Online access to abortion medications: a review of utilization and clinical outcomes
Publication date: Available online 2 July 2019Source: Best Practice & Research Clinical Obstetrics & GynaecologyAuthor(s): Margit Endler, Amanda Cleeve, Kristina Gemzell-Danielsson KAbstractWe performed a search in Pubmed and Web of Science on the self-use of abortion medication after online access. Studies published between January 1st 1995 and March 31st 2019 were considered. We included studies of online services that were (i) led by healthcare staff (n=14), (ii) led by non-healthcare staff (n=4), and (iii) providing non-interactive access (n=17). Our outcomes were utilization (frequency and demand for services), accept...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - July 4, 2019 Category: OBGYN Source Type: research

Abortion: professional responsibility beyond safe healthcare
Publication date: Available online 2 July 2019Source: Best Practice & Research Clinical Obstetrics & GynaecologyAuthor(s): Mahmoud F. Fathalla (Source: Best Practice and Research Clinical Obstetrics and Gynaecology)
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - July 4, 2019 Category: OBGYN Source Type: research

Improving blood transfusion services
Publication date: Available online 23 May 2019Source: Best Practice & Research Clinical Obstetrics & GynaecologyAuthor(s): Tara Tancred, Imelda BatesAbstractPostpartum haemorrhage contributes to 25% of maternal deaths worldwide, rising to 40% in sub-Saharan Africa. Treatment of postpartum haemorrhage—particularly for women with anaemia —requires timely, quality blood transfusions. There are a number of barriers to the provision of transfusion services, especially in low- and middle-income settings where the need is the greatest. These include unavailability of blood, unsafe blood, poor uptake of labour and delivery car...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - July 1, 2019 Category: OBGYN Source Type: research

The concern regarding the occurrence of fetal acidosis consequent to CO2 exposure during fetoscopy is unsubstantiated Endoscopic fetal surgery for neural tube defects
Publication date: Available online 29 June 2019Source: Best Practice & Research Clinical Obstetrics & GynaecologyAuthor(s): Denise Araujo LapaAbstractPrenatal repair of open spina bifida reduces shunt rates and may improve postnatal motor and neurodevelopmental outcomes. The hysterotomy required for the open fetal surgery leaves subsequent pregnancies at risk of uterine rupture. Hysterotomy site rupture confers significant morbidity and mortality risks for both mother and fetus. Fetoscopic repair is feasible and seems to achieve the same, postnatal neurological outcomes as those of the open repair. Fetoscopy can be accompl...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - July 1, 2019 Category: OBGYN Source Type: research

Current and potential methods for second trimester abortion
Publication date: Available online 25 May 2019Source: Best Practice & Research Clinical Obstetrics & GynaecologyAuthor(s): Klaira Lerma, Paul D. BlumenthalAbstractMedical and surgical methods can both be recommended for second trimester abortion (after 12-weeks of gestational age). Induced abortion with a mifepristone and misoprostol regimen is the preferred approach; where mifepristone is not available, misoprostol alone for medical abortion is also effective. Dilation and evacuation (D&E) is the procedure of choice for surgical abortions, and adequate cervical preparation contributes significantly to safety. Availability...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - June 29, 2019 Category: OBGYN Source Type: research

The Use of Immunomodulators to Treat Endometriosis
Publication date: Available online 29 June 2019Source: Best Practice & Research Clinical Obstetrics & GynaecologyAuthor(s): Alexander Kotlyar, Hugh Taylor, Thomas D’HoogheAbstractEndometriosis has been shown in both animal and human studies to exhibit numerous levels of immune dysfunction. From aberrant cytokine signaling to shifts in immune cell populations, it is clear that endometriosis develops in the setting of an elevated pro-inflammatory state. This elevated level of inflammation could exacerbate the morbidity seen in this chronic disease. As a consequence, numerous immunomodulating therapies have been tested in b...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - June 29, 2019 Category: OBGYN Source Type: research

