8-Formylophiopogonanone B antagonizes doxorubicin-induced cardiotoxicity by suppressing heme oxygenase-1-dependent myocardial inflammation and fibrosis
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Dan Qin, Rongchuan Yue, Ping Deng, Xiaobo Wang, Zaiyong Zheng, Mingming Lv, Yulong Zhang, Jun Pu, Jiqian Xu, Yidan Liang, Huifeng Pi, Zhengping Yu, Houxiang Hu (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 30, 2021 Category: Drugs & Pharmacology Source Type: research

Colossolactone-G synergizes the anticancer properties of 5-fluorouracil and gemcitabine against colorectal cancer cells
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Rinad A. Algehani, Raefa Abou Khouzam, Gehan A. Hegazy, Aliaa A. Alamoudi, Ali M. El-Halawany, Riham S. El Dine, Ghada A. Ajabnoor, Fahad A. Al-Abbasi, Mohammed A. Baghdadi, Ibrahim Elsayed, Masao Hattori, Ahmed M. Al-Abd (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 30, 2021 Category: Drugs & Pharmacology Source Type: research

The HIF-2α/PPARα pathway is essential for liraglutide-alleviated, lipid-induced hepatic steatosis
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Hou Wang, Lingling Wang, Yun Li, Shunkui Luo, Jianfang Ye, Zhanjin Lu, Xiaobin Li, Hongyun Lu (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 30, 2021 Category: Drugs & Pharmacology Source Type: research

Hsa-miR-605 regulates the proinflammatory chemokine CXCL5 in complex regional pain syndrome
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Richa Pande, Ayush Parikh, Botros Shenoda, Sujay Ramanathan, Guillermo M. Alexander, Robert J. Schwartzman, Seena K. Ajit (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 30, 2021 Category: Drugs & Pharmacology Source Type: research

PCSK9 and cancer: Rethinking the link
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Khadijeh Mahboobnia, Matteo Pirro, Ettore Marini, Francesco Grignani, Evgeny E. Bezsonov, Tannaz Jamialahmadi, Amirhossein Sahebkar (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 30, 2021 Category: Drugs & Pharmacology Source Type: research

Xenocoumacin 2 reduces protein biosynthesis and inhibits inflammatory and angiogenesis-related processes in endothelial cells
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Pelin Erkoc, Michaela Schmitt, Rebecca Ingelfinger, Iris Bischoff-Kont, Larissa Kopp, Helge B. Bode, Susanne Schiffmann, Robert Fürst (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 30, 2021 Category: Drugs & Pharmacology Source Type: research

Anti-inflammatory and analgesic actions of bufotenine through inhibiting lipid metabolism pathway
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Jiaojiao Wang, Dihui Xu, Lili Shen, Jing Zhou, Xiang Lv, Hongyue Ma, Nianguang Li, Qinan Wu, Jinao Duan (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 30, 2021 Category: Drugs & Pharmacology Source Type: research

Antibacterial and antibiotic modifying activity, ADMET study and molecular docking of synthetic chalcone (E)-1-(2-hydroxyphenyl)-3-(2,4-dimethoxy-3-methylphenyl)prop-2-en-1-one in strains of Staphylococcus aureus carrying NorA and MepA efflux pumps
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Janaína Esmeraldo Rocha, Thiago Sampaio de Freitas, Jayze da Cunha Xavier, Raimundo Luiz Silva Pereira, Francisco Nascimento Pereira Junior, Carlos Emídio Sampaio Nogueira, Márcia Machado Marinho, Paulo Nogueira Bandeira, Mateus Rodrigues de Oliveira, Emmanuel Silva Marinho, Alexandre Magno Rodrigues Teixeira Marinho, Hélcio Silva dos Santos Marinho, Henrique Douglas Melo Coutinho (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 30, 2021 Category: Drugs & Pharmacology Source Type: research

Metformin has no impact on nitric oxide production in patients with pre-diabetes
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Edyta Sutkowska, Paulina Fortuna, Bernadetta Kałuża, Karolina Sutkowska, Jerzy Wiśniewski, Andrzej Gamian Prof (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 30, 2021 Category: Drugs & Pharmacology Source Type: research

Pingchuan formula attenuates airway mucus hypersecretion via regulation of the PNEC-GABA-IL13-Muc5ac axis in asthmatic mice
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Xiang Piao, Shen-hua Jiang, Jia-ni Wang, Jie Wu, Wan-chao Xu, Li-qing Li, Zheng Xue, Jian-er Yu (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 30, 2021 Category: Drugs & Pharmacology Source Type: research

Main protease inhibitors and drug surface hotspots for the treatment of COVID-19: A drug repurposing and molecular docking approach
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Mahmudul Hasan, Md. Sorwer Alam Parvez, Kazi Faizul Azim, Md. Abdus Shukur Imran, Topu Raihan, Airin Gulshan, Samuel Muhit, Rubaiat Nazneen Akhand, Syed Sayeem Uddin Ahmed, Md Bashir Uddin (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 29, 2021 Category: Drugs & Pharmacology Source Type: research

Hippocampus kuda protein hydrolysate improves male reproductive dysfunction in diabetic rats
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Sabri Sudirman, Chieh-Yu Su, David Tsou, Meng-Chou Lee, Zwe-Ling Kong (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 29, 2021 Category: Drugs & Pharmacology Source Type: research

Danhong injection alleviates cerebral ischemia/reperfusion injury by improving intracellular energy metabolism coupling in the ischemic penumbra
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Miaolin Zeng, Huifen Zhou, Yu He, Zhixiong Wang, Chongyu Shao, Junjun Yin, Haixia Du, Jiehong Yang, Haitong Wan (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 29, 2021 Category: Drugs & Pharmacology Source Type: research

Network pharmacology identifies IL6 as an important hub and target of tibolone for drug repurposing in traumatic brain injury
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Andrew J. McGovern, George E. Barreto (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 29, 2021 Category: Drugs & Pharmacology Source Type: research

The active ingredients and mechanisms of Longchai Jiangxue Formula in treating PV, based on UPLC/Q-TOF-MS/MS, systematic pharmacology, and molecular biology validation
Publication date: August 2021Source: Biomedicine & Pharmacotherapy, Volume 140Author(s): Jing Ming, Weiyi Liu, Hongwei Wu, Yujin Li, Erpeng Yang, Ziqing Wang, Haiyan Xiao, Richeng Quan, Xiaomei Hu (Source: Biomedicine and Pharmacotherapy)
Source: Biomedicine and Pharmacotherapy - May 29, 2021 Category: Drugs & Pharmacology Source Type: research