Best Practice and Research. Clinical Endocrinology and Metabolism This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Volume-Outcome Relationship in Adrenal Surgery: A Review of Existing Literature
Publication date: Available online 12 July 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Hadiza S. Kazaure, Julie A. SosaAbstractThe relationship between operative volume and perioperative outcomes after several oncologic operations is well documented. Recent studies on adrenalectomy reveal a robust association between higher surgeon volume and improved patient outcomes. Statistical analyses have demonstrated that outcomes are improved when surgeons perform at least six adrenalectomies annually; based on this threshold definition of a ‘high-volume’ surgeon, more than 80% of adrenale...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - July 12, 2019 Category: Endocrinology Source Type: research

Pre- and intraoperative diagnostic requirements, benefits and risks of minimally invasive and robotic surgery for neuroendocrine tumors of the pancreas
Publication date: Available online 10 July 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Joseph Gharios, Elisabeth Hain, Anthony Dohan, Fréderic Prat, Benoit Terris, Jérôme Bertherat, Romain Coriat, Sébastien GaujouxAbstractPancreatic neuroendocrine tumours (PanNET) are rare tumours, accounting for 1% to 2% of all pancreatic neoplasms. These tumors are classified as functioning neuroendocrine tumours (F-PanNETs) or non-functioning (NF-PanNETs) depends on whether the tumour is associated with clinical hormonal hypersecretion syndrome or not. In the last decades, diagnosis of PanNETs ...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - July 11, 2019 Category: Endocrinology Source Type: research

The Epidemiology, Diagnosis And Treatment Of Prolactinomas:The Old And The New
Publication date: Available online 10 July 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Philippe Chanson, Dominique MaiterAbstractPrevalence and incidence of prolactinomas are approximately 50 per 100,000 and 3-5 new cases/100,000/year. The pathophysiological mechanism of hyperprolactinemia-induced gonadotropic failure involves kisspeptin neurons. Prolactinomas in males are larger, more invasive and less sensitive to dopamine agonists (DAs). Macroprolactin, responsible for pseudohyperprolactinemia is a frequent pitfall of prolactin assay.DAs still represent the primary therapy for most...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - July 11, 2019 Category: Endocrinology Source Type: research

Endoscopic, transanal, laparoscopic, and transabdominal management of rectal neuroendocrine tumors
Publication date: Available online 9 July 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Louis de Mestier, Diane Lorenzo, Caroline Fine, Jérôme Cros, Olivia Hentic, Thomas Walter, Yves Panis, Anne Couvelard, Guillaume Cadiot, Philippe RuszniewskiAbstractRectal neuroendocrine tumors (RNET) are rare tumors but their prevalence is constantly increasing due to a prolonged survival and rising incidence related to a growing number of colonoscopies and improved knowledge. Their main prognostic determinant is tumor stage. While most RNET are localized, their management should be tailored depen...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - July 10, 2019 Category: Endocrinology Source Type: research

The surgical dilemma of primary surgery for follicular thyroid neoplasms
Publication date: Available online 9 July 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Julia I. Staubitz, Petra B. Musholt, Thomas J. MusholtAbstractFollicular thyroid carcinoma is the second most prevalent form of differentiated thyroid carcinoma, following papillary thyroid carcinoma. Preoperative diagnosis is hampered by the fact that fine-needle aspiration cytology as well as supplemental molecular analysis cannot unambiguously distinguish between follicular thyroid carcinoma and benign follicular thyroid adenoma. The 2017 WHO classification defines three histological subtypes of f...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - July 10, 2019 Category: Endocrinology Source Type: research

Female Fertility preservation in DSD
Publication date: Available online 9 July 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Dr Rashi Kalra, Dr Melissa Cameron, Catharyn SternAbstractDisorders of sex development (DSD) are a group of complex conditions that can affect chromosomal, gonadal, and/or phenotypical sex with a highly variable fertility potential amongst affected individuals. In this review we discuss fertility issues facing patients affected by DSD and Turner syndrome and summarise the literature on fertility and reproductive outcomes. We will also discuss fertility preservation prior to gonadotoxic treatment in a...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - July 10, 2019 Category: Endocrinology Source Type: research

The impact of childhood cancer and its treatment on puberty and subsequent hypothalamic pituitary and gonadal function, in both boys and girls
Publication date: Available online 9 July 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Christina Wei, Elizabeth CrowneAbstractChildhood cancer survivors (CCS) are at an increased risk of endocrine disorders. Disorders of the hypothalamic-pituitary-gonadal (HPG) axis are a particular concern because of their impact on pubertal development and future fertility and may be of central (hypothalamic or pituitary damage) or primary (gonadal) origin. Hypogonadism may present as pubertal disorders during adolescence and subsequent infertility in adulthood but should be anticipated to ensure app...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - July 10, 2019 Category: Endocrinology Source Type: research

