Comparison of hypersensitivity reactions of intravenous iron: iron isomaltoside ‐1000 (Monofer®) versus ferric carboxy‐maltose (Ferinject®). A single center, cohort study
British Journal of Clinical Pharmacology,Volume 0, Issue ja, -Not available-. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - November 5, 2018 Category: Drugs & Pharmacology Authors: M.B. Mulder, H.L. Hoek, E. Birnie, A.J.P. Tilburg, E.M. Westerman Source Type: research

Comparison of hypersensitivity reactions of intravenous iron: iron isomaltoside ‐1000 (Monofer®) versus ferric carboxy‐maltose (Ferinject®). A single center, cohort study
ConclusionsFerric carboxymaltose is associated with a 75% lower risk on HSRs compared with iron isomaltoside ‐1000 in our population. The presence of a comorbidity raises the likelihood of a HSR with a factor three regardless of the type of intravenous iron infusion. Further research is needed to clarify the underlying mechanism in various patient groups. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - November 4, 2018 Category: Drugs & Pharmacology Authors: M.B. Mulder, H.L. Hoek, E. Birnie, A.J.P. Tilburg, E.M. Westerman Tags: ORIGINAL ARTICLE Source Type: research

The Role of Vascular Endothelium in Nitroglycerin ‐Mediated Vasodilation
British Journal of Clinical Pharmacology,Volume 0, Issue ja, -Not available-. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - October 31, 2018 Category: Drugs & Pharmacology Authors: Kangbin Zhou, John D. Parker Source Type: research

The Role of Vascular Endothelium in Nitroglycerin ‐Mediated Vasodilation
ConclusionWe conclude that GTN ‐mediated dilation of forearm resistance vessels is largely independent of vascular endothelium. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - October 30, 2018 Category: Drugs & Pharmacology Authors: Kangbin Zhou, John D. Parker Tags: ORIGINAL ARTICLE Source Type: research

Pharmacological management of X ‐linked hypophosphataemia
The most common heritable disorder of renal phosphate wasting, X ‐linked hypophosphataemia (XLH), was discovered to be caused by inactivating mutations in the phosphate regulating gene with homology to endopeptidases on the X‐chromosome (PHEX) gene in 1995. Although the exact molecular mechanisms by whichPHEX mutations cause disturbed phosphate handling in XLH remain unknown, focus for novel therapies has more recently been based upon the finding that the bone ‐produced phosphaturic hormone fibroblast growth factor‐23 is elevated in XLH patient plasma. Previous treatment strategies for XLH were based upon phosphate...
Source: British Journal of Clinical Pharmacology - October 29, 2018 Category: Drugs & Pharmacology Authors: Erik A. Imel, Kenneth E. White Tags: REVIEW ‐THEMED ISSUE Source Type: research

Pharmacological management of X ‐linked hypophosphataemia
British Journal of Clinical Pharmacology, EarlyView. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - October 29, 2018 Category: Drugs & Pharmacology Authors: Erik A. Imel, Kenneth E. White Source Type: research

Inpatient toxicology services improve resource utilization for intoxicated patients: a systematic review
British Journal of Clinical Pharmacology, EarlyView. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - October 29, 2018 Category: Drugs & Pharmacology Authors: Robert G. Legg, Mark Little Source Type: research

Inpatient toxicology services improve resource utilization for intoxicated patients: a systematic review
ConclusionsThe presence of inpatient toxicology services appears to improve resource utilization, in reduction of length of stay, as well as a number of other related outcomes. It does this without compromising on patient morbidity or mortality. Thus, it should be considered as a potential model of care for future toxicology services, especially with current trends of increasing demand for service efficiency. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - October 28, 2018 Category: Drugs & Pharmacology Authors: Robert G. Legg, Mark Little Tags: SYSTEMATIC REVIEW AND META ‐ANALYSIS Source Type: research

An evaluation of the role of mixing techniques in the observed variation in acetylcysteine infusion concentrations
British Journal of Clinical Pharmacology,Volume 0, Issue ja, -Not available-. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - October 26, 2018 Category: Drugs & Pharmacology Authors: Kerry Layne, Louise Hope, Edmund Rab, J.R.H. Archer, David M. Wood, Paul I. Dargan Source Type: research

Pharmacokinetics and Pharmacodynamics of Ropinirole in Patients with Prolactinomas
British Journal of Clinical Pharmacology,Volume 0, Issue ja, -Not available-. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - October 26, 2018 Category: Drugs & Pharmacology Authors: Sihang Liu, Can Hu, Jane Peters, Amanda Tsang, Serge Cremers, Robert Bies, Gabrielle Page ‐Wilson Source Type: research

An evaluation of the role of mixing techniques in the observed variation in acetylcysteine infusion concentrations
British Journal of Clinical Pharmacology,Volume 0, Issue ja, -Not available-. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - October 26, 2018 Category: Drugs & Pharmacology Authors: Kerry Layne, Louise Hope, Edmund Rab, J.R.H. Archer, David M. Wood, Paul I. Dargan Source Type: research

Pharmacokinetics and Pharmacodynamics of Ropinirole in Patients with Prolactinomas
British Journal of Clinical Pharmacology,Volume 0, Issue ja, -Not available-. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - October 26, 2018 Category: Drugs & Pharmacology Authors: Sihang Liu, Can Hu, Jane Peters, Amanda Tsang, Serge Cremers, Robert Bies, Gabrielle Page ‐Wilson Source Type: research

Genetic Approaches to Metabolic Bone Diseases
British Journal of Clinical Pharmacology,Volume 0, Issue ja, -Not available-. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - October 25, 2018 Category: Drugs & Pharmacology Authors: Fadil M. Hannan, Paul J. Newey, Michael P. Whyte, Rajesh V. Thakker Source Type: research

Mechanisms that drive bone pain across the lifespan
British Journal of Clinical Pharmacology,Volume 0, Issue ja, -Not available-. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - October 25, 2018 Category: Drugs & Pharmacology Authors: Patrick W. Mantyh Source Type: research

Genetic Approaches to Metabolic Bone Diseases
British Journal of Clinical Pharmacology,Volume 0, Issue ja, -Not available-. (Source: British Journal of Clinical Pharmacology)
Source: British Journal of Clinical Pharmacology - October 25, 2018 Category: Drugs & Pharmacology Authors: Fadil M. Hannan, Paul J. Newey, Michael P. Whyte, Rajesh V. Thakker Source Type: research