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Effect of axial vertical vibration on degeneration of lumbar intervertebral discs in modified bipedal rats: An in-vivo study
Conclusions This in-vivo study demonstrated that vibrations can influence the expression of anabolic genes. Furthermore, whole-body vibrations seem to have a greater effect in this regard than vertical vibrations. A new method is expected to relieve the low back pain of the patients through our research. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - July 28, 2017 Category: Tropical Medicine Source Type: research

Clinical study inpatient-reported outcomes after binocular implantation of aspheric intraocular lens of different negative spherical aberrations
Conclusion Implantation of an aspherical IOL could improve vision-related quality of life compared with a spherical IOL. However, there were no statistically significant differences in vision-related quality of life between aspheric IOLs with different negative spherical aberrations. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - July 28, 2017 Category: Tropical Medicine Source Type: research

Birds and poultries toxoplasmosis in Iran: A systematic review and meta-analysis
Conclusion Although there is a lack in data about poultries and birds toxoplasmosis in Iran, our meta-analysis revealed that infection rate is high among birds and poultries in Iran. More studies are needed to manage controlling programs and prevention strategies among poultries in Iran. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - July 28, 2017 Category: Tropical Medicine Source Type: research

Research advances on the multiple uses of Moringa oleifera: a sustainable alternative for socially neglected population
Publication date: Available online 28 July 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Raimunda Sâmia Nogueira Brilhante, Jamille Alencar Sales, Vandbergue Santos Pereira, Débora de Souza Collares Maia Castelo-Branco, Rossana de Aguiar Cordeiro, Célia Maria de Souza Sampaio, Manoel de Araújo Neto Paiva, João Bosco Feitosa dos Santos, José Júlio Costa Sidrim, Marcos Fábio Gadelha Rocha Moringa oleifera Lam (Moringaceae) is a plant with high nutritional and medicinal value. Native to India, it is now widely distributed throughout tropical and subtropical regions of the world. Its dif...
Source: Asian Pacific Journal of Tropical Medicine - July 28, 2017 Category: Tropical Medicine Source Type: research

Solvent-solvent fractionations of Combretum erythrophyllum (Burch.) leave extract: Studies of their antibacterial, antifungal, antioxidant and cytotoxicity potentials
Conclusions It can be concluded that the extracts of C. erythrophyllum are safe for medicinal use in folk medicine for treating infectious and stress related diseases. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - July 28, 2017 Category: Tropical Medicine Source Type: research

Chemical analysis and in vitro antimicrobial effects and mechanism of action of Trachyspermum copticum essential oil against Escherichia coli
Conclusions These results indicate that T. copticum EO is a good natural antibacterial agent for food-borne pathogens. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - July 28, 2017 Category: Tropical Medicine Source Type: research

Production, characterization and biological activities of acidic exopolysaccharide from marine Bacillus amyloliquefaciens 3MS 2017
Conclusions BAEPS has anti-tumor activity with a good margin of safety. The anti-tumor activity of BAEPS may be due to its content from sulfated groups and uronic acids and they have antioxidant and anti-inflammatory properties. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - July 28, 2017 Category: Tropical Medicine Source Type: research

Association between FGFR4 gene polymorphism and high-risk HPV infection cervical cancer
Conclusions The FGFR4 rs351855 polymorphism is not associated with the susceptibility of high-risk HPV cervical cancer, but patients with gene A was at higher risk of unfavourable chemotherapy prognosis compared with patients with GG. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - July 28, 2017 Category: Tropical Medicine Source Type: research

GC –MS analysis of volatile compounds of Perilla frutescens Britton var. Japonica accessions: morphological and seasonal variability
Conclusion The results revealed that the harvest time and geographical origin caused polymorphisms in the essential oil composition and morphological traits in the Perilla accessions originating from China and Japan. Therefore, these chemotypes with desirable characters might be useful for industrial exploitation and for determining the harvest time. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - July 28, 2017 Category: Tropical Medicine Source Type: research

Alternate paradigms on Zika virus-related complications: An analytical review
Publication date: Available online 28 July 2017 Source:Asian Pacific Journal of Tropical Medicine Author(s): Baburajan Radha, Gnanaraj Muniraj The proportion of the reported cases of Zika virus (ZIKV) infection reached the status of a pandemic. Numerous studies are being conducted on the isolation of ZIKV strains from various epidemics, diagnosis of the infections, various animal models and cell culture designs to study the pathogenesis of ZIKV in the attempts to find an effective ZIKV vaccine. This review focuses upon the 'Off-Spectrum' body of studies which analyses the epidemiology, pathogenesis and other attributes...
Source: Asian Pacific Journal of Tropical Medicine - July 28, 2017 Category: Tropical Medicine Source Type: research

Effect of Taoren Quyu Decoction on human endometrial cells and its anti-endometriosis activity in rats
Conclusions TQD has a significant anti-EMs effect, and its mechanism of action may be related to anti-angiogenesis and promoting apoptosis of ectopic endometrial cell. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - July 27, 2017 Category: Tropical Medicine Source Type: research

First report on molecular characterization of Leishmania species from cutaneous leishmaniasis patients in southern Khyber Pakhtunkhwa province of Pakistan
Conclusions This study is the first molecular characterization of Leishmania species in southern Khyber Pakhtunkhwa. It confirmed the previous assumptions that anthroponotic CL is the major CL form present in Khyber Pakhtunkhwa province. Furthermore, this is the first report of Leishmania major from a classical anthroponotic CL endemic focus identified in rural areas of Kohat district in southern Khyber Pakhtunkhwa. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - July 27, 2017 Category: Tropical Medicine Source Type: research

In silico identification and characterization of common epitope-based peptide vaccine for Nipah and Hendra viruses
Conclusions Data in our present study revealed the notion that the epitopes from G and M proteins might be the target for peptide-based subunit vaccine design against HeV and NiV. However, the biochemical analysis is necessary to experimentally validate the interaction of epitopes individually with the MHC molecules through elucidation of immunity induction. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - July 2, 2017 Category: Tropical Medicine Source Type: research

In  vitro and in vivo cytochrome P450 3A enzyme inhibition by Aframomum melegueta and Denniettia tripetala extracts
Conclusions Herbal preparations containing these plants' extracts should be used with caution especially in patients on CYP450 3A substrate medications. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - June 28, 2017 Category: Tropical Medicine Source Type: research

Promising antileishmanial effectiveness of doxorubicin and Doxil against Leishmania major: An in  vitro assay
Conclusions Our findings demonstrated the efficacy of both doxorubicin and its pegylated liposomal formulation on L . major at low concentrations. Further researches are needed for evaluating the safety of drugs in animal model particularly as topical formulation. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - June 23, 2017 Category: Tropical Medicine Source Type: research