Preclinical transgenic and patient ‐derived xenograft models recapitulate the radiological features of human adamantinomatous craniopharyngioma
Brain Pathology, EarlyView. (Source: Brain Pathology)
Source: Brain Pathology - May 17, 2017 Category: Neurology Source Type: research
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Brain Pathology, Ahead of Print. (Source: Brain Pathology)
Source: Brain Pathology - May 17, 2017 Category: Neurology Source Type: research
Cytotoxic CD8+ T cell ablation enhances the capacity of regulatory T cells to delay viral elimination in Theiler's murine encephalomyelitis
Brain Pathology, EarlyView. (Source: Brain Pathology)
Source: Brain Pathology - May 12, 2017 Category: Neurology Source Type: research
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Brain Pathology, Ahead of Print. (Source: Brain Pathology)
Source: Brain Pathology - May 12, 2017 Category: Neurology Source Type: research
Cytotoxic CD8+ T cell ablation enhances the capacity of regulatory T cells to delay viral elimination in Theiler's murine encephalomyelitis
In conclusion, data revealed that the suppressive capacity of Treg on viral elimination is efficiently boosted by CD8‐depletion, which renders C57BL/6 mice susceptible to develop chronic neuroinfection and TMEV‐IDD. (Source: Brain Pathology)
Source: Brain Pathology - May 12, 2017 Category: Neurology Authors: Malgorzata Ciurkiewicz, Vanessa Herder, Muhammad Akram Khan, Ann ‐Kathrin Uhde, René Teich, Stephan Floess, Wolfgang Baumgärtner, Jochen Huehn, Andreas Beineke Tags: Research Article Source Type: research
Axonal loss in the multiple sclerosis spinal cord revisited
Brain Pathology, EarlyView. (Source: Brain Pathology)
Source: Brain Pathology - May 7, 2017 Category: Neurology Source Type: research
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Brain Pathology, Ahead of Print. (Source: Brain Pathology)
Source: Brain Pathology - May 7, 2017 Category: Neurology Source Type: research
TGF β pathway deregulation and abnormal phospho‐SMAD2/3 staining in hereditary cerebral hemorrhage with amyloidosis‐Dutch type
This article is protected by copyright. All rights reserved. (Source: Brain Pathology)
Source: Brain Pathology - May 1, 2017 Category: Neurology Authors: Laure Grand Moursel, Leon P. Munting, Linda M. van der Graaf, Sjoerd G. van Duinen, Marie ‐Jose T.H. Goumans, Uwe Ueberham, Remco Natté, Mark A. van Buchem, Willeke M.C. van Roon‐Mom, Louise van der Weerd Tags: Research Article Source Type: research
Preclinical transgenic and patient ‐derived xenograft models recapitulate the radiological features of human adamantinomatous craniopharyngioma
Conclusions: The Hesx1Cre/+;Ctnnb1l°x(ex3)/+ transgenic mouse model and cerebral patient‐derived ACP xenografts recapitulate a number of the key radiological features of the human disease and provide promising foundations for in vivo trials of novel therapeutics for the treatment of these tumours. This article is protected by copyright. All rights reserved. (Source: Brain Pathology)
Source: Brain Pathology - May 1, 2017 Category: Neurology Authors: Jessica K. R. Boult, John R. Apps, Annett H ölsken, J. Ciaran Hutchinson, Gabriela Carreno, Laura S. Danielson, Laura M. Smith, Tobias Bäuerle, Rolf Buslei, Michael Buchfelder, Alex K. Virasami, Alexander Koers, Owen J. Arthurs, Thomas S. Jacques, Louis Tags: Research Article Source Type: research
Loss of smarce1 expression is a specific diagnostic marker of clear cell meningioma: A comprehensive immunophenotypical and molecular analysis
In conclusion, our series showed, for the first time, that SMARCE1 immunostaining is a highly sensitive biomarker for CCM, useful as a routine diagnostic biomarker. This article is protected by copyright. All rights reserved. (Source: Brain Pathology)
Source: Brain Pathology - May 1, 2017 Category: Neurology Authors: Arnault Tauziede ‐Espariat, Béatrice Parfait, Aurore Besnard, Joëlle Lacombe, Johan Pallud, Sanaa Tazi, Stéphanie Puget, Guillaume Lot, Benoît Terris, Julie Cohen, Michel Vidaud, Dominique Figarella‐Branger, Franck Monnien, Marc Polivka, Homa Adle Tags: Research Article Source Type: research
Pericyte ‐derived Bone Morphogenetic Protein 4 Underlies White Matter Damage after Chronic Hypoperfusion
This article is protected by copyright. All rights reserved. (Source: Brain Pathology)
Source: Brain Pathology - May 1, 2017 Category: Neurology Authors: Maiko T Uemura, Masafumi Ihara, Takakuni Maki, Takayuki Nakagomi, Seiji Kaji, Kengo Uemura, Tomohiro Matsuyama, Raj N. Kalaria, Ayae Kinoshita, Ryosuke Takahashi Tags: Research Article Source Type: research
Cytotoxic CD8+ T cells ablation enhances the capacity of regulatory T cells to delay viral elimination in Theiler's murine encephalomyelitis
In conclusion, data revealed that the suppressive capacity of Treg on viral elimination is efficiently boosted by CD8‐depletion, which renders C57BL/6 mice susceptible to develop chronic neuroinfection and TMEV‐IDD. This article is protected by copyright. All rights reserved. (Source: Brain Pathology)
Source: Brain Pathology - April 28, 2017 Category: Neurology Authors: Malgorzata Ciurkiewicz, Vanessa Herder, Muhammad Akram Khan, Ann ‐Kathrin Uhde, René Teich, Stephan Floess, Wolfgang Baumgärtner, Jochen Huehn, Andreas Beineke Tags: Research Article Source Type: research
Characterising subtypes of hippocampal sclerosis and reorganization: correlation with pre and postoperative memory deficit
Abstract
Neuropathological subtypes of hippocampal sclerosis (HS) in temporal lobe epilepsy (The 2013 International League Against Epilepsy classification) are based on the qualitative assessment of patterns of neuronal loss with NeuN. In practice, some cases appear indeterminate between type 1 (CA1 and CA4 loss) and type 2 HS (CA1 loss) and we predicted that MAP2 would enable a more stringent classification. HS subtypes, as well as the accompanying alteration of axonal networks, regenerative capacity and neurodegeneration have been previously correlated with outcome and memory deficits and may provide prognostic clinic...
Source: Brain Pathology - April 24, 2017 Category: Neurology Authors: Anaclara Prada Jardim, Joan Liu, Jack Baber, Zuzanna Michalak, Cheryl Reeves, Matthew Ellis, Jan Novy, Jane de Tisi, Andrew McEvoy, Anna Miserocchi, Elza Marcia Targas Yacubian, Sanjay Sisodiya, Pamela Thompson, Maria Thom Tags: Research Article Source Type: research
Corrigendum
(Source: Brain Pathology)
Source: Brain Pathology - April 17, 2017 Category: Neurology Tags: CORRIGENDUM Source Type: research
Society news
(Source: Brain Pathology)
Source: Brain Pathology - April 17, 2017 Category: Neurology Tags: SOCIETY NEWS Source Type: research
