Correlation of PET-CT, MRI and histopathology findings in the follow-up of patients with nasopharyngeal cancer
ConclusionsMagnetic resonance imaging and positron emission-computed tomography should be evaluated together in the follow-up of nasopharyngeal cancer. Patients with minimal SuvMax 4.58 on positron emission-computed tomography after contrast enhancement in the T2 sequence on magnetic resonance imaging may considered appropriate for biopsy. Biopsies in patients with a SuvMax value lower than 4.58 can be avoided. Thus, patients avoid surgical stress and unnecessary costs.ResumoIntroduçãoAs opções de tratamento cirúrgico são limitadas para o carcinoma nasofaríngeo por várias razões, incluindo aspectos epidemiológico...
Source: Brazilian Journal of Otorhinolaryngology - January 14, 2020 Category: ENT & OMF Source Type: research

Aquatic physiotherapy: a vestibular rehabilitation option
ConclusionIn conclusion, the aquatic physiotherapy protocol for vestibular rehabilitation of patients with peripheral impairment was positively assessed by the participants, considering the improvement in dizziness (static and dynamic) and its impact on daily activities.ResumoIntroduçãoA reabilitação vestibular se consolida como um recurso fundamental para o controle de sintomas vestibulares e sua realização no meio aquático é considerada segura para as atividades físicas dos idosos, atuando simultaneamente nas desordens musculoesqueléticas e na melhora do equilíbrio.ObjetivoAvaliar os efeitos de um protocolo de...
Source: Brazilian Journal of Otorhinolaryngology - January 14, 2020 Category: ENT & OMF Source Type: research

Difference between CD25+Tregs and Helios+Tregs in a murine model of allergic rhinitis
ConclusionThis is the first report of the proportions of Helios+Tregs in nasal mucosa and spleens of allergic rhinitis mice. Gating true inhibitory Tregs with the coexpression of Foxp3 and Helios might be more useful than relying on the expression of CD25. This study provides a new insight for Treg studies of allergic rhinitis, and the potential utility of the marker as a therapeutic target.ResumoIntroduçãoAs células reguladoras T, ou Treg, equilibram a resposta imune periférica aos alérgenos na rinite alérgica. Tradicionalmente, a célula Treg (CD25+Treg) é identificada pela co-expressão de Foxp3 e CD25, mas essa ...
Source: Brazilian Journal of Otorhinolaryngology - January 12, 2020 Category: ENT & OMF Source Type: research

Does the video head impulse test replace caloric testing?
Publication date: Available online 11 January 2020Source: Brazilian Journal of OtorhinolaryngologyAuthor(s): Alessandra Ramos Venosa, Mauricio Malavasi Ganança, Raquel Mezzalira, Roseli Saraiva Moreira Bittar, Fernando Freitas Ganança (Source: Brazilian Journal of Otorhinolaryngology)
Source: Brazilian Journal of Otorhinolaryngology - January 12, 2020 Category: ENT & OMF Source Type: research

The role of MMP-2 and MMP-9 in the metastasis and development of hypopharyngeal carcinoma
ConclusionThe expression of matrix metalloproteinase-2 and 9 in hypopharyngeal carcinoma was significantly higher than that in pericarcinoma tissue, and it was enhanced with the increase of clinical stage. The expression level was related to lymph node metastasis and tumor pathological stage. Thus, matrix metalloproteinase-2 and 9 may be involved in the occurrence, development, invasion and metastasis of hypopharyngeal carcinoma through a variety of mechanisms.ResumoIntroduçãoO papel da metaloproteinase da matriz 2 e9 nas metástases e no desenvolvimento de carcinoma hipofaríngeo ainda não foi esclarecido.ObjetivosObse...
Source: Brazilian Journal of Otorhinolaryngology - December 25, 2019 Category: ENT & OMF Source Type: research

The characteristics of otoacoustic emissions in full-term neonates according to ABO blood groups
ConclusionFemale individuals with blood group O have lower otoacoustic emissions values than individuals with the other three blood groups. We need to further investigate the possible relationships between ABO blood group and cochlear function, including the potential influences of noise damage on cochlear outer hair cells.ResumoIntroduçãoPesquisas anteriores sugeriram que indivíduos de diferentes grupos sanguíneos apresentam incidências distintas de perda auditiva induzida por ruído. As amplitudes reduzidas das emissões otoacústicas indicaram maiores ou menores possibilidades de danos às células ciliadas por exp...
Source: Brazilian Journal of Otorhinolaryngology - December 24, 2019 Category: ENT & OMF Source Type: research

Clinical characteristics for conservative therapy of pediatric parapharyngeal abscesses
ConclusionThe findings suggested that younger age, smaller abscess size, and less frequent antecedent illnesses, such as upper respiratory tract infection and lymphadenitis, could predict a successful response to conservative therapy in pediatric patients with parapharyngeal abscesses.ResumoIntroduçãoO papel da drenagem cirúrgicaversus tratamento conservador na abordagem de pacientes com abscessos parafaríngeos ainda é uma questão controversa.ObjetivosEste estudo teve como objetivo investigar as características associadas a um bom desfecho em pacientes pediátricos com abscessos parafaríngeos tratados com terapia c...
Source: Brazilian Journal of Otorhinolaryngology - December 24, 2019 Category: ENT & OMF Source Type: research

Pharyngeal motility in patients submitted to type I thyroplasty
ConclusionPharyngeal motility is affected by thyroplasty Type I in patients with dysphagia and low vagal injury.ResumoIntroduçãoA tireoplastia tipo 1 é realizada para melhorar o fechamento da glote e os sintomas disfágicos em pacientes com paralisia unilateral de prega vocal.ObjetivosEste estudo tem como objetivo comparar a motilidade da faringe e do esfíncter esofágico superior (ponto levantado nos comentários do revisor) em pacientes com paralisia unilateral de prega vocal antes e depois da tireoplastia tipo I.MétodoForam estudados prospectivamente 15 pacientes com paralisia unilateral de prega vocal submetidos Ã...
Source: Brazilian Journal of Otorhinolaryngology - December 18, 2019 Category: ENT & OMF Source Type: research

