The Evolving Clinical Testing Landscape of Genomic Aberrations in Solid Tumors and Hematological Malignancies – Insights from Evidence-Based Reviews for B-ALL and Breast, Brain, and Renal Cell Neoplasia
Publication date: Available online 28 April 2020Source: Cancer GeneticsAuthor(s): Patricia Miron, Min Fang (Source: Cancer Genetics)
Source: Cancer Genetics - April 28, 2020 Category: Cancer & Oncology Source Type: research
Double Mutation of Apc and Brca1 in an Italian Family
Publication date: Available online 28 April 2020Source: Cancer GeneticsAuthor(s): Maria Teresa Vietri, Giovanna D'Elia, Gemma Caliendo, Amelia Casamassimi, Marianna Resse, Luana Passariello, Michele Cioffi, Anna Maria Molinari (Source: Cancer Genetics)
Source: Cancer Genetics - April 28, 2020 Category: Cancer & Oncology Source Type: research
Evidence-Based Review of Genomic Aberrations in B-Lymphoblastic Leukemia/Lymphoma: Report from the Cancer Genomics Consortium Working Group for Lymphoblastic Leukemia
Publication date: Available online 21 March 2020Source: Cancer GeneticsAuthor(s): Yassmine Akkari, Helene Bruyere, Tanner R. Hagelstrom, Rashmi Kanagal-Shamanna, Jie Liu, Minjie Luo, Fady M. Mikhail, Beth Pitel, Gordana Raca, Mary Shago, Lina Shao, Lisa R. Smith, Teresa A. Smolarek, Ashwini Yenamandra, Linda B. Baughn (Source: Cancer Genetics)
Source: Cancer Genetics - March 21, 2020 Category: Cancer & Oncology Source Type: research
Characterizing false-positive fluorescence in situ hybridization results by mate-pair sequencing in a patient with chronic myeloid leukemia and progression to myeloid blast crisis
Publication date: Available online 17 March 2020Source: Cancer GeneticsAuthor(s): Jaime L. Lopes, Matthew Webley, Beth A. Pitel, Kathryn E. Pearce, James B. Smadbeck, Sarah H. Johnson, George Vasmatzis, William R. Sukov, Patricia T. Greipp, Nicole L. Hoppman, Rhett P. Ketterling, Linda B. Baughn, Laura Finn, Jess F. Peterson (Source: Cancer Genetics)
Source: Cancer Genetics - March 18, 2020 Category: Cancer & Oncology Source Type: research
Comparison of Four Next Generation Sequencing Platforms for Fusion Detection: Oncomine by ThermoFisher, AmpliSeq by Illumina, FusionPlex by ArcherDX, and QIAseq by QIAGEN
Publication date: Available online 7 March 2020Source: Cancer GeneticsAuthor(s): Xiaoyu Qu, Cecilia Yeung, Ilsa Coleman, Peter S Nelson, Min Fang (Source: Cancer Genetics)
Source: Cancer Genetics - March 7, 2020 Category: Cancer & Oncology Source Type: research
Novel and recurrent germline mutations in the VHL gene in 5 Arab patients with Von Hippel-Lindau disease
Publication date: Available online 6 March 2020Source: Cancer GeneticsAuthor(s): Muhammad Faiyaz-Ul-Haque, Masood Jamil, Muhammad Aslam, Halah Abalkhail, Fouad Al-Dayel, Sulman Basit, Zafar Nawaz, Syed H.E. Zaidi (Source: Cancer Genetics)
Source: Cancer Genetics - March 6, 2020 Category: Cancer & Oncology Source Type: research
Copy Number Assessment in the Genomic Analysis of CNS Neoplasia: An Evidence-Based Review from the Cancer Genomics Consortium (CGC) Working Group on Primary CNS Tumors
Publication date: Available online 26 February 2020Source: Cancer GeneticsAuthor(s): Stewart G. Neill, Jennifer Hauenstein, Marilyn M. Li, Yajuan J Liu, Minjie Luo, Debra F. Saxe, Azra H. Ligon (Source: Cancer Genetics)
Source: Cancer Genetics - February 26, 2020 Category: Cancer & Oncology Source Type: research
Editorial Board
Publication date: April 2020Source: Cancer Genetics, Volume 242Author(s): (Source: Cancer Genetics)
Source: Cancer Genetics - February 26, 2020 Category: Cancer & Oncology Source Type: research
Integrating transcriptome-wide association study and copy number variation study identifies candidate genes and pathways for diffuse non-Hodgkin's lymphoma
