antagonistic Effects of N-acetylcysteine on Mitogen-activated Protein Kinase Pathway Activation, Oxidative Stress and Inflammatory Responses in Rats with PM2.5 Induced Lung Injuries
ConclusionNAC can antagonize major MAPK pathway activation, lung oxidative stress and inflammatory injury induced by PM2.5 in rats. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - January 10, 2020 Category: General Medicine Source Type: research
Ontology: Footstone for Strong Artificial Intelligence
Publication date: December 2019Source: Chinese Medical Sciences Journal, Volume 34, Issue 4Author(s): Xiaolin Yang, Zhe Wang, Hongjie Pan, Yan ZhuAbstractIn the past ten years, the application of artificial intelligence (AI) in biomedicine has increased rapidly, which roots in the rapid growth of biomedicine data, the improvement of computing performance, and the development of deep learning methods. At present, there are great difficulties in front of AI for solving complex and comprehensive medical problems. Ontology can play an important role in how to make machines have stronger intelligence and has wider applications ...
Source: Chinese Medical Sciences Journal - January 10, 2020 Category: General Medicine Source Type: research
An Optimized Protocol of Azoxymethane-Dextran Sodium Sulfate Induced Colorectal Tumor Model in Mice
Publication date: December 2019Source: Chinese Medical Sciences Journal, Volume 34, Issue 4Author(s): Xi Liang, Jingnan Hu, Jianming HeAbstractSince azoxymethane (AOM)-dextran sodium sulfate (DSS) induced tumorigenesis was used to explore inflammation-associated carcinogenesis of sporadic colorectal cancer (CRC), different administration modes of AOM or DSS have been reported. In this article we optimized the protocol of the AOM-DSS modeling using C57BL/6 mice for study on sporadic CRC by intraperitoneal injecting AOM solution at a proper concentration with a 100 μl sterile syringe once, feeding with DSS solution for 7 da...
Source: Chinese Medical Sciences Journal - January 10, 2020 Category: General Medicine Source Type: research
Anesthetic Considerations in a 98-year-old Man with Periprosthetic Femoral Shaft Fracture
Publication date: December 2019Source: Chinese Medical Sciences Journal, Volume 34, Issue 4Author(s): Si Chen, Lijian PeiAbstractA 98-year-old male patient with history of hemiarthroplasty suffered periprosthetic fracture of right femoral shaft and developed acute coronary event in three days after hospitalization. Femoral nerve and lateral femoral cutaneous nerve blocks combined with general anesthesia were implemented for the internal fixation surgery. The recovery was uneventful after discharge. In this case report, we discussed the main considerations of anesthesia specifically for this complicated case. (Source: Chine...
Source: Chinese Medical Sciences Journal - January 10, 2020 Category: General Medicine Source Type: research
Bevacizumab Combined with Icotinib Overcomes Osimertinib Resistance in a Patient of Non-Small Cell Lung Cancer
Publication date: December 2019Source: Chinese Medical Sciences Journal, Volume 34, Issue 4Author(s): Ling Zhang, Lei Sun, Xiaoyan Mu, Youxin JiAbstractA 61-year-old Chinese woman was diagnosed as primary pulmonary adenocarcinoma of left superior lobe with epidermal growth factor receptor (EGFR) 19 del mutation positive. Treatment with icotinib was given, but her disease progressed after 6 months remission. CT-guide needle biopsy for the new lesion in inferior lobe of left lung demonstrated intrapulmonary metastasis, and EGFR gene panel by Amplification Refractory Mutation System Polymerase Chain Reaction (ARMS-PCR) confir...
Source: Chinese Medical Sciences Journal - January 10, 2020 Category: General Medicine Source Type: research
A Severe Case of Reye's Syndrome with Multiorgan Dysfunction after Epstein-Barr Virus Infection
Publication date: December 2019Source: Chinese Medical Sciences Journal, Volume 34, Issue 4Author(s): Bingnan Liu, Ying QiAbstractA 20-month-old male infant with multiorgan dysfunction after Epstein-Barr virus (EBV) infection developed Reye's syndrome. He also suffered from acute liver failure, life-threatening cerebral edema, severe disseminated intravascular coagulation (DIC), and myocardial involvement. EBV infection aggravated the progress of Reye's syndrome, leading to death despite full supportive and symptomatic therapy. This critical case suggested that pediatricians should pay attention to multiorgan involvement o...
Source: Chinese Medical Sciences Journal - January 10, 2020 Category: General Medicine Source Type: research
Regional Differences of the Urinary Proteomes in Healthy Chinese Individuals
ConclusionsUrimem will facilitate urinary protein storage for large-scale urine sample collection. Regional differences are a confounding factor influencing the urine proteome and should be considered in future multi-center biomarker studies. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - October 16, 2019 Category: General Medicine Source Type: research
Identification of CDK6 and RHOU in Serum Exosome as Biomarkers for the Invasiveness of Non-functioning Pituitary Adenoma
ConclusionsCDK6 and RHOU mRNA in serum exosomes can be used as markers for predicting invasiveness of NF-PAs. Combination of the two genes performs better in distinguishing INF-PAs from NNF-PAs. These results indicate CDK6 and RHOU play important roles in the invasiveness of NF-PAs, and the established diagnostic method is valuable for directing the clinical screening and postoperative treatment. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - October 16, 2019 Category: General Medicine Source Type: research
Five-year Clinical Outcomes of CAD Patients Complicated with Diabetes after StentBoost-optimized Percutaneous Coronary Intervention
ConclusionsStentBoost could effectively improve instant PCI results; the long-term clinical outcomes of StentBoost-optimized PCI were similar between diabetic and non-diabetic patients. Age and left ventricular ejection fraction were the independent predictors for long-term clinical outcomes. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - October 16, 2019 Category: General Medicine Source Type: research
Downregulation of iASPP Expression Suppresses Proliferation, Invasion and Increases Chemosensitivity to Paclitaxel of Head and Neck Squamous Cell Carcinoma In Vitro
ConclusionThese results suggest iASPP may play an important role in progression and aggressive behavior of HNSCC and may be an efficient chemotherapeutic target for the treatment of HNSCC. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - October 16, 2019 Category: General Medicine Source Type: research
Value of CT-Angiography in the Emergency Management of Severe Hemoptysis
ConclusionsMDCTA provides useful information for identifying the anatomical characteristics of bleeding-related BAs and nonbronchial systemic arteries for the management of patients with severe hemoptysis. However, MDCTA could not determine the individuals who need BAE through measuring diameter of BAs. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - October 16, 2019 Category: General Medicine Source Type: research
IL-36β Promotes Inflammatory Activity and Inhibits Differentiation of Keratinocytes In Vitro
ConclusionTaken together, these findings suggest that IL-36β could induce cell cycle arrest at S phase, inhibit keratin 10 and involucrin expressions and promote inflammatory activity in HaCaT cell lines. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - October 16, 2019 Category: General Medicine Source Type: research
Association between GSTT1 Homozygous Deletion and Risk of Pancreatic Cancer: A Meta Analysis
ConclusionGSTT1 homozygous deletion individuals may have higher susceptibility to pancreatic cancer. (Source: Chinese Medical Sciences Journal)
Source: Chinese Medical Sciences Journal - October 16, 2019 Category: General Medicine Source Type: research