Volume–outcome relationship in parathyroid surgery
ConclusionsThere are insufficient data to dogmatically conclude a minimum number of cases required to achieve optimal surgical results. However, extrapolation from the inclusive studies support the conclusions that higher operative volumes improve cure rates and decrease the rates of complications, recurrent disease, and perioperative costs. Endocrine Surgery fellowships or mentorships may help prepare the less experienced surgeon for successful outcomes. Although reticent to offer firm minimal volume requirements, we have made suggestions in this manuscript. (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - July 6, 2019 Category: Endocrinology Source Type: research

Volume-Outcome Relationship in Parathyroid Surgery
ConclusionsThere are insufficient data to dogmatically conclude a minimum number of cases required to achieve optimal surgical results. However, extrapolation from the inclusive studies support the conclusions that higher operative volumes improve cure rates and decrease the rates of complications, recurrent disease, and perioperative costs. Endocrine Surgery fellowships or mentorships may help prepare the less experienced surgeon for successful outcomes. Although reticent to offer firm minimal volume requirements, we have made suggestions in this manuscript. (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 17, 2019 Category: Endocrinology Source Type: research

Editorial Board
Publication date: February 2019Source: Best Practice & Research Clinical Endocrinology & Metabolism, Volume 33, Issue 1Author(s): (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 15, 2019 Category: Endocrinology Source Type: research

Hemithyroidectomy for benign euthyroid asymmetric nodular goitre
ConclusionsAMNG is a common clinical and surgical problem. Depending on the extent of the disease and individual surgeon preferences, either unilateral or bilateral thyroidectomy can be performed. Hemithyroidecomy can be considered for some patients with AMNG and the low risk of recurrent disease as a safer alternative to total thyroidectomy but it requires life-long follow-up, is associated with a higher recurrence risk and a need for revision thyroidectomy in selected subjects. (Source: Best Practice and Research Clinical Endocrinology and Metabolism)
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 15, 2019 Category: Endocrinology Source Type: research

Gynaecology problems in puberty
Publication date: Available online 14 June 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Sonia R. Grover, DirectorAbstractWith the onset of puberty a range of problems may be encountered by the young girl. Some of these include a range of gynaecological issues relating to delayed onset of puberty, delayed menarche, atypical pubertal changes and the identification of anomalies of the genital tract. The distinction between physiological events and pathological problems is important to avoid unnecessary distress and anxiety. The onset of cyclic hormonal changes also provokes a number of �...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 15, 2019 Category: Endocrinology Source Type: research

Impact of continuous intraoperative vagus stimulation on intraoperative decision making in favor of or against bilateral surgery in benign goiter
Publication date: Available online 6 June 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Rick Schneider, Andreas Machens, Gregory Randolph, Dipti Kamani, Kerstin Lorenz, Henning DralleAbstractThe advent of continuous vagus stimulation (CVS), eliminating lag time between nerve preparation with potential trauma and stimulation, has transformed the intraoperative surgical strategy in thyroid surgery. Continuous intraoperative nerve monitoring empowers the surgeon to be optimally aware of traction-related injury to the recurrent laryngeal nerve (RLN). Electromyographic precursor lesions, cal...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 7, 2019 Category: Endocrinology Source Type: research

Value of monopolar and bipolar radiofrequency ablation for the treatment of benign thyroid nodules
Publication date: Available online 6 June 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Harald Dobnig, Karin AmreinAbstractOnly a few thyroid nodules are perceived as functional or optically disturbing. If there is a need for action, surgical intervention is the long-term standard by which thermoablative procedures (radiofrequency-, laser-, microwave ablation, high intensity focused ultrasound) must be measured against in terms of safety, effectiveness and patient satisfaction. Prior to intervention assessment of the dignity of the nodule by ultrasound-guided fine needle aspiration is e...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 7, 2019 Category: Endocrinology Source Type: research

Indications, Benefits And Risks Of Transoral Thyroidectomy
Publication date: Available online 4 June 2019Source: Best Practice & Research Clinical Endocrinology & MetabolismAuthor(s): Daqi Zhang, Dawon Park, Hui Sun, Angkoon Anuwong, Ralph Tufano, Hoon Yub Kim, Gianlorenzo DionigiAbstractThe advancement of minimally invasive surgery in the field of endocrine surgery over the last 2 decades has fostered the attempt of natural orifice transluminal endoscopic surgery (NOTES) for thyroidectomy and parathyroidectomy via oral incisions. This technically demanding surgery is currently being evaluated in a number of specialised centres. The procedure has gained popularity worldwide and is...
Source: Best Practice and Research Clinical Endocrinology and Metabolism - June 4, 2019 Category: Endocrinology Source Type: research