Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Contribution of FP receptors in M1 macrophage polarization via IL-10-regulated nuclear translocation of NF-κB p65
Publication date: Available online 6 February 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsAuthor(s): Toko Maehara, Ko FujimoriAbstractMacrophages are the effector immune cells with plasticity to differentiate as M1 (classically activated) and M2 (alternatively activated) phenotypes. Prostaglandins (PGs) have various important roles and are involved in the regulation of macrophage activation. However, the role of PGF2α in macrophage activation remains unclear. We investigated the role of PGF2α receptor (FP)-mediated signaling in the M1 macrophage polarization using murine macropha...
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - February 7, 2020 Category: Lipidology Source Type: research

Enzymology of vertebrate carotenoid oxygenases
This article is part of a Special Issue entitled Carotenoids recent advances in cell and molecular biology edited by Johannes von Lintig and Loredana Quadro. (Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids)
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - February 6, 2020 Category: Lipidology Source Type: research

Mechanistic understanding of β-cryptoxanthin and lycopene in cancer prevention in animal models
This article is part of a Special Issue entitled Carotenoids recent advances in cell and molecular biology edited by Johannes von Lintig and Loredana Quadro. (Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids)
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - February 5, 2020 Category: Lipidology Source Type: research

The role of β-carotene and vitamin A in atherogenesis: Evidences from preclinical and clinical studies
This article is part of a Special Issue entitled Carotenoids recent advances in cell and molecular biology edited by Johannes von Lintig and Loredana Quadro. (Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids)
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - February 1, 2020 Category: Lipidology Source Type: research

The roles of autotaxin/lysophosphatidic acid in immune regulation and asthma
Publication date: Available online 29 January 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsAuthor(s): Seung-jae Kim, Hyung-Geun Moon, Gye Young ParkAbstractLysophosphatidic acid (LPA) species are present in almost all organ systems and play diverse roles through its receptors. Asthma is an airway disease characterized by chronic allergic inflammation where various innate and adaptive immune cells participate in establishing Th2 immune response. Here, we will review the contribution of LPA and its receptors to the functions of immune cells that play a key role in establishing allergi...
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - January 29, 2020 Category: Lipidology Source Type: research

Curcumin stimulates exosome/microvesicle release in an in vitro model of intracellular lipid accumulation by increasing ceramide synthesis
Publication date: Available online 25 January 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsAuthor(s): David García-Seisdedos, Bohdan Babiy, Milagros Lerma, María E. Casado, Javier Martínez-Botas, Miguel A. Lasunción, Óscar Pastor, Rebeca BustoAbstractCurcumin, a hydrophobic polyphenol found in the rhizome of Curcuma longa, has been shown to reduce intracellular lipid accumulation in mouse models of lysosomal storage diseases such as Niemann-Pick type C. Exosomes are small extracellular vesicles secreted by cells in response to changes in intracellular ceramide composition. Curc...
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - January 26, 2020 Category: Lipidology Source Type: research

Fargesin alleviates atherosclerosis by promoting reverse cholesterol transport and reducing inflammatory response
ConclusionThese results suggest that fargesin inhibits atherosclerosis by promoting RCT process and reducing inflammatory response via CEBPαS21/LXRα and TLR4/NF-κB pathways, respectively. (Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids)
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - January 26, 2020 Category: Lipidology Source Type: research

Dysregulation of microRNA-125a contributes to obesity-associated insulin resistance and dysregulates lipid metabolism in mice
Publication date: Available online 25 January 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsAuthor(s): Rui Liu, Meina Wang, Enjie Li, Yang Yang, Jiaxin Li, Siyu Chen, Wen-Jun Shen, Salman Azhar, Zhigang Guo, Zhigang HuAbstractObesity is associated with an increased risk of developing insulin resistance (IR) and type 2 diabetes (T2D). A diverse group of factors including miRNA has been implicated in the pathogenesis of these two metabolic conditions, although underlying molecular mechanisms involved are not well defined. Here, we provide evidence that hepatic miR-125a levels are dimin...
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - January 26, 2020 Category: Lipidology Source Type: research

FAHFA footprint in the visceral fat of mice across their lifespan
Publication date: Available online 25 January 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsAuthor(s): Quan-Fei Zhu, Jing-Wen Yan, Jian Ni, Yu-Qi FengAbstractFatty acid esters of hydroxy fatty acids (FAHFAs) are a new class of endogenous lipids with anti-inflammatory and anti-diabetic effects, having the potential to treat type 2 diabetes (T2D). In view of the important regulatory and therapeutic actions of FAHFAs on age-related diseases such as T2D, we hypothesized that they may also play crucial roles in the growth, development, and aging process. Here, we investigated the FAHFA fo...
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - January 26, 2020 Category: Lipidology Source Type: research

Editorial Board
Publication date: April 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Volume 1865, Issue 4Author(s): (Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids)
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - January 26, 2020 Category: Lipidology Source Type: research

A single nucleotide polymorphism of PLIN2 is associated with nonalcoholic steatohepatitis and causes phenotypic changes in hepatocyte lipid droplets: A pilot study
Publication date: Available online 23 January 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsAuthor(s): Claire S. Faulkner, Collin White, Vijay H. Shah, Loretta L. Jophlin (Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids)
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - January 23, 2020 Category: Lipidology Source Type: research

Lipidomic characterization of exosomes isolated from human plasma using various mass spectrometry techniques
Publication date: Available online 21 January 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsAuthor(s): Ondřej Peterka, Robert Jirásko, Michaela Chocholoušková, Ladislav Kuchař, Denise Wolrab, Roman Hájek, David Vrána, Ondřej Strouhal, Bohuslav Melichar, Michal HolčapekAbstractUltrahigh-performance supercritical fluid chromatography - mass spectrometry (UHPSFC/MS), ultrahigh-performance liquid chromatography - mass spectrometry (UHPLC/MS), and matrix-assisted laser desorption/ionization (MALDI) - MS techniques were used for the lipidomic characterization of exosomes isolated ...
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - January 23, 2020 Category: Lipidology Source Type: research

Molecular and cellular insights into the role of SND1 in lipid metabolism
Publication date: Available online 21 January 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of LipidsAuthor(s): Hiart Navarro-Imaz, Begoña Ochoa, Itsaso García-Arcos, María José Martínez, Yolanda Chico, Olatz Fresnedo, Yuri RuedaAbstractStaphylococcal nuclease and Tudor domain containing 1 (SND1) is an evolutionarily conserved protein present in eukaryotic cells from protozoa to mammals. SND1 has gained importance because it is overexpressed in aggressive cancer cells and diverse primary tumors. Indeed, it is regarded as a marker of cancer malignity. A broad range of molecular functions ...
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - January 23, 2020 Category: Lipidology Source Type: research

Role of carotenoids and retinoids during heart development
This article is part of a Special Issue entitled Carotenoids recent advances in cell and molecular biology edited by Johannes von Lintig and Loredana Quadro. (Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids)
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - January 23, 2020 Category: Lipidology Source Type: research

The role of β-carotene and vitamin A in atherogenesis: Evidences from pre-clinical and clinical studies
This article is part of a Special Issue entitled Carotenoids recent advances in cell and molecular biology edited by Johannes von Lintig and Loredana Quadro. (Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids)
Source: Biochimica et Biophysica Acta (BBA) Molecular and Cell Biology of Lipids - January 21, 2020 Category: Lipidology Source Type: research