Co-ordinated mitochondrial degradation by autophagy and heterophagy in cardiac homeostasis
AutophagyMacrophageMitochondriaMetabolismHeart (Source: Cardiovascular Research)
Source: Cardiovascular Research - January 4, 2021 Category: Cardiology Source Type: research
Colchicine in coronary disease: another renaissance of an ancient drug
Coronary diseaseInflammationColchicineClinical trials (Source: Cardiovascular Research)
Source: Cardiovascular Research - December 29, 2020 Category: Cardiology Source Type: research
Platelet CXCL14: introducing a new player and potential therapeutic target in thromboinflammation
This editorial refers to ‘The chemokine CXCL14 mediates platelet function and migration via direct interaction with CXCR4’ by A. Witteet al., pp.903 –917. (Source: Cardiovascular Research)
Source: Cardiovascular Research - December 26, 2020 Category: Cardiology Source Type: research
Scientists on the Spot: RNA modifications in atherosclerosis
(Source: Cardiovascular Research)
Source: Cardiovascular Research - December 26, 2020 Category: Cardiology Source Type: research
Circulating uromodulin: a cytokine trap for osteoinductive inflammatory mediators in chronic kidney disease?
This editorial refers to ‘Circulating uromodulin inhibits vascular calcification by interfering with pro-inflammatory cytokine signaling’ by I. Alesutanet al., pp.930 –941. (Source: Cardiovascular Research)
Source: Cardiovascular Research - December 24, 2020 Category: Cardiology Source Type: research
Estrogen: reducing the pressure by arginine vasopressin
This editorial refers to ‘Estrogen inhibits salt-dependent hypertension by suppressing GABAergic excitation in magnocellular AVP neurons’, by X. Jinet al., pp. 2263 –2274. (Source: Cardiovascular Research)
Source: Cardiovascular Research - December 22, 2020 Category: Cardiology Source Type: research
Erratum to: TNAP as a therapeutic target for cardiovascular calcification: a discussion of its pleiotropic functions in the body
DOI:10.1093/cvr/cvaa299 (Source: Cardiovascular Research)
Source: Cardiovascular Research - December 22, 2020 Category: Cardiology Source Type: research
NRF2: a key regulator of endothelial microRNA transcription
This editorial refers to ‘NRF2 is a key regulator of endothelial microRNA expression under proatherogenic stimuli’ by S. Linna-Kuosmanenet al., pp.1339 –1357. (Source: Cardiovascular Research)
Source: Cardiovascular Research - December 22, 2020 Category: Cardiology Source Type: research
They eat, what we eat, they digest, what we ingest: the microbiome and the vulnerable plaque
This editorial refers to ‘Plasma levels of trimethylamine-N-oxide can be increased with ‘healthy’ and ‘unhealthy’ diets and do not correlate with the extent of atherosclerosis but with plaque instability’ by Y.C, Koayet al., pp. 435 –449. (Source: Cardiovascular Research)
Source: Cardiovascular Research - December 3, 2020 Category: Cardiology Source Type: research
Obesity, kidney dysfunction, and inflammation: interactions in hypertension
AbstractObesity contributes 65 –75% of the risk for human primary (essential) hypertension (HT) which is a major driver of cardiovascular and kidney diseases. Kidney dysfunction, associated with increased renal sodium reabsorption and compensatory glomerular hyperfiltration, plays a key role in initiating obesity-HT and target organ injury. Mediators of kidney dysfunction and increased blood pressure include (i) elevated renal sympathetic nerve activity (RSNA); (ii) increased antinatriuretic hormones such as angiotensin II and aldosterone; (iii) relative deficiency of natriuretic hormones; (iv) renal compression by fat i...
Source: Cardiovascular Research - December 1, 2020 Category: Cardiology Source Type: research
Insights into therapeutic products, preclinical research models, and clinical trials in cardiac regenerative and reparative medicine: where are we now and the way ahead. Current opinion paper of the ESC Working Group on Cardiovascular Regenerative and Reparative Medicine
We report herein the main ideas and conclusions of that meeting. (Source: Cardiovascular Research)
Source: Cardiovascular Research - December 1, 2020 Category: Cardiology Source Type: research
Scientists on the Spot: Inflammation in atherosclerosis
InflammationImmunomodulatoryAtherosclerosisESCCouncil on Basic Cardiovascular Science (Source: Cardiovascular Research)
Source: Cardiovascular Research - December 1, 2020 Category: Cardiology Source Type: research
Life course psychological distress and cardiovascular disease risk factors in middle age: birth cohort study
Recent findings suggest that psychological distress in childhood —a combination of symptoms of anxiety and depression—particularly when persistent across the life course is related to an elevated rate of cardiovascular disease mortality in older age.1 Several mechanisms have been implicated with one possibility being that people who experience distress in early life, and particularly its recurrence across the life course, may become more susceptible to vascular disease via differences in physiological development. There is, however, a paucity of studies holding data on early distress and biological risk factors for car...
Source: Cardiovascular Research - November 27, 2020 Category: Cardiology Source Type: research
The endothelium as Achilles ’ heel in COVID-19 patients
COVID-19HeartEndothelial cellsEndotheliitis (Source: Cardiovascular Research)
Source: Cardiovascular Research - November 27, 2020 Category: Cardiology Source Type: research
A vitaminic boost to rock the aortic wall
This editorial refers to ‘Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD+/nicotinamide ’ by T. Horimatsuet al., pp. 2226 –2238. (Source: Cardiovascular Research)
Source: Cardiovascular Research - November 27, 2020 Category: Cardiology Source Type: research
