Identifications of drug resistance mutations among antiretroviral treatment naive HIV-1 patients in Peninsular Malaysia
Conclusions These findings have served as an initial crucial data in determining the prevalence of transmitted HIV-1 drug resistance for the country. However, more samples from various parts of the country need to be accumulated and analyzed to provide overall HIV-1 drug resistance in the country. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 27, 2016 Category: Tropical Medicine Source Type: research

Neuroprotective effect of Spilanthes acmella Murr. on pesticide-induced neuronal cells death
Conclusion S. acmella Murr. extracts exerted neuroprotective effect, via an alteration of calcium homeostasis, against pirimicarb induced neurotoxicity. The S. acmella Murr. might be a potential natural candidate with neuroprotective activity. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 27, 2016 Category: Tropical Medicine Source Type: research

Forecasting the number of zoonotic cutaneous leishmaniasis cases in south of Fars province, Iran using seasonal ARIMA time series method
Conclusions Based on the results, leishmaniasis follows a descending trend in the study area in case drought condition continues, SARIMA models can suitably measure the disease trend, and the disease follows a seasonal trend. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 27, 2016 Category: Tropical Medicine Source Type: research

Serodiagnosis of asymptomatic dengue infection
Publication date: Available online 27 December 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Supawat Chatchen, Arunee Sabchareon, Chukiat Sirivichayakul Dengue virus (DENV) is a mosquito-transmitted virus that is expanding across the world. The incidence of dengue infection, especially severe disease, has been increasing. DENV consist of 4 serotypes of single stranded RNA viruses (D1-D4) in the genus Flavivirus, family Flaviviridae. Majority of dengue infections are asymptomatic cases, which cause difficulty in disease control and are important in dengue surveillance. There is still no gold standar...
Source: Asian Pacific Journal of Tropical Medicine - December 27, 2016 Category: Tropical Medicine Source Type: research

Situation analysis of cutaneous leishmaniasis in an endemic area,south of Iran
Conclusions This study revealed that CL is present in Kazerun country. Thus, effective monitoring and sustained suveillance system is crucial in counteracting the disease, and if possible, to eliminate it. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 27, 2016 Category: Tropical Medicine Source Type: research

Measles outbreaks in the Kyeongin area of the Republic of Korea, 2013 –2014: A single-center experience in a country of measles elimination
Conclusions Early weaning of maternally derived measles antibodies therefore vaccination of MCV1 at a young age from 9 months to 12 months should be considered in situations of early exposure. Furthermore, there is a call for consideration of scheduling an earlier age for the first dose of MMR vaccine in Europe. It is necessary for Korea to investigate the duration of the presence and quantitative analysis of maternal measles antibodies in infants and to reconsider the timing of MCV1. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 27, 2016 Category: Tropical Medicine Source Type: research

The role of heme-oxygenase-1 in pathogenesis of cerebral malaria in the co-culture model of human brain microvascular endothelial cell and ITG Plasmodium falciparum-infected red blood cells
Conclusions Results provide at least in part, insight into the contribution of HO-1 on CM pathogenesis and need to be confirmed in animal model. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 27, 2016 Category: Tropical Medicine Source Type: research

An update on the 2014 Ebola outbreak in western Africa
Publication date: Available online 27 December 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Haaris A. Shiwani, Rebabonye B. Pharithi, Barkat Khan, Christian Binoun-A-Egom, Peter Kruzliak, Vincent Maher, Emmanuel Eroume-A. Egom The recent Ebola outbreak in Western Africa was the most devastating outbreak witnessed in recent times. There have been remarkable local and international efforts to control the crisis. Ebola Virus Disease is the focus of immense research activity. The progression of events in the region has been evolving swiftly and it is of paramount importance to the medical communit...
Source: Asian Pacific Journal of Tropical Medicine - December 27, 2016 Category: Tropical Medicine Source Type: research

Prostatic abscess of Klebsiellae pneumonia complicating septic pulmonary emboli and meningitis: A case report and brief review
Publication date: Available online 28 December 2016 Source:Asian Pacific Journal of Tropical Medicine Author(s): Jai-Wen Liu, Tzu-Chieh Lin, Yao-Tien Chang, Che-An Tsai, Sung-Yuan Hu Prostatic abscess is a rare entity with an incidence of 0.5% to 2.5% in all prostate diseases and usually occurs in the 5th and 6th decades of life with immunocompromised status. Prostatic abscess might be a process of evolution from acute prostatitis. Klebsiella pneumoniae is the leading microorganism in the diabetic patients of prostatic abscess in Taiwan. A 60-year-old diabetic man, with a one-week history of acute bacterial prostati...
Source: Asian Pacific Journal of Tropical Medicine - December 27, 2016 Category: Tropical Medicine Source Type: research

Dengue fever may mislead the surgeons when it presents as an acute abdomen
Conclusions DF/DHF misleads the clinicians when it presents as AA. Initial heamatological and ultrasonographic findings may be equivocal creating a diagnostic and management dilemma. Vigilant clinical suspicion and early dengue serological assessment is advisable in equivocal cases of AAs with fever in dengue endemic areas, to confirm/exclude the infection in order to avoid unnecessary surgical morbidity in the presence of DF. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 27, 2016 Category: Tropical Medicine Source Type: research

Evaluating the safety of forsythin from Forsythia suspensa leaves by acute and sub-chronic oral administration in rodent models
Conclusion The results revealed that the forsythin from Forsythia suspensa leaves has low or no toxicity via oral administration, and therefore is suitable for further development and applications. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 27, 2016 Category: Tropical Medicine Source Type: research

Potential of Zimbabwean commercial probiotic products and strains of Lactobacillus plantarum as prophylaxis and therapy against diarrhoea caused Escherichia coli in children
Conclusions The putative Lactobacilli from four commercial Zimbabwean dairy products (Probrand sour milk, Kefalos Vuka vuka cheese and Chibuku opaque beer), and three strains of L. plantarum from Balkan cheeses (CLP1, CLP2 or CLP3) exhibited high antibacterial activities that can be harnessed to control paediatric diarrhoea that is caused by pathogenic strains of E. coli. Studies to characterise the probiotic potential of the live cultures in the products and the new strains of L. plantarum are underway. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 27, 2016 Category: Tropical Medicine Source Type: research

Antileishmanial activities of caffeic acid phenethyl ester loaded PLGA nanoparticles against Leishmania infantum promastigotes and amastigotes in vitro
Conclusions The obtained results show that (CAPE)PLGA NPs have a great potential to be especially used in treatment of visceral leishmaniasis; however, in vivo antileishmanial screening of these molecules should be performed in the near future. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - December 27, 2016 Category: Tropical Medicine Source Type: research

Influence of bioactive sulfated polysaccharide-protein complexes on hepatocarcinogenesis, angiogenesis and immunomodulatory activities
Conclusions The pronounced antitumor activity of sulfated polysaccharide-protein complexes of JCEM and EHEM is due to direct cytotoxic activity, anti-hepatocarcinogenesis, and anti-angiogenesis. In addition, JCEM, PCEM and EHEM had an immunostimulatory response and improved the humoral immune response in HCC induced rats. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 15, 2016 Category: Tropical Medicine Source Type: research

Novel neuroprotective and hepatoprotective effects of citric acid in acute malathion intoxication
Conclusions The study demonstrates a beneficial effect for citric acid upon brain oxidative stress, neuronal injury, liver and DNA damage due to acute malathion exposure. (Source: Asian Pacific Journal of Tropical Medicine)
Source: Asian Pacific Journal of Tropical Medicine - November 15, 2016 Category: Tropical Medicine Source Type: research