Publication date: Available online 25 February 2020Source: Cancer GeneticsAuthor(s): Di Wu, Jing Zhao, Hong Ma, Meng-Chang Wang (Source: Cancer Genetics)
Source: Cancer Genetics - February 25, 2020 Category: Cancer & Oncology Source Type: research
BCL11A Gene Over-expression in High Risk Neuroblastoma
Publication date: Available online 12 February 2020Source: Cancer GeneticsAuthor(s): Iyad Sultan, Abdelghani Tbakhi (Source: Cancer Genetics)
Source: Cancer Genetics - February 13, 2020 Category: Cancer & Oncology Source Type: research
LINE-1 retrotransposon encoded ORF1p expression and promoter methylation in oral squamous cell carcinoma: a pilot study
Publication date: Available online 10 February 2020Source: Cancer GeneticsAuthor(s): Savita Budania, Debpali Sur, Jitendra Nangal, Sofia Pilli, Koel Mukherjee, Manash Biswas, Ramasare Prasad, Prabhat K. Mandal, Shilpi SaxenaAbstractOral squamous cell carcinoma (OSCC) is highly predominant in India due to excessive use of tobacco. Here we investigated Long INterpersed Element 1 (LINE or L1) retrotransposon activity in OSCC samples in the same population. There are almost 500,000 copies of L1 occupied around 30% of the human genome. Although most of them are inactive, around 150-200 copies are actively jumping in a human g...
Source: Cancer Genetics - February 12, 2020 Category: Cancer & Oncology Source Type: research
Editorial Board
Publication date: February 2020Source: Cancer Genetics, Volume 241Author(s): (Source: Cancer Genetics)
Source: Cancer Genetics - February 10, 2020 Category: Cancer & Oncology Source Type: research
Enrichment of atypical hyperdiploidy and IKZF1 deletions detected by SNP-microarray in high-risk Australian AIEOP-BFM B-cell acute lymphoblastic leukaemia cohort
Publication date: Available online 10 February 2020Source: Cancer GeneticsAuthor(s): Nadine K Berry, Rodney J Scott, Rosemary Sutton, Tamara Law, Toby N Trahair, Luce Dalla Pozza, Petra Ritchie, Draga Barbaric, Anoop K EnjetiAbstractAcute lymphoblastic leukaemia (ALL) is the most common childhood malignancy with the majority of patients being classified as B-cell lineage (B-ALL). The sub-classification of B-ALL is based on genomic architecture. Recent studies have demonstrated the capability of SNP-microarrays to detect genomic changes in B-ALL which cannot be observed by conventional cytogenetic methods. In current clinic...
Source: Cancer Genetics - February 10, 2020 Category: Cancer & Oncology Source Type: research
Current Concepts in Breast Cancer Genomics: An Evidence Based Review by the CGC Breast Cancer Working Group
Conclusion: A summary of currently available information on breast cancer genomics will enhance precision medicine by serving as an interpretive resource for clinical laboratory geneticists, providing a foundation for future practice guidelines, and identifying knowledge gaps to address in future research. (Source: Cancer Genetics)
Source: Cancer Genetics - February 8, 2020 Category: Cancer & Oncology Source Type: research
Kinetics of DNA damage repair response accompanying initial hepadnavirus-host genomic integration in woodchuck hepatitis virus infection of hepatocyte
Publication date: Available online 5 February 2020Source: Cancer GeneticsAuthor(s): Ranjit Chauhan, Tomasz I. MichalakAbstractMechanism of initial hepatitis B virus (HBV) integrations and kinetics of DNA repair immediately after infection remain essentially unknown impairing understanding of hepadnaviral oncogenesis. WCM260 hepatocytes susceptible to HBV-compatible woodchuck hepatitis virus (WHV) were examined from 15 min to 72 hours post-infection (p.i.). WHV strongly induced reactive oxygen species (ROS), transiently inducible nitric oxide (iNOS) and DNA damage from 15 min p.i. All initial WHV-host fusions had the head-t...
Source: Cancer Genetics - February 6, 2020 Category: Cancer & Oncology Source Type: research