Global Abortion Policies Database: a descriptive analysis of the regulatory and policy environment related to abortion
Publication date: Available online 26 June 2019Source: Best Practice & Research Clinical Obstetrics & GynaecologyAuthor(s): Antonella F. Lavelanet, Brooke Ronald Johnson, Bela GanatraAbstractThe World Health Organization (WHO) Safe abortion: technical and policy guidance for health systems states that regulatory, policy and programmatic barriers that hinder access to and timely provision of safe abortion care should be removed. While some regulatory requirements facilitate access, where they act as barriers, they can deter women from seeking safe abortion care. We use data available in the Global Abortion Policies Database...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - June 26, 2019 Category: OBGYN Source Type: research

What does basic science tell us about the use of uterotonics?
Publication date: Available online 24 June 2019Source: Best Practice & Research Clinical Obstetrics & GynaecologyAuthor(s): Thomas Drew, Mrinalini BalkiAbstractPharmacotherapy with uterotonics remains the mainstay of the management for post-partum haemorrhage. Clinical studies evaluating the efficacy of these drugs are fraught with confounders, which may influence uterine contractility and blood loss. For this reason, a range of techniques have been developed to study myometrial function in vitro, allowing for the comparison of various drugs in a controlled simulated physiological environment.In this review, we focus on th...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - June 25, 2019 Category: OBGYN Source Type: research

Immunomodulation and Preeclampsia
Publication date: Available online 24 June 2019Source: Best Practice & Research Clinical Obstetrics & GynaecologyAuthor(s): Marianna Rambaldi, Eran Weiner, Federico Mecacci, Jacob Bar, Felice PetragliaAbstractPreeclampsia (PE) is an enigmatic syndrome with still unknown etiology and multifactorial pathogenesis. Our understanding of the role of the immune system in PE development has undergone a transformation over the years. From a model based on the alterations in cell-mediated immunity, research moved on to a vision centered on the alteration of the humoral immunity and on the systemic involvement of the inflammatory sys...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - June 25, 2019 Category: OBGYN Source Type: research

Index
Publication date: May 2019Source: Best Practice & Research Clinical Obstetrics & Gynaecology, Volume 57Author(s): (Source: Best Practice and Research Clinical Obstetrics and Gynaecology)
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - June 20, 2019 Category: OBGYN Source Type: research

Renal disease and pregnancy – Multiple choice questions Vol. 57
Publication date: May 2019Source: Best Practice & Research Clinical Obstetrics & Gynaecology, Volume 57Author(s): (Source: Best Practice and Research Clinical Obstetrics and Gynaecology)
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - June 20, 2019 Category: OBGYN Source Type: research

Editorial Board
Publication date: May 2019Source: Best Practice & Research Clinical Obstetrics & Gynaecology, Volume 57Author(s): (Source: Best Practice and Research Clinical Obstetrics and Gynaecology)
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - June 20, 2019 Category: OBGYN Source Type: research

The CROWN Initiative: Journal editors invite researchers to develop core outcomes in women’s health
Publication date: May 2019Source: Best Practice & Research Clinical Obstetrics & Gynaecology, Volume 57Author(s): Khalid Khan, Chief Editors of Journals participating in The CROWN Initiative (Source: Best Practice and Research Clinical Obstetrics and Gynaecology)
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - June 20, 2019 Category: OBGYN Source Type: research

Operative vaginal delivery – Multiple choice questions Vol. 56
Publication date: May 2019Source: Best Practice & Research Clinical Obstetrics & Gynaecology, Volume 57Author(s): (Source: Best Practice and Research Clinical Obstetrics and Gynaecology)
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - June 20, 2019 Category: OBGYN Source Type: research

Fallopian tube subtle pathology
Publication date: Available online 7 January 2019Source: Best Practice & Research Clinical Obstetrics & GynaecologyAuthor(s): Jing Guan, Antoine WatrelotAbstractThe aim of the present review is to give a comprehensive overview of fallopian subtle lesions and suggest the impacts of these abnormalities on fertility. Tubal subtle variations, including tubal diverticula, Morgagni hydatids, accessory fallopian tube, accessory ostium of the fallopian tube, tubal phimosis, agglutination, and sacculation, have been described and cited as making significant contributions to infertility. This review summarizes characteristics of the...
Source: Best Practice and Research Clinical Obstetrics and Gynaecology - June 19, 2019 Category: OBGYN Source Type: research