The central role of glutathione peroxidase 4 in the regulation of ferroptosis and its implications for pro-inflammatory cytokine-mediated beta-cell death
Publication date: Available online 2 March 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Bastian Krümmel, Thomas Plötz, Anne Jörns, Sigurd Lenzen, Ilir Mehmeti (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - March 2, 2021 Category: Molecular Biology Source Type: research

Predominant cellular mitochondrial dysfunction in the TOP3A gene-caused Bloom syndrome-like disorder
Publication date: Available online 23 February 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Wenjun Jiang, Nan Jia, Chaowan Guo, Juan Wen, Lingqian Wu, Tomoo Ogi, Huiwen Zhang (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - February 23, 2021 Category: Molecular Biology Source Type: research

SUMOylation of mitofusins: a potential mechanism for perinuclear mitochondrial congression in cells treated with mitochondrial stressors
Publication date: Available online 19 February 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Catherine Kim, Meredith Juncker, Ryan Reed, Arthur Haas, Jessie Guidry, Michael Matunis, Wei-Chih Yang, Joshua Schwartzenburg, Shyamal Desai (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - February 20, 2021 Category: Molecular Biology Source Type: research

ISG15 attenuates post-translational modifications of mitofusins and congression of damaged mitochondria in Ataxia Telangiectasia cells
Publication date: Available online 19 February 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Meredith Juncker, Catherine Kim, Ryan Reed, Arthur Haas, Joshua Schwartzenburg, Shyamal Desai (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - February 20, 2021 Category: Molecular Biology Source Type: research

KAT8, lysine acetyltransferase 8, is required for adipocyte differentiation in vitro
Publication date: Available online 19 February 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Jasmine A. Burrell, Jacqueline M. Stephens (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - February 20, 2021 Category: Molecular Biology Source Type: research

Identification and characterization of two novel melanocortin-3 receptor mutations in Chinese obese individuals
Publication date: Available online 20 February 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Wei Wang, Yue-Jun Lin, Zhao-Xia Chen, Dong-Yu Guo (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - February 20, 2021 Category: Molecular Biology Source Type: research

The xenobiotic receptors PXR and CAR in liver physiology, an update
Publication date: Available online 15 February 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Xinran Cai, Gregory M. Young, Wen Xie (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - February 16, 2021 Category: Molecular Biology Source Type: research

Reduction in endoplasmic reticulum stress activates beige adipocytes differentiation and alleviates high fat diet-induced metabolic phenotypes
Publication date: Available online 6 February 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Ji-Min Lee, Soyoung Park, Duckgue Lee, Rehna Paula Ginting, Man Ryul Lee, Min-Woo Lee, Jaeseok Han (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - February 6, 2021 Category: Molecular Biology Source Type: research

Bezafibrate activation of PPAR drives disturbances in mitochondrial redox bioenergetics and decreases the viability of cells from patients with VLCAD deficiency
Publication date: Available online 5 February 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Martin Lund, Kathrine G. Andersen, Robert Heaton, Iain P. Hargreaves, Niels Gregersen, Rikke K.J. Olsen (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - February 5, 2021 Category: Molecular Biology Source Type: research

c-Abl activates RIPK3 signaling in Gaucher disease
Publication date: Available online 4 February 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): M.J. Yañez, F. Campos, T. Marín, A.D. Klein, A.H. Futerman, A.R. Alvarez, S. Zanlungo (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - February 4, 2021 Category: Molecular Biology Source Type: research

Connexins as therapeutic targets in neurological and neuropsychiatric disorders
Publication date: Available online 3 February 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): M. Charvériat, F. Mouthon, W. Rein, A. Verkhratsky (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - February 3, 2021 Category: Molecular Biology Source Type: research

Editorial Board
Publication date: 1 April 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Volume 1867, Issue 4Author(s): (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - February 2, 2021 Category: Molecular Biology Source Type: research

PPARs in liver physiology
Publication date: Available online 29 January 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Alexandre Berthier, Manuel Johanns, Francesco Paolo Zummo, Philippe Lefebvre, Bart Staels (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - January 30, 2021 Category: Molecular Biology Source Type: research

Sfxn1 is essential for erythrocyte maturation via facilitating hemoglobin production in zebrafish
Publication date: Available online 29 January 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Binghao Bao, Wenbin An, Qunwei Lu, Yaqin Wang, Zhichao Lu, Jiayi Tu, Heng Zhang, Yongjuan Duan, Weiping Yuan, Xiaofan Zhu, Haibo Jia (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - January 30, 2021 Category: Molecular Biology Source Type: research

Aberrant BCAA and glutamate metabolism linked to regional neurodegeneration in a mouse model of Leigh syndrome
Publication date: 1 May 2021Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Volume 1867, Issue 5Author(s): Karin Terburgh, Janeé Coetzer, Jeremy Z. Lindeque, Francois H. van der Westhuizen, Roan Louw (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - January 30, 2021 Category: Molecular Biology Source Type: research