Assessment of HPV 16, HPV 18, p16 expression in advanced stage laryngeal cancer patients and prognostic significance
ConclusionThe close relationship between HPV and oropharyngeal squamous cell carcinoma could not be shown in larynx malignancy in many studies, including our study. Our findings support a limited role of HPV in laryngeal carcinogenesis. Protein16 is not a reliable surrogate for HPV status in laryngeal cancers and is not a predictor of laryngeal cancer survival. Supraglottic localization of tumor was determined to be increased in protein16 positive cases. The correlation between protein16 positivity and supraglottic area location was determined to be statistically significant. There is a need for more populated clinical tri...
Source: Brazilian Journal of Otorhinolaryngology - December 13, 2019 Category: ENT & OMF Source Type: research

Acute tissue damage induced by monopolar microelectrodes and radiofrequency in vocal cords after transoral cordectomy
ConclusionMicroelectrodes and radiofrequency in transoral laryngeal surgery produced mild tissue damage and offer an excellent alternative to the use of high frequency energy.ResumoIntroduçãoEm 2006 e 2009, relatamos os níveis de danos teciduais agudos e crônicos após cordectomia associados ao uso de microeletrodos utilizando energia de alta frequência. Em 2010, passamos a utilizar radiofrequência em vez de eletrogeradores de alta frequência.ObjetivoO objetivo deste estudo é avaliar a lesão tecidual aguda na laringe após cordectomia utilizando microeletrodos acoplados a um gerador de radiofrequência.MétodoFora...
Source: Brazilian Journal of Otorhinolaryngology - December 13, 2019 Category: ENT & OMF Source Type: research

Evaluation of cytogenetic damage in exfoliated nasal epithelial cells contributes to a better understanding the pathogenesis of rhinosinusitis
Publication date: Available online 10 December 2019Source: Brazilian Journal of OtorhinolaryngologyAuthor(s): Ana Carolina Flygare Souza, Carla Máximo Prado, Daniel Araki Ribeiro (Source: Brazilian Journal of Otorhinolaryngology)
Source: Brazilian Journal of Otorhinolaryngology - December 11, 2019 Category: ENT & OMF Source Type: research

Individuals with peripheral vestibulopathy and poor quality of sleep are at a higher risk for falls
ConclusionIndividuals with peripheral vestibulopathies and poor quality of sleep demonstrate worse balance evidenced by increased postural instability, higher risk of falls and worse perceived quality of life. The quality of sleep is a predictive factor for worse perceived quality of life and for higher risk of falls in individuals with peripheral vestibulopathies.ResumoIntroduçãoHá uma falta de estudos científicos sobre a avaliação de pacientes com distúrbios vestibulares relacionados a distúrbios da qualidade do sono e seu impacto sobre o equilíbrio e a qualidade de vida em geral.ObjetivosAvaliar o impacto da qu...
Source: Brazilian Journal of Otorhinolaryngology - December 11, 2019 Category: ENT & OMF Source Type: research

Prognostic value of 18F-FDG PET/CT parameters and histopathologic variables in head and neck cancer
ConclusionPretreatment quantities positron emission tomography parameters did not predict survival in head and neck cancer.ResumoIntroduçãoOs parâmetros da tomografia por emissão de pósitrons/tomografia computadorizada com 18F-fluordesoxiglicose, como os máximos valores de captação padronizados, o volume metabólico tumoral padrão e a glicólise total da lesão são importantes biomarcadores prognósticos de câncer.Objetivoinvestigar o valor prognóstico desses parâmetros em pacientes com câncer de cabeça e pescoço.MétodoRealizamos um estudo retrospectivo que incluiu 47 pacientes com câncer de cabeça e pes...
Source: Brazilian Journal of Otorhinolaryngology - December 11, 2019 Category: ENT & OMF Source Type: research

Platysma transverse myocutaneous flap: a 21 case series of an overlooked reconstructive method for facial skin defects
ConclusionSeveral factors may influence platysma transverse myocutaneous flap survival. Usually a long and narrow flap, especially crossing the neck midline and associated with neck dissection are more prone to poor outcomes.ResumoIntroduçãoDesde o primeiro relato de retalho miocutâneo transverso de platisma em 1977, poucos artigos sobre o assunto foram adicionados à literatura.ObjetivoNosso objetivo foi descrever a experiência de nosso departamento com retalho miocutâneo transverso de platisma.MétodoAnálise retrospectiva de todos os pacientes submetidos à reconstrução por retalho miocutâneo transverso de plati...
Source: Brazilian Journal of Otorhinolaryngology - December 11, 2019 Category: ENT & OMF Source Type: research

The incidence of thyroid gland invasion in advanced laryngeal squamous cell carcinoma
ConclusionsThyroidectomy may only be required during total laryngectomy for selected cases of advanced transglottic tumors and tumors with subglottic extension more than 10 mm.ResumoIntroduçãoEm geral, a invasão da glândula tireoide não é uma característica do carcinoma laríngeo avançado, não sendo necessário realizar tireoidectomia em todos os casos de laringectomia total.ObjetivosAvaliar a frequência da invasão da glândula tireoide em pacientes com carcinoma espinocelular avançado de laringe submetidos à laringectomia total e tireoidectomia e determinar se as características clínicas e histopatológic...
Source: Brazilian Journal of Otorhinolaryngology - December 10, 2019 Category: ENT & OMF Source Type: research