Erythrocytosis caused by giant chromophobe renal cell carcinoma: a case report indicating a 9-year misdiagnosis of polycythemia vera.
CONCLUSIONS: Chromophobe renal cell carcinoma could cause erythrocytosis, but the clear-cut mechanism needs further research. Secondary erythrocytosis such as those related with renal tumors should be taken into consideration during the diagnosis of polycythemia vera.
PMID: 28877745 [PubMed - in process] (Source: Chinese Journal of Cancer)
Source: Chinese Journal of Cancer - September 9, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
Potential factors associated with clinical stage of nasopharyngeal carcinoma at diagnosis: a case-control study.
CONCLUSIONS: Initiatives to improve NPC patient prognosis should aim to promote knowledge about early symptoms and detection, health awareness, and accessibility to health facilities among all patients, regardless of socioeconomic status.
PMID: 28870229 [PubMed - in process] (Source: Chinese Journal of Cancer)
Source: Chinese Journal of Cancer - September 6, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
Erratum to: Cancer chemoprevention through dietary flavonoids: what's limiting?
Authors: Amawi H, Ashby CR, Tiwari AK
PMID: 28854960 [PubMed - in process] (Source: Chinese Journal of Cancer)
Source: Chinese Journal of Cancer - September 2, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
The 150 most important questions in cancer research and clinical oncology series: questions 50-56.
Authors: Chinese Journal of Cancer
Abstract
Since the beginning of 2017, Chinese Journal of Cancer has published a series of important questions in cancer research and clinical oncology, which sparkle diverse thoughts, interesting communications, and potential collaborations among researchers all over the world. In this article, seven more questions are presented as followed. Question 50. When tumor cells spread from primary site to distant sites, are they required to be "trained" or "armed" in the bone marrow niche prior to colonizing soft tissues? Question 51. Are there tipping points during cancer progr...
Source: Chinese Journal of Cancer - August 31, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
At-home cancer screening: a solution for China and other developing countries with a large population and limited number of healthcare practitioners.
Authors: Qian CN
Abstract
Five-year survival rate for patients with all cancers combined, in China, is only 30.9%, which is much lower than those in developed countries. The three main reasons for the low cancer curative rates in China include differences in the spectrum of cancer types, in early detection rates, and in the percentage of cancer patients receiving standardized treatment between China and developed countries. The most important mechanism for improving the curative rate is to improve early detection rates of major cancers in China using novel and affordable technologies that can be operated a...
Source: Chinese Journal of Cancer - August 24, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
Awakening immunity against cancer: a 2017 primer for clinicians.
Authors: Jain A, Zhang Q, Toh HC
Abstract
Cancer immunotherapy has finally joined the pillars of cancer treatment-surgery, radiation, chemotherapy, hormonal therapy, and targeted therapy-in improving cancer patient lives. In the last 5 years, the development of immune checkpoint inhibitor and T cell therapy, particularly chimeric antigen receptor (CAR) T-cell therapy, has been remarkable for the speed, scale, and number of drug approvals. Still, these treatments may also bring unusual adverse effects and clinical outcomes including unprecedented long-term survival. Interrogating the tumor microenvironment...
Source: Chinese Journal of Cancer - August 23, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
Immunohistochemical prognostic markers of esophageal squamous cell carcinoma: a systematic review.
CONCLUSION: Strong evidence supports that these 11 emerging IHC markers or their combinations may be useful in predicting prognosis and aiding personalized therapy decision-making for ESCC patients.
PMID: 28818096 [PubMed - in process] (Source: Chinese Journal of Cancer)
Source: Chinese Journal of Cancer - August 20, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
Estimates of cancer incidence and mortality in China, 2013.
CONCLUSIONS: Cancer leaves serious disease burden in China with high incidence and mortality. Lung cancer was the most common cancer and the leading cause of cancer death in China. Efficient control strategy is needed, especially for major cancers.
PMID: 28818111 [PubMed - in process] (Source: Chinese Journal of Cancer)
Source: Chinese Journal of Cancer - August 20, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
Comparison of efficacy, safety, and quality of life between sorafenib and sunitinib as first-line therapy for Chinese patients with metastatic renal cell carcinoma.
CONCLUSIONS: Sorafenib has comparable efficacy and lower toxicity profile than sunitinib as first-line therapy for mRCC. Both agents showed no significant impact on QoL of patients.
PMID: 28789709 [PubMed - in process] (Source: Chinese Journal of Cancer)
Source: Chinese Journal of Cancer - August 10, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
Synthetic lethal short hairpin RNA screening reveals that ring finger protein 183 confers resistance to trametinib in colorectal cancer cells.
CONCLUSION: The RNF183-IL-8 axis is responsible for the resistance of CRC cells to the MEK1/2 inhibitor trametinib and may serve as a candidate target for combined therapy for CRC.
PMID: 28756770 [PubMed - in process] (Source: Chinese Journal of Cancer)
Source: Chinese Journal of Cancer - August 1, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
Prognostic role of ABO blood type in patients with extranodal natural killer/T cell lymphoma, nasal type: a triple-center study.
CONCLUSIONS: ABO blood type was an independent predictor of clinical outcome for patients with ENKTL.
PMID: 28756771 [PubMed - in process] (Source: Chinese Journal of Cancer)
Source: Chinese Journal of Cancer - August 1, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
Prognostic value of programmed death-1, programmed death-ligand 1, programmed death-ligand 2 expression, and CD8(+) T cell density in primary tumors and metastatic lymph nodes from patients with stage T1-4N+M0 gastric adenocarcinoma.
CONCLUSION: The expression of PD-L1 is heterogeneous in primary tumors and in metastatic lymph nodes from patients with stage T1-4N+M0 gastric adenocarcinoma, which might explain the inconsistent results in assessing the prognostic value of PD-L1 expression in previous studies.
PMID: 28754154 [PubMed - in process] (Source: Chinese Journal of Cancer)
Source: Chinese Journal of Cancer - July 31, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
Spatio-temporal analysis of the incidence of colorectal cancer in Guangzhou, 2010-2014.
CONCLUSIONS: This study revealed the spatio-temporal cluster pattern of the incidence of CRC in Guangzhou. This information can inform allocation of health resources for CRC screening.
PMID: 28754180 [PubMed - in process] (Source: Chinese Journal of Cancer)
Source: Chinese Journal of Cancer - July 31, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
Transarterial chemoembolization combined with recombinant human adenovirus type 5 H101 prolongs overall survival of patients with intermediate to advanced hepatocellular carcinoma: a prognostic nomogram study.
CONCLUSIONS: TACE plus H101 extends the survival of patients with intermediate to advanced HCC. Our proposed nomogram provides individual survival prediction and stratification for patients with intermediate to advanced HCC who receive TACE with or without H101.
PMID: 28728568 [PubMed - in process] (Source: Chinese Journal of Cancer)
Source: Chinese Journal of Cancer - July 22, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
Mortality outcomes of low-dose computed tomography screening for lung cancer in urban China: a decision analysis and implications for practice.
CONCLUSIONS: In terms of mortality outcomes, our findings favor conducting low-dose CT screening in urban China. However, approaches to reducing false diagnoses and optimizing important screening conditions such as enrollment criteria for screening are highly needed.
PMID: 28709441 [PubMed - in process] (Source: Chinese Journal of Cancer)
Source: Chinese Journal of Cancer - July 17, 2017 Category: Cancer & Oncology Tags: Chin J Cancer Source Type: research
